Product Image

Inflamma-Less

Irwin Naturals
4.4
★ ★ ★ ★ ★
(1159 ratings)
Papain 100 mg
Boswellia 200 mg
Turmeric 200 mg
Resveratrol 10 mg
Ginger
Fish Oil 1176 mg
Product Image
Score54
A broad inflammation-oriented blend covers several useful pathways. Opaque active yields and enzyme potency make the label far less informative than the ingredient list.
How scoring works
Quantity:80 Softgel(s) • (40 servings)
Goals:
Anti-Inflammatory Support
Digestive Health

Score 54

A broad inflammation-oriented blend covers several useful pathways. Opaque active yields and enzyme potency make the label far less informative than the ingredient list.
How scoring works
$27.45($0.68 per serving)
iHerb
$ 27.99
Pure Formulas
$ 27.99
Amazon
$ 27.45
Vitacost
$ 29.65
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Analysis

The formula combines lipid, botanical, antioxidant, and enzyme pathways rather than relying on one ingredient. Boswellia, turmeric, quercetin, papain, fish oil, and vitamin C are all relevant to a broad inflammation-support strategy.

EPA and DHA are not disclosed, while curcuminoid and boswellic-acid yields are also missing. Papain reaches a meaningful weight, but activity units are absent, and several other enzymes have no usable dose information.

Black pepper and the lipid softgel may improve absorption of some plant extracts. The crowded design may appeal to users wanting breadth, but a focused formula with standardized actives would be easier to assess and combine safely.

Who is it for
  • Adults seeking broad multi-pathway inflammatory support
  • Users comfortable with fish oil and multiple botanicals
  • People who can review medication interactions
Best for
  • Broad botanical and omega-3 routines
  • Users wanting papain with plant extracts
  • People who value absorption-support ingredients

Pros

  • Combines several directly relevant ingredients
  • Papain weight is clearly stated
  • Oil base and black pepper may support absorption

Cons

  • EPA and DHA are undisclosed
  • Curcuminoid and boswellic-acid yields are missing
  • Most enzyme activity units are unavailable

Warnings

  • Fish oil, turmeric, Boswellia, and papain may add to bleeding risk with anticoagulant or antiplatelet medicines.
  • Papain can trigger reactions in people with papaya or latex allergy.
  • Fish oil makes the product unsuitable for people with a fish allergy.
  • BioPerine may change absorption of some medicines, so users with complex drug regimens should check compatibility.

Nutrient quality

61 Moderate impact

The formula covers several relevant inflammatory and digestive pathways in an oil-based softgel. Missing omega-three amounts, enzyme activities, and botanical standardization make the crowded blend difficult to dose or balance confidently.

Ingredient transparency

42 Lower impact

Some totals are stated, but EPA, DHA, enzyme activities, and multiple botanical marker entries have no usable amounts. Complete directions, source details, and softgel excipients are also absent.

Customer satisfaction

66 High impact

The fair average rating and large review count make the aggregate satisfaction signal reasonably dependable. No detailed review text was provided, so recurring complaints and purpose alignment cannot be assessed.

Value for money

51 Moderate impact

Broad pathway coverage provides some value at a moderate serving cost. Major dose gaps and numerous token additions make focused, fully disclosed alternatives more competitive.

Report analysis

Goals

Anti-Inflammatory Support
Impact
Moderate effect
B- Goal FitD+ Strength of SupportC+ CoverageC Formula Quality
Fish Oil · 1176 mgVitamin C · 100 mgBoswellia · 200 mg

Fish oil, boswellia, turmeric, quercetin, papain, and vitamin C create a directly relevant anti-inflammatory formula. EPA and DHA are not disclosed, while boswellic acid and curcuminoid percentages are missing.

The lipid softgel and black pepper may aid botanical absorption, but several supporting ingredients are token additions. Fish oil, turmeric, boswellia, and papain may increase bleeding risk with anticoagulant or antiplatelet medicines.

Study evidence
Boswellia Supportive 19 studies
Fish Oil Supportive 68 studies
Ginger Supportive 30 studies
Papain Not classified

No linked studies yet.

Resveratrol Supportive 34 studies
Vitamin C Supportive 50 studies
Digestive Health
Impact
Moderate effect
C- Goal FitD- Strength of SupportC- CoverageD Formula Quality
Zinc · 2 mgPapain · 100 mgBromelain · NPBoswellia · 200 mg

Papain and several other enzymes provide plausible protein-digestion support, while turmeric and Boswellia add an inflammatory-balance pathway. The liquid softgel may improve absorption of the botanical extracts.

