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Sugar Control

NaturesPlus
4.7
★ ★ ★ ★ ★
(150 ratings)
Chromium 200 mcg
Alanine 75 mg
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Score75

A chromium-led glucose-support capsule with a modest botanical addition. Small amino-acid amounts and weak direct weight-loss relevance limit breadth.

How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
Metabolism Boost
Weight Loss

Score 75

A chromium-led glucose-support capsule with a modest botanical addition. Small amino-acid amounts and weak direct weight-loss relevance limit breadth.

How scoring works
$19.93($0.33 per serving)
iHerb
$ 19.93
iHerb
$ 19.93
Pure Formulas
$ 19.93
Vitacost
$ 19.93
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Analysis

The capsule provides 200 mcg chromium from branded ChromeMate with 200 mg Rehmannia glutinosa. Chromium is the clearest active for normal glucose metabolism.

Glutamine at 100 mg and alanine at 75 mg are too small to anchor amino-acid support. Rehmannia is not standardized in the supplied data, making its potency difficult to assess.

The formula may suit adults seeking a compact chromium supplement with a botanical addition. It should not be treated as a direct weight-loss product, and medication interactions matter for users managing blood glucose.

Who is it for
  • Adults seeking branded chromium
  • People focused on glucose-metabolism support
  • Users not taking glucose-lowering medication without guidance
Best for
  • Chromium supplementation
  • Glucose-metabolism support
  • Simple one-capsule use

Pros

  • Uses branded ChromeMate chromium
  • Provides a clear 200 mcg chromium amount
  • One-capsule serving
  • Includes Rehmannia

Cons

  • Rehmannia is not standardized
  • Glutamine amount is token
  • Alanine amount is small
  • Limited direct weight-loss support

Warnings

  • Chromium may amplify the effects of insulin or sulfonylurea medicines
  • People using glucose-lowering medication should monitor for low blood sugar with their prescriber
  • Stop use and seek advice for symptoms of low blood sugar
  • Rehmannia interaction and sensitivity screening is limited by the supplied form detail

Nutrient quality

75 High impact

Branded chromium polynicotinate is a strong form at a meaningful amount. Unstandardized rehmannia and very small amino acid amounts limit the broader metabolic strategy.

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Ingredient transparency

81 Highest impact

Active ingredient amounts and the serving count are clear from the supplied facts. Complete directions, non-active ingredients, and some source details are missing.

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Customer satisfaction

69 High impact

The aggregate rating is strong and supported by a moderate feedback volume. Specific experience details are missing, so recurring problems and purpose fit remain uncertain.

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Value for money

72 High impact

The high-quality chromium form supports fair value, though secondary ingredients are weak. Serving value is reasonable for focused glucose support.

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Goals

Metabolism Boost
Metabolism Boost
Impact
High effect
B Goal FitB+ Strength of SupportC- CoverageB- Formula Quality

Branded chromium provides a meaningful, directly relevant approach to insulin signaling and carbohydrate use. The formula is more suited to glycemic support than to increasing energy expenditure.

Rehmannia lacks standardization, and the small amino acid amounts are unlikely to add much metabolic effect. Chromium may amplify glucose-lowering medicines, so people using insulin or sulfonylureas should monitor for low blood sugar with clinical guidance.

Study evidence
Chromium Supportive 47 studies
Weight Loss
Weight Loss
Impact
Moderate effect
F Goal FitC+ Strength of SupportF CoverageC Formula Quality

Chromium may support steadier glucose handling and cravings, but the formula does not directly address thermogenesis or satiety. The added amino acids and rehmannia have limited value for preserving muscle or driving weight loss at these amounts.

The clearly listed doses make the formula easy to assess, though evidence for meaningful body-composition change is modest. Chromium can affect blood sugar, so people using insulin or glucose-lowering medicines should monitor for low blood sugar with their prescriber.

Study evidence
Chromium No effect 24 studies

Ingredients

IngredientAmount per serving
Chromium (ChromeMate)
 200 mcg
Rehmannia glutinosa
200 mg
L-Glutamine
100 mg
L-Alanine
75 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
Chromium (ChromeMate) · 200 mcg OverallScore89
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB Value

Chromium polynicotinate is a highly bioavailable organic form. The 200 mcg elemental chromium serving falls in the preferred potency range. The cost per standard chromium amount is in the good-value range.

View ingredientView products
Alanine · 75 mg OverallScore65
B+ Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyD+ Value

The clearly named L-Alanine and disclosed dose make the formula easy to assess. The amount sits at the low end of the collection and may provide only modest alanine support. Its relatively low serving cost partly offsets the limited dose.

