Total Cleanse Liver
Solaray
Total Cleanse Liver
4.8
★ ★ ★ ★ ★
(2236 ratings)
Gluthathione 25 mg
Selenium 100 mcg
Score 68.0
Solaray Total Cleanse Liver provides beneficial antioxidants like NAC, Selenium, and Vitamin C, which contribute to general health and detoxification. However, the key 'Liver Blend' is proprietary, obscuring crucial ingredient dosages, which hinders a full assessment of its targeted liver support capabilities.
Quantity: 60 Capsule(s)Servings size: 2 VegCap(s) (30 servings)
Selected goals:
Other goals:
Immunity
Detoxification
Skin Health
Brain Health
Anti-Aging
leaderboard Score 68.0
Solaray Total Cleanse Liver provides beneficial antioxidants like NAC, Selenium, and Vitamin C, which contribute to general health and detoxification. However, the key 'Liver Blend' is proprietary, obscuring crucial ingredient dosages, which hinders a full assessment of its targeted liver support capabilities.
insights Analysis
Solaray Total Cleanse Liver aims to support various aspects of health including immunity, anti-aging, skin health, metabolism, and detoxification, primarily through its blend of L-Glutathione, N-Acetyl Cysteine (NAC), Selenium (Selenomethionine), Vitamin C, and a proprietary 'Total Cleanse Liver Blend.' While NAC, Vitamin C, and Selenium are well-known for their antioxidant and supportive roles in detoxification and immune function, the 25mg of L-Glutathione is a very low dose, and its oral bioavailability is often debated. The main concern lies with the 635mg 'Total Cleanse Liver Blend' which hides the specific quantities of its ingredients. This lack of transparency means consumers cannot verify if the herbal components (e.g., milk thistle, dandelion, artichoke extract, often found in liver support formulas) are present in clinically effective doses. Online reviews often praise the Solaray brand generally, but for this specific product, the effectiveness for 'liver cleanse' is hard to quantify without knowing the blend's constituents. Competitors like LifeSeasons Puri-T offer clearer ingredient breakdowns for similar goals, providing a more reliable assessment of their liver-supporting components. The price per serving of $0.69 is reasonable for a multi-ingredient supplement, but the lack of transparency in the core blend reduces its overall value proposition for its primary stated goal.
- Contains N-Acetyl Cysteine (NAC), a potent precursor to glutathione, and strong antioxidants like Selenium and Vitamin C, which are beneficial for overall health and detoxification processes.
- Selenium is provided in the well-absorbed Selenomethionine form, contributing effectively to antioxidant defense and immune function.
- The primary 'Total Cleanse Liver Blend' is a proprietary blend, meaning individual ingredient quantities within it are not disclosed, making it impossible to ascertain if the liver-specific herbs are present in efficacious doses.
- The L-Glutathione dose (25mg) is very low and likely offers minimal direct benefit due to poor oral absorption, despite the inclusion of NAC which supports endogenous glutathione.
- The lack of transparency in the proprietary blend means consumers cannot make informed decisions about the specific herbal components and their dosages, potentially leading to underdosing of key liver-supportive ingredients.
$23.19($0.77 per serving)
 Amazon | $ 0.00 | |
 iHerb | $ 23.19 | |
 Vitacost | $ 23.19 |
bolt Effectiveness for goals
The effectiveness of oral glutathione supplements in directly raising intracellular glutathione levels is a subject of ongoing research. Some studies suggest limited bioavailability and breakdown in the digestive tract, while others indicate certain forms or delivery methods may be more effective. Precursors like N-acetylcysteine (NAC) are often more effective at raising levels.
Yes, selenium deficiency can impair the effectiveness of glutathione, particularly in its role as a substrate for glutathione peroxidase (GPx). Without sufficient selenium, the activity of GPx, a major antioxidant enzyme that utilizes glutathione, is reduced. This can diminish the body's overall antioxidant capacity.
