Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Efficacy of Ginkgo biloba extract EGb 761® in dementia with behavioural and psychological symptoms: A systematic review.
von Gunten A; Schlaefke S; Überla K · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2017
Meta-analysis1,628 participants4 studies pooledflagCognitive Support flagBrain Health forscienceGinkgo
- Ginkgo biloba for cognitive impairment and dementia.
Wieland LS; Ludeman E; Chi Y; Feinberg TM; Chen IH; Chen KH; Zhu Y; Wolverson E; Amri H · The Cochrane database of systematic reviews · 2026
Meta-analysis10,613 participants82 studies pooledflagCognitive Support forscienceGinkgo
- Ginkgo biloba Extract (EGb761), Cholinesterase Inhibitors, and Memantine for the Treatment of Mild-to-Moderate Alzheimer's Disease: A Network Meta-Analysis.
Thancharoen O; Limwattananon C; Waleekhachonloet O; Rattanachotphanit T; Limwattananon P; Limpawattana P · Drugs & aging · 2019
Meta-analysisflagCognitive Support forscienceGinkgo
- Acetyl-L-carnitine treatment in minimal hepatic encephalopathy.
Malaguarnera M; Gargante MP; Cristaldi E; Vacante M; Risino C; Cammalleri L; Pennisi G; Rampello L · Digestive diseases and sciences · 2008
Randomized trial125 participantsflagCognitive Support flagBrain Health forscienceAcetyl L-Carnitine
- Long-term acetyl-L-carnitine treatment in Alzheimer's disease.
Spagnoli A; Lucca U; Menasce G; Bandera L; Cizza G; Forloni G; Tettamanti M; Frattura L; Tiraboschi P; Comelli M · Neurology · 1991
Randomized trial130 participantsflagCognitive Support flagBrain Health forscienceAcetyl L-Carnitine
- A 1-year controlled trial of acetyl-l-carnitine in early-onset AD.
Thal LJ; Calvani M; Amato A; Carta A · Neurology · 2000
Randomized trial229 participantsflagCognitive Support forscienceAcetyl L-Carnitine
- Acetyl L-carnitine slows decline in younger patients with Alzheimer's disease: a reanalysis of a double-blind, placebo-controlled study using the trilinear approach.
Brooks JO; Yesavage JA; Carta A; Bravi D · International psychogeriatrics · 1998
Randomized trial334 participantsflagCognitive Support forscienceAcetyl L-Carnitine
- Acetyl-L-carnitine Slows the Progression from Prefrailty to Frailty in Older Subjects: A Randomized Interventional Clinical Trial.
Malaguarnera G; Catania VE; Bertino G; Chisari LM; Castorina M; Bonfiglio C; Cauli O; Malaguarnera M · Current pharmaceutical design · 2022
Randomized trial92 participantsflagAnti-Aging forscienceAcetyl L-Carnitine
- Pharmaco-electroencephalographic and clinical effects of the cholinergic substance--acetyl-L-carnitine--in patients with organic brain syndrome.
Herrmann WM; Dietrich B; Hiersemenzel R · International journal of clinical pharmacology research · 1990
Randomized trialflagBrain Health forscienceAcetyl L-Carnitine
- Acetyl-L-carnitine improves cognitive functions in severe hepatic encephalopathy: a randomized and controlled clinical trial.
Malaguarnera M; Vacante M; Motta M; Giordano M; Malaguarnera G; Bella R; Nunnari G; Rampello L; Pennisi G · Metabolic brain disease · 2012
Randomized trial61 participantsflagBrain Health flagCognitive Support forscienceAcetyl L-Carnitine
- Acetyl-L-carnitine in the treatment of mildly demented elderly patients.
Passeri M; Cucinotta D; Bonati PA; Iannuccelli M; Parnetti L; Senin U · International journal of clinical pharmacology research · 1990
Randomized trial60 participantsflagBrain Health flagMental Focus forscienceAcetyl L-Carnitine
- Efficacy and adverse effects of ginkgo biloba for cognitive impairment and dementia: a systematic review and meta-analysis.
