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Type l ll & lll Collagen Keratin with Alpha Lipoic Acid & Hyaluronic Acid

Solaray
4.7
★ ★ ★ ★ ★
(516 ratings)
Keratin 500 mg
Hyaluronic Acid 45 mg
Collagen 250 mg
Product Image
Score74
Well-dosed solubilized keratin makes sense for hair and nails, while the collagen and hyaluronic acid portions are small for the cost.
How scoring works
Quantity:60 Capsule(s) • (30 servings)
Goals:
Nail Health
Hair Health

Score 74

Well-dosed solubilized keratin makes sense for hair and nails, while the collagen and hyaluronic acid portions are small for the cost.
How scoring works
$35.88($1.19 per serving)
iHerb
$ 42.39
Vitacost
$ 42.39
Amazon
$ 35.88
Walmart
$ 35.88
Pure Formulas
$ 42.39
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Analysis

Solubilized keratin at 500 mg is the standout active and directly supplies a structural protein relevant to hair and nails. Vitamin C, zinc, and copper provide useful cofactors, while alpha-lipoic acid adds modest antioxidant support.

Marine type I and III collagen plus chicken type II collagen provide unusually clear source and type detail. Their combined 500 mg amount is still well below common collagen servings, and the 45 mg hyaluronic acid amount is also modest.

Two capsules concentrate several ingredients into a manageable routine, but the high ongoing cost weakens value. It best fits buyers focused on keratin who view collagen and hyaluronic acid as secondary additions.

Who is it for
  • Adults focused on hair and nail structure
  • People seeking oral solubilized keratin
  • Users who tolerate fish and chicken ingredients
Best for
  • Keratin-centered hair support
  • Nail structural support
  • Multi-ingredient beauty routines

Pros

  • Full targeted amount of solubilized keratin
  • Clear collagen sources and types
  • Includes vitamin C, zinc, and copper

Cons

  • Collagen amount is below gram-level use
  • Hyaluronic acid amount is low
  • High ongoing cost

Warnings

  • Fish and chicken collagen are unsuitable with corresponding food allergies.
  • Alpha-lipoic acid may lower blood glucose and add to diabetes-medicine effects.
  • Vitamin C and alpha-lipoic acid may cause digestive upset in sensitive users.

Nutrient quality

81 Highest impact

Solubilized keratin and chelated minerals are useful forms, but the collagen is not identified as hydrolyzed. Keratin is meaningfully dosed while collagen and hyaluronic acid are comparatively weak.

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Ingredient transparency

77 High impact

Active doses and collagen sources are clearly listed without a proprietary blend. Missing use directions and inactive ingredients prevent complete label transparency.

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Customer satisfaction

71 High impact

The average rating is very strong and supported by ample review volume. Detailed comments are unavailable, so common drawbacks and hair or nail experiences cannot be assessed.

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Value for money

65 Moderate impact

The targeted keratin dose supports some premium value, but the collagen and hyaluronic acid portions are modest. The relatively high serving cost makes the formula less competitive.

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Report analysis

Goals

Nail Health
Nail Health
Impact
Highest effect
A Goal FitA Strength of SupportA CoverageA Formula Quality
Collagen · 250 mgKeratin · 500 mg

A full solubilized keratin dose gives strong direct support for the protein that forms the nail plate. Vitamin C, zinc, and clearly sourced collagen add complementary support, although the collagen amount is small and not identified as hydrolyzed.

The formula covers structural protein, collagen synthesis, and mineral cofactors with clear active amounts. Fish and chicken collagen sources make it unsuitable for people with allergies to those ingredients.

Study evidence
Collagen Supportive 4 studies
Keratin Adverse 7 studies
Vitamin C Supportive 1 study
Zinc No effect 1 study
Hair Health
Hair Health
Impact
Highest effect
A Goal FitA- Strength of SupportA- CoverageA Formula Quality
Zinc · 3 mgVitamin C · 255 mgKeratin · 500 mgCollagen · 250 mg

Solubilized keratin directly supplies hair structural protein, while marine and chicken collagen contribute amino acids and scalp support. Vitamin C, zinc, copper, hyaluronic acid, and alpha-lipoic acid add synthesis, hydration, and antioxidant functions.

The keratin amount is substantial, but the combined collagen contribution remains below the gram-level amounts common in collagen research. Fish- or chicken-allergic users should avoid the corresponding collagen sources because they may trigger an allergic reaction.

