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Neuro-Peak

ZHOU
4.3
★ ★ ★ ★ ★
(3005 ratings)
Vitamin B12 500 mcg
Deanol 50 mg
Ginkgo
Rhodiola
Bacopa 200 mg
Product Image
Score73
A focused once-daily nootropic blend with useful ginkgo and bacopa amounts, held back by weak standardization and unclear huperzine A yield.
How scoring works
Quantity:30 Capsule(s) • (30 servings)
Goals:
Cognitive Support
Productivity Boost
Brain Health
Energy
Mental Focus

Score 73

A focused once-daily nootropic blend with useful ginkgo and bacopa amounts, held back by weak standardization and unclear huperzine A yield.
How scoring works
$23.19($0.77 per serving)
Walmart
$ 23.19
iHerb
$ 23.19
Vitacost
$ 23.19
Report prices

Analysis

Ginkgo at 240 mg and bacopa at 200 mg provide the main cognitive foundation, with methylcobalamin, rhodiola, DMAE, and huperzia adding energy and cholinergic pathways. The once-daily capsule is convenient.

Ginkgo and bacopa active-marker percentages are not stated, while rhodiola and DMAE are modest. Most importantly, 0.5 mg Huperzia serrata does not reveal the actual huperzine A amount, making potency difficult to judge.

The blend may suit experienced users seeking broad cognitive support without caffeine. Unclear standardization and the cholinergic interaction profile make it less suitable for users who want predictable dosing.

Who is it for
  • Adults seeking a caffeine-free nootropic blend
  • Experienced users comfortable with multi-herb formulas
  • People prioritizing cognition and productivity over other listed goals
Best for
  • Cognitive support
  • Mental focus
  • Once-daily nootropic use

Pros

  • Provides 240 mg ginkgo extract
  • Includes 200 mg bacopa
  • Uses methylcobalamin
  • Convenient one-capsule serving

Cons

  • Ginkgo and bacopa lack marker standardization
  • Huperzine A yield is not disclosed
  • Rhodiola and DMAE are modest
  • Weak fit for hair and vision goals

Warnings

  • Huperzia may supply huperzine A and can interact with cholinergic or anticholinergic medicines
  • Ginkgo may add to bleeding risk with anticoagulant or antiplatelet medicines
  • Rhodiola may feel stimulating and can disrupt sleep or aggravate restlessness in sensitive users

Nutrient quality

70 High impact

Meaningful bacopa and ginkgo doses provide a focused cognitive base. Aggressive huperzine exposure and absent botanical standardization create important potency and safety uncertainty.

.

Ingredient transparency

74 High impact

The main active amounts are generally available and no broad proprietary blend obscures the formula. Complete usage directions and non-active ingredients are not supplied, while any noted duplicate or vague entries reduce clarity.

.

Customer satisfaction

69 High impact

Aggregate satisfaction is fairly strong and supported by an extensive evidence base. No firsthand experience details are supplied, so recurring complaints and purpose alignment remain uncertain.

.

Value for money

78 High impact

Meaningful core botanical doses and a concise formula support fair value. Huperzine and standardization uncertainty prevent a stronger quality conclusion.

.
Report analysis

Goals

Cognitive Support
Cognitive Support
Impact
High effect
B+ Goal FitC+ Strength of SupportB+ CoverageB- Formula Quality
Vitamin B12 · 500 mcgBacopa · 200 mg

Ginkgo, bacopa, huperzine-containing club moss, rhodiola, and DMAE address circulation, memory signaling, stress, and neurotransmitter pathways. Ginkgo is supplied in a substantial amount, while bacopa provides a credible memory-focused botanical.

Several extracts lack standardization details, and rhodiola plus DMAE appear modest relative to focused products. The formula has strong conceptual breadth but only moderate confidence in active yields and dose depth.

Study evidence
Bacopa Supportive 30 studies
Deanol No effect 2 studies
Ginkgo Supportive 87 studies
Rhodiola Supportive 7 studies
Productivity Boost
Productivity Boost
Impact
High effect
B+ Goal FitC Strength of SupportB CoverageA- Formula Quality
Vitamin B12 · 500 mcgVitamin B12 · 500 mcg

Ginkgo, bacopa, rhodiola, clubmoss, and methylcobalamin form a direct nootropic blend for memory, circulation, and fatigue resistance. Ginkgo reaches a strong amount and provides the clearest likely contribution.

Bacopa is modest, rhodiola is low, and none of the botanicals disclose defining marker percentages. Ginkgo may increase bleeding risk with anticoagulant or antiplatelet medicines, while clubmoss-derived huperzine may interact with cholinergic medicines.

Study evidence
Bacopa Supportive 12 studies
Ginkgo Supportive 20 studies
Ginkgo Supportive 12 studies
Rhodiola Supportive 7 studies
Vitamin B12 Supportive 15 studies
Vitamin B12 No effect 17 studies
Brain Health
Brain Health
Impact
High effect
B Goal FitD+ Strength of SupportB- CoverageB+ Formula Quality
Vitamin B12 · 500 mcgBacopa · 200 mg

Bacopa, ginkgo, rhodiola, club moss, DMAE, and methylcobalamin create a directly targeted cognitive blend. Ginkgo is substantial, but the lack of marker standardization and the very low rhodiola amount make actual potency uneven.