Glutathione is often called the "master antioxidant" due to its critical role in protecting cells from oxidative stress and free radicals. It is involved in detoxification processes, helping to neutralize harmful substances in the liver. Glutathione also supports immune system function.
Glutathione is a major antioxidant involved in the body's detoxification processes. It helps neutralize harmful compounds and facilitates their elimination from the body. This includes both internally produced toxins and environmental pollutants.
Selenium is a trace mineral that plays a crucial role in thyroid hormone metabolism. It is a component of selenoproteins, which help protect the thyroid gland from oxidative damage and regulate hormone synthesis. Research suggests an association between adequate selenium intake and thyroid function.
schedule Dosage, timing & forms
The recommended daily allowance (RDA) for selenium for most adults is 55 micrograms (mcg). Some supplements may contain higher amounts, often used for specific purposes under professional guidance.
The Recommended Dietary Allowance (RDA) for adult men and women is 55 micrograms (mcg) per day. Supplement dosages often fall within a similar range or slightly higher, but generally below the Tolerable Upper Intake Level (UL) of 400 mcg per day.
The tolerable upper intake level (UL) for selenium for adults is 400 mcg per day. Consistently exceeding this limit can lead to adverse effects.
Common forms of selenium in supplements include selenomethionine and sodium selenite. Selenomethionine is an organic form often found in foods and is generally well-absorbed.
Yes, common forms include selenomethionine, which is often considered well-absorbed, and sodium selenite. The body may process these different forms distinctly.
health_and_safety Safety & interactions
Yes, excessive selenium intake can lead to a condition called selenosis. Symptoms include hair loss, nail discoloration or brittleness, nausea, diarrhea, and nervous system abnormalities. Long-term high intake can also be associated with serious health issues.
Yes, selenium and glutathione are often considered synergistic and can generally be taken together safely. Selenium is a cofactor for glutathione peroxidase, an enzyme that uses glutathione, indicating a complementary relationship in the body's antioxidant defense. Always adhere to recommended dosages for each supplement.
At recommended doses, selenium supplementation is generally well-tolerated. High doses, however, can lead to selenosis, characterized by hair loss, nail brittleness, and gastrointestinal upset. Other potential effects include skin rash or garlic breath.
There are no widely reported adverse interactions when combining selenium and glutathione supplements. In fact, selenium is essential for the function of glutathione peroxidase, an enzyme that utilizes glutathione to combat oxidative stress. This suggests a beneficial interaction between the two.
Selenium may interact with certain medications, such as some chemotherapy drugs, blood-thinning medications, and statins. It is advisable to consult a healthcare professional before combining selenium with prescribed medications to avoid potential interactions. Always disclose all supplements you are taking to your doctor.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin C | 120 mg |
Selenium | 100 mcg |
Total Cleanse Liver Blend | 635 mg |
N-Acetyl Cysteine | 200 mg |
L-Glutathione | 25 mg |
Categories
Selenium 72.0
The product provides 100mcg of Selenium in the well-absorbed Selenomethionine form, which is a good daily dose for antioxidant support. However, some alternative products offer higher concentrations (e.g., 200-300mcg) for more intensive supplementation.
Gluthathione 70.0
While the direct L-Glutathione dose (25mg) is quite low and potentially ineffective orally, the inclusion of 200mg of N-Acetyl Cysteine (NAC) is excellent, as NAC is a highly effective precursor that stimulates the body's natural production of glutathione, providing significant indirect glutathione support.
Goals
Immunity 75.0
The inclusion of Vitamin C and Selenium, both well-known for their immune-boosting properties, along with NAC which supports glutathione essential for immune cell function, provides good foundational support for immunity.
General Health 70.0
With a combination of essential antioxidants like Selenium and Vitamin C, plus the glutathione-supporting NAC, the product offers a good basis for overall cellular health and protection against oxidative stress.
Anti-Aging 68.0
The antioxidant powerhouse ingredients (NAC, Selenium, Vitamin C) combat oxidative stress, a major contributor to cellular aging, providing a supportive role in anti-aging efforts, though direct anti-aging claims are broad.
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