Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- An Evaluation of the Effects of Pineapple-Extract and Bromelain-Based Treatment after Mandibular Third Molar Surgery: A Randomized Three-Arm Clinical Study.
Colletti A; Procchio C; Pisano M; Martelli A; Pellizzato M; Cravotto G · Nutrients · 2024
Randomized trial42 participantsflagAnti-Inflammatory Support forscienceBromelain
- A pilot, randomized, double-blind, placebo-controlled trial to assess the safety and efficacy of a novel Boswellia serrata extract in the management of osteoarthritis of the knee.
Majeed M; Majeed S; Narayanan NK; Nagabhushanam K · Phytotherapy research : PTR · 2019
Randomized trial48 participantsflagAnti-Inflammatory Support forscienceBoswellia
- The role of enzyme supplementation in digestive disorders.
Roxas M · Alternative medicine review : a journal of clinical therapeutic · 2009
Narrative reviewflagDigestive Health forscienceBromelain
- Effect of Oral Administration of Bromelain on Postoperative Discomfort After Third Molar Surgery.
Ghensi P; Cucchi A; Creminelli L; Tomasi C; Zavan B; Maiorana C · The Journal of craniofacial surgery · 2018
Randomized trial84 participantsflagAnti-Inflammatory Support forscienceBromelain
- Double-blind trial of solid lipid Boswellia serrata particles (SLBSP) vs. standardized Boswellia serrata gum extract (BSE) for osteoarthritis of knee.
Kulkarni PD; Damle ND; Singh S; Yadav KS; Ghante MR; Bhaskar VH; Hingorani L; Gota VS · Drug metabolism and personalized therapy · 2021
Randomized trialflagAnti-Inflammatory Support forscienceBoswellia
- Is bromelain an effective drug for the control of pain and inflammation associated with impacted third molar surgery? Systematic review and meta-analysis.
de A C Almeida R; de Sousa Lima FCM; do E Vasconcelos BC · International journal of oral and maxillofacial surgery · 2019
Meta-analysis252 participants5 studies pooledflagAnti-Inflammatory Support forscienceBromelain
- Randomized, placebo-controlled, double-blind trial of Boswellia serrata in maintaining remission of Crohn's disease: good safety profile but lack of efficacy.
Holtmeier W; Zeuzem S; Preiss J; Kruis W; Böhm S; Maaser C; Raedler A; Schmidt C; Schnitker J; Schwarz J; Zeitz M; Caspary W · Inflammatory bowel diseases · 2011
Randomized trial108 participantsflagAnti-Inflammatory Support forscienceBoswellia
- Clinical Benefits of Boswellia Serrata (BOSMAX®) in Early Knee Osteoarthritis: A Randomized, Placebo-Controlled, Double-Blind Study.
Jayaram M; Kim J; Baek KS; Jung H; Kim J; M K P; T S C; H B S; Ramaiah V; S P · Journal of medicinal food · 2025
Randomized trial150 participantsflagAnti-Inflammatory Support forscienceBoswellia
- Boswellic Acids Improve Clinical Cognitive Scores and Reduce Systemic Inflammation in Patients with Mild to Moderate Alzheimer's Disease.
Karima S; Aghamollaii V; Mahmoodi Baram S; Balenci L; Lanctôt KL; Kiss A; Tafakhori A; Mahdavi M; Rajaei S; Shateri S; Yarhoseini A; Mokhtari F; Fotouhi A; Riazi A · Journal of Alzheimer's disease : JAD · 2023
Randomized trial85 participantsflagAnti-Inflammatory Support forscienceBoswellia
- A Standardized Boswellia serrata Extract Improves Knee Joint Function and Cartilage Morphology in Human Volunteers with Mild to Moderate Osteoarthritis in a Randomized Placebo-Controlled Study.
Kumar B; Ghaytidak AB; Pandey AK; Somepalli RR; Sarda P; Raychaudhuri SP; Rokkam MP · Journal of the American Nutrition Association · 2025
Randomized trial80 participantsflagAnti-Inflammatory Support flagJoint Health forscienceBoswellia
- A standardized Boswellia serrata extract shows improvements in knee osteoarthritis within five days-a double-blind, randomized, three-arm, parallel-group, multi-center, placebo-controlled trial.
Majeed A; Majeed S; Satish G; Manjunatha R; Rabbani SN; Patil NVP; Mundkur L · Frontiers in pharmacology · 2024
Randomized trial105 participantsflagAnti-Inflammatory Support flagJoint Health forscienceBoswellia
- Therapeutic efficacy of bromelain in impacted third molar surgery: a randomized controlled clinical study.
Ordesi P; Pisoni L; Nannei P; Macchi M; Borloni R; Siervo S · Quintessence international (Berlin, Germany : 1985) · 2016
Randomized trial80 participantsflagAnti-Inflammatory Support forscienceBromelain
- Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical trials.