Tan MS; Yu JT; Tan CC; Wang HF; Meng XF; Wang C; Jiang T; Zhu XC; Tan L · Journal of Alzheimer's disease : JAD · 2015
Meta-analysis2,561 participants9 studies pooledflagBrain Health forscienceGinkgo
- Ginkgo biloba extract EGb 761 is safe and effective in the treatment of mild dementia - a meta-analysis of patient subgroups in randomised controlled trials.
Riepe M; Hoerr R; Schlaefke S · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2025
Meta-analysis782 participants4 studies pooledflagBrain Health flagProductivity Boost forscienceGinkgo
- Ginkgo biloba extract EGb 761® improves cognition and overall condition after ischemic stroke: Results from a pilot randomized trial.
Cui M; You T; Zhao Y; Liu R; Guan Y; Liu J; Liu X; Wang X; Dong Q · Frontiers in pharmacology · 2023
Randomized trial201 participantsflagBrain Health flagProductivity Boost forscienceGinkgo
- Ginkgo biloba extract EGb 761® in dementia with neuropsychiatric features: a randomised, placebo-controlled trial to confirm the efficacy and safety of a daily dose of 240 mg.
Herrschaft H; Nacu A; Likhachev S; Sholomov I; Hoerr R; Schlaefke S · Journal of psychiatric research · 2012
Randomized trial410 participantsflagBrain Health forscienceGinkgo
- A double-blind, parallel, multicenter comparison of L-acetylcarnitine with placebo on the attention deficit hyperactivity disorder in fragile X syndrome boys.
Torrioli MG; Vernacotola S; Peruzzi L; Tabolacci E; Mila M; Militerni R; Musumeci S; Ramos FJ; Frontera M; Sorge G; Marzullo E; Romeo G; Vallee L; Veneselli E; Cocchi E; Garbarino E; Moscato U; Chiurazzi P; D'Iddio S; Calvani M; Neri G · American journal of medical genetics. Part A · 2008
Randomized trial63 participantsflagCognitive Support forscienceAcetyl L-Carnitine
- Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue.
Malaguarnera M; Gargante MP; Cristaldi E; Colonna V; Messano M; Koverech A; Neri S; Vacante M; Cammalleri L; Motta M · Archives of gerontology and geriatrics · 2008
Randomized trial96 participantsflagCognitive Support forscienceAcetyl L-Carnitine
- Senile dementia: treatment with deanol.
Ferris SH; Sathananthan G; Gershon S; Clark C · Journal of the American Geriatrics Society · 1977
Single-arm trial14 participantsflagCognitive Support forscienceDeanol
- Effects of dimethylaminoethanol pyroglutamate (DMAE p-Glu) against memory deficits induced by scopolamine: evidence from preclinical and clinical studies.
Blin O; Audebert C; Pitel S; Kaladjian A; Casse-Perrot C; Zaim M; Micallef J; Tisne-Versailles J; Sokoloff P; Chopin P; Marien M · Psychopharmacology · 2010
Randomized trial24 participantsflagCognitive Support forscienceDeanol
- Efficacy of ginkgo diterpene lactone meglumine on cognitive function in patients with acute ischemic stroke: a predefined exploratory analysis of a multicenter, double-blind, randomized controlled trial.
Tian X; Xu Q; Xia X; Zhang Y; Meng X; Wang A · Journal of neurology · 2024
Randomized trial3,163 participantsflagCognitive Support forscienceGinkgo
- A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group.
Le Bars PL; Katz MM; Berman N; Itil TM; Freedman AM; Schatzberg AF · JAMA · 1997
Randomized trial309 participantsflagCognitive Support flagProductivity Boost forscienceGinkgo
- Alleviating neuropsychiatric symptoms in dementia: the effects of Ginkgo biloba extract EGb 761. Findings from a randomized controlled trial.
