Product Image

Igniter Blue Raspberry

ALLMAX SPORT
4.6
★ ★ ★ ★ ★
(355 ratings)
Creatine 3000 mg
Folate 402 mcg
Tyrosine 1500 mg
Niacin 21 mg
Taurine 2100 mg
Caffeine 399 mg
Beta-Alanine 3300 mg
Product Image
Score72
Broad, well-disclosed workout ingredients cover strength, endurance, and focus. Nearly 400 mg caffeine sharply limits timing and suitability.
How scoring works
Quantity:320 Gram(s) • (17 servings)
Goals:
Energy
Weight Gain
Fitness
Muscle Gain
Brain Health
Mental Focus
Productivity Boost
Metabolism Boost

Score 72

Broad, well-disclosed workout ingredients cover strength, endurance, and focus. Nearly 400 mg caffeine sharply limits timing and suitability.
How scoring works

Also available as

7 options
4000mg Beta-Alanine • 90 Capsule(s) servings 4000mg Beta-Alanine • 90 Capsule(s) • 90 servings $19.99 ($0.22 per serving) 450mg Caffeine • 60 Capsule(s) servings 450mg Caffeine • 60 Capsule(s) • 60 servings $17.57 ($0.29 per serving) Green Apple B4 27.5 mg • 60 Capsule(s) • 60 servings $25.32 ($0.42 per serving) Watermelon Fenugreek 100 mg, Magnesium 450 mg +2 more • 80 Capsule(s) • 20 servings $13.49 ($0.67 per serving) 200 servings Potassium 170 mg, Protein 27 Gram(s) • 2 lb(s) • 31 servings $59.99 ($1.93 per serving) 480 servings 31 Gram(s) • 2 Pound(s) • 29 servings $59.99 ($2.06 per serving) Fruit Punch 1 Capsule(s) • 60 Capsule(s) • 20 servings
$23.99($1.41 per serving)
iHerb
$ 24.99
Amazon
$ 23.99
Vitacost
$ 26.49
Report prices

Analysis

Creatine monohydrate, beta-alanine, and taurine are each supplied near practical workout amounts. Tyrosine at 1,500 mg adds meaningful focus support, while 3,000 mg citrulline malate provides a more modest pump contribution.

Active quantities are clearly listed, and methylfolate plus methylcobalamin improve the vitamin forms. The exact caffeine and tyrosine forms are not specified, and arginine AKG is too light to add much.

The formula suits experienced users who want strength, endurance, and strong stimulation in one serving. A nearly 400 mg caffeine load makes it difficult to use frequently or later in the day.

Who is it for
  • Experienced stimulant users
  • Strength and conditioning trainees
  • Adults training early in the day
Best for
  • Strength-oriented pre-workout use
  • Muscular endurance
  • High-energy training sessions

Pros

  • Includes 3,000 mg creatine monohydrate
  • Substantial beta-alanine and taurine
  • Meaningful tyrosine amount
  • Uses methylfolate and methylcobalamin

Cons

  • Caffeine amount is extremely high
  • Citrulline malate is only moderately dosed
  • Arginine AKG amount is small
  • Some active forms are unspecified

Warnings

  • The 399 mg caffeine serving may cause jitters, anxiety, rapid heartbeat, higher blood pressure, or major sleep disruption.
  • Beta-alanine can cause temporary tingling or skin prickling, particularly at the full 3,300 mg amount.
  • The 21 mg niacin amount may cause warmth, flushing, or itching in sensitive users.

Nutrient quality

71 High impact

Strong doses of several core performance ingredients make the blend purposeful. Very high caffeine and modest citrulline malate reduce balance and broad suitability.

Ingredient transparency

80 High impact

Every listed active has a specific amount and no proprietary blend conceals the formula. Directions and inactive ingredients are not supplied.

Customer satisfaction

67 High impact

The favorable rating is supported by a moderate review base. No review details are present to identify recurring tolerance or workout concerns.

Value for money

68 High impact

Meaningful core doses support the formula value, but the short bottle life weakens each serving. High stimulant intensity also limits category appeal.

Report analysis

Goals

Energy
Energy
Impact
Highest effect
A+ Goal FitA Strength of SupportA CoverageA- Formula Quality
Vitamin B12 · 6 mcgCaffeine · 399 mgCreatine · 3000 mg

Caffeine, creatine, beta-alanine, tyrosine, taurine, and citrulline create powerful acute alertness and workout-performance support. The formula addresses both mental drive and muscular fatigue with several evidence-based ingredients.

Caffeine is extremely high in a full serving, while creatine, beta-alanine, and tyrosine are present at functional amounts. A full serving should not be combined with other stimulants, and people sensitive to caffeine should avoid it because of possible anxiety, rapid heartbeat, elevated blood pressure, or severe sleep disruption.

Study evidence
Caffeine Supportive 68 studies
Creatine Supportive 49 studies
Weight Gain
Weight Gain
Impact
Highest effect
A Goal FitA- Strength of SupportA- CoverageA- Formula Quality
Creatine · 3000 mgCaffeine · 399 mgBeta-Alanine · 3300 mg

Creatine monohydrate, beta-alanine, taurine, caffeine, and citrulline support higher training volume, power, buffering, and cellular hydration. Creatine at 3,000 mg provides direct lean-mass relevance when used consistently with resistance training.

The formula supplies almost no calories or protein, so it supports hypertrophy training rather than a calorie surplus. Caffeine at 399 mg may cause jitteriness, a rapid heartbeat, anxiety, or sleep disruption that can undermine recovery.

Study evidence
Caffeine Adverse 11 studies
Creatine Supportive 87 studies
Taurine No effect 7 studies
Fitness
Fitness
Impact
Highest effect
A Goal FitA- Strength of SupportA CoverageB+ Formula Quality
Creatine · 3000 mgBeta-Alanine · 3300 mgCaffeine · 399 mg

Beta-alanine, creatine, taurine, tyrosine, citrulline malate, and caffeine create broad support for power, endurance, focus, and pump. Most central actives are clearly disclosed at meaningful sports-nutrition doses.

The caffeine amount approaches the usual healthy-adult daily limit in one serving and may cause jitters, rapid heartbeat, or sleep disruption. Citrulline malate is less substantial than the stronger beta-alanine, creatine, taurine, and tyrosine components.

Study evidence
Caffeine Supportive 255 studies
Creatine Supportive 143 studies
Taurine Supportive 21 studies
Muscle Gain
Muscle Gain
Impact
Highest effect
A- Goal FitB+ Strength of SupportA- CoverageB Formula Quality
Creatine · 3000 mgCaffeine · 399 mgBeta-Alanine · 3300 mg

Creatine monohydrate, beta-alanine, citrulline malate, taurine, and tyrosine provide broad support for strength and training volume. Transparent amounts and recognized forms give the formula good practical depth.

Citrulline is less substantial than the leading actives, and the serving contains nearly four hundred milligrams of caffeine. That stimulant load may cause jitteriness, a rapid heartbeat, or sleep disruption that can impair recovery.

Study evidence
Caffeine Supportive 31 studies
Creatine Supportive 136 studies
Taurine Not classified

No linked studies yet.

Brain Health
Brain Health
Impact
Highest effect
B+ Goal FitA- Strength of SupportB+ CoverageB Formula Quality
Folate · 402 mcgVitamin B12 · 6 mcgVitamin B6 · 3 mgCreatine · 3000 mg

Creatine monohydrate and tyrosine reach meaningful amounts for brain energy and performance under acute stress. Active folate, methylcobalamin, and taurine add complementary metabolic support.

The formula is well dosed for short-term demanding situations but remains a stimulant-heavy pre-workout rather than a daily brain-health product. The 399 mg caffeine content may cause jitteriness, rapid heartbeat, or sleep disruption, especially in caffeine-sensitive users.

