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Super Quercetin

Bluebonnet
4.8
★ ★ ★ ★ ★
(898 ratings)
Vitamin C 500 mg
Bromelain 140 mg
Rutin 20 mg
Acerola 25 mg
Product Image
Score77
A convenient larger supply of quercetin and vitamin C, with modest value gains but the same uncertainty around bromelain potency.
How scoring works
Quantity:90 Capsule(s) • (45 servings)
Goals:
Immunity
General Health
Anti-Inflammatory Support
Skin Health

Score 77

A convenient larger supply of quercetin and vitamin C, with modest value gains but the same uncertainty around bromelain potency.
How scoring works
$46.00($1.02 per serving)
iHerb
$ 46.00
Daily Vita
$ 46.00
Vitacost
$ 46.00
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Analysis

Quercetin and L-ascorbic acid provide the main functional value at equal, substantial amounts. Bromelain and citrus bioflavonoids offer a reasonable complementary design for antioxidant and immune-focused use.

Missing enzyme activity makes the bromelain difficult to compare with purpose-built enzyme supplements. Small amounts of acerola, rose hips, and rutin broaden the label more than the likely effect.

The larger count lowers serving cost slightly and reduces the need to reorder frequently. It is still best judged as a quercetin-and-vitamin C product rather than a comprehensive botanical blend.

Who is it for
  • Regular quercetin users
  • Adults seeking a larger supply of antioxidant support
Best for
  • Longer-term quercetin and vitamin C use
  • Fewer repeat purchases

Pros

  • Meaningful quercetin amount
  • Meaningful vitamin C amount
  • Largest package of the three variants

Cons

  • Bromelain activity is not disclosed
  • Acerola and rutin are minimally dosed
  • Unbuffered vitamin C may be less comfortable

Warnings

  • Bromelain may increase bleeding tendency with anticoagulant or antiplatelet medicines.
  • L-ascorbic acid may cause stomach discomfort in sensitive users.

Nutrient quality

84 Highest impact

Quercetin, vitamin C, and bromelain are supplied at useful amounts and fit the intended support. Plain quercetin and several token-sized companions keep the formula from standing out.

Ingredient transparency

83 Highest impact

Every active has a stated amount and no proprietary blend obscures the formula. Some extract specifications, non-active ingredients, and complete use directions are absent.

Customer satisfaction

71 High impact

The average rating is excellent, with a large review count supporting the signal. No detailed reviews are supplied to assess recurring complaints or experiences tied to the intended use.

Value for money

67 High impact

The main actives are meaningfully supplied in a focused combination. The longer supply improves value, though the plain quercetin form remains ordinary.

Report analysis

Goals

Immunity
Impact
Highest effect
A Goal FitB+ Strength of SupportB+ CoverageA- Formula Quality
Vitamin C · 500 mg

Vitamin C and quercetin provide substantial antioxidant and immune-cell support. Bromelain and citrus flavonoids broaden the formula toward inflammatory and upper-airway comfort pathways.

The main actives have useful amounts, but bromelain activity units and botanical standardization are not disclosed. Bromelain may increase bleeding risk when used with anticoagulant or antiplatelet medicines.

Study evidence
Bromelain Not classified 1 study
Vitamin C Supportive 53 studies
General Health
Impact
Highest effect
B+ Goal FitB+ Strength of SupportB CoverageA Formula Quality
Vitamin C · 500 mg

Vitamin C, quercetin, bromelain, and citrus bioflavonoids create a coherent antioxidant-focused formula. The vitamin C and quercetin amounts are substantial, while bromelain adds a situational enzyme pathway rather than broad foundational nutrition.

Exact ingredient amounts are stated, but bromelain activity units and its botanical source are missing, so enzyme potency cannot be confirmed. Bromelain may increase bleeding tendency when combined with anticoagulant or antiplatelet medicines.

Study evidence
Bromelain Supportive 11 studies
Vitamin C Supportive 56 studies
Impact
High effect
B+ Goal FitC+ Strength of SupportB+ CoverageA- Formula Quality
Vitamin C · 500 mg

Quercetin, bromelain, vitamin C, rutin, and citrus flavonoids target complementary inflammatory and antioxidant pathways. Quercetin and bromelain have relevant mechanistic and human support, though enzyme potency depends on missing activity units.

Quercetin and vitamin C are materially supplied, while bromelain is meaningful by mass and rutin is modest. Bromelain may increase bleeding risk when combined with anticoagulant or antiplatelet medicines.

