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Gamma E 400

Source Naturals
4.7
★ ★ ★ ★ ★
(457 ratings)
Vitamin E 190 IU
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Score74
Broad natural vitamin E coverage is the standout strength, with isomer opacity, sesame, and bleeding risk as important limits.
How scoring works
Quantity:60 Softgel(s) • (60 servings)
Goals:
Anti-Inflammatory Support
Cardiovascular Support

Score 74

Broad natural vitamin E coverage is the standout strength, with isomer opacity, sesame, and bleeding risk as important limits.
How scoring works
$29.50($0.49 per serving)
iHerb
$ 29.50
iHerb
$ 29.50
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Analysis

The formula pairs natural d-alpha-tocopherol with a large tocopherol blend and a tocotrienol complex. That combination provides broader vitamin E-family coverage than products built around alpha-tocopherol alone.

Individual isomer amounts are not disclosed, so the exact balance of gamma, delta, and other forms cannot be judged. The tocotrienol amount is also modest beside the larger tocopherol blend.

Softgel delivery and sesame oil support fat-soluble delivery, while the one-softgel serving is convenient. Sesame makes the product unsuitable for people with that allergy, and substantial vitamin E intake requires care with blood-thinning medicines.

Who is it for
  • Adults seeking tocopherols and tocotrienols
  • Users wanting broad vitamin E-family support
  • People without sesame allergy
Best for
  • Comprehensive vitamin E intake
  • Lipid antioxidant support
  • Anti-inflammatory antioxidant coverage

Pros

  • Natural alpha-tocopherol
  • Large tocopherol blend
  • Includes tocotrienols
  • Softgel delivery

Cons

  • Individual isomers are not quantified
  • Tocotrienol amount is modest
  • Contains sesame oil
  • Premium serving cost

Warnings

  • Avoid the product if you have a sesame allergy because it contains sesame seed oil.
  • The substantial vitamin E profile may increase bleeding with anticoagulant or antiplatelet medicines.

Nutrient quality

88 Highest impact

Natural tocopherols and tocotrienols provide broad vitamin E support at meaningful amounts. Hidden isomer doses and a sesame allergen remain important limitations.

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Ingredient transparency

63 Moderate impact

Active ingredients and their amounts are mostly clear without a hidden proprietary total. Daily directions and a complete other-ingredients panel are not included in the supplied data.

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Customer satisfaction

66 High impact

The aggregate rating is favorable and supported by moderate feedback volume. Complaint-level experiences are unavailable, so repeated drawbacks and purpose fit remain uncertain.

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Value for money

78 High impact

The formula offers useful actives at a relatively high serving cost. Quality or disclosure limits weaken category competitiveness.

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Goals

Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Highest effect
B+ Goal FitA- Strength of SupportB- CoverageA Formula Quality
Vitamin E · 190 IU

Natural alpha-tocopherol, a mixed tocopherol blend, and tocotrienols provide broad vitamin E antioxidant coverage. These forms protect cell membranes from oxidative damage that can sustain inflammation, although they do not directly cover fatty-acid or immune-regulating pathways.

The total vitamin E profile is substantial, but individual blend isomers and tocotrienols are not fully quantified. Sesame oil is a specific allergen concern, so people with sesame allergy should avoid the formula.

Study evidence
Vitamin E Supportive 20 studies
Cardiovascular Support
Cardiovascular Support
Impact
High effect
C Goal FitA- Strength of SupportD+ CoverageA Formula Quality
Vitamin E · 190 IU

Natural alpha-tocopherol, mixed tocopherols, and tocotrienols provide broad lipid-phase antioxidant support. They may protect lipoproteins from oxidation, but vitamin E supplementation has not consistently improved cardiovascular outcomes.

The softgel and sesame oil suit this fat-soluble vitamin, while individual blend isomers are not quantified. High-dose vitamin E may increase bleeding with anticoagulant or antiplatelet medicines, and sesame oil is unsuitable for people with sesame allergy.

Study evidence
Vitamin E Mixed 79 studies

Ingredients

IngredientAmount per serving
Vitamin E (D-Alpha-Tocopherol)
 190 IU
Tocopherol Blend
667 mg
Sesame seed Oil
30 mg
Tocotrienol Complex
5 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
Vitamin E (D-Alpha-Tocopherol) · 190 IU OverallScore82
B+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB- Value
The natural d-alpha form, added tocopherol blend, and tocotrienol complex provide broader vitamin E coverage than alpha-tocopherol alone. The dose fits the preferred therapeutic range, though the blend does not disclose individual isomer amounts. Sesame seed oil creates a specific allergen concern for people with a sesame allergy.
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81 Performance

Natural E-400

Protocol For Life Balance
<p>Natural vitamin E, three named mixed tocopherols, and selenium form a transparent antioxidant combination. Compared with Gamma E 400, its fully disclosed mixed tocopherols and selenium may address the original's opaque tocopherol blend and sesame-allergy concern more directly, although the vitamin E amount is high for routine use.</p>
78 Performance