Study evidence
Creatine Supportive 35 studies
Folate Supportive 90 studies
Tyrosine Supportive 7 studies
Mental Focus
Mental Focus
Impact
Highest effect
A- Goal FitA Strength of SupportB CoverageC Formula Quality
Folate · 402 mcgVitamin B6 · 3 mgVitamin B12 · 6 mcgCreatine · 3000 mgCaffeine · 399 mg

The pre-workout combines a near-daily-limit caffeine amount with substantial tyrosine for strong alertness and catecholamine support. Active vitamin B6 and methylfolate add useful neurotransmitter cofactors.

The stimulant load is likely to be too intense for many users and lacks theanine or an adaptogen to smooth the effect. It may cause jitters, sleep disruption, anxiety, or a rapid heartbeat in sensitive users.

Study evidence
Caffeine Supportive 128 studies
Folate Mixed 12 studies
Vitamin B6 Disputed 6 studies

Ingredients

IngredientAmount per serving
Calories
15 Calorie(s)
Vitamin B3 (Niacin)
 21 mg
Vitamin B6 (Pyridoxal 5-Phosphate, Pyridoxine Hydrochloride)
 3 mg
Vitamin B9 BioB9 (5-Methyltetrahydrofolate)
 402 mcg
Vitamin B12 (Methylcobalamin)
 6 mcg
Beta-Alanine
3300 mg
Citrulline Malate
3000 mg
Creatine Monohydrate
3000 mg
Taurine
2100 mg
Tyrosine
1500 mg
Arginine AKG
501 mg
Caffeine
399 mg
Adults 18–50 Women
Report overview
Creatine · 3000 mg OverallScore70
B Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyF Value
+5

The 3,000 mg creatine monohydrate serving falls within an effective daily range, but the label does not identify micronization, branded sourcing, or independent purity testing. The added 3,300 mg beta-alanine improves the broader pre-workout formula, yet the cost is high when judged by the amount needed to reach a full creatine dose. The 399 mg caffeine level is a meaningful concern for caffeine-sensitive users and may cause sleep disruption, jitteriness, or a rapid heartbeat.

View ingredientView products
Folate (5-Methyltetrahydrofolate) · 402 mcg OverallScore62
B Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyF Value

Five-methyltetrahydrofolate offers a body-ready form at an appropriate amount, though the active isomer is not explicitly identified. Vitamin B12 falls below the preferred co-supplementation level, and the formula also contains a very high caffeine amount that may be unsuitable for stimulant-sensitive users. High serving cost weakens its value as a folate source.

View ingredientView products
Tyrosine · 1500 mg OverallScore62
D Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The 1,500 mg tyrosine dose is clearly listed and reaches the upper end of the target range, but the label does not confirm the L-form. No branded source, purity grade, or independent testing is shown, and the cost per gram is high. The 399 mg caffeine dose may cause jitteriness, rapid heartbeat, or sleep disruption, especially in caffeine-sensitive users.

View ingredientView products
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<p>Branded Alpha-GPC, phosphatidylserine, acetyl-L-carnitine, tyrosine, and stimulants create deep cognitive support. Compared with the original, its supplied ingredient and goal alignment is a stronger fit for caffeine, tyrosine.</p>
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<p>Citrulline, betaine, glycerol, taurine, glycine, tyrosine, and caffeine provide broad pre-workout support. Compared with the original, its supplied ingredient and goal alignment is a stronger fit for caffeine, creatine, tyrosine.</p>
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C4 Original Pink Lemonade

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<p>The pre-workout may support acute alertness and exercise performance, but disclosed beta-alanine, creatine nitrate, and AAKG amounts are below common full-use levels. A lower serving cost makes it a more economical choice while retaining relevance to niacin, folate.</p>
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Kre-Alkalyn Hardcore

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Green Tea Triple Fat Burner

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<p>Tea extracts and caffeine provide a clear stimulant-based approach to energy and weight-management support. A lower serving cost makes it a more economical choice while retaining relevance to niacin, folate, caffeine.</p>
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Animal Fury Green Apple Flavor

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<p>Citrulline, branched-chain amino acids, beta-alanine, tyrosine, and caffeine form a focused pre-workout. Its combination of ingredient alignment and serving value compares favorably with the original for caffeine, tyrosine.</p>
72 Value

Training Ground PRE Orange Mango

EFX Sports
<p>Citrulline, betaine, glycerol, taurine, glycine, tyrosine, and caffeine provide broad pre-workout support. Its combination of ingredient alignment and serving value compares favorably with the original for caffeine, creatine, tyrosine.</p>
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C4 Original Strawberry Margarita