The compact formula covers memory, circulation, stress response, and cholinergic signaling without many unrelated extras. Ginkgo may interact with anticoagulant or antiplatelet medicines, while club moss compounds may matter with cholinergic or anticholinergic drugs.

Study evidence
Bacopa Supportive 17 studies
Ginkgo Supportive 90 studies
Rhodiola Supportive 8 studies
Vitamin B12 Supportive 74 studies
Energy
Energy
Impact
High effect
B- Goal FitC Strength of SupportC+ CoverageC+ Formula Quality
Vitamin B12 · 500 mcg

Methylcobalamin, rhodiola, and cognitive-support ingredients span metabolism, stress response, and focus. The combination has a plausible energy and concentration rationale but uneven evidence at the supplied amounts.

Rhodiola is below a typical clinical range and lacks active-marker standardization, while B12 is more convincingly dosed. Ginkgo and huperzine A may interact with anticoagulant or cholinergic medicines.

Study evidence
Rhodiola Supportive 18 studies
Vitamin B12 Disputed 14 studies
Mental Focus
Mental Focus
Impact
High effect
B- Goal FitC- Strength of SupportB- CoverageB- Formula Quality
Vitamin B12 · 500 mcg

Ginkgo, bacopa, huperzia, rhodiola, DMAE, and methylcobalamin give the formula clear cognitive relevance. Ginkgo is substantial, but bacopa and rhodiola are modest and the extracts lack the standardization needed for reliable potency.

The single-capsule serving covers circulation, memory signaling, stress response, and nutritional support without excessive unrelated ingredients. Ginkgo may increase bleeding risk with anticoagulant or antiplatelet medicines, while huperzia-derived cholinergic activity may interact with cholinergic or anticholinergic drugs.

Study evidence
Bacopa Supportive 13 studies
Ginkgo Supportive 28 studies
Rhodiola Supportive 15 studies
Vitamin B12 Disputed 11 studies
General Health
General Health
Impact
Moderate effect
C- Goal FitC- Strength of SupportD CoverageB Formula Quality
Vitamin B12 · 500 mcg

Methylcobalamin and several cognitive botanicals offer targeted neurological and stress-related support. The product is better viewed as a specialty nootropic than a broad general-health supplement.

Rhodiola is low and unstandardized, while bacopa and ginkgo also lack standardization details. Ginkgo and huperzine-related activity may interact with anticoagulant or cholinergic medicines.

Study evidence
Rhodiola Supportive 7 studies
Vitamin B12 Adverse 66 studies

Ingredients

IngredientAmount per serving
Vitamin B12 (Methylcobalamin)
 500 mcg
Bacopa monnieri leaf extract
200 mg
Huperzine Serrata
0.5 mg
Ginkgo biloba leaf extract
240 mg
Rhodiola rosea root extract
50 mg
DMAE (Dimethylaminoethanol Bitartrate)
 50 mg
Gluten Free Adults 18–50 Women
Report overview
Vitamin B12 (Methylcobalamin) · 500 mcg OverallScore71
A- Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

Methylcobalamin provides a bioactive B12 form, but the standard capsule offers no specialized absorption route. The 500 mcg amount supports moderate needs rather than the highest therapeutic band. Ginkgo and huperzine A also warrant caution for people using anticoagulants or cholinergic medicines because their effects may interact.

View ingredientView products
Ginkgo · 240 mg OverallScore48
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The leaf extract amount sits at the upper end of the effective range, but the label does not verify standardization. The exact standalone amount is clear, but no qualifying ginkgolic acid purity assurance is supplied. Ginkgo may increase bleeding risk with anticoagulant or antiplatelet medicines.

View ingredientView products
Deanol (Dimethylaminoethanol Bitartrate) · 50 mg OverallScore48
B- Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyF Value

DMAE bitartrate is clearly identified, but the label does not state how much active Deanol it yields. The listed salt amount supplies about 18.5 mg active Deanol, leaving the dose quite low for focused supplementation. One capsule is easy to take, though the Deanol delivered is poor value relative to the product cost.

View ingredientView products
Loading alternative details
76 Performance

Nu Clarity

CogniTune Smarter Health
Bacopa, alpha-GPC, phosphatidylserine, ginkgo, rhodiola, and huperzine A create a broader and more balanced cognitive blend than the original. Repeated standardization entries cloud exact extract amounts, and huperzine A may be unsuitable with cholinergic medicines.
75 Performance

Brain Cell Support

Metabolic Maintenance
Acetyl-L-carnitine, citicoline, phosphatidylserine, standardized ginkgo, and gotu kola provide stronger membrane and energy support than the original’s narrower blend. The serving cost is higher, and duplicated extract entries introduce some uncertainty.
75 Performance

Memoractiv

Thorne
Branded ashwagandha and ginkgo forms combine with acetyl-L-carnitine, carotenoids, and caffeine for well-specified cognitive and stress support. The serving cost is high and several supporting doses are modest, but ingredient form quality is stronger.
76 Budget

Pure Brainpower

Swanson
The lower-cost serving provides a strong bacopa amount with complementary ginkgo and coffee-fruit extract, while avoiding the original’s aggressive stated huperzine amount. Active-marker disclosure remains incomplete, but the formula is focused and practical.
78 Budget

Ginkgo+

NS Natural Stacks
The lower-cost serving pairs well-sized ginseng, bacopa, and ginkgo in a coherent cognitive blend. Missing marker percentages and ginkgo purity details remain the main limitations, but the ingredient set is simpler than the original.
77 Budget

