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Super Selenium Complex 200 mcg & Vitamin E

Life Extension
4.8
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(39093 ratings)
Selenium 200 mcg
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Score82
A good-value selenium and natural vitamin E combination whose unspecified selenium form limits transparency.
How scoring works
Quantity:100 Capsule(s) • (100 servings)
Goals:
Immunity
General Health

Score 82

A good-value selenium and natural vitamin E combination whose unspecified selenium form limits transparency.
How scoring works
$10.50($0.10 per serving)
Pure Formulas
$ 10.50
iHerb
$ 10.50
Amazon
$ 10.50
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Analysis

The capsule combines 200 mcg selenium with 20.1 mg vitamin E as d-alpha-tocopheryl succinate. That pairing supports normal antioxidant defenses and immune function without a long ingredient list.

The selenium form is not identified in the supplied data, which prevents comparison with selenomethionine or yeast-based products. Capsule excipients and allergen details are also absent.

The simple daily format and favorable value suit targeted selenium use. Users should account for selenium from multivitamins because the dose is already substantial.

Who is it for
  • Adults seeking selenium with vitamin E
  • People wanting a simple antioxidant-focused formula
Best for
  • Selenium supplementation
  • Combined selenium and vitamin E support

Pros

  • Provides 200 mcg selenium
  • Uses natural-form vitamin E
  • Simple two-active formula

Cons

  • Selenium form is not disclosed
  • Non-active ingredients are missing
  • Not a broad multivitamin

Warnings

  • Count the 200 mcg selenium amount alongside multivitamins and other selenium products.

Nutrient quality

85 Highest impact

Natural-form vitamin E and a meaningful selenium amount support the intended use. Unspecified selenium chemistry limits confidence in absorption, although the focused formula avoids obvious filler.

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Ingredient transparency

77 High impact

Active amounts and serving count are supplied, and no hidden blend is shown. Daily-use directions and non-active ingredients are missing, while the selenium source remains unspecified.

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Customer satisfaction

72 High impact

The available rating is strong and the sample is very large. Detailed feedback was not supplied, so repeated complaints and alignment with the intended use remain uncertain.

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Value for money

95 Highest impact

Meaningful amounts and a long supply support strong practical value. The unknown selenium form is the main quality limitation, but unnecessary extras do not raise the cost.

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Goals

Immunity
Impact
Highest effect
A- Goal FitB Strength of SupportC+ CoverageA Formula Quality
Selenium · 200 mcg

Selenium supports antioxidant enzymes and controlled immune-cell activity, while vitamin E adds complementary antioxidant protection. The 200 mcg selenium amount reaches a useful target and leaves a practical margin below the adult upper intake level.

The two-nutrient formula is focused and provides depth for oxidative-stress control. Missing selenium form information prevents a reliable judgment about absorption quality.

Study evidence
Selenium Mixed 37 studies
Vitamin E Supportive 21 studies
General Health
Impact
High effect
A- Goal FitB Strength of SupportC+ CoverageA- Formula Quality
Selenium · 200 mcg

Selenium supports antioxidant enzymes, thyroid hormone metabolism, and immune function, while vitamin E adds complementary antioxidant activity. The serving provides a meaningful selenium amount with a sensible margin below the daily upper limit.

The supplied data do not name the selenium compound, so absorption quality cannot be judged. Clearer form disclosure would materially improve confidence in routine use.

Study evidence
Selenium Supportive 70 studies

Ingredients

IngredientAmount per serving
Vitamin E (D-Alpha-Tocopheryl Succinate)
20.1 mg
Selenium
200 mcg
Adults 18–50
Report overview
Selenium · 200 mcg OverallScore60
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The serving reaches the preferred selenium amount and remains comfortably below the daily upper limit. The supplied label does not identify any selenium compound, so the quality of its blend cannot be verified from the available data. Its low standardized cost still makes it attractive for shoppers who accept that disclosure limitation.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Selenium supplementation has beneficial and detrimental effects on immunity to influenza vaccine in older adults.
    Ivory K; Prieto E; Spinks C; Armah CN; Goldson AJ; Dainty JR; Nicoletti C · Clinical nutrition (Edinburgh, Scotland) · 2018
    Randomized trial117 participantsImmunity forSelenium
  2. Selenium and immune function: a systematic review and meta-analysis of experimental human studies.
    Filippini T; Fairweather-Tait S; Vinceti M · The American journal of clinical nutrition · 2023
    Meta-analysis9 studies pooledImmunity forSelenium
  3. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  4. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  5. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  6. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health forSelenium
  7. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  8. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  9. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  10. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  11. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  12. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium
  13. Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects.
    Meydani SN; Barklund MP; Liu S; Meydani M; Miller RA; Cannon JG; Morrow FD; Rocklin R; Blumberg JB · The American journal of clinical nutrition · 1990
    Randomized trial32 participantsImmunity forVitamin E
  14. Immunomodulatory effects of palm-derived tocotrienol-rich fraction in healthy volunteers following influenza vaccination: A randomised clinical trial.
    Chen S; Ahmad B; Palanisamy UD; Hafid SRA; Selvaduray KR; Radhakrishnan AK · Nutrition research (New York, N.Y.) · 2026
    Randomized trial150 participantsImmunity forVitamin E
  15. Effects of supplementation with tocotrienol-rich fraction on immune response to tetanus toxoid immunization in normal healthy volunteers.
    Mahalingam D; Radhakrishnan AK; Amom Z; Ibrahim N; Nesaretnam K · European journal of clinical nutrition · 2011
    Randomized trialImmunity forVitamin E
  16. Vitamin E and beta-carotene supplementation and hospital-treated pneumonia incidence in male smokers.
    Hemilä H; Virtamo J; Albanes D; Kaprio J · Chest · 2004
    Randomized trial29,133 participantsImmunity forVitamin E
  17. Vitamin E supplementation and in vivo immune response in healthy elderly subjects. A randomized controlled trial.
    Meydani SN; Meydani M; Blumberg JB; Leka LS; Siber G; Loszewski R; Thompson C; Pedrosa MC; Diamond RD; Stollar BD · JAMA · 1997
    Randomized trial88 participantsImmunity forVitamin E