Cellucor
<p>The pre-workout may support acute alertness and exercise performance, but disclosed beta-alanine, creatine nitrate, and AAKG amounts are below common full-use levels. Its combination of ingredient alignment and serving value compares favorably with the original for niacin, folate.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of caffeine ingestion on cycling performance: a systematic review and meta-analysis.
    Wu J; Xu K; Yin M; Ding X; Wang T; Zhang Q; Wu X; Xiao N · Frontiers in nutrition · 2026
    Meta-analysis226 participants20 studies pooledFitness forCaffeine
  2. Acute Effects of Caffeine Supplementation on Movement Velocity in Resistance Exercise: A Systematic Review and Meta-analysis.
    Raya-González J; Rendo-Urteaga T; Domínguez R; Castillo D; Rodríguez-Fernández A; Grgic J · Sports medicine (Auckland, N.Z.) · 2021
    Meta-analysis12 studies pooledFitness forCaffeine
  3. Can I Have My Coffee and Drink It? A Systematic Review and Meta-analysis to Determine Whether Habitual Caffeine Consumption Affects the Ergogenic Effect of Caffeine.
    Carvalho A; Marticorena FM; Grecco BH; Barreto G; Saunders B · Sports medicine (Auckland, N.Z.) · 2022
    Meta-analysis60 studies pooledFitness forCaffeine
  4. No effects of caffeine on cycling to exhaustion and perceptual responses in non-caffeine-restricted subjects.
    Weippert M; Behrens M; Schlegel M; Schröder T; Tillmann M; Rühe N; Römer R; Mau-Möller A; Bruhn S · Journal of the International Society of Sports Nutrition · 2025
    Randomized trial56 participantsFitness forCaffeine
  5. The Effects of Creatine Supplementation on Upper- and Lower-Body Strength and Power: A Systematic Review and Meta-Analysis.
    Kazeminasab F; Kerchi AB; Sharafifard F; Zarreh M; Forbes SC; Camera DM; Lanhers C; Wong A; Nordvall M; Bagheri R; Dutheil F · Nutrients · 2025
    Meta-analysis1,937 participants69 studies pooledFitness forCreatine
  6. Long-term creatine intake is beneficial to muscle performance during resistance training.
    Vandenberghe K; Goris M; Van Hecke P; Van Leemputte M; Vangerven L; Hespel P · Journal of applied physiology (Bethesda, Md. : 1985) · 1998
    Randomized trial19 participantsFitness forCreatine
  7. Creatine in combination with resistance training and improvement in muscle strength: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusFitness forCreatine
  8. Creatine supplementation and VO2max: a systematic review and meta-analysis.
    Gras D; Lanhers C; Bagheri R; Ugbolue UC; Coudeyre E; Pereira B; Zak M; Bouillon-Minois JB; Dutheil F · Critical reviews in food science and nutrition · 2023
    Meta-analysis424 participants19 studies pooledFitness forCreatine
  9. Creatine Monohydrate Supplementation Does Not Augment Fitness, Performance, or Body Composition Adaptations in Response to Four Weeks of High-Intensity Interval Training in Young Females.
    Forbes SC; Sletten N; Durrer C; Myette-Côté É; Candow D; Little JP · International journal of sport nutrition and exercise metabolism · 2017
    Randomized trial17 participantsFitness forCreatine
  10. Oral taurine improves critical power and severe-intensity exercise tolerance.
    Waldron M; Patterson SD; Jeffries O · Amino acids · 2020
    Randomized trial12 participantsFitness forTaurine
  11. Effects of different doses of taurine supplementation on repeated-sprint performance after exhaustive exercise in a high temperature and humidity environment.
    Cheng X; Lin Y; Li Z · Frontiers in nutrition · 2026
    Randomized trial16 participantsFitness forTaurine
  12. Acute taurine supplementation enhances thermoregulation and endurance cycling performance in the heat.
    Page LK; Jeffries O; Waldron M · European journal of sport science · 2019
    Randomized trial11 participantsFitness forTaurine
  13. Acute Effects of Taurine Supplementation on Maximal Fat Oxidation and FATmax in Recreational Endurance Runners: A Randomized, Placebo-Controlled, Crossover, and Triple-Blinded Study.
    Ghazzagh A; Naderi A; Agha-Alinejad H; Livani A; Sarlak M; Aghamohammadi S; Saunders B · International journal of sport nutrition and exercise metabolism · 2024
    Randomized trial11 participantsFitness forTaurine
  14. Creatine supplementation during resistance training in older adults-a meta-analysis.
    Devries MC; Phillips SM · Medicine and science in sports and exercise · 2014
    Meta-analysis357 participantsAnti-Aging Muscle Gain Weight Gain forCreatine
  15. Strategic creatine supplementation and resistance training in healthy older adults.
    Candow DG; Vogt E; Johannsmeyer S; Forbes SC; Farthing JP · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2016
    Randomized trial39 participantsAnti-Aging Weight Gain forCreatine
  16. Effect of creatine supplementation during resistance training on lean tissue mass and muscular strength in older adults: a meta-analysis.
    Chilibeck PD; Kaviani M; Candow DG; Zello GA · Open access journal of sports medicine · 2020
    Meta-analysis721 participants22 studies pooledAnti-Aging Muscle Gain forCreatine
  17. Changes in Fat Mass Following Creatine Supplementation and Resistance Training in Adults ≥50 Years of Age: A Meta-Analysis.
    Forbes SC; Candow DG; Krentz JR; Roberts MD; Young KC · Journal of functional morphology and kinesiology · 2021
    Meta-analysis609 participants19 studies pooledAnti-Aging Weight Loss forCreatine
  18. Creatine supplementation improves muscular performance in older men.
    Gotshalk LA; Volek JS; Staron RS; Denegar CR; Hagerman FC; Kraemer WJ · Medicine and science in sports and exercise · 2002
    Randomized trial18 participantsAnti-Aging forCreatine
  19. One-carbon metabolism-related compounds are associated with epigenetic aging biomarkers: results from the cross-sectional National Health and Nutrition Examination Survey 1999-2002.
    Bozack AK; Khodasevich D; Nwanaji-Enwerem JC; Gladish N; Shen H; Daredia S; Gamble M; Needham BL; Rehkopf DH; Cardenas A · The American journal of clinical nutrition · 2025
    Cross-sectional study2,346 participantsAnti-Aging forFolate
  20. Longitudinal associations of one-carbon metabolism biomarkers with biological and epigenetic aging in older adults in India.
    Wang J; Crimmins E; Kim JK; Chang NS; Dey S; Lee J; Thyagarajan B; Vivek S · GeroScience · 2026
    Cohort studyAnti-Aging forFolate
  21. Associations between leukocyte telomere length and three measures of folate status: a cross-sectional analysis of NHANES 1999-2002.
    Xue Q; Chen H · Frontiers in nutrition · 2026
    Cross-sectional study7,324 participantsAnti-Aging forFolate
  22. Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging.
    Kado DM; Karlamangla AS; Huang MH; Troen A; Rowe JW; Selhub J; Seeman TE · The American journal of medicine · 2005
    Cohort study499 participantsAnti-Aging forFolate
  23. Blood folate is associated with asymptomatic or partially symptomatic Alzheimer's disease in the Nun study.
    Wang H; Odegaard A; Thyagarajan B; Hayes J; Cruz KS; Derosiers MF; Tyas SL; Gross MD · Journal of Alzheimer's disease : JAD · 2012
    Cohort study60 participantsAnti-Aging forFolate
  24. Taurine supplementation reduces myeloperoxidase and matrix-metalloproteinase-9 levels and improves the effects of exercise in cognition and physical fitness in older women.
    Chupel MU; Minuzzi LG; Furtado GE; Santos ML; Ferreira JP; Filaire E; Teixeira AM · Amino acids · 2021
    Randomized trial48 participantsAnti-Aging forTaurine
  25. Taurine as a possible antiaging therapy: A controlled clinical trial on taurine antioxidant activity in women ages 55 to 70.