Memory Complex

Natrol
The lower-cost serving combines substantial bacopa and ginkgo with a much smaller stated huperzine amount and supporting B vitamins. Marker percentages are incomplete and phosphatidylserine is only a token addition, while ginkgo may interact with blood-thinning medicines.
72 Value

NeuroIGNITE

Havasu Nutrition
A slightly lower-cost serving centers on a substantial bacopa amount and keeps ginkgo, DMAE, and acetyl-L-carnitine in the blend. St. John’s wort creates extensive medicine-interaction concerns, which sharply narrows who can use it safely.
57 Value

ThinkFast

Futurebiotics
A lower-cost serving provides recognized bacopa and substantial ginkgo amounts in a compact cognitive core. Hidden blends and incomplete extract standards weaken transparency, so the value advantage depends on accepting less disclosure.
57 Value

Think Support

Zoi Research
The lower-cost serving keeps bacopa and ginkgo as the main cognitive ingredients and offers a longer supply. Proprietary blends conceal supporting doses and active-marker percentages, making quality harder to judge than with the original.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Ginkgo biloba for cognitive impairment and dementia.
    Wieland LS; Ludeman E; Chi Y; Feinberg TM; Chen IH; Chen KH; Zhu Y; Wolverson E; Amri H · The Cochrane database of systematic reviews · 2026
    Meta-analysis10,613 participants82 studies pooledCognitive Support forGinkgo
  2. Comparative effects of Bacopa monnieri and Ginkgo biloba on cognitive functions: A systematic review and network meta-analysis.
    Tiemtad P; Ingkaninan K; Temkitthawon P; Thimkorn P; Rattanachaisit N; Teaktong T; Dhippayom T · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2026
    Meta-analysis2,107 participants29 studies pooledCognitive Support Brain Health Mental Focus forBacopa
  3. Rhodiola rosea for mental and physical fatigue in nursing students: a randomized controlled trial.
    Punja S; Shamseer L; Olson K; Vohra S · PloS one · 2015
    Randomized trial48 participantsEnergy forRhodiola
  4. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  5. Ginkgo biloba Extract (EGb761), Cholinesterase Inhibitors, and Memantine for the Treatment of Mild-to-Moderate Alzheimer's Disease: A Network Meta-Analysis.
    Thancharoen O; Limwattananon C; Waleekhachonloet O; Rattanachotphanit T; Limwattananon P; Limpawattana P · Drugs & aging · 2019
    Meta-analysisCognitive Support forGinkgo
  6. Scientific Opinion on the substantiation of a health claim related to Rhodiola rosea L. extract and reduction of mental fatigue pursuant to Article 13(5) of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forRhodiola
  7. Association of Vitamin B12, Vitamin D, and Thyroid-Stimulating Hormone With Fatigue and Neurologic Symptoms in Patients With Fibromyalgia.
    Munipalli B; Strothers S; Rivera F; Malavet P; Mitri G; Abu Dabrh AM; Dawson NL · Mayo Clinic proceedings. Innovations, quality & outcomes · 2022
    Observational study2,142 participantsEnergy forVitamin B12
  8. The acute effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy normal subjects.
    Nathan PJ; Clarke J; Lloyd J; Hutchison CW; Downey L; Stough C · Human psychopharmacology · 2019
    Randomized trial38 participantsCognitive Support forBacopa
  9. Rhodiola rosea for physical and mental fatigue: a systematic review.
    Ishaque S; Shamseer L; Bukutu C; Vohra S · BMC complementary and alternative medicine · 2013
    Systematic review11 studies pooledEnergy forRhodiola
  10. Association between serum vitamin B12 level and frailty in older adults.
    Dokuzlar O; Soysal P; Isik AT · Northern clinics of Istanbul · 2022
    Cross-sectional study335 participantsEnergy forVitamin B12
  11. Efficacy of Ginkgo biloba extract EGb 761® in dementia with behavioural and psychological symptoms: A systematic review.
    von Gunten A; Schlaefke S; Überla K · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2017
    Meta-analysis1,628 participants4 studies pooledCognitive Support Brain Health forGinkgo
  12. The cognitive-enhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials.
    Pase MP; Kean J; Sarris J; Neale C; Scholey AB; Stough C · Journal of alternative and complementary medicine (New York, N.Y.) · 2012
    Systematic review6 studies pooledCognitive Support Productivity Boost forBacopa
  13. Efficacy of ginkgo diterpene lactone meglumine on cognitive function in patients with acute ischemic stroke: a predefined exploratory analysis of a multicenter, double-blind, randomized controlled trial.
    Tian X; Xu Q; Xia X; Zhang Y; Meng X; Wang A · Journal of neurology · 2024
    Randomized trial3,163 participantsCognitive Support forGinkgo
  14. Chronic effects of Brahmi (Bacopa monnieri) on human memory.
    Roodenrys S; Booth D; Bulzomi S; Phipps A; Micallef C; Smoker J · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2002
    Randomized trial76 participantsCognitive Support forBacopa
  15. The Effect of Short-Term Rhodiola rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players.