Missing enzyme activity units and undisclosed enzyme amounts make the digestive effect uncertain. Papain may trigger a reaction in people with papaya or latex allergy.

Study evidence
Boswellia Supportive 9 studies
Bromelain Supportive 2 studies
Ginger Supportive 31 studies
Papain Adverse 2 studies

Ingredients

IngredientAmount per serving
Calories
20 Calorie(s)
Total Fat
1 Gram(s)
Cholesterol
5 mg
Total Carbohydrates
1 Gram(s)
Protein
1 Gram(s)
Vitamin C
100 mg
Zinc
2 mg
Fish Oil
1176 mg
Indian Frankincense extract
200 mg
Turmeric extract
200 mg
Hesperidin Complex
110 mg
Quercetin
100 mg
Ginger extract
10 mg
Resveratrol
10 mg
Bromelain
0 NP
Chymotrypsin
0 NP
Pancreatin
0 NP
Papain
100 mg
Trypsin
0 NP
BioPerine Complex
6 mg
Bioperine Black Pepper extract
0 NP
Ginger extract
0 NP
Adults 18–50 Women
Report overview
Papain · 100 mg OverallScore66
D+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The clearly disclosed 100 mg papain amount reaches the targeted high-dose range. No activity units or Carica papaya source are supplied, so enzyme potency and source purity remain uncertain. Liquid softgel delivery does not establish enteric protection, leaving the high serving cost difficult to justify for papain specifically.

Boswellia · 200 mg OverallScore51
F Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyB- Value

The 200 mg extract is clearly disclosed and paired with BioPerine in a lipid-based softgel, which may support absorption. Boswellic acid is named without a percentage, and AKBA is not identified, leaving active strength uncertain. The dose is slightly below the usual standard-extract range, while the near-median cost provides acceptable but not exceptional value.

Turmeric · 200 mg OverallScore36
C- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyB- Value