View ingredientView products
Loading alternative details
88 Performance

Chromium Picolinate

Swanson
<p>A more useful ingredient profile provides 200 mcg of Chromax chromium picolinate. Compared with the original 200 mcg of ChromeMate chromium with alanine, glutamine, and rehmannia, it matches the original chromium amount with stronger chromium and metabolism alignment, but is only a chromium substitute rather than a full formula match.</p>
86 Performance

Optimized Chromium with Crominex 3+ 500 mcg

Life Extension
<p>A more useful ingredient profile provides 500 mcg of Crominex 3+ chromium. Compared with the original 200 mcg of ChromeMate chromium with alanine, glutamine, and rehmannia, it provides a clearly named chromium form with stronger chromium alignment, though the higher dose and missing alanine make it a narrower option.</p>
84 Performance

Chromium Picolinate 500 mcg

Natural Factors
<p>A more useful ingredient profile provides 500 mcg of chromium picolinate. Compared with the original 200 mcg of ChromeMate chromium with alanine, glutamine, and rehmannia, it uses a straightforward, disclosed chromium form with better chromium alignment, but does not cover the original amino acids or rehmannia.</p>
88 Budget

Albion Chelated Chromium 200 mcg

Swanson Ultra
<p>A lower serving cost still provides 200 mcg of TRAACS chromium nicotinate glycinate chelate. Compared with the original 200 mcg of ChromeMate chromium with alanine, glutamine, and rehmannia, it matches the original chromium amount in a clearly identified chelated form, but omits alanine, glutamine, rehmannia, and the broader blend.</p>
83 Budget

Tri-Chromium 500 mcg

NOW
<p>A lower serving cost still provides 500 mcg of chromium across ChromeMate, Chelavite, and picolinate forms plus 250 mg of cinnamon. Compared with the original 200 mcg of ChromeMate chromium with alanine, glutamine, and rehmannia, it broadens chromium forms and adds cinnamon at lower cost, though the dose is higher and alanine is absent.</p>
83 Budget

Chromemate Chromium GTF 200 mcg

Source Naturals
<p>A lower serving cost still provides 200 mcg of chromium polynicotinate with listed niacin. Compared with the original 200 mcg of ChromeMate chromium with alanine, glutamine, and rehmannia, it matches the original chromium amount in a focused ChromeMate-style form, but does not replace alanine, glutamine, or rehmannia.</p>
87 Value

Chelated Chromium 200 mcg

Carlson
<p>A favorable balance of quality and cost provides 200 mcg of chromium nicotinate glycinate chelate with 26 mg of calcium. Compared with the original 200 mcg of ChromeMate chromium with alanine, glutamine, and rehmannia, it matches the original chromium amount in a chelated form and offers strong value, while omitting alanine and the other original ingredients.</p>
86 Value

Chromium Picolinate 200 mcg

Solgar
<p>A favorable balance of quality and cost provides 200 mcg of chromium picolinate. Compared with the original 200 mcg of ChromeMate chromium with alanine, glutamine, and rehmannia, it matches the original chromium amount in a simple formula at lower cost, but cannot replace the original alanine, glutamine, or botanical component.</p>
83 Value

