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Ubiquinol 150 mg

Dr. Mercola
4.7
★ ★ ★ ★ ★
(341 ratings)
Coenzyme Q-10 150 mg
Product Image
Score80
Ubiquinol at 150 mg provides substantial CoQ10 support, with the lack of a lipid carrier as the main trade-off.
How scoring works
Quantity:30 Capsule(s) • (30 servings)
Goals:
Heart Health
Energy
Anti-Aging
Cardiovascular Support
Metabolism Boost
Anti-Inflammatory Support

Score 80

Ubiquinol at 150 mg provides substantial CoQ10 support, with the lack of a lipid carrier as the main trade-off.
How scoring works

Also available as

5 options
100.00mg • 90 Capsule(s) servings Coenzyme Q-10 100 mg • 90 Capsule(s) • 90 servings $68.07 ($0.75 per serving) 100.00mg • 30 Capsule(s) servings Coenzyme Q-10 100 mg • 30 Capsule(s) • 30 servings $23.43 ($0.78 per serving) 90 servings Coenzyme Q-10 150 mg • 90 Capsule(s) • 90 servings $87.99 ($0.97 per serving) 200.00mg • 90 Capsule(s) servings Coenzyme Q-10 200 mg • 90 Capsule(s) • 90 servings $114.39 ($1.27 per serving) 200.00mg • 30 Capsule(s) servings Coenzyme Q-10 200 mg • 30 Capsule(s) • 30 servings $43.99 ($1.46 per serving)
$32.99($1.09 per serving)
iHerb
$ 32.99
Vitacost
$ 37.49
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Analysis

Ubiquinol is supplied at 150 mg in one capsule. The amount suits adults seeking more than basic maintenance support. The dry capsule is convenient but does not disclose a lipid carrier or absorption enhancer.

CoQ10 participates in cellular energy production and may support heart and muscle energy needs. The single-active design keeps the purpose and dose easy to assess. Ubiquinol is the reduced form and generally offers an absorption advantage over ubiquinone.

The 30-serving bottle provides a short trial, and value is weak. Taking the serving with a meal containing fat may improve practical uptake. Warfarin users need monitoring because CoQ10 can reduce anticoagulant response.

Who is it for
  • Adults seeking substantial CoQ10 support
  • People who prefer a capsule format
Best for
  • Mitochondrial energy support
  • Heart and muscle energy routines

Pros

  • 150 mg active amount is clearly listed
  • Uses the reduced ubiquinol form
  • Simple capsule format
  • Focused single-active formula

Cons

  • No absorption enhancer is disclosed
  • Dry capsule lacks a lipid carrier
  • Value is limited for the amount and delivery

Warnings

  • CoQ10 may reduce warfarin response, so clotting control can change when supplementation starts or stops.
  • CoQ10 may add to blood-pressure-lowering medicines and cause lightheadedness in sensitive users.
  • CoQ10 can cause nausea, loose stools, or insomnia in sensitive users.

Nutrient quality

95 Highest impact

Ubiquinol provides a well-absorbed CoQ10 form in a meaningful amount. The formula is focused and avoids an obvious excess at the supplied amount.

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Ingredient transparency

84 Highest impact

Active amounts are clear and no hidden blend is present. The CoQ10 form is specific, but daily-use directions and non-active ingredients are missing.

.

Customer satisfaction

64 Moderate impact

The available rating is strong and the sample is moderate. Detailed feedback was not supplied, so repeated complaints and alignment with the intended use remain uncertain.

.

Value for money

69 High impact

The formula and supply provide moderate value for the active amount. Unnecessary extras do not materially inflate the cost.

.
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Goals

Heart Health
Heart Health
Impact
Highest effect
A- Goal FitA+ Strength of SupportC+ CoverageA+ Formula Quality
Coenzyme Q-10 · 150 mg

Ubiquinol directly supports mitochondrial energy production in heart muscle and provides lipid-soluble antioxidant activity. Its evidence is most relevant in selected settings such as low CoQ10 status or statin use rather than as complete cardiovascular coverage.

The 150 mg amount is substantial and the reduced ubiquinol form is readily usable. CoQ10 may reduce the anticoagulant response to warfarin, so clotting control may need closer monitoring when the two are combined.

Study evidence
Coenzyme Q-10 Supportive 114 studies
Energy
Energy
Impact
Highest effect
A Goal FitA- Strength of SupportC CoverageA+ Formula Quality
Coenzyme Q-10 · 150 mg

Ubiquinol supplies a substantial amount of readily used CoQ10 for mitochondrial energy production. The single-capsule formula is transparent and stimulant free.

No lipid carrier or absorption enhancer is disclosed, which may limit uptake compared with a fat-based softgel. Coverage remains focused on one cellular-energy pathway rather than broader alertness or stress support.

