Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Efficacy and adverse effects of ginkgo biloba for cognitive impairment and dementia: a systematic review and meta-analysis.
Tan MS; Yu JT; Tan CC; Wang HF; Meng XF; Wang C; Jiang T; Zhu XC; Tan L · Journal of Alzheimer's disease : JAD · 2015
Meta-analysis2,561 participants9 studies pooledflagBrain Health forscienceGinkgo
- Efficacy of Ginkgo biloba extract EGb 761® in dementia with behavioural and psychological symptoms: A systematic review.
von Gunten A; Schlaefke S; Überla K · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2017
Meta-analysis1,628 participants4 studies pooledflagCognitive Support flagBrain Health forscienceGinkgo
- Acetyl-L-carnitine treatment in minimal hepatic encephalopathy.
Malaguarnera M; Gargante MP; Cristaldi E; Vacante M; Risino C; Cammalleri L; Pennisi G; Rampello L · Digestive diseases and sciences · 2008
Randomized trial125 participantsflagCognitive Support flagBrain Health forscienceAcetyl L-Carnitine
- Long-term acetyl-L-carnitine treatment in Alzheimer's disease.
Spagnoli A; Lucca U; Menasce G; Bandera L; Cizza G; Forloni G; Tettamanti M; Frattura L; Tiraboschi P; Comelli M · Neurology · 1991
Randomized trial130 participantsflagBrain Health flagCognitive Support forscienceAcetyl L-Carnitine
- Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.
Jangid P; Malik P; Singh P; Sharma M; Gulia AK · Asian journal of psychiatry · 2013
Randomized trial70 participantsflagMood Support forscience5-HTP
- Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks.
Yoto A; Murao S; Motoki M; Yokoyama Y; Horie N; Takeshima K; Masuda K; Kim M; Yokogoshi H · Amino acids · 2012
Randomized trial63 participantsflagMood Support flagStress Relief forscienceGABA
- Ginkgo biloba for cognitive impairment and dementia.
Wieland LS; Ludeman E; Chi Y; Feinberg TM; Chen IH; Chen KH; Zhu Y; Wolverson E; Amri H · The Cochrane database of systematic reviews · 2026
Meta-analysis10,613 participants82 studies pooledflagBrain Health flagCognitive Support forscienceGinkgo
- Acetyl L-carnitine slows decline in younger patients with Alzheimer's disease: a reanalysis of a double-blind, placebo-controlled study using the trilinear approach.
Brooks JO; Yesavage JA; Carta A; Bravi D · International psychogeriatrics · 1998
Randomized trial334 participantsflagCognitive Support forscienceAcetyl L-Carnitine
- Alterations in gamma-aminobutyric acid and glutamate neurotransmission linked to intermittent theta-burst stimulation in depression: a sham-controlled study.
Steinholtz L; Bodén R; Wall A; Lubberink M; Fällmar D; Persson J · Translational psychiatry · 2025
Randomized trial42 participantsflagMood Support forscienceGABA
- Mental impairment in aging: selection of patients, methods of evaluation and therapeutic possibilities of acetyl-L-carnitine.
Passeri M; Iannuccelli M; Ciotti G; Bonati PA; Nolfe G; Cucinotta D · International journal of clinical pharmacology research · 1989
Randomized trial30 participantsflagBrain Health forscienceAcetyl L-Carnitine
- Effect of 5-Hydroxytryptophan on Fatigue in Quiescent Inflammatory Bowel Disease: A Randomized Controlled Trial.
Truyens M; Lobatón T; Ferrante M; Bossuyt P; Vermeire S; Pouillon L; Dewint P; Cremer A; Peeters H; Lambrecht G; Louis E; Rahier JF; Dewit O; Muls V; Holvoet T; Vandermeulen L; Peeters A; Gonzales GB; Bos S; Laukens D; De Vos M · Gastroenterology · 2022
Randomized trial166 participantsflagMood Support forscience5-HTP
- Pharmaco-electroencephalographic and clinical effects of the cholinergic substance--acetyl-L-carnitine--in patients with organic brain syndrome.
Herrmann WM; Dietrich B; Hiersemenzel R · International journal of clinical pharmacology research · 1990
Randomized trialflagBrain Health forscienceAcetyl L-Carnitine
- Acetyl-L-carnitine improves cognitive functions in severe hepatic encephalopathy: a randomized and controlled clinical trial.
