Vitamin D3 25 mcg (1000 IU) & K2 120 mcg
Natural Factors
Vitamin D3 25 mcg (1000 IU) & K2 120 mcg
4.8
★ ★ ★ ★ ★
(3103 ratings)
Vitamin K 120 mcg
Score 88.0
This product effectively combines Vitamin D3 (1000 IU) with optimal K2 MK-7 (120mcg from Natto) for synergistic bone and cardiovascular health benefits. It offers a well-balanced formulation at a very good price, making it a strong value. While the D3 dose is foundational, it's a solid choice.
Quantity: 60 Softgel(s)Servings size: 1 Softgel(s) (60 servings)
Selected goals:
Other goals:
Bone Health
Heart Health
Cardiovascular Support
General Health
leaderboard Score 88.0
This product effectively combines Vitamin D3 (1000 IU) with optimal K2 MK-7 (120mcg from Natto) for synergistic bone and cardiovascular health benefits. It offers a well-balanced formulation at a very good price, making it a strong value. While the D3 dose is foundational, it's a solid choice.
insights Analysis
This Natural Factors supplement is a highly commendable choice for those seeking integrated bone and cardiovascular support. It combines Vitamin D3, essential for calcium absorption, with Vitamin K2 (Menaquinone-7 from Natto), vital for directing that calcium to bones and away from arteries. The 120mcg of MK-7 is an optimal dose, and while 1000 IU of D3 is a good foundational dose, some individuals may require higher levels. Overall, its reasonable price per serving makes it an accessible and effective option for daily health maintenance, earning positive reviews for its beneficial formulation.
- Offers a synergistic combination of Vitamin D3 and highly bioavailable Vitamin K2 (MK-7).
- Provides an optimal 120mcg dose of MK-7 for effective bone and cardiovascular support.
- Derived from Natto, ensuring a natural and well-recognized source of MK-7.
- Excellent price per serving, delivering strong value for a combined supplement.
- The 1000 IU dosage of Vitamin D3 might be insufficient for individuals with significant deficiency or higher daily needs.
$20.97($0.34 per serving)
 iHerb | $ 20.97 | |
 Vitacost | $ 20.97 |
bolt Effectiveness for goals
Vitamin K is essential for proper blood clotting and plays a significant role in bone metabolism. It helps the body produce proteins necessary for these vital bodily functions.
Vitamin K activates proteins such as osteocalcin, which are crucial for incorporating calcium into the bone matrix. This mechanism supports bone mineralization and helps maintain bone density.
Vitamin K1 (phylloquinone) is primarily effective for blood coagulation and is abundant in green leafy vegetables. Vitamin K2 (menaquinones) is more involved in bone and cardiovascular health, found in fermented foods and animal products, and has different bioavailabilities.
Emerging research suggests that Vitamin K, particularly K2, may help prevent arterial calcification by activating matrix Gla protein. This protein helps inhibit calcium deposition in soft tissues, supporting arterial flexibility.
Vitamin K works synergistically with calcium by helping to direct calcium to the bones and away from soft tissues like arteries. It activates proteins like osteocalcin for bone binding and matrix Gla protein to inhibit soft tissue calcification.
schedule Dosage, timing & forms
Recommended dosages for Vitamin K vary by age and form (K1 vs K2). For adults, the Adequate Intake (AI) for Vitamin K is 120 mcg per day for men and 90 mcg per day for women. Specific supplemental dosages may differ depending on individual needs and health goals.
Yes, dosages can differ between Vitamin K1 and K2 due to their varying potencies and half-lives. While K1 is measured in micrograms (mcg) for general intake, K2 (especially MK-7) may be effective at lower microgram doses due to its longer half-life. It's important to check the specific form and dosage on the supplement label.
Yes, Vitamin K is a fat-soluble vitamin, meaning it is best absorbed when taken with a meal containing some dietary fat. This helps facilitate its absorption into the body.
The two main forms of Vitamin K found in supplements are Vitamin K1 (phylloquinone) and Vitamin K2 (menaquinone). Vitamin K2 further has various subtypes, with MK-4 and MK-7 being the most common in supplements. Each form may have distinct roles and bioavailability.
There is no established Upper Limit (UL) for Vitamin K from food or supplements, as toxicity is rare. However, high doses of synthetic Vitamin K (menadione, K3) can be toxic, though this form is not typically found in supplements. Always adhere to recommended dosages and consult a healthcare provider if you have concerns.
health_and_safety Safety & interactions
Vitamin K plays a crucial role in blood clotting, which is the opposite effect of anticoagulant medications such as warfarin. Consuming inconsistent amounts of Vitamin K can alter warfarin's effectiveness, potentially making the blood thinner less effective or increasing bleeding risk. Individuals taking warfarin should maintain a consistent intake of Vitamin K and consult their healthcare provider.
Individuals taking anticoagulant medications like warfarin should consult their doctor before taking Vitamin K supplements due to potential interactions. People with certain liver conditions or those with a G6PD deficiency should also seek medical advice before supplementation. Always discuss new supplements with a healthcare provider.
Vitamin K supplements are generally considered safe for most healthy individuals when taken at recommended dosages. Side effects are uncommon but can include upset stomach, diarrhea, or allergic reactions in sensitive individuals. High doses of synthetic Vitamin K (menadione, K3) can be toxic, but this form is rarely used in supplements.
Vitamin K is essential during pregnancy and breastfeeding, and adequate intake is important for both mother and child. However, supplementation during these periods should only be undertaken under the guidance of a healthcare professional. High doses are generally not recommended without specific medical advice.
There is currently no established Tolerable Upper Intake Level (UL) for Vitamin K from food or supplements due to its low potential for toxicity. However, excessive intake, especially of synthetic forms, could potentially have adverse effects. It is always best to adhere to recommended dosages on supplement labels or as advised by a healthcare professional.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin D3 | 25 mcg |
Vitamin K2 | 120 mcg |
Categories
Vitamin K 90.0
Within the Vitamin K collection, this product stands out due to its inclusion of the superior MK-7 form, derived from Natto, combined with the essential cofactor Vitamin D3, making it a highly effective and well-rounded Vitamin K supplement for its stated goals.
Goals
Bone Health 90.0
The synergistic action of D3 (aiding calcium absorption) and K2 MK-7 (directing calcium to bones) makes this product highly effective for bone health, supporting density and strength. The optimal K2 dose is key for this mechanism.
Heart Health 88.0
The combination of D3 and K2 MK-7 is crucial for heart health, as K2 prevents arterial calcification while D3 supports overall cardiovascular function. This product provides an effective dose of both for robust heart support.
By including both D3 and MK-7, this supplement efficiently supports cardiovascular health by facilitating proper calcium utilization and preventing its undesirable deposition in arteries. This comprehensive approach contributes significantly to arterial flexibility.
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