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Ultra CoQ10 100 mg

Qunol
4.8
★ ★ ★ ★ ★
(55456 ratings)
Coenzyme Q-10 100 mg
Product Image
Score79
A well-priced softgel combines a sensible CoQ10 amount with delivery suited to a fat-soluble active. Missing molecular-form details keep it below the most transparent options.
How scoring works
Quantity:30 Softgel(s) • (30 servings)
Goals:
Heart Health
Metabolism Boost
Anti-Aging
Cardiovascular Support
Anti-Inflammatory Support
Energy

Score 79

A well-priced softgel combines a sensible CoQ10 amount with delivery suited to a fat-soluble active. Missing molecular-form details keep it below the most transparent options.
How scoring works
$10.88($0.36 per serving)
iHerb
$ 12.38
Vitacost
$ 13.89
Walmart
$ 10.88
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Analysis

The 100 mg CoQ10 serving provides focused support for mitochondrial energy and antioxidant activity without moving into an aggressive dose range. A small amount of vitamin E adds compatible lipid-phase antioxidant support.

Softgel delivery is well suited to a fat-soluble compound and is a meaningful advantage over a dry capsule. The label still does not identify ubiquinol, ubiquinone, or a specific absorption system, which limits comparison with more transparent formulas.

The combination offers good everyday value for people seeking a moderate dose in an easy one-softgel serving. CoQ10 may reduce warfarin response, so users of that medicine should coordinate monitoring when starting or stopping it.

Who is it for
  • Adults seeking everyday CoQ10 maintenance
  • People who prefer softgels
  • Value-conscious users wanting focused heart-energy support
Best for
  • Balanced daily CoQ10 use
  • Softgel delivery
  • Moderate-dose mitochondrial support

Pros

  • Practical 100 mg serving
  • Fat-compatible softgel format
  • Favorable serving value
  • Includes complementary vitamin E

Cons

  • CoQ10 molecular form is not identified
  • No specific absorption technology is disclosed
  • Vitamin E is the synthetic form

Warnings

  • CoQ10 may reduce warfarin response; anticoagulation monitoring may need adjustment when supplementation changes.

Nutrient quality

83 Highest impact

Softgel delivery suits fat-soluble CoQ10, although the molecular form and oil carrier are not identified. The CoQ10 amount is useful for general maintenance.

Ingredient transparency

76 High impact

Specific amounts are disclosed for every listed active ingredient. Calories and active vitamin E are disclosed, but the full softgel excipients and oil carrier are not provided.

Customer satisfaction

74 High impact

The supplied average rating is very strong. The large rating sample provides strong statistical confidence.

Value for money

84 Highest impact

A practical amount and absorption-friendly format support good quality. The favorable serving cost provides good value for a softgel formula.

Report analysis

Goals

Heart Health
Impact
Highest effect
A- Goal FitB+ Strength of SupportC- CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 provides direct support for mitochondrial energy production in heart muscle and also acts as an antioxidant. The 100 mg amount is meaningful, particularly for people whose CoQ10 status may be reduced by statin therapy.

The exact active amount is clear, but the label does not identify ubiquinol, enhanced delivery, or antioxidant protection for the oil. CoQ10 may reduce the effect of warfarin in some users, so anticoagulation monitoring may need adjustment.

Study evidence
Coenzyme Q-10 Supportive 114 studies
Metabolism Boost
Impact
Highest effect
A- Goal FitA- Strength of SupportC- CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 directly supports mitochondrial electron transport and cellular ATP production. The 100 mg amount offers useful focused support without acting as a stimulant or thermogenic.

Softgel delivery suits the fat-soluble active, although the supplied label does not identify ubiquinone, ubiquinol, or an absorption system. CoQ10 may reduce warfarin’s anticoagulant effect, so users of that medicine need medication-specific guidance.

Study evidence
Coenzyme Q-10 Disputed 11 studies
Anti-Aging
Impact
High effect
B+ Goal FitB Strength of SupportC- CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

A 100 mg CoQ10 serving supports mitochondrial energy and antioxidant protection, while vitamin E adds a small lipid-phase antioxidant role. Evidence is strongest for selected cardiovascular contexts rather than slowing biological aging broadly.

The active amounts are transparent, but the product does not identify ubiquinol or an optimized lipid carrier and uses synthetic vitamin E. CoQ10 may reduce warfarin response in some users, so INR monitoring matters when they are combined.