    Wang J; Zhao H; Yu L; Zhao K; Jiang W; Liu S; Dai J; Xu L; Sun P; Yun H; Liu C · Nutrients · 2025
    Randomized trial48 participantsEnergy forRhodiola
  16. A cross-sectional study of nutritional status in healthy, young, physically-active German omnivores, vegetarians and vegans reveals adequate vitamin B12 status in supplemented vegans.
    Storz MA; Müller A; Niederreiter L; Zimmermann-Klemd AM; Suarez-Alvarez M; Kowarschik S; Strittmatter M; Schlachter E; Pasluosta C; Huber R; Hannibal L · Annals of medicine · 2023
    Cross-sectional study115 participantsEnergy forVitamin B12
  17. Meta-analysis of the efficacy and safety of Ginkgo biloba extract for the treatment of dementia.
    Hashiguchi M; Ohta Y; Shimizu M; Maruyama J; Mochizuki M · Journal of pharmaceutical health care and sciences · 2016
    Meta-analysis2,381 participants13 studies pooledCognitive Support forGinkgo
  18. Comparative efficacy of Medhya Rasayana,Bacopa monnieri, and Centella asiatica in enhancing memory and IQ of 8-10 year-old healthy boys: A prakriti-based double-blind, randomized controlled trial.
    Verma J; Rathi R; Anamika; Rathi B; Pandey VB · Journal of Ayurveda and integrative medicine · 2025
    Randomized trial180 participantsCognitive Support Brain Health forBacopa
  19. Effects of Rhodiola rosea on Physical and Decision-Making Performance in Football Players: A Randomised Controlled Trial.
    Dou Y; Wang Y; Zhang W; Jiang Y; Zhang J; Yang T; Han Z; Li Y; Liu C; Ren D · Nutrients · 2026
    Randomized trial24 participantsEnergy Mental Focus forRhodiola
  20. Megaloblastic anaemia: prevalence and causative factors.
    Khanduri U; Sharma A · The National medical journal of India · 2008
    Observational study175 participantsEnergy forVitamin B12
  21. A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group.
    Le Bars PL; Katz MM; Berman N; Itil TM; Freedman AM; Schatzberg AF · JAMA · 1997
    Randomized trial309 participantsCognitive Support Productivity Boost forGinkgo
  22. A systematic review of the Ayurvedic medicinal herb Bacopa monnieri in child and adolescent populations.
    Kean JD; Downey LA; Stough C · Complementary therapies in medicine · 2017
    Systematic review5 studies pooledCognitive Support forBacopa
  23. The Effect of Acute Rhodiola rosea Ingestion on Exercise Heart Rate, Substrate Utilisation, Mood State, and Perceptions of Exertion, Arousal, and Pleasure/Displeasure in Active Men.
    Duncan MJ; Clarke ND · Journal of sports medicine (Hindawi Publishing Corporation) · 2015
    Clinical trial10 participantsEnergy forRhodiola
  24. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  25. Ginkgo biloba extract EGb 761 is safe and effective in the treatment of mild dementia - a meta-analysis of patient subgroups in randomised controlled trials.
    Riepe M; Hoerr R; Schlaefke S · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2025
    Meta-analysis782 participants4 studies pooledCognitive Support Brain Health Productivity Boost forGinkgo
  26. The effectiveness of Bacopa monnieri (Linn.) Wettst. as a nootropic, neuroprotective, or antidepressant supplement: analysis of the available clinical data.
    Brimson JM; Brimson S; Prasanth MI; Thitilertdecha P; Malar DS; Tencomnao T · Scientific reports · 2021
    Meta-analysisCognitive Support forBacopa
  27. Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial.
    Lekomtseva Y; Zhukova I; Wacker A · Complementary medicine research · 2019
    Single-arm trial100 participantsEnergy General Health forRhodiola
  28. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  29. Alleviating neuropsychiatric symptoms in dementia: the effects of Ginkgo biloba extract EGb 761. Findings from a randomized controlled trial.
    Bachinskaya N; Hoerr R; Ihl R · Neuropsychiatric disease and treatment · 2011
    Randomized trial410 participantsCognitive Support forGinkgo
  30. Effects of Bacopa monnieri (CDRI 08®) in a population of males exhibiting inattention and hyperactivity aged 6 to 14 years: A randomized, double-blind, placebo-controlled trial.
    Kean JD; Downey LA; Sarris J; Kaufman J; Zangara A; Stough C · Phytotherapy research : PTR · 2022
    Randomized trial112 participantsCognitive Support forBacopa
  31. Combined Rhodiola rosea and eccentric training boost endurance performance and lower-limb reactive strength in recreationally active women.
    Wang IL; Su Y; Zhang L; Tang M; Chen YM · Frontiers in physiology · 2025
    Randomized trial30 participantsEnergy forRhodiola
  32. Vitamin B12 Supplementation: Is More Always Better?
    Yepes-Calderón M; Doorenbos CSE; Stegmann ME; Touw DJ; Harmsen HJM; Heiner-Fokkema MR; van Spronsen FJ; Corpeleijn E; Bakker SJL · Nutrients · 2026
    Narrative reviewEnergy forVitamin B12
  33. EGb in the Treatment for Patients with VCI: A Systematic Review and Meta-Analysis.
    Zhan M; Sun L; Liu J; Zeng Z; Shen W; Li H; Wang Y; Han F; Shi J; Zeng X; Lu X; Zhang Y; Liao X · Oxidative medicine and cellular longevity · 2022
    Meta-analysis2,019 participants23 studies pooledCognitive Support forGinkgo