Malaguarnera M; Vacante M; Motta M; Giordano M; Malaguarnera G; Bella R; Nunnari G; Rampello L; Pennisi G · Metabolic brain disease · 2012
Randomized trial61 participantsflagBrain Health flagCognitive Support forscienceAcetyl L-Carnitine
- Acetyl-L-carnitine in the treatment of mildly demented elderly patients.
Passeri M; Cucinotta D; Bonati PA; Iannuccelli M; Parnetti L; Senin U · International journal of clinical pharmacology research · 1990
Randomized trial60 participantsflagBrain Health flagMental Focus forscienceAcetyl L-Carnitine
- Ginkgo biloba extract EGb 761 is safe and effective in the treatment of mild dementia - a meta-analysis of patient subgroups in randomised controlled trials.
Riepe M; Hoerr R; Schlaefke S · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2025
Meta-analysis782 participants4 studies pooledflagBrain Health flagProductivity Boost forscienceGinkgo
- Ginkgo biloba extract EGb 761® improves cognition and overall condition after ischemic stroke: Results from a pilot randomized trial.
Cui M; You T; Zhao Y; Liu R; Guan Y; Liu J; Liu X; Wang X; Dong Q · Frontiers in pharmacology · 2023
Randomized trial201 participantsflagBrain Health flagProductivity Boost forscienceGinkgo
- Ginkgo biloba extract EGb 761® in dementia with neuropsychiatric features: a randomised, placebo-controlled trial to confirm the efficacy and safety of a daily dose of 240 mg.
Herrschaft H; Nacu A; Likhachev S; Sholomov I; Hoerr R; Schlaefke S · Journal of psychiatric research · 2012
Randomized trial410 participantsflagBrain Health forscienceGinkgo
- Huperzine a in the treatment of Alzheimer's disease and vascular dementia: a meta-analysis.
Xing SH; Zhu CX; Zhang R; An L · Evidence-based complementary and alternative medicine : eCAM · 2014
Meta-analysis825 participants10 studies pooledflagBrain Health flagCognitive Support forscienceHuperzine
- [Clinical efficacy and safety of huperzine Alpha in treatment of mild to moderate Alzheimer disease, a placebo-controlled, double-blind, randomized trial].
Zhang Z; Wang X; Chen Q; Shu L; Wang J; Shan G · Zhonghua yi xue za zhi · 2002
Randomized trial202 participantsflagBrain Health flagCognitive Support forscienceHuperzine
- Huperzine A associated with improved early postoperative cognitive function after neurosurgery under general anesthesia: a randomized clinical trial.
Zhang Z; Shen Y; Li J; Tang Y; Zhou P; Ying T; Mo R; Ru Z; Zhao G; Zhu J; Li S; Zhao H · International journal of surgery (London, England) · 2026
Randomized trial123 participantsflagBrain Health flagCognitive Support forscienceHuperzine
- Treatment with Huperzine A improves cognition in vascular dementia patients.
Xu ZQ; Liang XM; Juan-Wu; Zhang YF; Zhu CX; Jiang XJ · Cell biochemistry and biophysics · 2012
Randomized trial78 participantsflagBrain Health forscienceHuperzine
- Huperzine-A response to cognitive impairment and task switching deficits in patients with Alzheimer's disease.
Gul A; Bakht J; Mehmood F · Journal of the Chinese Medical Association : JCMA · 2019
Randomized trial100 participantsflagBrain Health forscienceHuperzine
- Does l-citrulline supplementation and watermelon intake reduce blood pressure in middle-aged and older adults? A systematic review and meta-analysis of randomized controlled trials.
Luo P; Chen J; Liu K; Zhang J · Clinical nutrition ESPEN · 2025
Meta-analysis415 participants15 studies pooledflagCardiovascular Support forscienceCitrulline
- Micronutrient Supplementation to Reduce Cardiovascular Risk.
An P; Wan S; Luo Y; Luo J; Zhang X; Zhou S; Xu T; He J; Mechanick JI; Wu WC; Ren F; Liu S · Journal of the American College of Cardiology · 2022
Meta-analysis883,627 participants884 studies pooledflagCardiovascular Support forscienceCitrulline
- l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans.