Study evidence
Collagen Supportive 3 studies
Copper Adverse 4 studies
Hyaluronic Acid Mixed 7 studies
Keratin Disputed 14 studies
Vitamin C Mixed 5 studies
Zinc Supportive 22 studies

Ingredients

IngredientAmount per serving
Vitamin C (Ascorbic Acid)
 255 mg
Zinc (Zinc Amino Acid Chelate)
 3 mg
Copper (Copper Gluconate)
 280 mcg
Marine Collagen (Fish Collagen, Type I & III Collagen)
 250 mg
Chicken Collagen Type II
250 mg
Alpha Lipoic Acid
50 mg
Hyaluronic Acid
45 mg
Keratin, Solubilized
500 mg
Adults 18–50
Report overview
Keratin · 500 mg OverallScore84
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value

Solubilized keratin provides an absorption-ready form and a full targeted daily dose. Clear standalone disclosure makes the active amount easy to verify. The serving cost is high, so its strong formulation comes with only moderate value.

View ingredientView products
Hyaluronic Acid · 45 mg OverallScore36
F Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyF Value

Hyaluronic acid is listed without a salt form or molecular-weight detail, limiting confidence in oral absorption. The amount is low for meaningful systemic support. The source is undisclosed despite clear amount labeling. The cost and low active amount create poor value.

View ingredientView products
Collagen (Fish Collagen, Type I & III Collagen) · 250 mg OverallScore12
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

Fish type I and III collagen plus chicken type II collagen gives unusually clear source and type disclosure. The label does not say these collagens are hydrolyzed or use a clinically standardized brand. The combined amount remains below the lowest dose tier, protein and amino acid data are absent, and cost efficiency is poor.

View ingredientView products
Loading alternative details
81 Performance

Hair Skin & Nails Collagen Plus Formula

Life Extension
<p>Five hundred milligrams of Cynatine HNS keratin and 2,500 mg Verisol collagen provide stronger core ingredient coverage, supported by biotin, zinc, copper, and silicon. It lacks hyaluronic acid but appears more focused on hair and nail goals.</p>
70 Performance

Hair Skin & Nails

Bluebonnet Beautiful Ally
<p>One gram of types I and III collagen, soluble keratin, biotin, vitamin C, zinc, and MSM give broader hair and nail support. The keratin amount is only 50 mg and hyaluronic acid is absent, so it trades depth in those ingredients for breadth.</p>
70 Performance

Hair Skin and Nails

Dr. Mercola
<p>The 500 mg keratin amount matches the original and is paired with biotin and sodium hyaluronate in a shorter formula. Collagen, vitamin C, zinc, and copper are absent, so it is mainly preferable for users seeking a focused keratin option.</p>
81 Budget

Hair Skin & Nails Collagen Plus Formula

Life Extension
<p>The same 500 mg keratin amount is paired with 2,500 mg Verisol collagen, biotin, zinc, copper, and silicon at a much lower serving cost. Hyaluronic acid is absent, but the formula provides stronger collagen and keratin coverage.</p>
70 Budget

Hair Skin & Nails

Bluebonnet Beautiful Ally
<p>Types I and III collagen total 1,000 mg and are paired with soluble keratin, biotin, vitamin C, zinc, and MSM at a lower serving cost. Its keratin amount is smaller and it omits hyaluronic acid, creating a broader but less keratin-focused blend.</p>
70 Budget

Hair Skin and Nails

Dr. Mercola
<p>Keratin remains at 500 mg while biotin and 20 mg sodium hyaluronate provide a compact hair, skin, and nail formula at a slightly lower serving cost. It removes collagen and mineral cofactors, so the formula is simpler but less comprehensive.</p>
81 Value

Hair Skin & Nails Collagen Plus Formula

Life Extension
<p>Higher collagen, matching keratin, biotin, and mineral cofactors deliver stronger hair and nail coverage at less than half the serving cost. The main trade-off is the absence of hyaluronic acid.</p>
80 Value

Aquatic Beauty

NOW Solutions
<p>Two grams of fish collagen, 120 mg sodium hyaluronate, vitamin C, and astaxanthin provide substantially more collagen and hydration support for a lower serving cost. Keratin is absent, so it is better aligned with skin and joint goals than with hair structure.</p>
70 Value