The extract lacks a stated curcuminoid percentage, so active potency remains uncertain. A BioPerine-containing complex and liquid softgel base support absorption despite the unclear curcuminoid yield. The serving carries a modest premium that is partly justified by the enhanced delivery system.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of fish oil supplement in maintenance hemodialysis patients: a systematic review and meta-analysis of published randomized controlled trials.
    He L; Li MS; Lin M; Zhao TY; Gao P · European journal of clinical pharmacology · 2016
    Meta-analysis916 participants13 studies pooledAnti-Inflammatory Support forFish Oil
  2. Anti-inflammatory effects of zingiber officinale in type 2 diabetic patients.
    Mahluji S; Ostadrahimi A; Mobasseri M; Ebrahimzade Attari V; Payahoo L · Advanced pharmaceutical bulletin · 2013
    Randomized trial64 participantsAnti-Inflammatory Support forGinger
  3. Effect of ginger on gastric motility and symptoms of functional dyspepsia.
    Hu ML; Rayner CK; Wu KL; Chuah SK; Tai WC; Chou YP; Chiu YC; Chiu KW; Hu TH · World journal of gastroenterology · 2011
    Randomized trial11 participantsDigestive Health forGinger
  4. Randomized, placebo-controlled, double-blind trial of Boswellia serrata in maintaining remission of Crohn's disease: good safety profile but lack of efficacy.
    Holtmeier W; Zeuzem S; Preiss J; Kruis W; Böhm S; Maaser C; Raedler A; Schmidt C; Schnitker J; Schwarz J; Zeitz M; Caspary W · Inflammatory bowel diseases · 2011
    Randomized trial108 participantsAnti-Inflammatory Support forBoswellia
  5. Interventions for treating collagenous colitis.
    Chande N; McDonald JW; Macdonald JK · The Cochrane database of systematic reviews · 2008
    Meta-analysis31 participants1 studies pooledDigestive Health forBoswellia
  6. No effect of fish oil supplementation on serum inflammatory markers and their interrelationships: a randomized controlled trial in healthy, middle-aged individuals.
    Pot GK; Brouwer IA; Enneman A; Rijkers GT; Kampman E; Geelen A · European journal of clinical nutrition · 2010
    Randomized trial77 participantsAnti-Inflammatory Support forFish Oil
  7. Double-blind trial of solid lipid Boswellia serrata particles (SLBSP) vs. standardized Boswellia serrata gum extract (BSE) for osteoarthritis of knee.
    Kulkarni PD; Damle ND; Singh S; Yadav KS; Ghante MR; Bhaskar VH; Hingorani L; Gota VS · Drug metabolism and personalized therapy · 2021
    Randomized trialAnti-Inflammatory Support forBoswellia
  8. The effects of ginger on gallbladder motility in healthy male humans.
    Chuah SK; Wu KL; Tai WC; Changchien CS · Journal of neurogastroenterology and motility · 2012
    Randomized trial19 participantsDigestive Health forGinger
  9. Effects of Cinnamon, Cardamom, Saffron, and Ginger Consumption on Markers of Glycemic Control, Lipid Profile, Oxidative Stress, and Inflammation in Type 2 Diabetes Patients.
    Azimi P; Ghiasvand R; Feizi A; Hariri M; Abbasi B · The review of diabetic studies : RDS · 2016
    Randomized trial204 participantsAnti-Inflammatory Support forGinger
  10. Interventions for treating collagenous colitis.
    Chande N; McDonald JW; MacDonald JK · The Cochrane database of systematic reviews · 2007
    Systematic review31 participants1 studies pooledDigestive Health forBoswellia
  11. A Purported Detoxification Supplement Does Not Improve Body Composition, Waist Circumference, Blood Markers, or Gastrointestinal Symptoms in Healthy Adult Females.
    Tinsley G; Urbina S; Santos E; Villa K; Foster C; Wilborn C; Taylor L · Journal of dietary supplements · 2020
    Randomized trialDigestive Health forGinger
  12. Clinical Benefits of Boswellia Serrata (BOSMAX®) in Early Knee Osteoarthritis: A Randomized, Placebo-Controlled, Double-Blind Study.
    Jayaram M; Kim J; Baek KS; Jung H; Kim J; M K P; T S C; H B S; Ramaiah V; S P · Journal of medicinal food · 2025
    Randomized trial150 participantsAnti-Inflammatory Support forBoswellia
  13. The effect of ginger supplementation on serum C-reactive protein, lipid profile and glycaemia: a systematic review and meta-analysis.
    Mazidi M; Gao HK; Rezaie P; Ferns GA · Food & nutrition research · 2022
    Meta-analysis9 studies pooledAnti-Inflammatory Support forGinger
  14. Effects of fish oil supplementation on biomarkers of vascular endothelial function in middle-aged and older adults: a randomized controlled trial.
    Quan C; Tang W; Qin Y; Nian Z; Li Z; Mao L · Food & function · 2026
    Randomized trial240 participantsAnti-Inflammatory Support forFish Oil