Bailey SJ; Blackwell JR; Lord T; Vanhatalo A; Winyard PG; Jones AM · Journal of applied physiology (Bethesda, Md. : 1985) · 2016
Randomized trial10 participantsflagCardiovascular Support forscienceCitrulline
- Effects of L-Citrulline Supplementation on Endothelial Function and Blood Pressure in Hypertensive Postmenopausal Women.
Maharaj A; Fischer SM; Dillon KN; Kang Y; Martinez MA; Figueroa A · Nutrients · 2022
Randomized trial25 participantsflagCardiovascular Support forscienceCitrulline
- Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged men.
Ochiai M; Hayashi T; Morita M; Ina K; Maeda M; Watanabe F; Morishita K · International journal of cardiology · 2012
Randomized trial15 participantsflagCardiovascular Support forscienceCitrulline
- The current state of niacin in cardiovascular disease prevention: a systematic review and meta-regression.
Lavigne PM; Karas RH · Journal of the American College of Cardiology · 2013
Meta-analysis9,959 participants11 studies pooledflagCardiovascular Support forscienceNiacin
- Effects of niacin on apo A1 and B levels: a systematic review and meta-analysis of randomised controlled trials.
Saboori S; Yousefi Rad E; Tammam J; Thondre PS; Coe S · The British journal of nutrition · 2024
Meta-analysis12 studies pooledflagCardiovascular Support forscienceNiacin
- Effect of lipid-lowering therapies on lipoprotein(a) levels: a comprehensive meta-analysis of randomized controlled trials.
Xie S; Galimberti F; Olmastroni E; Carugo S; Catapano AL; Casula M; META-LIPID Group · Atherosclerosis · 2025
Meta-analysis145,314 participants147 studies pooledflagCardiovascular Support forscienceNiacin
- Extended-release niacin vs gemfibrozil for the treatment of low levels of high-density lipoprotein cholesterol. Niaspan-Gemfibrozil Study Group.
Guyton JR; Blazing MA; Hagar J; Kashyap ML; Knopp RH; McKenney JM; Nash DT; Nash SD · Archives of internal medicine · 2000
Randomized trial173 participantsflagCardiovascular Support forscienceNiacin
- Equivalent efficacy of a time-release form of niacin (Niaspan) given once-a-night versus plain niacin in the management of hyperlipidemia.
Knopp RH; Alagona P; Davidson M; Goldberg AC; Kafonek SD; Kashyap M; Sprecher D; Superko HR; Jenkins S; Marcovina S · Metabolism: clinical and experimental · 1998
Randomized trial223 participantsflagCardiovascular Support forscienceNiacin
- A double-blind, parallel, multicenter comparison of L-acetylcarnitine with placebo on the attention deficit hyperactivity disorder in fragile X syndrome boys.
Torrioli MG; Vernacotola S; Peruzzi L; Tabolacci E; Mila M; Militerni R; Musumeci S; Ramos FJ; Frontera M; Sorge G; Marzullo E; Romeo G; Vallee L; Veneselli E; Cocchi E; Garbarino E; Moscato U; Chiurazzi P; D'Iddio S; Calvani M; Neri G · American journal of medical genetics. Part A · 2008
Randomized trial63 participantsflagCognitive Support forscienceAcetyl L-Carnitine
- Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue.
Malaguarnera M; Gargante MP; Cristaldi E; Colonna V; Messano M; Koverech A; Neri S; Vacante M; Cammalleri L; Motta M · Archives of gerontology and geriatrics · 2008
Randomized trial96 participantsflagCognitive Support forscienceAcetyl L-Carnitine
- Senile dementia: treatment with deanol.
Ferris SH; Sathananthan G; Gershon S; Clark C · Journal of the American Geriatrics Society · 1977
Single-arm trial14 participantsflagCognitive Support forscienceDeanol
- Effects of dimethylaminoethanol pyroglutamate (DMAE p-Glu) against memory deficits induced by scopolamine: evidence from preclinical and clinical studies.