Mendes ML; do Nascimento-Júnior EM; Reinheimer DM; Martins-Filho PR · Medicina oral, patologia oral y cirugia bucal · 2019
Meta-analysis6 studies pooledflagAnti-Inflammatory Support forscienceBromelain
- Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain.
Müller S; März R; Schmolz M; Drewelow B; Eschmann K; Meiser P · Phytotherapy research : PTR · 2013
Randomized trial12 participantsflagAnti-Inflammatory Support forscienceBromelain
- Therapeutic uses of pineapple-extracted bromelain in surgical care - A review.
Muhammad ZA; Ahmad T · JPMA. The Journal of the Pakistan Medical Association · 2019
Narrative reviewflagAnti-Inflammatory Support forscienceBromelain
- Positive Effects of a Lecithin-Based Delivery Form of Boswellia serrata Extract in Acute Diarrhea of Adult Subjects.
Giacosa A; Riva A; Petrangolini G; Allegrini P; Fazia T; Bernardinelli L; Peroni G; Rondanelli M · Nutrients · 2022
Randomized trial49 participantsflagDigestive Health forscienceBoswellia
- Antioxidant Supplements and Gastrointestinal Diseases: A Critical Appraisal.
Khan I; Samson SE; Grover AK · Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2018
Narrative reviewflagDigestive Health forscienceBoswellia
- Supplementation with a lecithin-based delivery form of Boswellia serrata extract (Casperome®) controls symptoms of mild irritable bowel syndrome.
Belcaro G; Gizzi G; Pellegrini L; Corsi M; Dugall M; Cacchio M; Feragalli B; Togni S; Riva A; Eggenhoffner R; Giacomelli L · European review for medical and pharmacological sciences · 2018
Non-randomized trial71 participantsflagDigestive Health forscienceBoswellia
- Interventions for treating collagenous colitis.
Kafil TS; Nguyen TM; Patton PH; MacDonald JK; Chande N; McDonald JW · The Cochrane database of systematic reviews · 2018
Systematic review31 participants1 studies pooledflagDigestive Health forscienceBoswellia
- Interventions for treating collagenous colitis.
Chande N; McDonald JW; MacDonald JK · The Cochrane database of systematic reviews · 2007
Systematic review31 participants1 studies pooledflagDigestive Health forscienceBoswellia
- Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study.
Delgarm P; Mokhtare M; Ebrahimi Daryani N; Abolghasemi J; Rahideh ST · Scientific reports · 2025
Randomized trial70 participantsflagDigestive Health forscienceBromelain
- Oral herbal therapies for treating osteoarthritis.
Cameron M; Chrubasik S · The Cochrane database of systematic reviews · 2015
Meta-analysis5,980 participants49 studies pooledflagJoint Health forscienceBoswellia
- Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled study.
Haroyan A; Mukuchyan V; Mkrtchyan N; Minasyan N; Gasparyan S; Sargsyan A; Narimanyan M; Hovhannisyan A · BMC complementary and alternative medicine · 2018
Randomized trial201 participantsflagJoint Health forscienceBoswellia
- A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee.
Sengupta K; Alluri KV; Satish AR; Mishra S; Golakoti T; Sarma KV; Dey D; Raychaudhuri SP · Arthritis research & therapy · 2009
Randomized trial75 participantsflagJoint Health forscienceBoswellia
- Bromelain as a Treatment for Osteoarthritis: a Review of Clinical Studies.
Brien S; Lewith G; Walker A; Hicks SM; Middleton D · Evidence-based complementary and alternative medicine : eCAM · 2024
Narrative reviewflagJoint Health forscienceBromelain
- Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis.
Kasemsuk T; Saengpetch N; Sibmooh N; Unchern S · Clinical rheumatology · 2017
Randomized trial40 participantsflagJoint Health forscienceBromelain
- Oral enzyme combination therapy reduces systemic inflammation, urinary CTXII and pain in knee osteoarthritis: a proof-of-mechanism, randomised, crossover, double-blind, placebo-controlled trial.
Henrotin Y; Pap T; Lieten S; Badot V; Dubuc JE; Urbin-Choffray D; von Eynatten M; Johansen OE; Rau S; Brabants K · RMD open · 2025
Randomized trial45 participantsflagJoint Health forscienceBromelain
- Efficacy, tolerability, and safety of an oral enzyme combination vs diclofenac in osteoarthritis of the knee: results of an individual patient-level pooled reanalysis of data from six randomized controlled trials
Ueberall MA, Mueller-Schwefe GH, Wigand R, Essner U · Journal of Pain Research · 2016
Meta-analysis697 participants6 studies pooledflagJoint Health forscienceBromelain
- The safety and efficacy of an enzyme combination in managing knee osteoarthritis pain in adults: a randomized, double-blind, placebo-controlled trial
Bolten WW, Glade MJ, Raum S, Ritz BW · Arthritis · 2015
Randomized trial150 participantsflagJoint Health forscienceBromelain