Bachinskaya N; Hoerr R; Ihl R · Neuropsychiatric disease and treatment · 2011
Randomized trial410 participantsflagCognitive Support forscienceGinkgo
- Efficacy and safety of a once-daily formulation of Ginkgo biloba extract EGb 761 in dementia with neuropsychiatric features: a randomized controlled trial.
Ihl R; Bachinskaya N; Korczyn AD; Vakhapova V; Tribanek M; Hoerr R; Napryeyenko O; GOTADAY Study Group · International journal of geriatric psychiatry · 2013
Randomized trial410 participantsflagCognitive Support forscienceGinkgo
- Oral acetyl-L-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study.
Malaguarnera M; Vacante M; Giordano M; Pennisi G; Bella R; Rampello L; Malaguarnera M; Li Volti G; Galvano F · The American journal of clinical nutrition · 2011
Randomized trial121 participantsflagEnergy forscienceAcetyl L-Carnitine
- The supplementation of acetyl-L-carnitine decreases fatigue and increases quality of life in patients with hepatitis C treated with pegylated interferon-α 2b plus ribavirin.
Malaguarnera M; Vacante M; Bertino G; Neri S; Malaguarnera M; Gargante MP; Motta M; Lupo L; Chisari G; Bruno CM; Pennisi G; Bella R · Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2012
Randomized trial60 participantsflagEnergy forscienceAcetyl L-Carnitine
- Acetyl-L-carnitine reduces depression and improves quality of life in patients with minimal hepatic encephalopathy.
Malaguarnera M; Bella R; Vacante M; Giordano M; Malaguarnera G; Gargante MP; Motta M; Mistretta A; Rampello L; Pennisi G · Scandinavian journal of gastroenterology · 2011
Randomized trial67 participantsflagEnergy forscienceAcetyl L-Carnitine
- A prospective study to evaluate the efficacy and safety of oral acetyl-L-carnitine for the treatment of chemotherapy-induced peripheral neuropathy.
Sun Y; Shu Y; Liu B; Liu P; Wu C; Zheng R; Zhang X; Zhuang Z; Deng Y; Zheng L; Xu Q; Jiang B; Ouyang X; Gao J; Xu N; Li X; Jiang S; Liang C; Yao Y · Experimental and therapeutic medicine · 2020
Randomized trial239 participantsflagEnergy forscienceAcetyl L-Carnitine
- Metabolomic biomarkers for (R, S)-ketamine and (S)-ketamine in treatment-resistant depression and healthy controls: A systematic review.
Kumar R; Nuñez NA; Joshi N; Joseph B; Verde A; Seshadri A; Cuellar Barboza AB; Prokop LJ; Medeiros GC; Singh B · Bipolar disorders · 2024
Systematic reviewflagEnergy forscienceAcetyl L-Carnitine
- Acetyl-L-Carnitine Supplementation During HCV Therapy With Pegylated Interferon-α 2b Plus Ribavirin: Effect on Work Performance; A Randomized Clinical Trial.
Malaguarnera G; Pennisi M; Gagliano C; Vacante M; Malaguarnera M; Salomone S; Drago F; Bertino G; Caraci F; Nunnari G; Malaguarnera M · Hepatitis monthly · 2014
Randomized trial62 participantsflagMental Focus flagProductivity Boost forscienceAcetyl L-Carnitine
- [Psycho-functional changes in attention and learning under the action of L-acetylcarnitine in 17 young subjects. A pilot study of its use in mental deterioration].
Lino A; Boccia MM; Rusconi AC; Bellomonte L; Cocuroccia B · La Clinica terapeutica · 1992
Non-randomized trial17 participantsflagMental Focus forscienceAcetyl L-Carnitine
- Acetyl-L-carnitine (ALC) in attention-deficit/hyperactivity disorder: a multi-site, placebo-controlled pilot trial.
Arnold LE; Amato A; Bozzolo H; Hollway J; Cook A; Ramadan Y; Crowl L; Zhang D; Thompson S; Testa G; Kliewer V; Wigal T; McBurnett K; Manos M · Journal of child and adolescent psychopharmacology · 2008
Randomized trial112 participantsflagMental Focus forscienceAcetyl L-Carnitine
- Acetyl-L-carnitine for patients with hepatic encephalopathy.
