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Coenzyme Q10 100 mg

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4.7
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(14071 ratings)
Coenzyme Q-10 100 mg
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Score84
100 mg of ubiquinone is a strong single-ingredient option with strong value. Its main trade-off is the standard dose, which may be either convenient or restrictive depending on the intended routine.
How scoring works
Quantity:120 Softgel(s) • (120 servings)
Goals:
Energy
Cardiovascular Support
Anti-Aging
Heart Health
Metabolism Boost
Anti-Inflammatory Support

Score 84

100 mg of ubiquinone is a strong single-ingredient option with strong value. Its main trade-off is the standard dose, which may be either convenient or restrictive depending on the intended routine.
How scoring works

Also available as

7 options
50.00mg • 120 Softgel(s) servings Coenzyme Q-10 50 mg • 120 Softgel(s) • 120 servings $18.17 ($0.15 per serving) 50.00mg • 60 Softgel(s) servings Coenzyme Q-10 50 mg • 60 Softgel(s) • 60 servings $11.17 ($0.18 per serving) 60 servings Coenzyme Q-10 100 mg • 60 Softgel(s) • 60 servings $16.07 ($0.26 per serving) 30 servings Coenzyme Q-10 100 mg • 30 Softgel(s) • 30 servings $9.07 ($0.30 per serving) 200.00mg • 60 Softgel(s) servings Coenzyme Q-10 200 mg • 60 Softgel(s) • 60 servings $25.17 ($0.41 per serving) 200.00mg • 30 Softgel(s) servings Coenzyme Q-10 200 mg • 30 Softgel(s) • 30 servings $13.97 ($0.46 per serving) 400.00mg • 60 Softgel(s) servings Coenzyme Q-10 400 mg • 60 Softgel(s) • 60 servings $48.97 ($0.81 per serving)
$27.97($0.23 per serving)
Pure Formulas
$ 27.97
Vitacost
$ 27.97
iHerb
$ 27.97
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Analysis

The 100 mg serving uses ubiquinone, giving a clear and focused CoQ10 option. The amount is best suited to people looking for a standard intake rather than a broad multi-ingredient formula.

The label clearly identifies the Ubiquinone form and the amount per serving. Value is favorable for the supplied amount and serving count, and the simple formula makes comparison with other CoQ10 products easier.

The strongest practical fit is energy, with related assessments also supporting general cardiovascular and energy-focused use. The main decision is whether 100 mg and the ubiquinone form match the user's preferred dose and budget.

Who is it for
  • Adults seeking a standard-dose CoQ10 supplement
  • People who prefer ubiquinone in softgel(s)
  • Users focused on energy
Best for
  • Energy support
  • Cardiovascular Support support
  • Anti-Aging support

Pros

  • Clearly stated 100 mg amount
  • Focused ubiquinone formula
  • Good disclosure of form and serving amount
  • Favorable value for the supplied quantity

Cons

  • 100 mg may not match users seeking a lower or higher amount
  • Ubiquinone may not suit buyers specifically seeking ubiquinol
  • Single-active formula provides no complementary nutrients

Warnings

  • CoQ10 can affect the response to warfarin; people using warfarin should discuss this ingredient with the clinician managing anticoagulation.
  • CoQ10 may add to the effect of blood-pressure-lowering medicines, so users taking them may need appropriate monitoring.

Nutrient quality

90 Highest impact

Ubiquinone is an established form that requires conversion, while the softgel supports delivery of this fat-soluble ingredient. The dose is well aligned with general maintenance and common targeted use, while the focused design avoids unrelated actives.

Ingredient transparency

83 Highest impact

The active amount is clearly disclosed and no blend hides it. Complete daily-use directions and inactive ingredients are not supplied.

Customer satisfaction

70 High impact

The aggregate rating is favorable, and the very large review count makes it stable. No detailed feedback is supplied, so repeated complaints and purpose fit cannot be judged.

Value for money

93 Highest impact

The large package offers excellent economics for a clearly identified maintenance dose. Incomplete inactive-ingredient details are the main remaining value limitation.

Report analysis

Goals

Energy
Energy
Impact
Highest effect
A Goal FitB+ Strength of SupportC- CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinone directly supports mitochondrial electron transport, a core step in cellular energy production. The 100 mg amount provides practical maintenance support in one softgel.

The formula is focused on mitochondrial energy and does not address alertness or stress-resilience pathways. The softgel offers lipid-compatible delivery, although no carrier oil is identified in the supplied actives.