  15. Positive Effects of a Lecithin-Based Delivery Form of Boswellia serrata Extract in Acute Diarrhea of Adult Subjects.
    Giacosa A; Riva A; Petrangolini G; Allegrini P; Fazia T; Bernardinelli L; Peroni G; Rondanelli M · Nutrients · 2022
    Randomized trial49 participantsDigestive Health forBoswellia
  16. A pilot, randomized, double-blind, placebo-controlled trial to assess the safety and efficacy of a novel Boswellia serrata extract in the management of osteoarthritis of the knee.
    Majeed M; Majeed S; Narayanan NK; Nagabhushanam K · Phytotherapy research : PTR · 2019
    Randomized trial48 participantsAnti-Inflammatory Support forBoswellia
  17. Efficacy and safety of steamed ginger extract for gastric health: a randomized, double-blind, placebo-controlled multi-center clinical trial.
    Baek HI; Ha NR; Kim C; Im TJ; Kim YY; Hwang SH; Bae JW · Food & function · 2025
    Randomized trial80 participantsDigestive Health forGinger
  18. Effect of Ginger Supplementation on Proinflammatory Cytokines in Older Patients with Osteoarthritis: Outcomes of a Randomized Controlled Clinical Trial.
    Mozaffari-Khosravi H; Naderi Z; Dehghan A; Nadjarzadeh A; Fallah Huseini H · Journal of nutrition in gerontology and geriatrics · 2017
    Randomized trial120 participantsAnti-Inflammatory Support forGinger
  19. Lowering effects of fish oil supplementation on proinflammatory markers in hypertension: results from a randomized controlled trial.
    Yang B; Ren XL; Li ZH; Shi MQ; Ding F; Su KP; Guo XJ; Li D · Food & function · 2020
    Randomized trial77 participantsAnti-Inflammatory Support forFish Oil
  20. Interventions for treating collagenous colitis.
    Kafil TS; Nguyen TM; Patton PH; MacDonald JK; Chande N; McDonald JW · The Cochrane database of systematic reviews · 2018
    Systematic review31 participants1 studies pooledDigestive Health forBoswellia
  21. Boswellic Acids Improve Clinical Cognitive Scores and Reduce Systemic Inflammation in Patients with Mild to Moderate Alzheimer's Disease.
    Karima S; Aghamollaii V; Mahmoodi Baram S; Balenci L; Lanctôt KL; Kiss A; Tafakhori A; Mahdavi M; Rajaei S; Shateri S; Yarhoseini A; Mokhtari F; Fotouhi A; Riazi A · Journal of Alzheimer's disease : JAD · 2023
    Randomized trial85 participantsAnti-Inflammatory Support forBoswellia
  22. A Randomized, Double-Blind, Placebo Controlled, Parallel-Group, Comparative Clinical Study to Evaluate the Efficacy and Safety of OLNP-06 versus Placebo in Subjects with Functional Dyspepsia.
    Panda MPharm SK; Nirvanashetty PhD S; Parachur BTech VA; Krishnamoorthy MPharm C; Dey MSc S · Journal of dietary supplements · 2022
    Randomized trial50 participantsDigestive Health forGinger
  23. Effects of Ginger Supplementation on Markers of Inflammation and Functional Capacity in Individuals with Mild to Moderate Joint Pain.
    Broeckel J; Estes L; Leonard M; Dickerson BL; Gonzalez DE; Purpura M; Jäger R; Sowinski RJ; Rasmussen CJ; Kreider RB · Nutrients · 2025
    Randomized trial30 participantsAnti-Inflammatory Support forGinger
  24. Eicosapentaenoic acid supplementation alleviates pruritus, enhances skin moisture, and mitigates depression in maintenance hemodialysis patients.
    Lin YL; Wang CL; Chiang TI · Frontiers in nephrology · 2024
    Randomized trial60 participantsAnti-Inflammatory Support forFish Oil
  25. Supplementation with a lecithin-based delivery form of Boswellia serrata extract (Casperome®) controls symptoms of mild irritable bowel syndrome.
    Belcaro G; Gizzi G; Pellegrini L; Corsi M; Dugall M; Cacchio M; Feragalli B; Togni S; Riva A; Eggenhoffner R; Giacomelli L · European review for medical and pharmacological sciences · 2018
    Non-randomized trial71 participantsDigestive Health forBoswellia
  26. A Standardized Boswellia serrata Extract Improves Knee Joint Function and Cartilage Morphology in Human Volunteers with Mild to Moderate Osteoarthritis in a Randomized Placebo-Controlled Study.
    Kumar B; Ghaytidak AB; Pandey AK; Somepalli RR; Sarda P; Raychaudhuri SP; Rokkam MP · Journal of the American Nutrition Association · 2025
    Randomized trial80 participantsAnti-Inflammatory Support forBoswellia
  27. The effects of ginger supplementation on common gastrointestinal symptoms in patients with relapsing-remitting multiple sclerosis: a double-blind randomized placebo-controlled trial.
    Foshati S; Poursadeghfard M; Heidari Z; Amani R · BMC complementary medicine and therapies · 2023
    Randomized trial52 participantsDigestive Health forGinger
  28. The effect of ginger supplementation on some immunity and inflammation intermediate genes expression in patients with active Rheumatoid Arthritis.
    Aryaeian N; Shahram F; Mahmoudi M; Tavakoli H; Yousefi B; Arablou T; Jafari Karegar S · Gene · 2019
    Randomized trial70 participantsAnti-Inflammatory Support forGinger
  29. Efficacy of fish oil and its components in the management of psoriasis: a systematic review of 18 randomized controlled trials.
    Chen X; Hong S; Sun X; Xu W; Li H; Ma T; Zheng Q; Zhao H; Zhou Y; Qiang Y; Li B; Li X · Nutrition reviews · 2021
    Meta-analysis927 participants18 studies pooledAnti-Inflammatory Support forFish Oil
  30. A Meta-Analysis of the Impact of Nutritional Supplementation on Osteoarthritis Symptoms.
    Mathieu S; Soubrier M; Peirs C; Monfoulet LE; Boirie Y; Tournadre A · Nutrients · 2022
    Meta-analysis1,438 participants12 studies pooledAnti-Inflammatory Support forGinger
  31. A standardized Boswellia serrata extract shows improvements in knee osteoarthritis within five days-a double-blind, randomized, three-arm, parallel-group, multi-center, placebo-controlled trial.
    Majeed A; Majeed S; Satish G; Manjunatha R; Rabbani SN; Patil NVP; Mundkur L · Frontiers in pharmacology · 2024
    Randomized trial105 participantsAnti-Inflammatory Support forBoswellia
  32. The effects of fish oil supplementation on markers of inflammation in chronic kidney disease patients.
    Deike E; Bowden RG; Moreillon JJ; Griggs JO; Wilson RL; Cooke M; Shelmadine BD; Beaujean AA · Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2013
    Randomized trial31 participantsAnti-Inflammatory Support forFish Oil
  33. Ginger on Human Health: A Comprehensive Systematic Review of 109 Randomized Controlled Trials.
    Anh NH; Kim SJ; Long NP; Min JE; Yoon YC; Lee EG; Kim M; Kim TJ; Yang YY; Son EY; Yoon SJ; Diem NC; Kim HM; Kwon SW · Nutrients · 2020
    Systematic review109 studies pooledDigestive Health forGinger
  34. Ginger supplementation and metabolic health: an umbrella review of meta-analyses of randomized trials.
    Musazadeh V; Morvaridi M; Hosseini-Roknabadi SM; Mahmoudinezhad M; Jafari A; Shidfar F · Diabetology & metabolic syndrome · 2026
    Meta-analysis43,570 participants36 studies pooledAnti-Inflammatory Support forGinger
  35. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee.
    Sengupta K; Alluri KV; Satish AR; Mishra S; Golakoti T; Sarma KV; Dey D; Raychaudhuri SP · Arthritis research & therapy · 2009
    Randomized trial75 participantsAnti-Inflammatory Support forBoswellia
  36. The effects of ω-3 fish oil emulsion-based parenteral nutrition plus combination treatment for acute paraquat poisoning.
    Meng Z; Dong Y; Gao H; Yao D; Gong Y; Meng Q; Zheng T; Cui X; Su X; Tian Y · The Journal of international medical research · 2019
    Randomized trial174 participantsAnti-Inflammatory Support forFish Oil
  37. [Is ginger a relevant antiemetic for postoperative nausea and vomiting?].
    Morin AM; Betz O; Kranke P; Geldner G; Wulf H; Eberhart LH · Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS · 2004
    Meta-analysis538 participantsDigestive Health forGinger
  38. Effect of ginger powder supplementation on nitric oxide and C-reactive protein in elderly knee osteoarthritis patients: A 12-week double-blind randomized placebo-controlled clinical trial.
    Naderi Z; Mozaffari-Khosravi H; Dehghan A; Nadjarzadeh A; Huseini HF · Journal of traditional and complementary medicine · 2016
    Randomized trial120 participantsAnti-Inflammatory Support forGinger
  39. A full-spectrum Boswellia serrata extract with enhanced bioavailability, and its co-delivered system with curcumin alleviate pain and stiffness associated with moderate spondylitis: a randomized double-blind, placebo-controlled, 3-arm study.
    Mamatha K; Prabhakaran P; Syam Das S; Kanjoormana Aryan M; Thomas J · Frontiers in pharmacology · 2025
    Randomized trial105 participantsAnti-Inflammatory Support forBoswellia
  40. A systematic review and meta-analysis of the n-3 polyunsaturated fatty acids effects on inflammatory markers in colorectal cancer.
    Mocellin MC; Camargo CQ; Nunes EA; Fiates GMR; Trindade EBSM · Clinical nutrition (Edinburgh, Scotland) · 2017
    Meta-analysis475 participants9 studies pooledAnti-Inflammatory Support forFish Oil
  41. Clinical Evaluation of the Use of Ginger Extract in the Preventive Management of Motion Sickness.
    Nunes CP; Rodrigues CC; Cardoso CAF; Cytrynbaum N; Kaufman R; Rzetelna H; Goldwasser G; Santos A; Oliveira L; Geller M · Current therapeutic research, clinical and experimental · 2022
    Randomized trial31 participantsDigestive Health forGinger
  42. Comparative Clinical Evaluation of Chamomile, Sage, and Ginger Mouthwashes in Reducing Plaque and Gingival Inflammation.
    Lile IE; Samoilă AOJ; Cojocariu C; Tapalagă G; Oláh NK; Stana OL; Berari A; Marian D · Antibiotics (Basel, Switzerland) · 2026
    Randomized trial175 participantsAnti-Inflammatory Support forGinger
  43. Effects of Omega-3 Fatty Acid Intake in Patients Undergoing Dialysis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Liu R; Jiang J; Fu Z; Liu C; Yao L; Quan H · Journal of the American Nutrition Association · 2022
    Meta-analysis49 studies pooledAnti-Inflammatory Support forFish Oil
  44. Anti-inflammatory and anti-cancer activities of frankincense: Targets, treatments and toxicities.
    Efferth T; Oesch F · Seminars in cancer biology · 2022
    Systematic reviewAnti-Inflammatory Support forBoswellia
  45. The Effect of Ginger (Zingiber officinalis) and Artichoke (Cynara cardunculus) Extract Supplementation on Functional Dyspepsia: A Randomised, Double-Blind, and Placebo-Controlled Clinical Trial.
    Giacosa A; Guido D; Grassi M; Riva A; Morazzoni P; Bombardelli E; Perna S; Faliva MA; Rondanelli M · Evidence-based complementary and alternative medicine : eCAM · 2015
    Randomized trialDigestive Health forGinger
  46. Dose-dependent effects of fish oil on cardio-metabolic biomarkers in healthy middle-aged and elderly Chinese people: a double-blind randomized controlled trial.
    Song J; Hu M; Li C; Yang B; Ding Q; Wang C; Mao L · Food & function · 2018
    Randomized trial201 participantsAnti-Inflammatory Support forFish Oil
  47. Role of resveratrol supplementation in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2: A randomized, placebo-controlled trial.
    Mahjabeen W; Khan DA; Mirza SA · Complementary therapies in medicine · 2022
    Randomized trial110 participantsAnti-Inflammatory Support forResveratrol
  48. Resveratrol decreases local inflammatory markers and systemic endotoxin in patients with aggressive periodontitis.
    Zhang Q; Xu S; Xu W; Zhou Y; Luan H; Wang D · Medicine · 2022
    Randomized trial160 participantsAnti-Inflammatory Support forResveratrol
  49. Effects of resveratrol supplementation on inflammatory markers, fatigue scale, fasting blood sugar and lipid profile in relapsing-remitting multiple sclerosis patients: a double-blind, randomized placebo-controlled trial.
    Keramatzadeh S; Hosseini SA; Majdinasab N; Cheraghian B; Zilaee M · Nutritional neuroscience · 2025
    Randomized trial55 participantsAnti-Inflammatory Support forResveratrol
  50. One-year consumption of a grape nutraceutical containing resveratrol improves the inflammatory and fibrinolytic status of patients in primary prevention of cardiovascular disease.
    Tomé-Carneiro J; Gonzálvez M; Larrosa M; Yáñez-Gascón MJ; García-Almagro FJ; Ruiz-Ros JA; García-Conesa MT; Tomás-Barberán FA; Espín JC · The American journal of cardiology · 2012
    Randomized trial75 participantsAnti-Inflammatory Support forResveratrol
  51. Effects of resveratrol supplementation on risk factors of non-communicable diseases: A meta-analysis of randomized controlled trials.
    Guo XF; Li JM; Tang J; Li D · Critical reviews in food science and nutrition · 2019
    Meta-analysis1,069 participants29 studies pooledAnti-Inflammatory Support forResveratrol
  52. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  53. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  54. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  55. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  56. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  57. Antioxidant Supplements and Gastrointestinal Diseases: A Critical Appraisal.
    Khan I; Samson SE; Grover AK · Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2018
    Narrative reviewDigestive Health forBoswellia
  58. The role of enzyme supplementation in digestive disorders.
    Roxas M · Alternative medicine review : a journal of clinical therapeutic · 2009
    Narrative reviewDigestive Health forBromelain
  59. Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study.
    Delgarm P; Mokhtare M; Ebrahimi Daryani N; Abolghasemi J; Rahideh ST · Scientific reports · 2025
    Randomized trial70 participantsDigestive Health forBromelain
  60. The incidence and clinical implications of hypersensitivity to papain in an allergic population, confirmed by blinded oral challenge.
    Mansfield LE; Ting S; Haverly RW; Yoo TJ · Annals of allergy · 1985
    Clinical trial500 participantsDigestive Health forPapain
  61. Papaya preparation (Caricol®) in digestive disorders
    Muss C, Mosgoeller W, Endler T · Neuro Endocrinology Letters · 2013
    Randomized trial76 participantsDigestive Health forPapain