Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical trials.
Mendes ML; do Nascimento-Júnior EM; Reinheimer DM; Martins-Filho PR · Medicina oral, patologia oral y cirugia bucal · 2019
Meta-analysis6 studies pooledflagAnti-Inflammatory Support forscienceBromelain
- Urtica Dioica Root Extract on Clinical and Biochemical Parameters in Patients with Benign Prostatic Hyperplasia, Randomized Controlled Trial.
Akbar Karami A; Sheikhsoleimani M; Reza Memarzadeh M; Haddadi E; Bakhshpour M; Mohammadi N; Mehdi Mirhashemi S · Pakistan journal of biological sciences : PJBS · 2021
Randomized trial60 participantsflagAnti-Inflammatory Support forscienceStinging Nettle
- Is bromelain an effective drug for the control of pain and inflammation associated with impacted third molar surgery? Systematic review and meta-analysis.
de A C Almeida R; de Sousa Lima FCM; do E Vasconcelos BC · International journal of oral and maxillofacial surgery · 2019
Meta-analysis252 participants5 studies pooledflagAnti-Inflammatory Support forscienceBromelain
- [Recommendations of the DGRh Committee on Complementary Medicine and Nutrition on the application of selected phytotherapeutic drugs and herbal medicines in rheumatology].
Keyßer G; Seifert O; Frohne I; Michalsen A; Pfeil A; Reuß-Borst M; Sander O · Zeitschrift fur Rheumatologie · 2025
Guideline / consensusflagAnti-Inflammatory Support forscienceStinging Nettle
- Therapeutic efficacy of bromelain in impacted third molar surgery: a randomized controlled clinical study.
Ordesi P; Pisoni L; Nannei P; Macchi M; Borloni R; Siervo S · Quintessence international (Berlin, Germany : 1985) · 2016
Randomized trial80 participantsflagAnti-Inflammatory Support forscienceBromelain
- Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain.
Müller S; März R; Schmolz M; Drewelow B; Eschmann K; Meiser P · Phytotherapy research : PTR · 2013
Randomized trial12 participantsflagAnti-Inflammatory Support forscienceBromelain
- An Evaluation of the Effects of Pineapple-Extract and Bromelain-Based Treatment after Mandibular Third Molar Surgery: A Randomized Three-Arm Clinical Study.
Colletti A; Procchio C; Pisano M; Martelli A; Pellizzato M; Cravotto G · Nutrients · 2024
Randomized trial42 participantsflagAnti-Inflammatory Support forscienceBromelain
- Therapeutic uses of pineapple-extracted bromelain in surgical care - A review.
Muhammad ZA; Ahmad T · JPMA. The Journal of the Pakistan Medical Association · 2019
Narrative reviewflagAnti-Inflammatory Support forscienceBromelain
- The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trial.
Namazi N; Esfanjani AT; Heshmati J; Bahrami A · Pakistan journal of biological sciences : PJBS · 2012
Randomized trial50 participantsflagAnti-Inflammatory Support forscienceStinging Nettle
- Safety, Tolerability, and Efficacy of Hox Alpha, a Dry Extract from Stinging Nettle Leaves versus OTC NSAIDs in Osteoarthritis: A Retrospective, Propensity-Matched 12-Week Analysis from the German Pain e-Registry (SIPHARO Study).
Überall MA; Küster MA; Müller-Schwefe PCG; Müller-Schwefe GHH · Journal of pain research · 2026
Cohort study2,146 participantsflagAnti-Inflammatory Support forscienceStinging Nettle
- Randomized controlled trial of nettle sting for treatment of base-of-thumb pain
C Randall, H Randall, F Dobbs, C Hutton, H Sanders · Journal of the Royal Society of Medicine · 2000
Randomized trial27 participantsflagAnti-Inflammatory Support forscienceStinging Nettle
- Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
Randomized trial107 participantsflagAnti-Inflammatory Support forscienceVitamin C
- The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
Meta-analysis1,162 participants10 studies pooledflagAnti-Inflammatory Support forscienceVitamin C
- The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
Meta-analysis852 participants8 studies pooledflagAnti-Inflammatory Support forscienceVitamin C
- Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
Systematic review811 participants17 studies pooledflagAnti-Inflammatory Support forscienceVitamin C
- Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
Randomized trial44 participantsflagAnti-Inflammatory Support forscienceVitamin C
- Zinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agent.
