Reduced L-Glutathione 250 mg
Solgar
Reduced L-Glutathione 250 mg
4.7
★ ★ ★ ★ ★
(1020 ratings)
Glutathione 250 mg
Score 62.0
A larger quantity of Solgar's 250mg reduced L-Glutathione, offering a slight price improvement but remaining costly relative to market alternatives.
Quantity: 60 Capsule(s)Servings size: 1 Vegetable Capsule(s) (60 servings)
Selected goals:
Other goals:
Anti-Aging
Detoxification
Skin Health
Anti-Inflammatory Support
leaderboard Score 62.0
A larger quantity of Solgar's 250mg reduced L-Glutathione, offering a slight price improvement but remaining costly relative to market alternatives.
insights Analysis
This is essentially the same Solgar product as ID 130984, offering 250 mg of Reduced L-Glutathione in capsule form, but in a larger 60-count quantity. While the larger bottle slightly improves the price per serving compared to the 30-count bottle, it remains one of the more expensive options for this dosage and form. It still lacks the explicit mention of a patented, highly absorbed form like Setria, which many competitors offer at better price points.
- Provides a common and generally effective 250mg dose of reduced glutathione.
- Larger bottle offers a slightly better price point than the smaller one.
- Still notably expensive per serving compared to many alternatives.
- Lacks specification of a premium, clinically studied form (e.g., Setria).
$30.74($0.51 per serving)
 iHerb | $ 30.74 | |
 Amazon | $ 30.74 | |
 Vitacost | $ 32.49 | |
 Daily Vita | $ 35.80 |
bolt Effectiveness for goals
The effectiveness of oral glutathione supplementation for directly increasing intracellular glutathione levels is a subject of ongoing research. While some studies suggest that specific forms, like liposomal or S-acetyl-glutathione, may help raise plasma glutathione, traditional forms face challenges with absorption. The body's natural synthesis of glutathione is a primary regulator of its levels.
The effectiveness of oral glutathione can vary due to challenges with absorption and degradation in the digestive system. Some forms, like liposomal or S-acetyl glutathione, are designed to improve bioavailability. Research on the systemic impact of various oral forms is ongoing.
Traditional reduced glutathione supplements have historically faced challenges with absorption due to degradation in the digestive tract. Newer forms, such as liposomal or S-acetyl-glutathione, are specifically designed to improve bioavailability and are generally considered more effectively absorbed. Research continues to evaluate the optimal delivery methods for glutathione.
Glutathione is a primary antioxidant in the body, crucial for neutralizing free radicals and combating oxidative stress. Supplementation is hypothesized to support the body's natural antioxidant defenses. The extent of this effect can depend on the supplement form and individual physiological factors.
Some research suggests that high doses of oral glutathione might have skin-lightening effects by inhibiting melanin production, but the evidence is not conclusive and often involves specific populations. These studies often require high dosages and more robust, larger-scale research is needed to confirm efficacy for this purpose. It is not approved for this use by major health authorities.
schedule Dosage, timing & forms
Liposomal glutathione encapsulates glutathione in tiny lipid bubbles (liposomes), which are designed to protect it from degradation in the digestive tract. This delivery method aims to enhance its absorption and bioavailability compared to standard oral reduced glutathione. The liposomal structure helps transport the glutathione more efficiently into the bloodstream.
N-acetylcysteine (NAC) is a precursor that the body uses to synthesize its own glutathione. While not glutathione itself, supplementing with NAC is a common strategy to support the body's endogenous glutathione production. It provides cysteine, a crucial amino acid needed for glutathione synthesis.
Oral glutathione dosages can vary widely depending on the specific form and individual needs, often ranging from 250 mg to 1000 mg per day. It's best to follow the manufacturer's recommendations on the product label. Consulting with a healthcare professional can provide personalized guidance.
Typical oral glutathione dosages can range from 250 mg to 1000 mg per day. The specific amount may vary depending on the product formulation and individual needs. It is advisable to follow the manufacturer's recommendations.
Reduced glutathione (GSH) is the active form naturally found in the body, but it can be prone to degradation during digestion when taken orally. S-acetyl glutathione is a modified form designed for improved stability and bioavailability. The acetyl group is intended to protect it until absorption, allowing it to be cleaved off inside cells to release active glutathione.
health_and_safety Safety & interactions
Oral glutathione is generally considered safe for most adults when taken in appropriate doses. Some individuals have reported mild side effects such as abdominal cramps, bloating, or allergic reactions like rash. Inhaled glutathione might cause asthma exacerbation in sensitive individuals.
Oral glutathione supplements are generally well-tolerated by most individuals. Some people might experience mild gastrointestinal discomfort, such as abdominal cramps or bloating. Rarely, allergic reactions like rash have been reported, and inhaled forms might trigger asthma in susceptible individuals.
There is limited information on significant drug interactions with glutathione supplements. However, it is always advisable to consult a healthcare professional, especially when taking prescription medications. They can assess potential interactions based on your specific health profile.
The maximum safe dosage for glutathione can vary depending on the form, individual health, and specific application. While studies have used oral doses up to 1000 mg/day, it is crucial to follow product label instructions and consult a healthcare provider for personalized guidance. Excessive doses may not provide additional benefits and could lead to unknown effects.
Insufficient research is available regarding the safety of glutathione supplementation during pregnancy and breastfeeding. For this reason, it is generally recommended to avoid use or consult a healthcare provider before considering supplementation. A healthcare professional can weigh the potential benefits against any unknown risks.
Ingredients
| Ingredient | Amount per serving |
|---|---|
L-Glutathione | 250 mg |
Categories
Glutathione 62.0
Within the glutathione supplement category, it delivers the ingredient, but its pricing strategy makes it less attractive compared to numerous competitors offering better value or enhanced forms for the same dosage.
Goals
Anti-Aging 62.0
While 250mg of reduced glutathione can aid in anti-aging by combating oxidative stress, the high cost per dose impacts its overall value for sustained use, making other products more appealing for long-term anti-aging strategies.
Detoxification 62.0
This dose supports detoxification pathways, but more cost-effective options are available for those seeking long-term or higher intake for liver support, diminishing its competitive edge.
Skin Health 62.0
Glutathione's role in skin health is present, but the product's high price point makes it a less optimal choice for those seeking consistent supplementation for skin benefits due to budget constraints.
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