Study evidence
Coenzyme Q-10 Supportive 32 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
A- Goal FitA- Strength of SupportC CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 supports mitochondrial energy production in heart muscle and provides lipid-phase antioxidant activity. The ubiquinone amount is meaningful, and the softgel format may aid delivery of this fat-soluble compound.

The formula remains narrowly focused and does not address omega-3 status, mineral balance, arterial calcium handling, or soluble fiber. CoQ10 may reduce warfarin’s anticoagulant effect, so people using warfarin need clinician-guided monitoring when starting or stopping it.

Study evidence
Coenzyme Q-10 Supportive 89 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
A Goal FitB+ Strength of SupportC- CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 directly supports mitochondrial energy production and antioxidant defense, which are central to cellular aging. The disclosed 100 mg ubiquinone serving provides a practical maintenance amount but requires conversion to the reduced form.

Human evidence is strongest for selected cardiovascular and energy-related uses rather than broad life-extension outcomes. The focused formula provides depth in one pathway but does not cover structural, inflammatory, or neurological needs comprehensively.

Study evidence
Coenzyme Q-10 Supportive 6 studies
Heart Health
Heart Health
Impact
Highest effect
B+ Goal FitB+ Strength of SupportC- CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 supports mitochondrial energy production in heart muscle and antioxidant defense. The ubiquinone form has useful human evidence, though it may absorb less efficiently than ubiquinol in some users.

The 100 mg amount is practical and fully disclosed in a focused softgel. The product delivers one cardiac-energy pathway well but does not address lipids, nitric oxide, or foundational minerals.

Study evidence
Coenzyme Q-10 Supportive 114 studies
Metabolism Boost
Metabolism Boost
Impact
High effect
B- Goal FitB+ Strength of SupportD CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 supports mitochondrial energy production through a direct cellular mechanism. The 100 mg amount is clearly disclosed, although evidence for increasing whole-body metabolic rate or fat loss is limited.

The ubiquinone formula is focused and provides useful depth for one energy pathway. It does not address thermogenesis, thyroid support, glycemic control, or fatty-acid transport.

Study evidence
Coenzyme Q-10 Disputed 11 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
B- Goal FitB Strength of SupportD- CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 supports mitochondrial energy production and antioxidant defense, which may help moderate oxidative triggers of inflammation. The 100 mg amount is a practical maintenance-level serving with the ubiquinone form clearly identified.

Support remains focused on oxidative and mitochondrial pathways rather than direct COX, LOX, or NF-kB modulation. Ubiquinone requires conversion to the reduced form, which may limit absorption for some users.

Study evidence
Coenzyme Q-10 Supportive 46 studies

Ingredients

IngredientAmount per serving
Coenzyme Q10 (Ubiquinone)
 100 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
Coenzyme Q-10 (Ubiquinone) · 100 mg OverallScore83
B Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyA+ Value

Ubiquinone is clearly identified, though it requires conversion to the reduced form. The clearly stated dose is suited to general maintenance. Its cost per active amount is highly competitive.

View ingredientView products
Loading alternative details
87 Performance

Mega CoQ10 Ubiquinol 100 mg

Qunol
The reduced ubiquinol form at 100 mg supports absorption and keeps the formula closely aligned with CoQ10 use. The provided quality and goal assessments are stronger than the original, although the ingredient list still does not provide independent testing or certification details.
87 Performance

Extra Strength Ubiquinol 200 mg

NOW
The reduced ubiquinol form at 200 mg supports absorption and keeps the formula closely aligned with CoQ10 use. The provided quality and goal assessments are stronger than the original, although the ingredient list still does not provide independent testing or certification details.
87 Performance

QH-absorb 100 mg

Jarrow Formulas
The reduced ubiquinol form at 100 mg supports absorption and keeps the formula closely aligned with CoQ10 use. The provided quality and goal assessments are stronger than the original, although the ingredient list still does not provide independent testing or certification details.
83 Budget

CoQ10 100 mg

Healthy Origins
A clearly stated ubiquinone dose at 100 mg provides a focused CoQ10 formula without unrelated active ingredients. Its lower serving cost improves routine value compared with the original; Ubiquinone is the oxidized form, so people specifically seeking ubiquinol may prefer another option.
85 Budget

