Product Image

Ionic Selenium 300 mcg

Trace Minerals
4.8
★ ★ ★ ★ ★
(2850 ratings)
Chloride 60 mg
Selenium 300 mcg
Product Image
Score61
A simple but high-dose selenium liquid with limited trace-mineral transparency and little room for supplement stacking.
How scoring works
Quantity:2 Fluid Ounce(s) • (48 servings)
Goals:
Immunity
General Health

Score 61

A simple but high-dose selenium liquid with limited trace-mineral transparency and little room for supplement stacking.
How scoring works
$19.99($0.41 per serving)
iHerb
$ 19.99
Vitacost
$ 19.99
Vitacost
$ 19.99
Amazon
$ 19.99
Report prices

Analysis

The formula delivers 300 mcg selenium as sodium selenate, with magnesium and chloride from an ionic trace-mineral base. Its liquid form allows use without swallowing pills.

The selenium amount is high for a daily general-health or immunity product. A 350 mg trace-mineral entry is listed without a component breakdown, which limits evaluation of the rest of the formula.

Targeted users may value the clear selenium dose, but routine stacking can quickly produce excessive intake. Lower-dose options usually provide more margin for selenium already present in food and multivitamins.

Who is it for
  • Adults with a specific reason for higher-dose selenium
  • People who prefer liquid supplements
Best for
  • Targeted selenium intake
  • Tablet-free use

Pros

  • Clearly states selenium form and amount
  • Convenient liquid delivery
  • Includes supporting magnesium and chloride

Cons

  • Selenium amount is high
  • Trace-mineral blend lacks a breakdown
  • Poor fit for casual daily stacking

Warnings

  • The 300 mcg selenium serving leaves little room before the adult upper limit once food and other supplements are included.
  • Excess selenium can cause hair or nail changes, nausea, or a garlic-like breath odor.

Nutrient quality

60 Moderate impact

The selenium source is usable and the amount is substantial. A near-upper-limit dose and opaque trace-mineral base make the formula unnecessarily aggressive for routine general use.

.

Ingredient transparency

58 Moderate impact

Selenium and named supporting minerals have specific amounts. The ionic mineral material, directions, and inactive ingredients remain incompletely disclosed.

.

Customer satisfaction

72 High impact

The aggregate rating indicates very strong customer satisfaction. Substantial feedback volume supports the aggregate, but no review details are available.

.

Value for money

55 Moderate impact

The concentrated liquid is convenient, but the high selenium amount narrows practical usefulness. Clearer, lower-dose selenium products may offer safer routine value.

.
Report analysis

Goals

Immunity
Impact
High effect
A- Goal FitC- Strength of SupportD+ CoverageB+ Formula Quality
Magnesium · 20 mgSelenium · 300 mcg

Selenium directly supports antioxidant enzymes and helps regulate immune-related oxidative stress. The liquid provides a clearly stated but high selenium amount.

Sodium selenate is a less preferred inorganic form, and the ionic trace blend is not fully defined. The selenium amount leaves little room before the adult upper intake level once food and other supplements are included.

Study evidence
Selenium Mixed 37 studies
General Health
Impact
High effect
B+ Goal FitC- Strength of SupportC CoverageB Formula Quality
Magnesium · 20 mgSelenium · 300 mcg

Selenium provides focused support for antioxidant enzymes, thyroid hormone metabolism, and normal immune function. The liquid serving clearly discloses selenium as sodium selenate.

The 300 mcg amount is high relative to daily requirements and approaches the adult upper intake level. Regular use should avoid additional high-selenium supplements or unusually selenium-rich intake.

Study evidence
Magnesium Supportive 114 studies
Selenium Supportive 70 studies

Ingredients

IngredientAmount per serving
Magnesium (Ionic Trace Minerals)
20 mg
Selenium (Sodium Selenate)
300 mcg
Chloride (Ionic Trace Minerals)
60 mg
Ionic Trace Minerals
350 mg
Gluten Free Adults 18–50 Vegan No Allergies Vegetarian
Report overview
A+ Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyB+ Value

Ionic trace minerals provide chloride in a concentrated mineral complex. The chloride serving is below the collection median and contributes little to electrolyte replenishment. The cost per serving is good, although the chloride contribution is modest.

F Active Ingredient Quality & BioavailabilityD Dose, Safety & Label TransparencyC Value
Sodium selenate is clearly identified but offers lower cellular retention than preferred organic forms. The dose is effective but leaves a narrow margin below the daily upper limit, so other selenium sources matter. Cost efficiency is moderate for the standardized selenium amount. Value from the broader standalone liquid may still matter beyond selenium alone.
Loading alternative details
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Selenium intake and multiple health-related outcomes: an umbrella review of meta-analyses.
    Wang P; Chen B; Huang Y; Li J; Cao D; Chen Z; Li J; Ran B; Yang J; Wang R; Wei Q; Dong Q; Liu L · Frontiers in nutrition · 2024
    Systematic reviewGeneral Health forSelenium
  2. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  3. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  4. Selenium supplementation for the primary prevention of cardiovascular disease.
    Rees K; Hartley L; Day C; Flowers N; Clarke A; Stranges S · The Cochrane database of systematic reviews · 2013
    Meta-analysis19,715 participants12 studies pooledGeneral Health forSelenium
  5. Effect of long-term selenium supplementation on mortality: Results from a multiple-dose, randomised controlled trial.
    Rayman MP; Winther KH; Pastor-Barriuso R; Cold F; Thvilum M; Stranges S; Guallar E; Cold S · Free radical biology & medicine · 2019
    Randomized trial491 participantsGeneral Health forSelenium
  6. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  7. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  8. Selenium supplementation has beneficial and detrimental effects on immunity to influenza vaccine in older adults.
    Ivory K; Prieto E; Spinks C; Armah CN; Goldson AJ; Dainty JR; Nicoletti C · Clinical nutrition (Edinburgh, Scotland) · 2018
    Randomized trial117 participantsImmunity forSelenium
  9. Selenium and immune function: a systematic review and meta-analysis of experimental human studies.
    Filippini T; Fairweather-Tait S; Vinceti M · The American journal of clinical nutrition · 2023
    Meta-analysis9 studies pooledImmunity forSelenium
  10. Effect of low-dose selenium on thyroid autoimmunity and thyroid function in UK pregnant women with mild-to-moderate iodine deficiency.
    Mao J; Pop VJ; Bath SC; Vader HL; Redman CW; Rayman MP · European journal of nutrition · 2016
    Randomized trial230 participantsImmunity forSelenium
  11. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  12. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  13. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  14. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  15. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  16. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health forSelenium
  17. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  18. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  19. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  20. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  21. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium