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Glutathione 200 mg

Vital Nutrients
4.9
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(18 ratings)
Glutathione 400 mg
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Score75
400 mg of reduced glutathione anchors a limited multi-ingredient option with limited value. Its main trade-off is the high dose within a broader formula, which may be either convenient or restrictive depending on the intended routine.
How scoring works
Quantity:100 Capsule(s) • (50 servings)
Goals:
Anti-Inflammatory Support

Score 75

400 mg of reduced glutathione anchors a limited multi-ingredient option with limited value. Its main trade-off is the high dose within a broader formula, which may be either convenient or restrictive depending on the intended routine.
How scoring works
$82.99($1.65 per serving)
iHerb
$ 82.99
Pure Formulas
$ 82.99
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Analysis

The 400 mg serving provides reduced glutathione alongside Vitamin C in capsule(s). The high-dose amount sits within a broader formula, so each included ingredient should fit the intended use.

The amount is stated, but the supplied information leaves some formulation detail unspecified. Value is a notable trade-off compared with more economical options, and the broader ingredient list needs more careful comparison with simpler alternatives.

The strongest practical fit is anti-inflammatory support, with related assessments also supporting glutathione-focused use. The main decision is whether 400 mg and the capsule(s) format match the user's preferred routine and budget.

Who is it for
  • Adults seeking a high-dose Glutathione supplement
  • People who prefer capsule(s) for reduced glutathione
  • Users focused on anti-inflammatory support
Best for
  • Anti-Inflammatory Support support

Pros

  • Clearly stated 400 mg amount
  • Includes reduced glutathione with additional active ingredients
  • Serving amount is easy to identify
  • Simple format makes alternatives easy to compare

Cons

  • 400 mg offers little flexibility for lower-dose use
  • Capsule(s) may not suit every user's format preference
  • Value is less competitive than stronger alternatives

Nutrient quality

90 Highest impact

Substantial reduced glutathione and vitamin C create a coherent antioxidant combination. Plain capsule delivery remains less optimized than liposomal or acetylated forms.

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Ingredient transparency

82 Highest impact

Active amounts are clearly disclosed without a hidden blend. Complete directions and inactive ingredients remain absent.

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Customer satisfaction

63 Moderate impact

Customer sentiment is very strong. The very small rating base provides weak confidence in the average, while no narrative feedback was supplied.

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Value for money

56 Moderate impact

Serving economics are weak. Quality limitations keep practical value low.

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Goals

Impact
Highest effect
B+ Goal FitA- Strength of SupportB CoverageA+ Formula Quality
Vitamin C · 650 mgGlutathione · 400 mg

Reduced Setria glutathione and vitamin C form a strong antioxidant combination with clear relevance to inflammatory balance. Both are supplied at meaningful disclosed amounts.

Vitamin C may help regenerate antioxidant capacity, giving the pairing useful synergy. The standard capsule is less optimized than liposomal delivery, but the formula remains focused and potent.

Study evidence
Glutathione Disputed 2 studies
Vitamin C Supportive 50 studies

Ingredients

IngredientAmount per serving
Vitamin C (Ascorbic Acid)
650 mg
reduced Glutathione (Setria Glutathione)
400 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
C- Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyF Value

Setria provides a recognized high-purity source, and the 400 mg reduced glutathione dose is substantial. A standard capsule does not offer the absorption advantages of liposomal or S-acetyl delivery. The one-capsule serving is convenient, but its serving cost is high for a non-liposomal form.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Serum type III procollagen, procollagen V, tumour necrosis factor-a, interleukin-6 in liver cirrhosis after antiviral treatment.
    Li W; Liu X; Bi F · Journal of medical biochemistry · 2025
    Randomized trial92 participantsAnti-Inflammatory Support forGlutathione
  2. Evaluation of the antioxidant and anti-inflammatory effect of sublingual glutathione on COPD patients.
    Farag A; Abass W; Qassem H · Journal of medicine and life · 2024
    Cohort study50 participantsAnti-Inflammatory Support forGlutathione
  3. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  4. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  5. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  6. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  7. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C