MegaFolinic 800 mcg
Source Naturals
MegaFolinic 800 mcg
4.9
★ ★ ★ ★ ★
(4409 ratings)
Folate 800 mcg
Score 90.0
An excellent value folate supplement providing a highly bioavailable Folinic Acid form at a potent dose and exceptionally low price, making it a top choice for quality and affordability.
Quantity: 240 Tablet(s)Servings size: 1 Tablet(s) (240 servings)
Selected goals:
Other goals:
General Health
Brain Health
Mood Support
Heart Health
leaderboard Score 90.0
An excellent value folate supplement providing a highly bioavailable Folinic Acid form at a potent dose and exceptionally low price, making it a top choice for quality and affordability.
insights Analysis
Source Naturals MegaFolinic delivers 800mcg of Folinic Acid (Calcium Folinate), a reduced and more bioavailable form of folate that bypasses some initial conversion steps required by synthetic folic acid. This makes it a strong choice for individuals who may have minor MTHFR gene variations or simply prefer a more readily usable form of folate. The product's standout feature is its incredibly low price per serving, which positions it as an outstanding value. Its very high review count further solidifies its reputation for effectiveness and user satisfaction.
- Uses Folinic Acid (Calcium Folinate), a more bioavailable form of folate than synthetic folic acid.
- Provides an excellent and effective dosage of 800mcg.
- Exceptionally low price per serving (4 cents), offering outstanding value.
- Very high review count, indicating strong user satisfaction and perceived effectiveness.
- Not the most active form of folate (methylfolate) for those with severe MTHFR mutations or specific therapeutic needs.
- May still require some metabolic conversion compared to direct methylfolate.
- Potential for tablet size or taste to be a minor issue for some users.
$11.52($0.04 per serving)
 iHerb | $ 11.52 | |
 Vitacost | $ 11.89 | |
 Amazon | $ 12.05 | |
 Pure Formulas | $ 12.59 |
bolt Effectiveness for goals
Yes, adequate folate intake, especially before and during early pregnancy, is highly effective in preventing neural tube defects (NTDs) like spina bifida and anencephaly. This is why many prenatal supplements contain folic acid, the synthetic form of folate. Health organizations recommend women of childbearing age consume sufficient folate daily.
Folate is essential for cell growth and division, DNA synthesis and repair, and red blood cell formation. It plays a crucial role in various metabolic processes, including the metabolism of homocysteine. Many people take folate to support overall health and prevent deficiency.
Folate supplements are very effective in treating and resolving a folate deficiency. Deficiency can lead to megaloblastic anemia, fatigue, and other symptoms. Supplementation typically restores folate levels and alleviates associated symptoms.
Folic acid, the synthetic form found in supplements and fortified foods, is often considered more bioavailable than natural folate from foods. This is because folic acid is more stable and readily absorbed by the body. Once absorbed, both forms are converted to the active form of folate within the body to exert their effects.
Folate is crucial for the formation of red blood cells, which transport oxygen throughout the body, and it's involved in energy metabolism. A deficiency in folate can lead to megaloblastic anemia, causing symptoms like fatigue and low energy. Therefore, ensuring adequate folate intake can support healthy energy levels, especially if a deficiency is present.
schedule Dosage, timing & forms
For most adult men and women, the RDA is 400 micrograms (mcg) of dietary folate equivalents (DFEs) daily. Pregnant individuals are advised to consume 600 mcg DFE daily, and lactating individuals 500 mcg DFE. These recommendations help ensure adequate intake for essential bodily functions.
The two primary forms are folic acid, which is the synthetic form commonly used in fortified foods and supplements, and L-methylfolate (also known as 5-MTHF), which is the active, natural form of folate. Other forms like folinic acid are also available but less common. The choice of form may depend on individual needs or preferences.
Folic acid must be converted by the body into L-methylfolate to become biologically active. L-methylfolate, being the already active form, does not require this conversion. This difference can be significant for individuals with certain genetic variations that affect the conversion process.
Yes, there is an established Tolerable Upper Intake Level (UL) of 1,000 mcg (1 mg) per day for *synthetic folic acid* from supplements and fortified foods for adults. This UL is set because high intakes of folic acid can mask the symptoms of vitamin B12 deficiency. There is no UL established for folate from food sources or for L-methylfolate.
Supplemental dosages vary based on individual needs and health goals, but common doses often range from 400 mcg to 1,000 mcg (1 mg) daily. For specific needs, such as during pregnancy planning, healthcare providers may recommend higher doses of folic acid, often 800 mcg or more. Always consult a healthcare professional for personalized dosage advice.
health_and_safety Safety & interactions
Yes, high doses of Folate, especially folic acid, can mask a Vitamin B12 deficiency. Folate can correct the megaloblastic anemia associated with B12 deficiency, but it does not prevent the irreversible neurological damage that can progress if the underlying B12 deficiency remains untreated. This is a critical safety concern.
Yes, Folate can interact with certain medications. These include some anti-seizure drugs, methotrexate (used for cancer and autoimmune diseases), and drugs that reduce stomach acid, which may affect Folate absorption or effectiveness. It is advisable to consult a healthcare professional about potential interactions.
Folate is considered safe and is crucially important during pregnancy for fetal development, particularly to prevent neural tube defects. Supplementation with synthetic folic acid is widely recommended before and during early pregnancy. It is also safe and beneficial during breastfeeding.
While Folate is water-soluble, exceptionally high intakes, particularly from synthetic folic acid, may lead to certain side effects. These can include abdominal cramps, diarrhea, or sleep problems. The tolerable upper intake level is established for synthetic folic acid.
Folate supplements are generally well-tolerated at recommended doses. Mild, rare side effects might include nausea, bloating, or sleep disturbances. Consuming extremely high doses over time could potentially lead to other effects.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Folate | 800 mcg |
Categories
Folate 85.0
This product utilizes Calcium Folinate, which is a superior and more readily usable form of folate compared to synthetic folic acid. Being in a reduced state, it bypasses initial metabolic steps, improving bioavailability and utilization for various crucial bodily functions.
Goals
General Health 85.0
Folinic acid is a well-utilized form of folate that efficiently supports fundamental cellular processes, including DNA synthesis and red blood cell production. This provides robust support for overall health and vitality, offering an upgrade from basic folic acid.
Heart Health 85.0
Folinic acid effectively aids in the metabolism of homocysteine, a key factor in cardiovascular health. Its superior absorption compared to folic acid ensures that the body can efficiently reduce homocysteine levels, thereby contributing to enhanced heart health.
Brain Health 80.0
By offering a more readily usable form of folate, this product supports the necessary biochemical pathways for neurotransmitter synthesis and overall neurological function more effectively than synthetic folic acid, contributing positively to cognitive well-being.
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