Hair Skin & Nails

Bluebonnet Beautiful Ally
<p>One gram of collagen with biotin, vitamin C, zinc, keratin, and MSM offers broad hair and nail coverage at a lower serving cost. Smaller keratin and no hyaluronic acid are meaningful compromises.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The Effects of an Oral Supplementation of a Natural Keratin Hydrolysate on Skin Aging: A Randomized, Double-Blind, Placebo-Controlled Clinical Study in Healthy Women.
    Tursi F; Nobile V; Cestone E; De Ponti I; Lepoudere A; Sergheraert R; Soulard JP · Journal of cosmetic dermatology · 2025
    Randomized trialHair Health Nail Health forKeratin
  2. Comparative Analysis of Type I Keratin Expression By Nail Consistency: An Immunohistochemistry Study.
    Mingorance Álvarez E; Rodríguez-León J; Pérez Pico AM; Mayordomo R · Applied immunohistochemistry & molecular morphology : AIMM · 2022
    Cross-sectional study32 participantsNail Health forKeratin
  3. Low-Molecular-Weight Collagen Peptide Supplementation Improves Cellulite Severity, Skin Elasticity, and Hair Shaft Diameter: A Clinical Study with Pharmacokinetic Evaluation.
    Hwang S; Won J; Kim S; Kang W; Park M · Journal of medicinal food · 2026
    Randomized trial114 participantsHair Health forCollagen
  4. Calcium and Vitamin D Supplementation with and Without Collagen on Bone Density and Skin Elasticity in Menopausal Women-A Randomized Controlled Study.
    Duangjai A; Srivilai J; Nangola S; Amornlerdpison D · Clinics and practice · 2025
    Randomized trialHair Health forCollagen
  5. Dietary Collagen Supplementation as a Strategy for Skin Health: A Narrative Review of Clinical Effects on Skin, Hair, Nails, and Wound Healing.
    Biełach-Bazyluk A; Jurga M; Flisiak I; Zbroch E · Nutrients · 2026
    Narrative reviewHair Health forCollagen
  6. Menkes disease and response to copper histidine: An Indian case series.
    Yoganathan S; Sudhakar SV; Arunachal G; Thomas M; Subramanian A; George R; Danda S · Annals of Indian Academy of Neurology · 2022
    Case series4 participantsHair Health forCopper
  7. Trace element levels in alopecia areata.
    Bhat YJ; Manzoor S; Khan AR; Qayoom S · Indian journal of dermatology, venereology and leprology · 2009
    Case-control study100 participantsHair Health forCopper
  8. UV damage to hair and the effect of antioxidants and metal chelators.
    Millington KR; Marsh JM · International journal of cosmetic science · 2021
    In vitro / ex vivo studyHair Health forCopper
  9. Preserving fibre health: reducing oxidative stress throughout the life of the hair fibre.
    Marsh JM; Davis MG; Lucas RL; Reilman R; Styczynski PB; Li C; Mamak M; McComb DW; Williams RE; Godfrey S; Navqi KR; Chechik V · International journal of cosmetic science · 2016
    In vitro / ex vivo studyHair Health forCopper
  10. Efficacy and safety of non-cross-linked hyaluronic acid compound in the treatment of keratosis pilaris: A split-body randomized clinical trial.
    Li Y; Wang SW; Liu YH; Zou MY; Wu JX; Luo SK; Hong WJ · Journal of cosmetic dermatology · 2024
    Randomized trialHair Health forHyaluronic Acid
  11. Intradermal Injections of 10% Glucose (Sihler G) for Scalp Hair Regrowth: A Randomized, Evaluator-Blinded Pilot Study.
    Yi KH; Sydorchuk O; Lee S; Sobchyshyn M; Kim TH; Lee SR; Park S; Chang-Il Y; Kyu-Eun L · Aesthetic plastic surgery · 2026
    Observational studyHair Health forHyaluronic Acid
  12. Efficacy of Dr. SKS Hair Booster Serum in the Treatment of Female Pattern Alopecia in Patients With PCOS: An Open-Label, Non-randomized, Prospective Study.
    Khare S · Cureus · 2023
    Randomized trialHair Health forHyaluronic Acid
  13. Efficacy and safety of needle-free jet injector-assisted intralesional treatments in dermatology-a systematic review.
    Bekkers VZ; Bik L; van Huijstee JC; Wolkerstorfer A; Prens EP; van Doorn MBA · Drug delivery and translational research · 2023
    Systematic reviewHair Health forHyaluronic Acid
  14. Revitalizing Effect on the Scalp After Injection with a Mechanically Stabilized Hyaluronic Acid Complex in Subjects with Androgenetic Alopecia.
    Siquier-Dameto G; Boisnic S; Verdú E · Journal of clinical medicine · 2024