Natural E-Complex With Mixed Tocopherols 400 IU

Country Life
<p>Four named natural tocopherol isomers provide broader vitamin E family coverage than alpha-tocopherol alone. Compared with Gamma E 400, its broad tocopherol profile may address the original's opaque tocopherol blend and sesame-allergy concern more directly, although the repeated equal amount entries make the true total uncertain.</p>
83 Performance

Vitamin E Complete

OL Olympian Labs
<p>Natural d-alpha-tocopherol and mixed tocotrienols create balanced vitamin E family coverage at a practical amount. Compared with Gamma E 400, its balanced tocopherol-and-tocotrienol design may address the original's opaque tocopherol blend and sesame-allergy concern more directly, although the individual tocotrienol isomers are not quantified.</p>
83 Budget

Natural E Liquid

NOW
<p>A modest natural d-alpha-tocopherol amount offers a lower-intensity maintenance option in liquid form. Its lower recurring cost than Gamma E 400 supports this category, although the formula is alpha-only and daily directions are absent.</p>
68 Budget

Collagen

Sanar Naturals
<p>Natural-form vitamin E is paired with vitamin C and hydrolyzed collagen in a concise formula. Its lower recurring cost than Gamma E 400 supports this category, although the collagen blend is below common gram-level servings and is not a dedicated vitamin E formula.</p>
84 Budget

Mixed Vitamin E 400 IU

Natural Factors
<p>Natural d-alpha-tocopherol with mixed tocopherols gives broader antioxidant coverage than alpha alone. Its lower recurring cost than Gamma E 400 supports this category, although the substantial vitamin E amount warrants care with anticoagulant or antiplatelet medicines.</p>
79 Value

Kyolic Vitamin E Cayenne Hawthorn

Kyolic
<p>Natural-form vitamin E is paired with aged garlic, hawthorn, and cayenne for broader cardiovascular support. Compared with Gamma E 400, its lower recurring cost and its vitamin E and clearly stated cardiovascular botanicals create a more favorable quality-to-cost balance, although the combination may increase bleeding tendency with anticoagulant or antiplatelet medicines.</p>
85 Value

Natural E-Oil

NOW
<p>Natural d-alpha-tocopherol provides a practical antioxidant amount in a concentrated liquid. Compared with Gamma E 400, its lower recurring cost and its clearly stated natural vitamin E amount create a more favorable quality-to-cost balance, although the formula is alpha-only and daily intake directions are absent.</p>
84 Value

Coenzyme Q10 100 mg

Source Naturals
<p>Clearly identified ubiquinone is paired with a small natural vitamin E amount in a short formula. Compared with Gamma E 400, its lower recurring cost and its transparent coenzyme Q10 form and focused ingredient list create a more favorable quality-to-cost balance, although the vitamin E contribution is minor.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
    Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
    Randomized trial110 participantsAnti-Inflammatory Support forVitamin E
  2. Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
    Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
    Meta-analysis495 participants12 studies pooledAnti-Inflammatory Support forVitamin E
  3. Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
    Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
    Meta-analysis46 studies pooledAnti-Inflammatory Support forVitamin E
  4. Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
    Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
    Meta-analysis8 studies pooledAnti-Inflammatory Support forVitamin E
  5. Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
    Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
    Randomized trial71 participantsAnti-Inflammatory Support forVitamin E
  6. Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis.
    Loffredo L; Perri L; Di Castelnuovo A; Iacoviello L; De Gaetano G; Violi F · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2016
    Meta-analysis16 studies pooledCardiovascular Support forVitamin E
  7. Vitamin E ameliorates blood cholesterol level and alters gut microbiota composition: A randomized controlled trial.
    Chen B; Li Y; Li Z; Hu X; Zhen H; Chen H; Nie C; Hou Y; Zhu S; Xiao L; Li T · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2025
    Randomized trial90 participantsCardiovascular Support forVitamin E
  8. Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial.
    Lonn E; Bosch J; Yusuf S; Sheridan P; Pogue J; Arnold JM; Ross C; Arnold A; Sleight P; Probstfield J; Dagenais GR; HOPE and HOPE-TOO Trial Investigators · JAMA · 2005
    Randomized trial9,541 participantsCardiovascular Support forVitamin E
  9. Independent and combined associations of dietary antioxidant exposure with all-cause and cause-specific mortality in the general population.
    Liu Z; He Z; Xing Y · Journal of nutritional science · 2026
    Cohort study34,955 participantsCardiovascular Support forVitamin E
  10. Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study.
    Chin SF; Ibahim J; Makpol S; Abdul Hamid NA; Abdul Latiff A; Zakaria Z; Mazlan M; Mohd Yusof YA; Abdul Karim A; Wan Ngah WZ · Nutrition & metabolism · 2011
    Randomized trial62 participantsCardiovascular Support forVitamin E