    Abud GF; De Carvalho FG; Batitucci G; Travieso SG; Bueno Junior CR; Barbosa Junior F; Marchini JS; de Freitas EC · Nutrition (Burbank, Los Angeles County, Calif.) · 2022
    Randomized trial24 participantsAnti-Aging forTaurine
  26. Association of taurine intake with changes in physical fitness among community-dwelling middle-aged and older Japanese adults: an 8-year longitudinal study.
    Domoto T; Kise K; Oyama Y; Furuya K; Kato Y; Nishita Y; Kozakai R; Otsuka R · Frontiers in nutrition · 2024
    Cohort studyAnti-Aging forTaurine
  27. Oral creatine monohydrate supplementation improves brain performance: a double-blind, placebo-controlled, cross-over trial.
    Rae C; Digney AL; McEwan SR; Bates TC · Proceedings. Biological sciences · 2003
    Randomized trial45 participantsBrain Health forCreatine
  28. Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG.
    Hersch SM; Gevorkian S; Marder K; Moskowitz C; Feigin A; Cox M; Como P; Zimmerman C; Lin M; Zhang L; Ulug AM; Beal MF; Matson W; Bogdanov M; Ebbel E; Zaleta A; Kaneko Y; Jenkins B; Hevelone N; Zhang H; Yu H; Schoenfeld D; Ferrante R; Rosas HD · Neurology · 2006
    Randomized trial64 participantsBrain Health forCreatine
  29. Creatine supplementation and cognitive performance in elderly individuals.
    McMorris T; Mielcarz G; Harris RC; Swain JP; Howard A · Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2008
    Randomized trial32 participantsBrain Health Productivity Boost forCreatine
  30. Effects of high-load, velocity-intentional variable resistance training combined with creatine supplementation on neuroplasticity, oxidative stress, inflammation, physical function, cognitive performance and quality of life in older adults: A randomized, double-blind, placebo-controlled trial.
    Fernandez-Garrido J; Martin EG; Saez-Berlanga A; Gargallo-Bayo P; Gene-Morales J; Alix-Fages C; Jiménez-Martínez P; Caballero O; Salvador-Palmer R; Colado JC · Experimental gerontology · 2026
    Randomized trial103 participantsBrain Health General Health forCreatine
  31. Single-Dose Creatine Reduces Sleep Deprivation-Induced Deterioration in Cognitive Performance.
    Gordji-Nejad A; Matusch A; Hengstler L; Beer S; Kroll T; Klein S; Elmenhorst D; Bauer A; Drzezga A · Nutrients · 2026
    Randomized trial29 participantsBrain Health forCreatine
  32. B vitamins and prevention of cognitive decline and incident dementia: a systematic review and meta-analysis.
    Wang Z; Zhu W; Xing Y; Jia J; Tang Y · Nutrition reviews · 2022
    Meta-analysis46,175 participants95 studies pooledBrain Health Cognitive Support forFolate
  33. Folate and long-chain polyunsaturated fatty acid supplementation during pregnancy has long-term effects on the attention system of 8.5-y-old offspring: a randomized controlled trial.
    Catena A; Muñoz-Machicao JA; Torres-Espínola FJ; Martínez-Zaldívar C; Diaz-Piedra C; Gil A; Haile G; Györei E; Molloy AM; Decsi T; Koletzko B; Campoy C · The American journal of clinical nutrition · 2016
    Randomized trial136 participantsBrain Health Mental Focus forFolate
  34. Folic acid supplementation improves cognitive function in participants with cerebral small vascular disease-related cognitive impairment: a randomized controlled trial.
    Liu Y; Yu Z; Cai Z; Zhao L; Wang Y; Guo Y; Su X; Miao Y; Yi B; Wang Y; Zhang X · The journal of prevention of Alzheimer's disease · 2025
    Randomized trial220 participantsBrain Health forFolate
  35. Circulating folate concentrations and the risk of mild cognitive impairment: A prospective study on the older Chinese population without folic acid fortification.
    Fu J; Liu Q; Zhu Y; Sun C; Duan H; Huang L; Zhou D; Wang Z; Zhao J; Li Z; Ma F; Li W; Liu H; Zhang X; Chen Y; Wang G; Du Y; Huang G · European journal of neurology · 2022
    Cohort study3,974 participantsBrain Health forFolate
  36. Normal-But-Low Serum Folate Levels and the Risks for Cognitive Impairment.
    Jang S; Han JW; Shin J; Kim TH; Kwak KP; Kim K; Kim BJ; Kim SG; Kim JL; Kim TH; Moon SW; Park JY; Park JH; Byun S; Suh SW; Seo J; So Y; Ryu SH; Youn JC; Lee KH; Lee DY; Lee DW; Lee SB; Lee JJ; Lee JR; Jeong H; Jeong HG; Jhoo JH; Han K; Hong JW; Kim KW · Psychiatry investigation · 2020
    Cohort study3,910 participantsBrain Health forFolate
  37. Combined L-carnosine and L-tyrosine supplementation as an ergogenic strategy for physical and cognitive performance under fatigue in professional football players.
    Bilgin S; Bozyılan E; Buzdağlı Y; Karaç Öcal Y; Gürkan O; Toktaş S; İnan H; Egil İ; Yarayan YE · Frontiers in nutrition · 2026
    Randomized trial24 participantsBrain Health forTyrosine
  38. Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands--A review.
    Jongkees BJ; Hommel B; Kühn S; Colzato LS · Journal of psychiatric research · 2016
    Narrative reviewBrain Health forTyrosine
  39. Influence of nutritional tyrosine on cognition and functional connectivity in healthy old humans.
    Hensel C; Becker M; Düzel S; Demuth I; Norman K; Steinhagen-Thiessen E; Gallinat J; Lindenberger U; Kühn S · NeuroImage · 2019
    Cross-sectional study286 participantsBrain Health forTyrosine
  40. Dietary Tyrosine Intake (FFQ) Is Associated with Locus Coeruleus, Attention and Grey Matter Maintenance: An MRI Structural Study on 398 Healthy Individuals of the Berlin Aging Study-II.
    Plini ERG; Melnychuk MC; Harkin A; Dahl MJ; McAuslan M; Kühn S; Boyle RT; Whelan R; Andrews R; Düzel S; Drewelies J; Wagner GG; Lindenberger U; Norman K; Robertson IH; Dockree PM · The journal of nutrition, health & aging · 2023
    Cross-sectional study398 participantsBrain Health forTyrosine
  41. Baseline-dependent effect of dopamine's precursor L-tyrosine on working memory gating but not updating.
    Jongkees BJ · Cognitive, affective & behavioral neuroscience · 2021
    Randomized trial45 participantsBrain Health forTyrosine
  42. Associations of dietary folate, vitamin B6 and B12 intake with cardiovascular outcomes in 115664 participants: a large UK population-based cohort.
    Zhang B; Dong H; Xu Y; Xu D; Sun H; Han L · European journal of clinical nutrition · 2023
    Cohort study115,664 participantsCardiovascular Support forFolate
  43. Folate, Homocysteine, and Adverse Outcomes After Ischemic Stroke.
    Shi M; Zheng J; Liu Y; Mao X; Wu X; Chu M; Niu H; Sun L; Chang X; He Y; Liu Y; Guo D; Zhang Y; Zhu Z; Zhao J · Journal of the American Heart Association · 2024
    Cohort study3,530 participantsCardiovascular Support forFolate
  44. Effect of folic acid on endothelial function following acute myocardial infarction.
    Moens AL; Claeys MJ; Wuyts FL; Goovaerts I; Van Hertbruggen E; Wendelen LC; Van Hoof VO; Vrints CJ · The American journal of cardiology · 2007
    Randomized trial40 participantsCardiovascular Support forFolate
  45. Folic acid enhances endothelial function and reduces blood pressure in smokers: a randomized controlled trial.
    Mangoni AA; Sherwood RA; Swift CG; Jackson SH · Journal of internal medicine · 2003
    Randomized trial24 participantsCardiovascular Support forFolate
  46. 5-methyltetrahydrofolate, the active form of folic acid, restores endothelial function in familial hypercholesterolemia.
    Verhaar MC; Wever RM; Kastelein JJ; van Dam T; Koomans HA; Rabelink TJ · Circulation · 1998
    Non-randomized trial20 participantsCardiovascular Support forFolate
  47. Taurine Supplementation Lowers Blood Pressure and Improves Vascular Function in Prehypertension: Randomized, Double-Blind, Placebo-Controlled Study.
    Sun Q; Wang B; Li Y; Sun F; Li P; Xia W; Zhou X; Li Q; Wang X; Chen J; Zeng X; Zhao Z; He H; Liu D; Zhu Z · Hypertension (Dallas, Tex. : 1979) · 2016
    Randomized trial120 participantsCardiovascular Support forTaurine