Chromium Picolinate 200 mcg

Best Naturals
<p>A favorable balance of quality and cost provides 200 mcg of chromium picolinate. Compared with the original 200 mcg of ChromeMate chromium with alanine, glutamine, and rehmannia, it provides the same chromium amount with a clearly named form and low serving cost, though the formula is much narrower.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Improved meta-analytic methods show no effect of chromium supplements on fasting glucose.
    Bailey CH · Biological trace element research · 2014
    Meta-analysis809 participants16 studies pooledMetabolism Boost forChromium
  2. A pilot study of chromium picolinate for weight loss.
    Yazaki Y; Faridi Z; Ma Y; Ali A; Northrup V; Njike VY; Liberti L; Katz DL · Journal of alternative and complementary medicine (New York, N.Y.) · 2010
    Randomized trial80 participantsWeight Loss forChromium
  3. Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity.
    Masharani U; Gjerde C; McCoy S; Maddux BA; Hessler D; Goldfine ID; Youngren JF · BMC endocrine disorders · 2013
    Randomized trial31 participantsMetabolism Boost forChromium
  4. Chromium picolinate balances the metabolic and clinical markers in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial.
    Kooshki F; Moradi F; Karimi A; Niazkar HR; Khoshbaten M; Maleki V; Pourghassem Gargari B · European journal of gastroenterology & hepatology · 2021
    Randomized trial46 participantsWeight Loss forChromium
  5. The Effects of Supplementation with Chromium on Insulin Resistance Indices in Women with Polycystic Ovarian Syndrome: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Heshmati J; Omani-Samani R; Vesali S; Maroufizadeh S; Rezaeinejad M; Razavi M; Sepidarkish M · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2018
    Meta-analysis268 participants5 studies pooledMetabolism Boost forChromium
  6. Association Between Essential and Non-essential Metals, Body Composition, and Metabolic Syndrome in Adults.
    Ngu YJ; Skalny AV; Tinkov AA; Tsai CS; Chang CC; Chuang YK; Nikolenko VN; Zotkin DA; Chiu CF; Chang JS · Biological trace element research · 2022
    Cross-sectional study150 participantsWeight Loss forChromium
  7. Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes.
    Anderson RA; Cheng N; Bryden NA; Polansky MM; Cheng N; Chi J; Feng J · Diabetes · 1997
    Randomized trial180 participantsMetabolism Boost forChromium
  8. The Influences of Chromium Supplementation on Metabolic Status in Patients with Type 2 Diabetes Mellitus and Coronary Heart Disease.
    Farrokhian A; Mahmoodian M; Bahmani F; Amirani E; Shafabakhsh R; Asemi Z · Biological trace element research · 2021
    Randomized trial64 participantsWeight Loss forChromium
  9. Chromium effects on glucose tolerance and insulin sensitivity in persons at risk for diabetes mellitus.
    Ali A; Ma Y; Reynolds J; Wise JP; Inzucchi SE; Katz DL · Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2011
    Randomized trial59 participantsMetabolism Boost forChromium
  10. Chromium picolinate supplementation in women: effects on body weight, composition, and iron status.
    Lukaski HC; Siders WA; Penland JG · Nutrition (Burbank, Los Angeles County, Calif.) · 2007
    Randomized trial83 participantsWeight Loss forChromium
  11. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes.
    Martin J; Wang ZQ; Zhang XH; Wachtel D; Volaufova J; Matthews DE; Cefalu WT · Diabetes care · 2006
    Randomized trial37 participantsMetabolism Boost Weight Loss forChromium
  12. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forChromium
  13. Chromium picolinate reduces insulin resistance in polycystic ovary syndrome: Randomized controlled trial.
    Ashoush S; Abou-Gamrah A; Bayoumy H; Othman N · The journal of obstetrics and gynaecology research · 2017
    Randomized trial100 participantsWeight Loss forChromium
  14. [Chromium supplementation in patients with type 2 diabetes and high risk of type 2 diabetes: a meta-analysis of randomized controlled trials].
    San Mauro-Martin I; Ruiz-León AM; Camina-Martín MA; Garicano-Vilar E; Collado-Yurrita L; Mateo-Silleras Bd; Redondo Del Río Mde P · Nutricion hospitalaria · 2017
    Meta-analysis13 studies pooledMetabolism Boost forChromium
  15. Chromium picolinate does not improve key features of metabolic syndrome in obese nondiabetic adults.
    Iqbal N; Cardillo S; Volger S; Bloedon LT; Anderson RA; Boston R; Szapary PO · Metabolic syndrome and related disorders · 2009
    Randomized trial63 participantsMetabolism Boost Weight Loss forChromium
  16. Systematic review and meta-analysis of the efficacy and safety of chromium supplementation in diabetes.
    Suksomboon N; Poolsup N; Yuwanakorn A · Journal of clinical pharmacy and therapeutics · 2015
    Meta-analysis25 studies pooledMetabolism Boost forChromium
  17. Effect of chromium supplementation on the glucose homeostasis and anthropometry of type 2 diabetic patients: Double blind, randomized clinical trial: Chromium, glucose homeostasis and anthropometry.
    Guimarães MM; Carvalho AC; Silva MS · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2017
    Randomized trial56 participantsWeight Loss forChromium
  18. Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial.
    Kleefstra N; Houweling ST; Jansman FG; Groenier KH; Gans RO; Meyboom-de Jong B; Bakker SJ; Bilo HJ · Diabetes care · 2006
    Randomized trial46 participantsWeight Loss forChromium
  19. Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Jamilian M; Asemi Z · Annals of nutrition & metabolism · 2016
    Randomized trial64 participantsMetabolism Boost forChromium
  20. A Comprehensive insight into the effect of chromium supplementation on oxidative stress indices in diabetes mellitus: A systematic review.
    Kooshki F; Tutunchi H; Vajdi M; Karimi A; Niazkar HR; Shoorei H; Pourghassem Gargari B · Clinical and experimental pharmacology & physiology · 2024
    Systematic review33 studies pooledMetabolism Boost forChromium
  21. Chromium supplementation and polycystic ovary syndrome: A systematic review and meta-analysis.
    Fazelian S; Rouhani MH; Bank SS; Amani R · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2018
    Meta-analysis351 participants7 studies pooledWeight Loss forChromium