Study evidence
Coenzyme Q-10 Supportive 32 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
A- Goal FitA Strength of SupportC CoverageA+ Formula Quality
Coenzyme Q-10 · 150 mg

Ubiquinol directly supports mitochondrial energy and antioxidant protection relevant to healthy aging. The 150 mg amount provides strong targeted depth in the preferred reduced form.

No lipid carrier or absorption enhancer is identified for the capsule. The narrow formula does not extend into structural, inflammatory, or neurological aging pathways beyond mitochondrial support.

Study evidence
Coenzyme Q-10 Supportive 6 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
A Goal FitA- Strength of SupportC- CoverageA+ Formula Quality
Coenzyme Q-10 · 150 mg

Ubiquinol directly supports heart-muscle energy and provides a well-supported cardiovascular active. The disclosed amount is meaningful, but the standard capsule lists no oil carrier or other absorption aid.

The formula offers excellent depth for mitochondrial energy and antioxidant support. Its narrow scope leaves lipids, vascular tone, and rhythm unaddressed, yet the single-ingredient design remains clear and efficient.

Study evidence
Coenzyme Q-10 Supportive 89 studies
Metabolism Boost
Metabolism Boost
Impact
Highest effect
B Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Coenzyme Q-10 · 150 mg

A strong ubiquinol amount provides focused support for mitochondrial energy production. It does not add thermogenic, thyroid, or glycemic pathways.

The formula supports cellular energy more directly than calorie expenditure. Benefits may be more noticeable in users with elevated CoQ10 needs.

Study evidence
Coenzyme Q-10 Disputed 11 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
B- Goal FitB+ Strength of SupportD+ CoverageA+ Formula Quality
Coenzyme Q-10 · 150 mg

Ubiquinol supplies a favorable CoQ10 form at a meaningful amount for mitochondrial and antioxidant support. CoQ10 may help moderate some inflammatory markers by reducing oxidative strain.

The focused formula clearly states its only active ingredient. No lipid carrier or enhanced-delivery system is disclosed, which limits confidence in absorption support.

Study evidence
Coenzyme Q-10 Supportive 46 studies

Ingredients

IngredientAmount per serving
Ubiquinol
150 mg
Adults 18–50
Report overview
Coenzyme Q-10 · 150 mg OverallScore70
B- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value

Ubiquinol provides the preferred reduced form at a solid therapeutic amount. The one-capsule serving is convenient, but no lipid carrier or absorption enhancer is disclosed. Its high serving cost weakens value despite the suitable active form and dose.

View ingredientView products
Loading alternative details
87 Performance

Extra Strength Ubiquinol 200 mg

NOW
Reduced ubiquinol at 200 mg in a softgel combines a readily absorbed form with a substantial amount for targeted use. Compared with the original, it raises the listed CoQ10 amount from 150 mg to 200 mg and retains the original's reduced ubiquinol form, giving a well-specified option for the same CoQ10 goals.
85 Performance

Mega Ubiquinol CoQ10 100 mg

Qunol
Reduced ubiquinol at 100 mg in a softgel provides a clearly stated maintenance amount, while the small fat-soluble vitamin C addition contributes limited extra value. Compared with the original, it uses a lower listed CoQ10 amount than the original's 150 mg and retains the original's reduced ubiquinol form, giving a well-specified option for the same CoQ10 goals.
87 Performance

QH-absorb 100 mg

Jarrow Formulas
Reduced ubiquinol at 100 mg provides a clearly stated maintenance amount, while CoQ10 may reduce warfarin's anticoagulant effect. Compared with the original, it uses a lower listed CoQ10 amount than the original's 150 mg and retains the original's reduced ubiquinol form, giving a well-specified option for the same CoQ10 goals.
86 Budget

CoQ10 100 mg

Lake Avenue Nutrition
A clearly identified 100 mg ubiquinone amount offers focused CoQ10 support, though the dry capsule lacks a listed lipid carrier. Compared with the original, it uses a lower listed CoQ10 amount than the original's 150 mg and uses conventional ubiquinone instead of the original's reduced form, while lowering recurring cost.
85 Budget

High Absorption CoQ10 with BioPerine 100 mg

Doctor's Best
A 100 mg ubiquinone amount with 5 mg of piperine targets absorption, but the dry capsule lacks a lipid carrier and piperine may alter the handling of some medicines. Compared with the original, it uses a lower listed CoQ10 amount than the original's 150 mg and uses conventional ubiquinone instead of the original's reduced form, while lowering recurring cost.
84 Budget

CoQ10 100 mg

California Gold Nutrition
A 100 mg ubiquinone amount in a softgel supports uptake of the fat-soluble active, while CoQ10 may reduce warfarin's anticoagulant effect. Compared with the original, it uses a lower listed CoQ10 amount than the original's 150 mg and uses conventional ubiquinone instead of the original's reduced form, while lowering recurring cost.
84 Value