  48. Taurine ameliorates blood pressure and vascular function in patients with type 2 diabetes: Randomized, double-blind, placebo-controlled trial.
    Li Y; Wang Q; Liu Y; Li Q; Xia W; Lin S; Yang Q; Scholze A; Zhao Z; He H; Zhang H; Yan Z; Tepel M; Mu H; Zhu Z; Liu D · iScience · 2025
    Randomized trial165 participantsCardiovascular Support forTaurine
  49. Taurine reduces the risk for metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials.
    Tzang CC; Chi LY; Lin LH; Lin TY; Chang KV; Wu WT; Özçakar L · Nutrition & diabetes · 2024
    Meta-analysis1,024 participants25 studies pooledCardiovascular Support forTaurine
  50. Effects of Oral Taurine Supplementation on Cardiometabolic Risk Factors: A Meta-analysis and Systematic Review of Randomized Clinical Trials.
    Nie Z; Liu Y; Zhang M; Wu C; Cao Q; Xu J; Zheng Y; Min Z; Zhang W; Han S · Nutrition reviews · 2025
    Meta-analysis34 studies pooledCardiovascular Support General Health forTaurine
  51. The effects of taurine supplementation on glycemic control and serum lipid profile in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial.
    Maleki V; Alizadeh M; Esmaeili F; Mahdavi R · Amino acids · 2021
    Randomized trial45 participantsCardiovascular Support forTaurine
  52. Effects of Creatine Monohydrate Loading on Sleep Metrics, Physical Performance, Cognitive Function, and Recovery in Physically Active Men: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial.
    Ben Maaoui K; Delleli S; Mahdi N; Jebabli A; Del Coso J; Chtourou H; Ardigò LP; Ouergui I · Nutrients · 2025
    Randomized trial14 participantsCognitive Support forCreatine
  53. Creatine supplementation enhances corticomotor excitability and cognitive performance during oxygen deprivation.
    Turner CE; Byblow WD; Gant N · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015
    Randomized trial15 participantsCognitive Support Productivity Boost forCreatine
  54. The effects of creatine supplementation on cognitive performance-a randomised controlled study.
    Sandkühler JF; Kersting X; Faust A; Königs EK; Altman G; Ettinger U; Lux S; Philipsen A; Müller H; Brauner J · BMC medicine · 2023
    Randomized trial123 participantsCognitive Support Productivity Boost forCreatine
  55. Acute creatine supplementation enhances technical performance in adolescent basketball players under cognitive-motor dual-task condition.
    Wu J; Qiu P; Li Y · Journal of the International Society of Sports Nutrition · 2025
    Randomized trial40 participantsCognitive Support forCreatine
  56. Effects of creatine supplementation on memory in healthy individuals: a systematic review and meta-analysis of randomized controlled trials.
    Prokopidis K; Giannos P; Triantafyllidis KK; Kechagias KS; Forbes SC; Candow DG · Nutrition reviews · 2023
    Meta-analysis225 participants10 studies pooledCognitive Support forCreatine
  57. Effects of 6-Month Folic Acid Supplementation on Cognitive Function and Blood Biomarkers in Mild Cognitive Impairment: A Randomized Controlled Trial in China.
    Ma F; Wu T; Zhao J; Han F; Marseglia A; Liu H; Huang G · The journals of gerontology. Series A, Biological sciences and medical sciences · 2017
    Randomized trial180 participantsCognitive Support forFolate
  58. Serum folate and B12 levels in association with cognitive impairment among seniors: results from the VELESTINO study in Greece and meta-analysis.
    Michelakos T; Kousoulis AA; Katsiardanis K; Dessypris N; Anastasiou A; Katsiardani KP; Kanavidis P; Stefanadis C; Papadopoulos FC; Petridou ET · Journal of aging and health · 2013
    Meta-analysis8,122 participants9 studies pooledCognitive Support forFolate
  59. Homocysteine and folate as risk factors for dementia and Alzheimer disease.
    Ravaglia G; Forti P; Maioli F; Martelli M; Servadei L; Brunetti N; Porcellini E; Licastro F · The American journal of clinical nutrition · 2005
    Cohort study816 participantsCognitive Support forFolate
  60. Folate mediates cognitive impairment of aged people with periodontitis.
    Liu F; Liu Y; Feng Y; Zhao J; Wang M; Ye M; Zhang Y; Gan X; Pan Q; Shen J · Nutritional neuroscience · 2025
    Cross-sectional study1,966 participantsCognitive Support forFolate
  61. Dietary amino acid taurine ameliorates liver injury in chronic hepatitis patients.
    Hu YH; Lin CL; Huang YW; Liu PE; Hwang DF · Amino acids · 2008
    Non-randomized trial24 participantsDetoxification forTaurine
  62. Taurine status and response to intravenous taurine supplementation in adults with short-bowel syndrome undergoing long-term parenteral nutrition: a pilot study.
    Schneider SM; Joly F; Gehrardt MF; Badran AM; Myara A; Thuillier F; Coudray-Lucas C; Cynober L; Trivin F; Messing B · The British journal of nutrition · 2006
    Single-arm trial32 participantsDetoxification forTaurine
  63. Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine.
    Haskell CF; Kennedy DO; Wesnes KA; Scholey AB · Psychopharmacology · 2005
    Randomized trial48 participantsEnergy forCaffeine
  64. Caffeine-containing energy drink improves physical performance of elite rugby players during a simulated match.
    Del Coso J; Ramírez JA; Muñoz G; Portillo J; Gonzalez-Millán C; Muñoz V; Barbero-Álvarez JC; Muñoz-Guerra J · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2016
    Randomized trial26 participantsEnergy forCaffeine
  65. Differential cognitive effects of energy drink ingredients: caffeine, taurine, and glucose.
    Giles GE; Mahoney CR; Brunyé TT; Gardony AL; Taylor HA; Kanarek RB · Pharmacology, biochemistry, and behavior · 2013
    Randomized trial48 participantsEnergy forCaffeine
  66. Does Single or Combined Caffeine and Taurine Supplementation Improve Athletic and Cognitive Performance without Affecting Fatigue Level in Elite Boxers? A Double-Blind, Placebo-Controlled Study.
    Ozan M; Buzdagli Y; Eyipinar CD; Baygutalp NK; Yüce N; Oget F; Kan E; Baygutalp F · Nutrients · 2022
    Randomized trial20 participantsEnergy forCaffeine
  67. Trait Energy and Fatigue Modify the Effects of Caffeine on Mood, Cognitive and Fine-Motor Task Performance: A Post-Hoc Study.
    Fuller DT; Smith ML; Boolani A · Nutrients · 2021
    Randomized trialEnergy forCaffeine
  68. Synergistic effects of creatine, carbs, protein on repeated sprint performance.
    Wang Y; Wei H; Cheng X; Chen Z · Scientific reports · 2026
    Randomized trial60 participantsEnergy forCreatine
  69. The Effects of Creatine Monohydrate Supplementation on Recovery from Eccentric Exercise-Induced Muscle Damage: A Double-Blind, Randomized, Placebo-Controlled Trial Considering Sex and Age Differences.
    Yamaguchi S; Inami T; Nishioka T; Morito A; Ishiyama K; Murayama M · Nutrients · 2025
    Randomized trial40 participantsEnergy forCreatine
  70. The Effect of Prior Creatine Intake for 28 Days on Accelerated Recovery from Exercise-Induced Muscle Damage: A Double-Blind, Randomized, Placebo-Controlled Trial.
    Yamaguchi S; Inami T; Ishida H; Morito A; Yamada S; Nagata N; Murayama M · Nutrients · 2024
    Randomized trial20 participantsEnergy forCreatine
  71. Creatine supplementation attenuates the rate of fatigue development during intermittent isometric exercise performed above end-test torque.
    Abdalla LHP; Broxterman RM; Greco CC; Denadai BS · Experimental physiology · 2021
    Randomized trial16 participantsEnergy forCreatine
  72. The effect of continuous low dose creatine supplementation on force, power, and total work.
    Burke DG; Silver S; Holt LE; Smith Palmer T; Culligan CJ; Chilibeck PD · International journal of sport nutrition and exercise metabolism · 2000
    Randomized trial41 participantsEnergy forCreatine
  73. Effects of Caffeine Intake on Endurance Running Performance and Time to Exhaustion: A Systematic Review and Meta-Analysis.
    Wang Z; Qiu B; Gao J; Del Coso J · Nutrients · 2023
    Meta-analysis254 participants21 studies pooledFitness forCaffeine
  74. Sex Differences in the Ergogenic Response of Acute Caffeine Intake on Muscular Strength, Power and Endurance Performance in Resistance-Trained Individuals: A Randomized Controlled Trial.
    Montalvo-Alonso JJ; Ferragut C; Del Val-Manzano M; Valadés D; Roberts J; Pérez-López A · Nutrients · 2024
    Randomized trial76 participantsFitness forCaffeine
  75. Effect of creatine and weight training on muscle creatine and performance in vegetarians.
    Burke DG; Chilibeck PD; Parise G; Candow DG; Mahoney D; Tarnopolsky M · Medicine and science in sports and exercise · 2004
    Randomized trial42 participantsFitness forCreatine
  76. Effects of Combined Versus Single Supplementation of Creatine, Beta-Alanine, and L-Citrulline During Short Sprint Interval Training on Basketball Players' Performance: A Double-Blind Randomized Placebo-Controlled Trial.
    Li M; Sheykhlouvand M · International journal of sports physiology and performance · 2025
    Randomized trial48 participantsFitness forCreatine
  77. The Additive Effects of Creatine Supplementation and Exercise Training in an Aging Population: A Systematic Review of Randomized Controlled Trials.
    Stares A; Bains M · Journal of geriatric physical therapy (2001) · 2021
    Systematic review17 studies pooledFitness forCreatine
  78. Taurine supplementation enhances anaerobic power in elite speed skaters: A double-blind, randomized, placebo-controlled, crossover study.
    Buzdağlı Y; Eyipınar CD; Öget F; Şıktar E; Forbes SC; Tekin A · Biology of sport · 2023
    Randomized trial30 participantsFitness forTaurine
  79. The effect of acute taurine ingestion on 3-km running performance in trained middle-distance runners.
    Balshaw TG; Bampouras TM; Barry TJ; Sparks SA · Amino acids · 2013
    Randomized trial8 participantsFitness forTaurine
  80. The impact of creatine supplementation associated with resistance training on muscular strength and lean tissue mass in the aged: a systematic review and meta-analysis.
    Liu S; Huang N; Wu W; OuYang X; Luo Y; Zhong Y; Wang M; Xiao L · European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
    Meta-analysis482 participants8 studies pooledGeneral Health forCreatine
  81. Creatine supplementation during pulmonary rehabilitation in chronic obstructive pulmonary disease.
    Fuld JP; Kilduff LP; Neder JA; Pitsiladis Y; Lean ME; Ward SA; Cotton MM · Thorax · 2005
    Randomized trial38 participantsGeneral Health forCreatine
  82. A multi-metabolite signature robustly predicts long-term mortality in the PREDIMED trial and several US cohorts.
    Fernández-Duval G; Razquin C; Wang F; Yun H; Hu J; Guasch-Ferré M; Rexrode K; Balasubramanian R; García-Gavilán J; Ruiz-Canela M; Clish CB; Corella D; Gómez-Gracia E; Fiol M; Estruch R; Lapetra J; Fitó M; Serra-Majem L; Ros E; Liang L; Dennis C; Asensio EM; Castañer O; Planes FJ; Salas-Salvadó J; Hu FB; Toledo E; Martínez-González MA · Metabolism: clinical and experimental · 2025
    Cohort study1,878 participantsGeneral Health forCreatine
  83. Plasma creatine, estimated intramuscular creatine, transcellular gradient and the risk of mortality: Results from the PREVEND study.
    Doorenbos CSE; Post A; Stegmann ME; Franssen CFM; Dullaart RPF; Navis G; Connelly MA; Bakker SJL · European journal of clinical investigation · 2026
    Cohort study5,127 participantsGeneral Health forCreatine
  84. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsGeneral Health forFolate
  85. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsGeneral Health forFolate
  86. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsGeneral Health forFolate
  87. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewGeneral Health forFolate
  88. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledGeneral Health forFolate
  89. Cognitive Effects of Taurine and Related Sulphur-Containing Amino Acids: A Systematic Review of Human Trials and Considerations for Plant-Based Dietary Transitions.
    Moore JA; Cousins AL; Taylor RMJ; Griffiths AR; Young HA · Foods (Basel, Switzerland) · 2026
    Systematic review244 participants8 studies pooledGeneral Health forTaurine
  90. Association between habitual dietary taurine intake and the risk of metabolic dysfunction-associated steatotic liver disease: a prospective cohort study.
    Zhang S; Xu X; Wang D; Gu Y; Wu H; Meng G; Zhang Q; Liu L; Borné Y; Niu K; Bai L · Food & function · 2026
    Cohort study16,699 participantsGeneral Health forTaurine
  91. Effects of modafinil and caffeine on night-time vigilance of air force crewmembers: A randomized controlled trial.
    Wingelaar-Jagt YQ; Bottenheft C; Riedel WJ; Ramaekers JG · Journal of psychopharmacology (Oxford, England) · 2023
    Randomized trial32 participantsMental Focus forCaffeine
  92. Acute effects of caffeine on attention: a comparison of non-consumers and withdrawn consumers.
    Smith AP; Christopher G; Sutherland D · Journal of psychopharmacology (Oxford, England) · 2013
    Randomized trial70 participantsMental Focus forCaffeine
  93. Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.
    Wesensten NJ; Killgore WD; Balkin TJ · Journal of sleep research · 2006
    Randomized trial48 participantsMental Focus forCaffeine
  94. Effects of caffeine on mood and performance: a study of realistic consumption.
    Brice CF; Smith AP · Psychopharmacology · 2003
    Clinical trial24 participantsMental Focus forCaffeine
  95. Effects of caffeine or diphenhydramine on visual vigilance.
    Fine BJ; Kobrick JL; Lieberman HR; Marlowe B; Riley RH; Tharion WJ · Psychopharmacology · 1995
    Randomized trial24 participantsMental Focus forCaffeine
  96. Cerebral folate receptor autoantibodies in autism spectrum disorder.
    Frye RE; Sequeira JM; Quadros EV; James SJ; Rossignol DA · Molecular psychiatry · 2014
    Non-randomized trial93 participantsMental Focus forFolate
  97. Folate, vitamin B-12, and cognitive function in the Boston Puerto Rican Health Study.
    Boumenna T; Scott TM; Lee JS; Palacios N; Tucker KL · The American journal of clinical nutrition · 2026
    Cross-sectional study1,408 participantsMental Focus forFolate
  98. Vitamins B9 and B12 in children with attention deficit hyperactivity disorder (ADHD).
    Razavinia F; Ebrahimiyan A; Faal Siahkal S; Ghazinezhad N; Abedi P · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2024
    Meta-analysis982 participants6 studies pooledMental Focus forFolate
  99. Does L-Methylfolate Supplement Methylphenidate Pharmacotherapy in Attention-Deficit/Hyperactivity Disorder?: Evidence of Lack of Benefit From a Double-Blind, Placebo-Controlled, Randomized Clinical Trial.
    Surman C; Ceranoglu A; Vaudreuil C; Albright B; Uchida M; Yule A; Spencer A; Boland H; Grossman R; Rhodewalt L; Fitzgerald M; Biederman J · Journal of clinical psychopharmacology · 2019
    Randomized trial44 participantsMental Focus forFolate
  100. Vitamin B-6 supplementation in elderly men: effects on mood, memory, performance and mental effort.
    Deijen JB; van der Beek EJ; Orlebeke JF; van den Berg H · Psychopharmacology · 1995
    Randomized trial76 participantsMental Focus forVitamin B6
  101. The effect of vitamin B6 on cognition.
    Malouf R; Grimley Evans J · The Cochrane database of systematic reviews · 2004
    Systematic review109 participants2 studies pooledMental Focus forVitamin B6
  102. Antiemetic use during pregnancy and child neurodevelopment: population-based birth cohort study.
    Cho Y; Choi EY; Han JY; Kim H; Choe YJ; Shin JY · BMC medicine · 2025
    Cohort study630,904 participantsMental Focus forVitamin B6
  103. A nutritional blend of taurine, vitamins B6, B9, and B12 improves motivated behaviors in healthy adults-a double-blinded randomized clinical trial.
    Anlacan VM; Jamora RDG; Krattinger LF; De Longis E; Hartweg M; Steinmann M; Trovò L · Frontiers in nutrition · 2026
    Randomized trial44 participantsMental Focus forVitamin B6
  104. B-Vitamin Therapy for Kidney Transplant Recipients Lowers Homocysteine and Improves Selective Cognitive Outcomes in the Randomized FAVORIT Ancillary Cognitive Trial
    Tammy M Scott, Graham Rogers, Daniel E Weiner, Kathryn Livingston, Jacob Selhub, Paul F Jacques, Irwin H Rosenberg, Aron M Troen · The Journal of Prevention of Alzheimer's Disease · 2017
    Randomized trial584 participantsMental Focus forVitamin B6
  105. A Randomized Study to Examine the Ability of a Caffeine-Based Energy Drink to Impact Energy Expenditure, Fat Oxidation, and Cognitive Performance.
    Krieger J; Schrautemeier A; Hagele A; Gaige C; Mennemeyer O; Tolbert S; Iannotti J; Kerksick C; Noonan C; Mumford P · Nutrients · 2025
    Randomized trial60 participantsMetabolism Boost forCaffeine
  106. Oolong tea increases metabolic rate and fat oxidation in men.
    Rumpler W; Seale J; Clevidence B; Judd J; Wiley E; Yamamoto S; Komatsu T; Sawaki T; Ishikura Y; Hosoda K · The Journal of nutrition · 2001
    Randomized trial12 participantsMetabolism Boost forCaffeine
  107. Effect of caffeine intake on fat oxidation rate during exercise: is there a dose-response effect?
    Gutiérrez-Hellín J; Aguilar-Navarro M; Ruiz-Moreno C; Muñoz A; Varillas-Delgado D; Amaro-Gahete FJ; Del Coso J · European journal of nutrition · 2023
    Randomized trial18 participantsMetabolism Boost forCaffeine
  108. Comparison of changes in energy expenditure and body temperatures after caffeine consumption.
    Koot P; Deurenberg P · Annals of nutrition & metabolism · 1995
    Randomized trial12 participantsMetabolism Boost forCaffeine
  109. Caffeine Increases Work Done above Critical Power, but Not Anaerobic Work.
    Silveira R; Andrade-Souza VA; Arcoverde L; Tomazini F; Sansonio A; Bishop DJ; Bertuzzi R; Lima-Silva AE · Medicine and science in sports and exercise · 2018
    Randomized trial9 participantsMetabolism Boost forCaffeine
  110. Creatine target engagement with brain bioenergetics: a dose-ranging phosphorus-31 magnetic resonance spectroscopy study of adolescent females with SSRI-resistant depression.
    Kondo DG; Forrest LN; Shi X; Sung YH; Hellem TL; Huber RS; Renshaw PF · Amino acids · 2017
    Randomized trialMetabolism Boost forCreatine
  111. Creatine supplementation and glycemic control: a systematic review.
    Pinto CL; Botelho PB; Pimentel GD; Campos-Ferraz PL; Mota JF · Amino acids · 2017
    Systematic reviewMetabolism Boost forCreatine
  112. The effect of dietary creatine supplementation on skeletal muscle metabolism in congestive heart failure.
    Andrews R; Greenhaff P; Curtis S; Perry A; Cowley AJ · European heart journal · 1998
    Clinical trialMetabolism Boost forCreatine
  113. A comprehensive review of the physiology and evidence base to guide the use of ergogenic and medical supplements for enhanced cycling performance.
    Rowland A; Edwards S; Prieto-Bellver G; Menz B; Rowland A; Cornelisse E; Karapetis CS; Wallen MP; Hopkins AM · Journal of the International Society of Sports Nutrition · 2026
    Narrative reviewMetabolism Boost forCreatine
  114. Creatine Supplementation Beyond Athletics: Benefits of Different Types of Creatine for Women, Vegans, and Clinical Populations-A Narrative Review.
    Gutiérrez-Hellín J; Del Coso J; Franco-Andrés A; Gamonales JM; Espada MC; González-García J; López-Moreno M; Varillas-Delgado D · Nutrients · 2025
    Narrative reviewMetabolism Boost forCreatine
  115. Taurine supplementation as a therapeutic strategy for cellular senescence and chronic inflammation in long COVID: a systematic review and meta-analysis.
    Wang K; Ma CH; Khoramjoo M; Kung JY; Oudit GY · BMC infectious diseases · 2026
    Meta-analysis1,030 participants27 studies pooledMetabolism Boost forTaurine
  116. Effect of Long-Term Taurine Supplementation on the Lipid and Glycaemic Profile in Adults with Overweight or Obesity: A Systematic Review and Meta-Analysis.
    Sun Q; Wang J; Wang H; Yu H; Wan K; Ma F; Wang R · Nutrients · 2025
    Meta-analysis9 studies pooledMetabolism Boost forTaurine
  117. The effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trials.
    Guan L; Miao P · European journal of pharmacology · 2021
    Meta-analysis12 studies pooledMetabolism Boost forTaurine
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    Zhang M; Bi LF; Fang JH; Su XL; Da GL; Kuwamori T; Kagamimori S · Amino acids · 2005
    Randomized trial30 participantsMetabolism Boost forTaurine
  119. Use of skeletal muscle fiber composition to assess relationship between amino acid metabolism and insulin sensitivity.
    Magnusson TE; Blackwood SJ; Tischer D; Strmeň T; Pontén M; Edman S; Horwath O; Apró W; Moberg M; Chorell E; Katz A · European journal of endocrinology · 2025
    Cross-sectional study36 participantsMetabolism Boost forTaurine
  120. Effects of Acute Ingestion of Caffeine Capsules on Muscle Strength and Muscle Endurance: A Systematic Review and Meta-Analysis.
    Wu W; Chen Z; Zhou H; Wang L; Li X; Lv Y; Sun T; Yu L · Nutrients · 2024
    Meta-analysis14 studies pooledMuscle Gain forCaffeine
  121. Acute caffeine intake improves muscular strength, power, and endurance performance, reversing the time-of-day effect regardless of muscle activation level in resistance-trained males: a randomized controlled trial.
    Montalvo-Alonso JJ; Del Val-Manzano M; Cerezo-Telléz E; Ferragut C; Valadés D; Rodríguez-Falces J; Pérez-López A · European journal of applied physiology · 2025
    Randomized trial13 participantsMuscle Gain forCaffeine
  122. Wake up and smell the coffee: caffeine supplementation and exercise performance-an umbrella review of 21 published meta-analyses.
    Grgic J; Grgic I; Pickering C; Schoenfeld BJ; Bishop DJ; Pedisic Z · British journal of sports medicine · 2020
    Systematic review21 studies pooledMuscle Gain forCaffeine
  123. Effects of caffeine intake on muscle strength and power: a systematic review and meta-analysis.
    Grgic J; Trexler ET; Lazinica B; Pedisic Z · Journal of the International Society of Sports Nutrition · 2018
    Meta-analysis20 studies pooledMuscle Gain forCaffeine
  124. Caffeine increases strength and power performance in resistance-trained females during early follicular phase.
    Norum M; Risvang LC; Bjørnsen T; Dimitriou L; Rønning PO; Bjørgen M; Raastad T · Scandinavian journal of medicine & science in sports · 2021
    Randomized trial15 participantsMuscle Gain forCaffeine
  125. The Effect of Creatine Supplementation on Resistance Training-Based Changes to Body Composition: A Systematic Review and Meta-analysis.
    Desai I; Wewege MA; Jones MD; Clifford BK; Pandit A; Kaakoush NO; Simar D; Hagstrom AD · Journal of strength and conditioning research · 2025
    Meta-analysis362 participants12 studies pooledMuscle Gain Weight Loss forCreatine
  126. Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults <50 Years of Age: A Systematic Review and Meta-Analysis.
    Wang Z; Qiu B; Li R; Han Y; Petersen C; Liu S; Zhang Y; Liu C; Candow DG; Del Coso J · Nutrients · 2024
    Meta-analysis509 participants23 studies pooledMuscle Gain forCreatine