Study evidence
Bromelain Supportive 12 studies
Rutin Supportive 6 studies
Vitamin C Supportive 50 studies
Skin Health
Impact
High effect
C+ Goal FitB Strength of SupportC+ CoverageB+ Formula Quality
Vitamin C · 500 mg

Vitamin C supports collagen production, while quercetin and citrus flavonoids broaden antioxidant defense. Both main actives are clearly disclosed at substantial amounts.

The formula does not supply collagen peptides, ceramides, or a direct hydration ingredient. Plain ascorbic acid and generic quercetin also lack an absorption-focused delivery system.

Study evidence
Vitamin C Supportive 53 studies
Impact
Moderate effect
F Goal FitC+ Strength of SupportD- CoverageB Formula Quality
Vitamin C · 500 mg

Vitamin C, quercetin, and flavonoids provide substantial general antioxidant support but little direct macular protection. The formula lacks lutein, zeaxanthin, DHA, zinc, and copper.

All amounts are disclosed, though the flavonoids are not standardized and plain ascorbic acid offers no delivery advantage. Its strongest rationale is broad antioxidant support rather than a targeted vision effect.

Study evidence
Rutin Not classified 1 study
Vitamin C Disputed 24 studies

Ingredients

IngredientAmount per serving
Vitamin C (L-Ascorbic Acid)
500 mg
Quercetin
500 mg
Bromelain
140 mg
Citrus Bioflavonoid Complex
100 mg
Acerola
25 mg
Rose Hips
25 mg
Rutin
20 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free No Allergies Vegetarian
Report overview
F Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value

The 500 mg vitamin C serving is useful and accompanies substantial quercetin plus supporting flavonoids. Plain L-ascorbic acid offers no buffering or enhanced-delivery feature. The formula may appeal for its broader blend, but its vitamin C is expensive per gram.

Bromelain · 140 mg OverallScore37
F Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyF Value

The multi-ingredient formula supplies a meaningful bromelain amount alongside quercetin, but no enzyme activity units are given to confirm potency. A standard vegetable capsule is reasonable for systemic use, though the botanical source and timing directions are missing. The bromelain dose may add bleeding risk when combined with anticoagulant or antiplatelet drugs.

Rutin · 20 mg OverallScore30
F Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyF Value