    Clinical trial26 participantsHair Health forHyaluronic Acid
  15. Halloysite/Keratin Nanocomposite for Human Hair Photoprotection Coating.
    Cavallaro G; Milioto S; Konnova S; Fakhrullina G; Akhatova F; Lazzara G; Fakhrullin R; Lvov Y · ACS applied materials & interfaces · 2021
    In vitro / ex vivo studyHair Health forKeratin
  16. Annurca Apple Nutraceutical Formulation Enhances Keratin Expression in a Human Model of Skin and Promotes Hair Growth and Tropism in a Randomized Clinical Trial.
    Tenore GC; Caruso D; Buonomo G; D'Avino M; Santamaria R; Irace C; Piccolo M; Maisto M; Novellino E · Journal of medicinal food · 2018
    Randomized trialHair Health forKeratin
  17. Keratin/alginate hybrid hydrogels filled with halloysite clay nanotubes for protective treatment of human hair.
    Cavallaro G; Caruso MR; Milioto S; Fakhrullin R; Lazzara G · International journal of biological macromolecules · 2022
    In vitro / ex vivo studyHair Health forKeratin
  18. Patient Satisfaction and Adverse Effects Following the use of Topical Hair Fiber Fillers.
    Babadjouni A; Juhasz M; Pham C; Csuka E; Hedayati B; Evron E; Mesinkovska NA · International journal of trichology · 2024
    Cross-sectional study40 participantsHair Health forKeratin
  19. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  20. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
    Methods validation study201,019 participantsHair Health forVitamin C
  21. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  22. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
    Methods validation studyHair Health forVitamin C
  23. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
    Case reportHair Health forVitamin C
  24. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  25. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  26. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  27. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  28. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  29. Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails.
    Hexsel D; Zague V; Schunck M; Siega C; Camozzato FO; Oesser S · Journal of cosmetic dermatology · 2018
    Single-arm trial25 participantsNail Health forCollagen
  30. Influence of collagen peptide supplementation on visible signs of skin and nail health and -aging in an East Asian population: A double blind, randomized, placebo-controlled trial.
    Vleminckx S; Virgilio N; Asserin J; Prawitt J; Silva CIF · Journal of cosmetic dermatology · 2024
    Randomized trial85 participantsNail Health forCollagen
  31. Nail Supplements: When, How, and Why?
    Zaraa I; Richert B · Skin appendage disorders · 2026
    Narrative reviewNail Health forCollagen
  32. Expanding the COL7A1 mutation database: novel and recurrent mutations and unusual genotype-phenotype constellations in 41 patients with dystrophic epidermolysis bullosa.
    Kern JS; Kohlhase J; Bruckner-Tuderman L; Has C · The Journal of investigative dermatology · 2006
    Observational study41 participantsNail Health forCollagen
  33. Exposure to toxic agents alters organic elemental composition in human fingernails.
    Schumacher E; Dindorf W; Dittmar M · The Science of the total environment · 2009
    Cross-sectional study120 participantsNail Health forKeratin
  34. Human keratin diseases: hereditary fragility of specific epithelial tissues.
    Corden LD; McLean WH · Experimental dermatology · 1997
    Narrative reviewNail Health forKeratin
  35. Phenotype and genotype features of Vietnamese children with pachyonychia congenita.
    Chu HT; Dinh Duong TA; Le DH; Le TV; Nguyen BB; Dang CV; Vu QV · Pediatrics and neonatology · 2023
    Case series7 participantsNail Health forKeratin
  36. Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient.
    Dunleavy KA; Ungaro RC; Manning L; Gold S; Novak J; Colombel JF · Crohn's & colitis 360 · 2023
    Other20 participantsNail Health forVitamin C
  37. Vitamins and minerals: their role in nail health and disease.
    Scheinfeld N; Dahdah MJ; Scher R · Journal of drugs in dermatology : JDD · 2007
    Narrative reviewNail Health forZinc