  127. Comparative Effects of Dietary Protein, Creatine, and Omega-3 Supplementation on Muscle Strength, Endurance, and Recovery in Trained Athletes: A Systematic Review and Network Meta-Analysis.
    Wang Z; Qin G; Kim BM · Nutrients · 2026
    Meta-analysis1,211 participants35 studies pooledMuscle Gain forCreatine
  128. Effects of caffeine on alertness.
    Zwyghuizen-Doorenbos A; Roehrs TA; Lipschutz L; Timms V; Roth T · Psychopharmacology · 1990
    Randomized trial24 participantsProductivity Boost forCaffeine
  129. Effects of Different Sources of Low-Dose Caffeine on Mood/Arousal and Cognitive Performance.
    Irwin C; McCartney D; Grant G; Delang N; Bartrim K; Cox GR; Desbrow B · Perceptual and motor skills · 2023
    Randomized trial22 participantsProductivity Boost forCaffeine
  130. Effects of caffeine, sleep loss, and stress on cognitive performance and mood during U.S. Navy SEAL training. Sea-Air-Land.
    Lieberman HR; Tharion WJ; Shukitt-Hale B; Speckman KL; Tulley R · Psychopharmacology · 2003
    Randomized trial68 participantsProductivity Boost forCaffeine
  131. A review of caffeine's effects on cognitive, physical and occupational performance.
    McLellan TM; Caldwell JA; Lieberman HR · Neuroscience and biobehavioral reviews · 2017
    Narrative reviewProductivity Boost forCaffeine
  132. Acute caffeine supplementation as a nutrition-based strategy to mitigate sleep-loss-related cognitive and operational performance impairments in military personnel: a systematic review and meta-analysis.
    Wang R; Wang W; Meng L; Hao G; Gu G · Frontiers in nutrition · 2026
    Meta-analysis7 studies pooledProductivity Boost forCaffeine
  133. Single dose creatine improves cognitive performance and induces changes in cerebral high energy phosphates during sleep deprivation.
    Gordji-Nejad A; Matusch A; Kleedörfer S; Jayeshkumar Patel H; Drzezga A; Elmenhorst D; Binkofski F; Bauer A · Scientific reports · 2024
    Randomized trialProductivity Boost forCreatine
  134. Dietary supplementation of creatine monohydrate reduces the human fMRI BOLD signal.
    Hammett ST; Wall MB; Edwards TC; Smith AT · Neuroscience letters · 2010
    Non-randomized trialProductivity Boost forCreatine
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    Hoffman J; Ratamess N; Kang J; Mangine G; Faigenbaum A; Stout J · International journal of sport nutrition and exercise metabolism · 2006
    Randomized trial33 participantsTestosterone Support forCreatine
  136. Long-Term Effect of Combination of Creatine Monohydrate Plus β-Hydroxy β-Methylbutyrate (HMB) on Exercise-Induced Muscle Damage and Anabolic/Catabolic Hormones in Elite Male Endurance Athletes.
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    Randomized trial28 participantsTestosterone Support forCreatine
  137. Does creatine cause hair loss? A 12-week randomized controlled trial.
    Lak M; Forbes SC; Ashtary-Larky D; Dadkhahfar S; Robati RM; Nezakati F; Khajevandi M; Naseri S; Gerafiani A; Haghighat N; Antonio J; Tinsley GM · Journal of the International Society of Sports Nutrition · 2025
    Randomized trial38 participantsTestosterone Support forCreatine
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    Eijnde BO; Hespel P · Medicine and science in sports and exercise · 2001
    Randomized trial11 participantsTestosterone Support forCreatine
  139. Do "testosterone boosters" really increase serum total testosterone? A systematic review.
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    Systematic review3 studies pooledTestosterone Support forCreatine
  140. Association between coffee intake and skeletal muscle mass among U.S. adults: a population-based study.
    Yin H; Zhu W; Guo L; Li W; Liang M · Frontiers in nutrition · 2024
    Cross-sectional study8,333 participantsWeight Gain forCaffeine
  141. Use of caffeine in 19,660 randomly selected U.S. adults: the role of overweight and obesity.
    Tucker LA; Beltran F · Frontiers in nutrition · 2025
    Cross-sectional study19,660 participantsWeight Gain forCaffeine
  142. Dietary caffeine intake is associated with favorable metabolic profile among apparently healthy overweight and obese individuals.
    Alshahrani SH; Atia YA; Badir RA; Almalki SG; Tayyib NA; Shahab S; Romero-Parra RM; Abid MK; Hussien BM; Ramaiah P · BMC endocrine disorders · 2023
    Cross-sectional study488 participantsWeight Gain forCaffeine
  143. Exploring parental prenatal influences on child health: A multicohort study and data visualisation tool.
    Sharp GC; Lawlor DA; Easey KE; Kundu S; Elhakeem A; Hone E; McEachan RRC; Magnus MC; Havdahl A; Relton CL · PLoS medicine · 2026
    Cohort study232,139 participantsWeight Gain forCaffeine
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    Randomized trial23 participantsWeight Gain forCreatine
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    Meta-analysis100 studies pooledWeight Gain forCreatine
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  150. Oxidative stress and inflammation in obesity after taurine supplementation: a double-blind, placebo-controlled study.
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    Randomized trial24 participantsWeight Gain forTaurine
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  153. Changes in caffeine intake and long-term weight change in men and women.
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  154. Does caffeine ingestion before a short-term sprint interval training promote body fat loss?
    Ferreira GA; Felippe LC; Bertuzzi R; Bishop DJ; Ramos IS; De-Oliveira FR; Lima-Silva AE · Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2020
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  155. Eight Weeks of Sprint Interval Training With Adding Caffeine Ingestion Leads to Greater Improvements in Health-Related Physiological Parameters in Obese Male Adults.
    Zhiang J; Song Q · Physiological research · 2026
    Randomized trial30 participantsWeight Loss forCaffeine
  156. Caffeine treatment prevented from weight regain after calorie shifting diet induced weight loss.
    Davoodi SH; Hajimiresmaiel SJ; Ajami M; Mohseni-Bandpei A; Ayatollahi SA; Dowlatshahi K; Javedan G; Pazoki-Toroudi H · Iranian journal of pharmaceutical research : IJPR · 2014
    Non-randomized trial60 participantsWeight Loss forCaffeine
  157. The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials.
    Tabrizi R; Saneei P; Lankarani KB; Akbari M; Kolahdooz F; Esmaillzadeh A; Nadi-Ravandi S; Mazoochi M; Asemi Z · Critical reviews in food science and nutrition · 2020
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  158. Effects of creatine supplementation with and without exercise and diet intervention on body composition, cognitive function, and markers of health in middle-aged and older adults.
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    Randomized trial64 participantsWeight Loss forCreatine
  159. Creatine supplementation protocols with or without training interventions on body composition: a GRADE-assessed systematic review and dose-response meta-analysis.
    Pashayee-Khamene F; Heidari Z; Asbaghi O; Ashtary-Larky D; Goudarzi K; Forbes SC; Candow DG; Bagheri R; Ghanavati M; Dutheil F · Journal of the International Society of Sports Nutrition · 2024
    Meta-analysis3,655 participants143 studies pooledWeight Loss forCreatine
  160. Effects of Creatine Monohydrate Gummies on Performance and Body Composition in Female Beach Volleyball Athletes.
    Pereira F; Forbes SC; Romano V; Christopher P; Santana JC; Antonio J · Journal of functional morphology and kinesiology · 2026
    Randomized trial32 participantsWeight Loss forCreatine