Bao B; Prasad AS; Beck FW; Fitzgerald JT; Snell D; Bao GW; Singh T; Cardozo LJ · The American journal of clinical nutrition · 2010
Randomized trial40 participantsflagAnti-Inflammatory Support forscienceZinc
- Zinc Supplementation in Individuals with Prediabetes and type 2 Diabetes: a GRADE-Assessed Systematic Review and Dose-Response Meta-analysis.
Nazari M; Nikbaf-Shandiz M; Pashayee-Khamene F; Bagheri R; Goudarzi K; Hosseinnia NV; Dolatshahi S; Omran HS; Amirani N; Ashtary-Larky D; Asbaghi O; Ghanavati M · Biological trace element research · 2024
Meta-analysis23 studies pooledflagAnti-Inflammatory Support forscienceZinc
- The Effects of Zinc Supplementation on C-Reactive Protein and Inflammatory Cytokines: A Meta-Analysis and Systematical Review.
Ceylan MN; Akdas S; Yazihan N · Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2022
Meta-analysis73 studies pooledflagAnti-Inflammatory Support forscienceZinc
- The Effects of Zinc Sulfate Supplementation on Serum Copeptin, C-Reactive Protein and Metabolic Markers in Zinc-Deficient Diabetic Patients on Hemodialysis: A Randomized, Double-Blind, Placebo-Controlled Trial.
Hosseini R; Montazerifar F; Shahraki E; Karajibani M; Mokhtari AM; Dashipour AR; Ferns GA; Jalali M · Biological trace element research · 2021
Randomized trial46 participantsflagAnti-Inflammatory Support forscienceZinc
- Zinc supplementation and cardiovascular disease risk factors: A GRADE-assessed systematic review and dose-response meta-analysis.
Nazari M; Ashtary-Larky D; Nikbaf-Shandiz M; Goudarzi K; Bagheri R; Dolatshahi S; Omran HS; Amirani N; Ghanavati M; Asbaghi O · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2023
Meta-analysis75 studies pooledflagAnti-Inflammatory Support forscienceZinc
- The role of enzyme supplementation in digestive disorders.
Roxas M · Alternative medicine review : a journal of clinical therapeutic · 2009
Narrative reviewflagDigestive Health forscienceBromelain
- Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study.
Delgarm P; Mokhtare M; Ebrahimi Daryani N; Abolghasemi J; Rahideh ST · Scientific reports · 2025
Randomized trial70 participantsflagDigestive Health forscienceBromelain
- Oral zinc supplementation for the treatment of acute diarrhea in children: a systematic review and meta-analysis.
Lamberti LM; Walker CL; Chan KY; Jian WY; Black RE · Nutrients · 2014
Meta-analysis18,822 participants104 studies pooledflagDigestive Health forscienceZinc
- Zinc with oral rehydration therapy reduces stool output and duration of diarrhea in hospitalized children: a randomized controlled trial.
Bhatnagar S; Bahl R; Sharma PK; Kumar GT; Saxena SK; Bhan MK · Journal of pediatric gastroenterology and nutrition · 2004
Randomized trial287 participantsflagDigestive Health forscienceZinc
- Lower-Dose Zinc for Childhood Diarrhea - A Randomized, Multicenter Trial.
Dhingra U; Kisenge R; Sudfeld CR; Dhingra P; Somji S; Dutta A; Bakari M; Deb S; Devi P; Liu E; Chauhan A; Kumar J; Semwal OP; Aboud S; Bahl R; Ashorn P; Simon J; Duggan CP; Sazawal S; Manji K · The New England journal of medicine · 2020
Randomized trial4,500 participantsflagDigestive Health forscienceZinc
- Zinc supplementation in young children with acute diarrhea in India.
Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
Randomized trial937 participantsflagDigestive Health forscienceZinc
- Short-course prophylactic zinc supplementation for diarrhea morbidity in infants of 6 to 11 months.
Malik A; Taneja DK; Devasenapathy N; Rajeshwari K · Pediatrics · 2013
Randomized trial272 participantsflagDigestive Health forscienceZinc