High Absorption CoQ10 with BioPerine 100 mg

Doctor's Best
Ubiquinone at 100 mg is paired with black pepper extract to support absorption, adding a practical feature to a focused CoQ10 formula. Its lower serving cost improves routine value compared with the original; Black pepper extract can affect how some medicines are handled, so medication users should check suitability.
84 Budget

CoQ10 100 mg

California Gold Nutrition
A clearly stated ubiquinone dose at 100 mg provides a focused CoQ10 formula without unrelated active ingredients. Its lower serving cost improves routine value compared with the original; Ubiquinone is the oxidized form, so people specifically seeking ubiquinol may prefer another option.
85 Value

Mega Ubiquinol CoQ10 100 mg

Qunol
The reduced ubiquinol form at 100 mg supports absorption and keeps the formula closely aligned with CoQ10 use. Strong provided quality and goal assessments combine with favorable serving economics, improving the balance of formulation and value; the ingredient list still does not provide independent testing or certification details.
86 Value

Ubiquinol 100 mg

NOW
The reduced ubiquinol form at 100 mg supports absorption and keeps the formula closely aligned with CoQ10 use. Strong provided quality and goal assessments combine with favorable serving economics, improving the balance of formulation and value; the ingredient list still does not provide independent testing or certification details.
87 Value

CoQ10 200 mg

California Gold Nutrition
A clearly stated ubiquinone dose at 200 mg provides a focused CoQ10 formula without unrelated active ingredients. Strong provided quality and goal assessments combine with favorable serving economics, improving the balance of formulation and value; Ubiquinone is the oxidized form, so people specifically seeking ubiquinol may prefer another option.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  2. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  3. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  4. Coenzyme Q10 supplementation increases blood concentrations but shows limited and inconsistent effects on exercise performance: a systematic review and meta-analysis.
    Deng H; Song T; Yin M; Xu K; Zhong Y; Mohd NB; Naharudin MNB; Yusof A; Fan X · The British journal of nutrition · 2026
    Meta-analysis24 studies pooledEnergy forCoenzyme Q-10
  5. A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer.
    Lesser GJ; Case D; Stark N; Williford S; Giguere J; Garino LA; Naughton MJ; Vitolins MZ; Lively MO; Shaw EG; Wake Forest University Community Clinical Oncology Program Research Base · The journal of supportive oncology · 2013
    Randomized trial236 participantsEnergy forCoenzyme Q-10
  6. Platelet mitochondrial function and endogenous coenzyme Q10 levels are reduced in patients after COVID-19.
    Sumbalova Z; Kucharska J; Palacka P; Rausova Z; Langsjoen PH; Langsjoen AM; Gvozdjakova A · Bratislavske lekarske listy · 2022
    Cross-sectional study25 participantsEnergy forCoenzyme Q-10
  7. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  8. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  9. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  10. Supplementation with coenzyme Q10 reduces plasma lipoprotein(a) concentrations but not other lipid indices: A systematic review and meta-analysis.
    Sahebkar A; Simental-Mendía LE; Stefanutti C; Pirro M · Pharmacological research · 2016
    Meta-analysis409 participants7 studies pooledCardiovascular Support forCoenzyme Q-10
  11. Coenzyme Q10 for heart failure.
    Madmani ME; Yusuf Solaiman A; Tamr Agha K; Madmani Y; Shahrour Y; Essali A; Kadro W · The Cochrane database of systematic reviews · 2015
    Systematic review914 participants7 studies pooledCardiovascular Support forCoenzyme Q-10
  12. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  13. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewAnti-Aging forCoenzyme Q-10
  14. Coenzyme Q10 Supplementation in Aging and Disease.
    Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
    Narrative reviewAnti-Aging forCoenzyme Q-10
  15. Coenzyme Q10, a cutaneous antioxidant and energizer.
    Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
    Clinical trialAnti-Aging forCoenzyme Q-10
  16. Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
    Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
    Cross-sectional study4,260 participantsAnti-Aging forCoenzyme Q-10
  17. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsAnti-Aging forCoenzyme Q-10
  18. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  19. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  20. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  21. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  22. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  23. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  24. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  25. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  26. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  27. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  28. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Boost forCoenzyme Q-10
  29. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  30. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  31. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forCoenzyme Q-10
  32. Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
    Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
    Randomized trial100 participantsMetabolism Boost forCoenzyme Q-10
  33. The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
    Ahmadi Asouri S; Asemi R; Aghadavod E; Jamilian M · Annals of medicine and surgery (2012) · 2024
    Randomized trial40 participantsMetabolism Boost forCoenzyme Q-10