  34. The effect of plant active substances on cognitive function in healthy older adults: a systematic review and network meta-analysis of randomized controlled trials.
    Feng X; Fan S; Wei F · Frontiers in pharmacology · 2026
    Meta-analysis1,861 participants25 studies pooledCognitive Support Brain Health forBacopa
  35. The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue Conditions: A Randomized, Triple-Blinded, Placebo-Controlled, Crossover Trial.
    Marcos-Frutos D; Leban Ž; Li Z; Zhang X; Lara PM; Alix-Fages C; Jiménez-Martínez P; Zebboudji N; Caillet A; Redondo B; Vera J; Janicijevic D; García-Ramos A · Nutrients · 2025
    Randomized trial18 participantsEnergy forRhodiola
  36. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  37. Efficacy and adverse effects of ginkgo biloba for cognitive impairment and dementia: a systematic review and meta-analysis.
    Tan MS; Yu JT; Tan CC; Wang HF; Meng XF; Wang C; Jiang T; Zhu XC; Tan L · Journal of Alzheimer's disease : JAD · 2015
    Meta-analysis2,561 participants9 studies pooledCognitive Support Brain Health forGinkgo
  38. Randomized controlled trial of standardized Bacopa monniera extract in age-associated memory impairment.
    Raghav S; Singh H; Dalal PK; Srivastava JS; Asthana OP · Indian journal of psychiatry · 2011
    Randomized trialCognitive Support forBacopa
  39. Therapeutic effects and safety of Rhodiola rosea extract WS® 1375 in subjects with life-stress symptoms--results of an open-label study.
    Edwards D; Heufelder A; Zimmermann A · Phytotherapy research : PTR · 2012
    Single-arm trial101 participantsEnergy forRhodiola
  40. Trends in energy and nutrient intake and risk of inadequate intakes in Catalonia, Spain (1992-2003).
    Serra-Majem L; Ribas-Barba L; Salvador G; Jover L; Raidó B; Ngo J; Plasencia A · Public health nutrition · 2008
    Cross-sectional study4,701 participantsEnergy forVitamin B12
  41. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract.
    Kongkeaw C; Dilokthornsakul P; Thanarangsarit P; Limpeanchob N; Norman Scholfield C · Journal of ethnopharmacology · 2014
    Meta-analysis518 participants9 studies pooledBrain Health Mental Focus Productivity Boost forBacopa
  42. Plant-derived nootropics and human cognition: A systematic review.
    Lorca C; Mulet M; Arévalo-Caro C; Sanchez MÁ; Perez A; Perrino M; Bach-Faig A; Aguilar-Martínez A; Vilella E; Gallart-Palau X; Serra A · Critical reviews in food science and nutrition · 2023
    Systematic review256 studies pooledBrain Health forBacopa
  43. Ginkgo biloba extract EGb 761® improves cognition and overall condition after ischemic stroke: Results from a pilot randomized trial.
    Cui M; You T; Zhao Y; Liu R; Guan Y; Liu J; Liu X; Wang X; Dong Q · Frontiers in pharmacology · 2023
    Randomized trial201 participantsBrain Health Productivity Boost forGinkgo
  44. Ginkgo biloba extract EGb 761® in dementia with neuropsychiatric features: a randomised, placebo-controlled trial to confirm the efficacy and safety of a daily dose of 240 mg.
    Herrschaft H; Nacu A; Likhachev S; Sholomov I; Hoerr R; Schlaefke S · Journal of psychiatric research · 2012
    Randomized trial410 participantsBrain Health forGinkgo
  45. Dose-Response Effects of Short-Term Rhodiola rosea (Golden Root Extract) Supplementation on Anaerobic Exercise Performance and Cognitive Function in Resistance-Trained Athletes: A Randomized, Crossover, Double-Blind, and Placebo-Controlled Study.
    Koozehchian MS; Newton AT; Mabrey G; Bonness FM; Rafajlovska R; Naderi A · Nutrients · 2025
    Randomized trial27 participantsBrain Health Mental Focus forRhodiola
  46. A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers.
    Boyle NB; Billington J; Lawton C; Quadt F; Dye L · Nutritional neuroscience · 2022
    Randomized trial100 participantsBrain Health forRhodiola
  47. Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy.
    Panossian A; Wikman G; Sarris J · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2010
    Narrative reviewBrain Health forRhodiola
  48. Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.
    Darbinyan V; Kteyan A; Panossian A; Gabrielian E; Wikman G; Wagner H · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2001
    Randomized trial56 participantsBrain Health General Health Productivity Boost forRhodiola
  49. Effects of a Rhodiola rosea extract on mental resource allocation and attention: An event-related potential dual task study.
    Koop T; Dienel A; Heldmann M; Münte TF · Phytotherapy research : PTR · 2021
    Single-arm trial50 participantsBrain Health Cognitive Support forRhodiola
  50. Relationship between vitamin B12 levels and motor development: A systematic review.
    Dos Santos MERA; da Silva KG; da Silva Souza AP; da Silva ABJ; da Silva RF; da Silva EHA; de Souza SL; Barros WMA · Clinical nutrition ESPEN · 2024
    Systematic review1,559 participants8 studies pooledBrain Health forVitamin B12
  51. Vitamin B12 supplementation improves cognitive function in middle aged and elderly patients with cognitive impairment.