Study evidence
Coenzyme Q-10 Supportive 6 studies
Vitamin E Supportive 19 studies
Cardiovascular Support
Impact
High effect
B+ Goal FitB+ Strength of SupportD+ CoverageA Formula Quality
Coenzyme Q-10 · 100 mgVitamin E · 6 mg

Coenzyme Q10 directly supports cardiac mitochondrial energy and may be especially relevant during statin use. Human evidence supports modest benefits in selected heart-failure and statin-related contexts, though results vary by population.

The 100 mg amount is a practical daily dose. Vitamin E is a compatible antioxidant companion to CoQ10.

Study evidence
Coenzyme Q-10 Supportive 89 studies
Vitamin E Mixed 79 studies
Anti-Inflammatory Support
Impact
High effect
C+ Goal FitB Strength of SupportC CoverageA Formula Quality
Coenzyme Q-10 · 100 mgVitamin E · 6 mg

CoQ10 offers antioxidant and mitochondrial support that may modestly influence systemic inflammatory markers. Vitamin E adds a complementary lipid-phase antioxidant but does not make the formula a direct inflammatory-enzyme inhibitor.

The 100 mg CoQ10 amount meets a commonly studied starting level, and softgel delivery supports absorption. The CoQ10 molecular form is not identified, while synthetic vitamin E provides only a modest companion amount.

Study evidence
Coenzyme Q-10 Supportive 46 studies
Vitamin E Supportive 20 studies
Energy
Impact
High effect
C+ Goal FitB- Strength of SupportC- CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

Coenzyme Q10 provides focused support for cellular energy and antioxidant activity, while vitamin E adds a complementary antioxidant. The CoQ10 amount is clearly disclosed and meaningful for targeted use.

The formula is narrower than a broad daily wellness product and uses synthetic vitamin E. No enhanced CoQ10 form or absorption-focused oil carrier is identified in the supplied active details.

Study evidence
Coenzyme Q-10 Supportive 32 studies

Ingredients

IngredientAmount per serving
Calories
7 Calorie(s)
Vitamin E (DL-Alpha-Tocopheryl Acetate)
6 mg
Coenzyme Q10
100 mg
Adults 18–50 Dairy Free
Report overview
Coenzyme Q-10 · 100 mg OverallScore61
D- Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyC Value