Rutin has a clear standalone amount, but its source and purity remain unspecified. The amount is too low for targeted capillary support and functions mainly as a minor addition to the broader formula. Even with the largest bottle size, cost per unit of rutin remains very high.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study.
    Delgarm P; Mokhtare M; Ebrahimi Daryani N; Abolghasemi J; Rahideh ST · Scientific reports · 2025
    Randomized trial70 participantsGeneral Health forBromelain
  2. Bromelain as an adjunctive treatment for moderate-to-severe osteoarthritis of the knee: a randomized placebo-controlled pilot study.
    Brien S; Lewith G; Walker AF; Middleton R; Prescott P; Bundy R · QJM : monthly journal of the Association of Physicians · 2007
    Randomized trial47 participantsGeneral Health forBromelain
  3. Perioperative bromelain reduces pain and swelling and improves quality of life measures after mandibular third molar surgery: a randomized, double-blind, placebo-controlled clinical trial.
    Majid OW; Al-Mashhadani BA · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons · 2014
    Randomized trial45 participantsGeneral Health forBromelain
  4. Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical trials.
    Mendes ML; do Nascimento-Júnior EM; Reinheimer DM; Martins-Filho PR · Medicina oral, patologia oral y cirugia bucal · 2019
    Meta-analysis6 studies pooledGeneral Health Anti-Inflammatory Support forBromelain
  5. Bromelain-based enzymatic burn debridement: A systematic review of clinical studies on patient safety, efficacy and long-term outcomes.
    Shoham Y; Gasteratos K; Singer AJ; Krieger Y; Silberstein E; Goverman J · International wound journal · 2023
    Systematic review34 studies pooledGeneral Health forBromelain
  6. Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain.
    Müller S; März R; Schmolz M; Drewelow B; Eschmann K; Meiser P · Phytotherapy research : PTR · 2013
    Randomized trial12 participantsGeneral Health Anti-Inflammatory Support Immunity forBromelain
  7. Comparison of Bromelain and Diclofenac in the Management of Postoperative Pain and Quality of Life Following Root Canal Therapy: A Randomized Controlled Trial.
    Sherin A; Anirudhan S; Koshy M · Cureus · 2024
    Randomized trial100 participantsGeneral Health forBromelain
  8. Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adults.
    Walker AF; Bundy R; Hicks SM; Middleton RW · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2003
    Randomized trial77 participantsGeneral Health forBromelain
  9. Bromelain has significant clinical benefits after extraction of the third molar during chemotherapy in patients with hematologic tumor.
    Tan Y; Li P · Oncology letters · 2022
    Clinical trial72 participantsGeneral Health forBromelain
  10. The Clinical Efficacy of Pollen Extract and Vitamins on Chronic Prostatitis/Chronic Pelvic Pain Syndrome Is Linked to a Decrease in the Pro-Inflammatory Cytokine Interleukin-8.
    Cai T; Verze P; La Rocca R; Palmieri A; Tiscione D; Luciani LG; Mazzoli S; Mirone V; Malossini G · The world journal of men's health · 2020
    Randomized trial65 participantsGeneral Health forBromelain
  11. Therapeutic efficacy of bromelain in impacted third molar surgery: a randomized controlled clinical study.
    Ordesi P; Pisoni L; Nannei P; Macchi M; Borloni R; Siervo S · Quintessence international (Berlin, Germany : 1985) · 2016
    Randomized trial80 participantsAnti-Inflammatory Support forBromelain
  12. An Evaluation of the Effects of Pineapple-Extract and Bromelain-Based Treatment after Mandibular Third Molar Surgery: A Randomized Three-Arm Clinical Study.
    Colletti A; Procchio C; Pisano M; Martelli A; Pellizzato M; Cravotto G · Nutrients · 2024
    Randomized trial42 participantsAnti-Inflammatory Support forBromelain
  13. Therapeutic uses of pineapple-extracted bromelain in surgical care - A review.
    Muhammad ZA; Ahmad T · JPMA. The Journal of the Pakistan Medical Association · 2019
    Narrative reviewAnti-Inflammatory Support forBromelain
  14. The effects of rutin flavonoid supplement on glycemic status, lipid profile, atherogenic index of plasma, brain-derived neurotrophic factor (BDNF), some serum inflammatory, and oxidative stress factors in patients with type 2 diabetes mellitus: A double-blind, placebo-controlled trial.
    Bazyar H; Moradi L; Zaman F; Zare Javid A · Phytotherapy research : PTR · 2023
    Randomized trial50 participantsAnti-Inflammatory Support forRutin
  15. Rutin ameliorates inflammation and improves metabolic function: A comprehensive analysis of scientific literature.
    Muvhulawa N; Dludla PV; Ziqubu K; Mthembu SXH; Mthiyane F; Nkambule BB; Mazibuko-Mbeje SE · Pharmacological research · 2022
    Systematic reviewAnti-Inflammatory Support forRutin
  16. Rutin-loaded chitosan microspheres: Characterization and evaluation of the anti-inflammatory activity.
    Cosco D; Failla P; Costa N; Pullano S; Fiorillo A; Mollace V; Fresta M; Paolino D · Carbohydrate polymers · 2018
    OtherAnti-Inflammatory Support forRutin
  17. Oral enzyme combination therapy reduces systemic inflammation, urinary CTXII and pain in knee osteoarthritis: a proof-of-mechanism, randomised, crossover, double-blind, placebo-controlled trial.
    Henrotin Y; Pap T; Lieten S; Badot V; Dubuc JE; Urbin-Choffray D; von Eynatten M; Johansen OE; Rau S; Brabants K · RMD open · 2025
    Randomized trial45 participantsAnti-Inflammatory Support forRutin
  18. The Impact of the Combination of Proteolytic Enzyme and Rutin on the Post-operative Management of Inflammation: A Randomized, Controlled, Double-Blind, Comparative Clinical Trial
    Rathi PC, Rathi CL, Risbud SP, Ganu GP · Cureus · 2024
    Randomized trial65 participantsAnti-Inflammatory Support forRutin
  19. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  20. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  21. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  22. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  23. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  24. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  25. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  26. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  27. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  28. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  29. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  30. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  31. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  32. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  33. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  34. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  35. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  36. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  37. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  38. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  39. A randomized, double-masked study on the treatment of retinal vein occlusion with troxerutin
    Glacet-Bernard A, Coscas G, Chabanel A, Zourdani A, Lelong F, Samama MM · American Journal of Ophthalmology · 1994
    Randomized trial53 participantsVision Support forRutin
  40. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  41. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  42. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  43. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C
  44. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C