    Zhou L; Bai X; Huang J; Tan Y; Yang Q · Nutricion hospitalaria · 2023
    Randomized trial115 participantsBrain Health Mental Focus forVitamin B12
  52. Structural and Functional Brain Changes Associated with Vitamin B12 Deficiency using Magnetic Resonance Imaging: A Systematic Review and Meta-analysis.
    Alghamdi A · Current medical imaging · 2023
    Meta-analysis12 studies pooledBrain Health forVitamin B12
  53. Maternal vitamin B12, vitamin D, and folic acid status during pregnancy and child neurodevelopment: a systematic review.
    Franco L; de Andrade CVF; Margini LV; Sousa N · Frontiers in neuroscience · 2026
    Systematic review22 studies pooledBrain Health forVitamin B12
  54. Higher vitamin B12 from mid- to late life is related to slower rates of cognitive decline.
    Marino FR; Rogers G; Miller JW; Selhub J; Mez J; Crane PK; Mukherjee S; Saykin AJ; Hohman TJ; Trittschuh EH; Au R; Jacques PF; Hwang PH · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Cohort study1,994 participantsBrain Health forVitamin B12
  55. Efficacy of Standardized Extract of Bacopa monnieri (Bacognize®) on Cognitive Functions of Medical Students: A Six-Week, Randomized Placebo-Controlled Trial.
    Kumar N; Abichandani LG; Thawani V; Gharpure KJ; Naidu MU; Venkat Ramana G · Evidence-based complementary and alternative medicine : eCAM · 2024
    Randomized trial60 participantsCognitive Support forBacopa
  56. Senile dementia: treatment with deanol.
    Ferris SH; Sathananthan G; Gershon S; Clark C · Journal of the American Geriatrics Society · 1977
    Single-arm trial14 participantsCognitive Support forDeanol
  57. Effects of dimethylaminoethanol pyroglutamate (DMAE p-Glu) against memory deficits induced by scopolamine: evidence from preclinical and clinical studies.
    Blin O; Audebert C; Pitel S; Kaladjian A; Casse-Perrot C; Zaim M; Micallef J; Tisne-Versailles J; Sokoloff P; Chopin P; Marien M · Psychopharmacology · 2010
    Randomized trial24 participantsCognitive Support forDeanol
  58. Efficacy and safety of a once-daily formulation of Ginkgo biloba extract EGb 761 in dementia with neuropsychiatric features: a randomized controlled trial.
    Ihl R; Bachinskaya N; Korczyn AD; Vakhapova V; Tribanek M; Hoerr R; Napryeyenko O; GOTADAY Study Group · International journal of geriatric psychiatry · 2013
    Randomized trial410 participantsCognitive Support forGinkgo
  59. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity.
    Panossian A; Wikman G · Current clinical pharmacology · 2009
    Narrative reviewCognitive Support Mental Focus forRhodiola
  60. Central additive effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy.
    Al-Kuraishy HM · Journal of intercultural ethnopharmacology · 2016
    Clinical trial112 participantsCognitive Support forRhodiola
  61. Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes.
    Łuszczak J; Kocki J · Annals of agricultural and environmental medicine : AAEM · 2026
    Systematic review19 studies pooledCognitive Support forRhodiola
  62. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.
    Olsson EM; von Schéele B; Panossian AG · Planta medica · 2009
    Randomized trial60 participantsCognitive Support Productivity Boost forRhodiola
  63. Combined Effects of Rhodiola Rosea and Caffeine Supplementation on Straight Punch Explosive Power in Untrained and Trained Boxing Volunteers: A Synergistic Approach.
    Tao B; Sun H; Li H; Xu Z; Xu Y; Chen L; Ma C; Zhang X; Yu L; Bao S; Liu C · Metabolites · 2025
    Randomized trial96 participantsEnergy forRhodiola
  64. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  65. Actaea racemosa L. Is More Effective in Combination with Rhodiola rosea L. for Relief of Menopausal Symptoms: A Randomized, Double-Blind, Placebo-Controlled Study.
    Pkhaladze L; Davidova N; Khomasuridze A; Shengelia R; Panossian AG · Pharmaceuticals (Basel, Switzerland) · 2024
    Randomized trial220 participantsGeneral Health forRhodiola
  66. A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen.
    Spasov AA; Wikman GK; Mandrikov VB; Mironova IA; Neumoin VV · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2000
    Randomized trialGeneral Health Productivity Boost forRhodiola
  67. [The effect of the preparation rodakson on the psychophysiological and physical adaptation of students to an academic load].
    Spasov AA; Mandrikov VB; Mironova IA · Eksperimental'naia i klinicheskaia farmakologiia · 2000
    Clinical trialGeneral Health forRhodiola
  68. Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
    Randomized trial40 participantsGeneral Health forVitamin B12
  69. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
    Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
    Randomized trial90 participantsGeneral Health forVitamin B12
  70. A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
    Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
    Randomized trial98 participantsGeneral Health forVitamin B12
  71. Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