Martí-Carvajal AJ; Gluud C; Arevalo-Rodriguez I; Martí-Amarista CE · The Cochrane database of systematic reviews · 2019
Meta-analysis398 participants5 studies pooledflagMental Focus forscienceAcetyl L-Carnitine
- Ginkgo biloba Extract EGb 761 in the Treatment of Patients with Mild Neurocognitive Impairment: A Systematic Review.
Hort J; Duning T; Hoerr R · Neuropsychiatric disease and treatment · 2023
Systematic review946 participants9 studies pooledflagMental Focus forscienceGinkgo
- Proof of efficacy of the Ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia.
Kanowski S; Herrmann WM; Stephan K; Wierich W; Hörr R · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
Randomized trial216 participantsflagMental Focus forscienceGinkgo
- Proof of efficacy of the ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia.
Kanowski S; Herrmann WM; Stephan K; Wierich W; Hörr R · Pharmacopsychiatry · 1996
Randomized trial216 participantsflagMental Focus forscienceGinkgo
- Ginkgo biloba extract improved cognitive and neurological functions of acute ischaemic stroke: a randomised controlled trial.
Li S; Zhang X; Fang Q; Zhou J; Zhang M; Wang H; Chen Y; Xu B; Wu Y; Qian L; Xu Y · Stroke and vascular neurology · 2021
Randomized trial348 participantsflagMental Focus forscienceGinkgo
- Ginkgo biloba in the Aging Process: A Narrative Review.
Barbalho SM; Direito R; Laurindo LF; Marton LT; Guiguer EL; Goulart RA; Tofano RJ; Carvalho ACA; Flato UAP; Capelluppi Tofano VA; Detregiachi CRP; Bueno PCS; Girio RSJ; Araújo AC · Antioxidants (Basel, Switzerland) · 2024
Narrative review14 studies pooledflagMental Focus forscienceGinkgo
- Low Bioavailability and High TMAO Production: Novel Insights Into Acetylcarnitine and Carnitine Metabolism.
Krims-Davis K; Ozola M; Razzivina V; Gukalova B; Konrade I; Dambrova M; Liepinsh E · Molecular nutrition & food research · 2025
Randomized trialflagMetabolism Boost forscienceAcetyl L-Carnitine
- [Ginkgo biloba extract EGb 761 in the treatment of dementia: evidence of efficacy and tolerability].
Kasper S; Schubert H · Fortschritte der Neurologie-Psychiatrie · 2009
Meta-analysis10 studies pooledflagProductivity Boost forscienceGinkgo
- Dietary Flavonoids and Human Cognition: A Meta-Analysis.
Cheng N; Bell L; Lamport DJ; Williams CM · Molecular nutrition & food research · 2022
Meta-analysis5,519 participants80 studies pooledflagProductivity Boost forscienceGinkgo
- Limited cognitive benefits in Stage +2 postmenopausal women after 6 weeks of treatment with Ginkgo biloba.
Elsabagh S; Hartley DE; File SE · Journal of psychopharmacology (Oxford, England) · 2005
Randomized trial87 participantsflagProductivity Boost forscienceGinkgo
- Efficacy and safety of Ginkgo biloba extract EGb 761 in mild cognitive impairment with neuropsychiatric symptoms: a randomized, placebo-controlled, double-blind, multi-center trial.
Gavrilova SI; Preuss UW; Wong JW; Hoerr R; Kaschel R; Bachinskaya N; GIMCIPlus Study Group · International journal of geriatric psychiatry · 2015
Randomized trial160 participantsflagProductivity Boost forscienceGinkgo
- Modulation of cognitive performance following single doses of 120 mg Ginkgo biloba extract administered to healthy young volunteers.
Kennedy DO; Jackson PA; Haskell CF; Scholey AB · Human psychopharmacology · 2008
Randomized trial78 participantsflagProductivity Boost forscienceGinkgo