The one-softgel serving supplies a useful maintenance amount with an absorption-friendly format. The molecular form and specific delivery technology are not detailed in the supplied data. Its serving cost is close to the collection midpoint and offers reasonable value.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Ubiquinol-10 Intake Is Effective in Relieving Mild Fatigue in Healthy Individuals.
    Mizuno K; Sasaki AT; Watanabe K; Watanabe Y · Nutrients · 2021
    Clinical trial62 participantsEnergy forCoenzyme Q-10
  2. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  3. Coenzyme Q10 supplementation increases blood concentrations but shows limited and inconsistent effects on exercise performance: a systematic review and meta-analysis.
    Deng H; Song T; Yin M; Xu K; Zhong Y; Mohd NB; Naharudin MNB; Yusof A; Fan X · The British journal of nutrition · 2026
    Meta-analysis24 studies pooledEnergy forCoenzyme Q-10
  4. A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer.
    Lesser GJ; Case D; Stark N; Williford S; Giguere J; Garino LA; Naughton MJ; Vitolins MZ; Lively MO; Shaw EG; Wake Forest University Community Clinical Oncology Program Research Base · The journal of supportive oncology · 2013
    Randomized trial236 participantsEnergy forCoenzyme Q-10
  5. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewAnti-Aging forCoenzyme Q-10
  6. Coenzyme Q10 Supplementation in Aging and Disease.
    Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
    Narrative reviewAnti-Aging forCoenzyme Q-10
  7. Coenzyme Q10, a cutaneous antioxidant and energizer.
    Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
    Clinical trialAnti-Aging forCoenzyme Q-10
  8. Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
    Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
    Cross-sectional study4,260 participantsAnti-Aging forCoenzyme Q-10
  9. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsAnti-Aging forCoenzyme Q-10
  10. Low dietary vitamin E intake is associated with high risk of incident dementia among older adults: The Shanghai Aging Study.
    Liu S; Luo J; Xiao Z; Wu W; Liang X; Ding S; Zhao Q; Zhao X; Wang Y; Ding D · Frontiers in nutrition · 2024
    Cohort study1,550 participantsAnti-Aging forVitamin E
  11. Nutrients and bioactives in green leafy vegetables and cognitive decline: Prospective study.
    Morris MC; Wang Y; Barnes LL; Bennett DA; Dawson-Hughes B; Booth SL · Neurology · 2019
    Cohort study960 participantsAnti-Aging forVitamin E
  12. Low Intake of Vitamin E Accelerates Cellular Aging in Patients With Established Cardiovascular Disease: The CORDIOPREV Study.
    Corina A; Rangel-Zúñiga OA; Jiménez-Lucena R; Alcalá-Díaz JF; Quintana-Navarro G; Yubero-Serrano EM; López-Moreno J; Delgado-Lista J; Tinahones F; Ordovás JM; López-Miranda J; Pérez-Martínez P · The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
    Observational study1,002 participantsAnti-Aging forVitamin E
  13. The L-shaped link between total antioxidant capacity and phenotypic age acceleration: evidence from NHANES 2003-2010.
    Wu Y; Xiang M; Zhao Y; Zhang Y; Cheng W; Deng J · Biogerontology · 2025
    Cross-sectional study16,395 participantsAnti-Aging forVitamin E
  14. Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults.
    Mangialasche F; Solomon A; Kåreholt I; Hooshmand B; Cecchetti R; Fratiglioni L; Soininen H; Laatikainen T; Mecocci P; Kivipelto M · Experimental gerontology · 2014
    Cohort study140 participantsAnti-Aging forVitamin E
  15. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  16. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  17. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  18. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  19. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  20. Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
    Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
    Randomized trial110 participantsAnti-Inflammatory Support forVitamin E
  21. Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
    Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
    Meta-analysis495 participants12 studies pooledAnti-Inflammatory Support forVitamin E
  22. Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
    Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
    Meta-analysis46 studies pooledAnti-Inflammatory Support forVitamin E
  23. Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
    Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
    Meta-analysis8 studies pooledAnti-Inflammatory Support forVitamin E
  24. Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
    Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
    Randomized trial71 participantsAnti-Inflammatory Support forVitamin E
  25. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  26. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  27. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  28. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  29. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  30. Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis.
    Loffredo L; Perri L; Di Castelnuovo A; Iacoviello L; De Gaetano G; Violi F · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2016
    Meta-analysis16 studies pooledCardiovascular Support forVitamin E
  31. Vitamin E ameliorates blood cholesterol level and alters gut microbiota composition: A randomized controlled trial.
    Chen B; Li Y; Li Z; Hu X; Zhen H; Chen H; Nie C; Hou Y; Zhu S; Xiao L; Li T · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2025
    Randomized trial90 participantsCardiovascular Support forVitamin E
  32. Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial.
    Lonn E; Bosch J; Yusuf S; Sheridan P; Pogue J; Arnold JM; Ross C; Arnold A; Sleight P; Probstfield J; Dagenais GR; HOPE and HOPE-TOO Trial Investigators · JAMA · 2005
    Randomized trial9,541 participantsCardiovascular Support forVitamin E
  33. Independent and combined associations of dietary antioxidant exposure with all-cause and cause-specific mortality in the general population.
    Liu Z; He Z; Xing Y · Journal of nutritional science · 2026
    Cohort study34,955 participantsCardiovascular Support forVitamin E
  34. Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study.
    Chin SF; Ibahim J; Makpol S; Abdul Hamid NA; Abdul Latiff A; Zakaria Z; Mazlan M; Mohd Yusof YA; Abdul Karim A; Wan Ngah WZ · Nutrition & metabolism · 2011
    Randomized trial62 participantsCardiovascular Support forVitamin E
  35. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  36. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  37. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  38. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  39. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  40. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  41. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Boost forCoenzyme Q-10
  42. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  43. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  44. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forCoenzyme Q-10
  45. Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
    Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
    Randomized trial100 participantsMetabolism Boost forCoenzyme Q-10
  46. The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
    Ahmadi Asouri S; Asemi R; Aghadavod E; Jamilian M · Annals of medicine and surgery (2012) · 2024
    Randomized trial40 participantsMetabolism Boost forCoenzyme Q-10