    Randomized trial204 participantsGeneral Health forVitamin B12
  72. The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
    Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
    Clinical trial50 participantsGeneral Health forVitamin B12
  73. Evaluating the effects of Bacopa monnieri on cognitive performance and sleep quality of patients with mild cognitive impairment: A triple-blinded, randomized, placebo-controlled trial.
    Delfan M; Kordestani-Moghaddam P; Gholami M; Kazemi K; Mohammadi R · Explore (New York, N.Y.) · 2024
    Randomized trial62 participantsMental Focus forBacopa
  74. Cognitive effects of two nutraceuticals Ginseng and Bacopa benchmarked against modafinil: a review and comparison of effect sizes.
    Neale C; Camfield D; Reay J; Stough C; Scholey A · British journal of clinical pharmacology · 2013
    Systematic reviewMental Focus forBacopa
  75. Efficiency of Different Supplements in Alleviating Symptoms of ADHD with or Without the Use of Stimulants: A Systematic Review.
    Al Shahab S; Al Balushi R; Qambar A; Abdulla R; Qader M; Abdulla S; Jahrami H · Nutrients · 2025
    Systematic reviewMental Focus forBacopa
  76. Ginkgo biloba Extract EGb 761 in the Treatment of Patients with Mild Neurocognitive Impairment: A Systematic Review.
    Hort J; Duning T; Hoerr R · Neuropsychiatric disease and treatment · 2023
    Systematic review946 participants9 studies pooledMental Focus forGinkgo
  77. Proof of efficacy of the Ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia.
    Kanowski S; Herrmann WM; Stephan K; Wierich W; Hörr R · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
    Randomized trial216 participantsMental Focus forGinkgo
  78. Proof of efficacy of the ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia.
    Kanowski S; Herrmann WM; Stephan K; Wierich W; Hörr R · Pharmacopsychiatry · 1996
    Randomized trial216 participantsMental Focus forGinkgo
  79. Ginkgo biloba extract improved cognitive and neurological functions of acute ischaemic stroke: a randomised controlled trial.
    Li S; Zhang X; Fang Q; Zhou J; Zhang M; Wang H; Chen Y; Xu B; Wu Y; Qian L; Xu Y · Stroke and vascular neurology · 2021
    Randomized trial348 participantsMental Focus forGinkgo
  80. Ginkgo biloba in the Aging Process: A Narrative Review.
    Barbalho SM; Direito R; Laurindo LF; Marton LT; Guiguer EL; Goulart RA; Tofano RJ; Carvalho ACA; Flato UAP; Capelluppi Tofano VA; Detregiachi CRP; Bueno PCS; Girio RSJ; Araújo AC · Antioxidants (Basel, Switzerland) · 2024
    Narrative review14 studies pooledMental Focus forGinkgo
  81. The effectiveness and efficacy of Rhodiola rosea L.: a systematic review of randomized clinical trials.
    Hung SK; Perry R; Ernst E · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
    Systematic review11 studies pooledMental Focus forRhodiola
  82. Effects of Rhodiola rosea supplementation on mental performance, physical capacity, and oxidative stress biomarkers in healthy men.
    Jówko E; Sadowski J; Długołęcka B; Gierczuk D; Opaszowski B; Cieśliński I · Journal of sport and health science · 2022
    Randomized trial26 participantsMental Focus Productivity Boost forRhodiola
  83. Associations of one-carbon metabolism, related B-vitamins and ApoE genotype with cognitive function in older adults: identification of a novel gene-nutrient interaction.
    Gordon S; Hoey L; McNulty H; Keenan J; Pangilinan F; Brody LC; Ward M; Strain JJ; McAnena L; McCann A; Molloy AM; Cunningham C; McCarroll K; Hughes CF · BMC medicine · 2025
    Observational study4,553 participantsMental Focus forVitamin B12
  84. Vitamin B12 Levels Association with Functional and Structural Biomarkers of Central Nervous System Injury in Older Adults.
    Beaudry-Richard A; Abdelhak A; Saloner R; Sacco S; Montes SC; Oertel FC; Cordano C; Jabassini N; Ananth K; Gomez A; Keihani A; Chapman M; Javvadi S; Saha S; Staffaroni A; Songster C; Warren M; Boscardin JW; Kramer J; Miller B; Miller JW; Green R; Green AJ · Annals of neurology · 2025
    Cross-sectional study231 participantsMental Focus forVitamin B12
  85. Cobalamin: a critical vitamin in the elderly.
    Wolters M; Ströhle A; Hahn A · Preventive medicine · 2005
    Narrative reviewMental Focus forVitamin B12
  86. The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people.
    Eussen SJ; Ueland PM; Clarke R; Blom HJ; Hoefnagels WH; van Staveren WA; de Groot LC · The British journal of nutrition · 2007
    Randomized trial195 participantsMental Focus forVitamin B12
  87. Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial.
    Calabrese C; Gregory WL; Leo M; Kraemer D; Bone K; Oken B · Journal of alternative and complementary medicine (New York, N.Y.) · 2009
    Randomized trial54 participantsProductivity Boost forBacopa
  88. Examining the nootropic effects of a special extract of Bacopa monniera on human cognitive functioning: 90 day double-blind placebo-controlled randomized trial.
    Stough C; Downey LA; Lloyd J; Silber B; Redman S; Hutchison C; Wesnes K; Nathan PJ · Phytotherapy research : PTR · 2009