CoQ10 100 mg

Best Naturals
A 100 mg ubiquinone amount provides focused CoQ10 support, though the dry capsule has no stated lipid carrier and CoQ10 may reduce warfarin response. Compared with the original, it uses a lower listed CoQ10 amount than the original's 150 mg and uses conventional ubiquinone instead of the original's reduced form, while the lower recurring cost strengthens practical value.
83 Value

CoQ10 100 mg plus BioPerine

Lake Avenue Nutrition
A 100 mg ubiquinone amount in a softgel supports uptake, while 5 mg of black pepper extract may change exposure to some medicines. Compared with the original, it uses a lower listed CoQ10 amount than the original's 150 mg and uses conventional ubiquinone instead of the original's reduced form, while the lower recurring cost strengthens practical value.
82 Value

CoQ10 100 mg wtih BioPerine

California Gold Nutrition
A 100 mg ubiquinone amount with 5 mg of piperine offers a focused formula, but the dry capsule lacks a lipid carrier and piperine may alter medicine exposure. Compared with the original, it uses a lower listed CoQ10 amount than the original's 150 mg and uses conventional ubiquinone instead of the original's reduced form, while the lower recurring cost strengthens practical value.
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  2. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  3. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  4. Coenzyme Q10 supplementation increases blood concentrations but shows limited and inconsistent effects on exercise performance: a systematic review and meta-analysis.
    Deng H; Song T; Yin M; Xu K; Zhong Y; Mohd NB; Naharudin MNB; Yusof A; Fan X · The British journal of nutrition · 2026
    Meta-analysis24 studies pooledEnergy forCoenzyme Q-10
  5. A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer.
    Lesser GJ; Case D; Stark N; Williford S; Giguere J; Garino LA; Naughton MJ; Vitolins MZ; Lively MO; Shaw EG; Wake Forest University Community Clinical Oncology Program Research Base · The journal of supportive oncology · 2013
    Randomized trial236 participantsEnergy forCoenzyme Q-10
  6. Platelet mitochondrial function and endogenous coenzyme Q10 levels are reduced in patients after COVID-19.
    Sumbalova Z; Kucharska J; Palacka P; Rausova Z; Langsjoen PH; Langsjoen AM; Gvozdjakova A · Bratislavske lekarske listy · 2022
    Cross-sectional study25 participantsEnergy forCoenzyme Q-10
  7. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledHeart Health Cardiovascular Support forCoenzyme Q-10
  8. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  9. Effect of coenzyme Q₁₀ supplementation on heart failure: a meta-analysis.
    Fotino AD; Thompson-Paul AM; Bazzano LA · The American journal of clinical nutrition · 2013
    Meta-analysisHeart Health forCoenzyme Q-10
  10. Efficacy of coenzyme Q10 in patients with cardiac failure: a meta-analysis of clinical trials.
    Lei L; Liu Y · BMC cardiovascular disorders · 2018
    Meta-analysis2,149 participants14 studies pooledHeart Health forCoenzyme Q-10
  11. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension.
    Ho MJ; Li EC; Wright JM · The Cochrane database of systematic reviews · 2016
    Meta-analysis50 participants3 studies pooledHeart Health forCoenzyme Q-10
  12. Coenzyme Q10: an independent predictor of mortality in chronic heart failure.
    Molyneux SL; Florkowski CM; George PM; Pilbrow AP; Frampton CM; Lever M; Richards AM · Journal of the American College of Cardiology · 2008
    Cohort study236 participantsHeart Health forCoenzyme Q-10
  13. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewAnti-Aging forCoenzyme Q-10
  14. Coenzyme Q10 Supplementation in Aging and Disease.
    Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
    Narrative reviewAnti-Aging forCoenzyme Q-10
  15. Coenzyme Q10, a cutaneous antioxidant and energizer.
    Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
    Clinical trialAnti-Aging forCoenzyme Q-10
  16. Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
    Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
    Cross-sectional study4,260 participantsAnti-Aging forCoenzyme Q-10
  17. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsAnti-Aging forCoenzyme Q-10
  18. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  19. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  20. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  21. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  22. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  23. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  24. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  25. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  26. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  27. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  28. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  29. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  30. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Boost forCoenzyme Q-10
  31. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  32. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  33. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forCoenzyme Q-10
  34. Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
    Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
    Randomized trial100 participantsMetabolism Boost forCoenzyme Q-10
  35. The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
    Ahmadi Asouri S; Asemi R; Aghadavod E; Jamilian M · Annals of medicine and surgery (2012) · 2024
    Randomized trial40 participantsMetabolism Boost forCoenzyme Q-10