    Randomized trial107 participantsProductivity Boost forBacopa
  89. An acute, double-blind, placebo-controlled crossover study of 320 mg and 640 mg doses of a special extract of Bacopa monnieri (CDRI 08) on sustained cognitive performance.
    Downey LA; Kean J; Nemeh F; Lau A; Poll A; Gregory R; Murray M; Rourke J; Patak B; Pase MP; Zangara A; Lomas J; Scholey A; Stough C · Phytotherapy research : PTR · 2014
    Randomized trial24 participantsProductivity Boost forBacopa
  90. [Ginkgo biloba extract EGb 761 in the treatment of dementia: evidence of efficacy and tolerability].
    Kasper S; Schubert H · Fortschritte der Neurologie-Psychiatrie · 2009
    Meta-analysis10 studies pooledProductivity Boost forGinkgo
  91. Dietary Flavonoids and Human Cognition: A Meta-Analysis.
    Cheng N; Bell L; Lamport DJ; Williams CM · Molecular nutrition & food research · 2022
    Meta-analysis5,519 participants80 studies pooledProductivity Boost forGinkgo
  92. Limited cognitive benefits in Stage +2 postmenopausal women after 6 weeks of treatment with Ginkgo biloba.
    Elsabagh S; Hartley DE; File SE · Journal of psychopharmacology (Oxford, England) · 2005
    Randomized trial87 participantsProductivity Boost forGinkgo
  93. Efficacy and safety of Ginkgo biloba extract EGb 761 in mild cognitive impairment with neuropsychiatric symptoms: a randomized, placebo-controlled, double-blind, multi-center trial.
    Gavrilova SI; Preuss UW; Wong JW; Hoerr R; Kaschel R; Bachinskaya N; GIMCIPlus Study Group · International journal of geriatric psychiatry · 2015
    Randomized trial160 participantsProductivity Boost forGinkgo
  94. Modulation of cognitive performance following single doses of 120 mg Ginkgo biloba extract administered to healthy young volunteers.
    Kennedy DO; Jackson PA; Haskell CF; Scholey AB · Human psychopharmacology · 2008
    Randomized trial78 participantsProductivity Boost forGinkgo
  95. The Effectiveness of Rhodiola rosea L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions-Encouraging Clinical Evidence.
    Ivanova Stojcheva E; Quintela JC · Molecules (Basel, Switzerland) · 2022
    Narrative reviewProductivity Boost forRhodiola
  96. Effects of Folic Acid and Vitamin B12, Alone and in Combination on Cognitive Function and Inflammatory Factors in the Elderly with Mild Cognitive Impairment: A Single-blind Experimental Design.
    Ma F; Zhou X; Li Q; Zhao J; Song A; An P; Du Y; Xu W; Huang G · Current Alzheimer research · 2020
    Randomized trial240 participantsProductivity Boost forVitamin B12
  97. Effects of Physical Activity and Micronutrients on Cognitive Performance in Children Aged 6 to 11 Years: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Meli AM; Ali A; Mhd Jalil AM; Mohd Yusof H; Tan MMC · Medicina (Kaunas, Lithuania) · 2022
    Meta-analysisProductivity Boost forVitamin B12
  98. Cognitive function in an elderly population: interaction between vitamin B12 status, depression, and apolipoprotein E ε4: the Hordaland Homocysteine Study.
    Vogiatzoglou A; Smith AD; Nurk E; Drevon CA; Ueland PM; Vollset SE; Nygaard HA; Engedal K; Tell GS; Refsum H · Psychosomatic medicine · 2013
    Cross-sectional study1,935 participantsProductivity Boost forVitamin B12
  99. Cognitive profile and inflammatory markers in children and adolescents with specific learning disorder: a cross-sectional study.
    Balatacı U; Ay B · Frontiers in pediatrics · 2026
    Case-control study108 participantsProductivity Boost forVitamin B12
  100. Association between vitamin B12 levels and cognitive impairment in older adults.
    Aguilar-Navarro SG; Carbajal-Silva JC; Palacios-Hernández MGI; Gutiérrez-Gutierrez LA; Ávila-Funes JA; Mimenza-Alvarado AJ · Gaceta medica de Mexico · 2023
    Cross-sectional study241 participantsProductivity Boost forVitamin B12
  101. Effects of vitamin B12 on performance and circadian rhythm in normal subjects.
    Mayer G; Kröger M; Meier-Ewert K · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 1997
    Randomized trial20 participantsProductivity Boost forVitamin B12
  102. Prenatal vitamin B12 status and cognitive functioning in children at 4 years of age: The ECLIPSES Study.
    Cruz-Rodríguez J; Canals-Sans J; Hernández-Martínez C; Voltas-Moreso N; Arija V · Maternal & child nutrition · 2023
    Cohort study249 participantsProductivity Boost forVitamin B12
  103. Dietary intakes and biomarker patterns of folate, vitamin B6, and vitamin B12 can be associated with cognitive impairment by hypermethylation of redox-related genes NUDT15 and TXNRD1.
    An Y; Feng L; Zhang X; Wang Y; Wang Y; Tao L; Qin Z; Xiao R · Clinical epigenetics · 2020
    Cohort study2,533 participantsProductivity Boost forVitamin B12
  104. Homocysteine, folate, and vitamins B6 and B12 blood levels in relation to cognitive performance: the Maine-Syracuse study.
    Elias MF; Robbins MA; Budge MM; Elias PK; Brennan SL; Johnston C; Nagy Z; Bates CJ · Psychosomatic medicine · 2008
    Cross-sectional study812 participantsProductivity Boost forVitamin B12