Blin O; Audebert C; Pitel S; Kaladjian A; Casse-Perrot C; Zaim M; Micallef J; Tisne-Versailles J; Sokoloff P; Chopin P; Marien M · Psychopharmacology · 2010
Randomized trial24 participantsflagCognitive Support forscienceDeanol
- Efficacy of ginkgo diterpene lactone meglumine on cognitive function in patients with acute ischemic stroke: a predefined exploratory analysis of a multicenter, double-blind, randomized controlled trial.
Tian X; Xu Q; Xia X; Zhang Y; Meng X; Wang A · Journal of neurology · 2024
Randomized trial3,163 participantsflagCognitive Support forscienceGinkgo
- A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group.
Le Bars PL; Katz MM; Berman N; Itil TM; Freedman AM; Schatzberg AF · JAMA · 1997
Randomized trial309 participantsflagCognitive Support flagProductivity Boost forscienceGinkgo
- Alleviating neuropsychiatric symptoms in dementia: the effects of Ginkgo biloba extract EGb 761. Findings from a randomized controlled trial.
Bachinskaya N; Hoerr R; Ihl R · Neuropsychiatric disease and treatment · 2011
Randomized trial410 participantsflagCognitive Support forscienceGinkgo
- Efficacy and safety of a once-daily formulation of Ginkgo biloba extract EGb 761 in dementia with neuropsychiatric features: a randomized controlled trial.
Ihl R; Bachinskaya N; Korczyn AD; Vakhapova V; Tribanek M; Hoerr R; Napryeyenko O; GOTADAY Study Group · International journal of geriatric psychiatry · 2013
Randomized trial410 participantsflagCognitive Support forscienceGinkgo
- Adjunctive huperzine A for cognitive deficits in schizophrenia: a systematic review and meta-analysis.
Zheng W; Xiang YQ; Li XB; Ungvari GS; Chiu HF; Sun F; D'Arcy C; Meng X; Xiang YT · Human psychopharmacology · 2017
Meta-analysis1,117 participants12 studies pooledflagCognitive Support forscienceHuperzine
- [Drug evaluation of huperzine A in the treatment of senile memory disorders].
Zhang RW; Tang XC; Han YY; Sang GW; Zhang YD; Ma YX; Zhang CL; Yang RM · Zhongguo yao li xue bao = Acta pharmacologica Sinica · 1992
Randomized trial56 participantsflagCognitive Support forscienceHuperzine
- Causes of hair loss and the developments in hair rejuvenation.
Rushton DH; Norris MJ; Dover R; Busuttil N · International journal of cosmetic science · 2010
Narrative reviewflagHair Health forscienceLysine
- Acetyl-L-Carnitine Supplementation During HCV Therapy With Pegylated Interferon-α 2b Plus Ribavirin: Effect on Work Performance; A Randomized Clinical Trial.
Malaguarnera G; Pennisi M; Gagliano C; Vacante M; Malaguarnera M; Salomone S; Drago F; Bertino G; Caraci F; Nunnari G; Malaguarnera M · Hepatitis monthly · 2014
Randomized trial62 participantsflagMental Focus flagProductivity Boost forscienceAcetyl L-Carnitine
- [Psycho-functional changes in attention and learning under the action of L-acetylcarnitine in 17 young subjects. A pilot study of its use in mental deterioration].
Lino A; Boccia MM; Rusconi AC; Bellomonte L; Cocuroccia B · La Clinica terapeutica · 1992
Non-randomized trial17 participantsflagMental Focus forscienceAcetyl L-Carnitine
- Acetyl-L-carnitine (ALC) in attention-deficit/hyperactivity disorder: a multi-site, placebo-controlled pilot trial.
Arnold LE; Amato A; Bozzolo H; Hollway J; Cook A; Ramadan Y; Crowl L; Zhang D; Thompson S; Testa G; Kliewer V; Wigal T; McBurnett K; Manos M · Journal of child and adolescent psychopharmacology · 2008
Randomized trial112 participantsflagMental Focus forscienceAcetyl L-Carnitine
- Acetyl-L-carnitine for patients with hepatic encephalopathy.
Martí-Carvajal AJ; Gluud C; Arevalo-Rodriguez I; Martí-Amarista CE · The Cochrane database of systematic reviews · 2019
Meta-analysis398 participants5 studies pooledflagMental Focus forscienceAcetyl L-Carnitine
- Ginkgo biloba Extract EGb 761 in the Treatment of Patients with Mild Neurocognitive Impairment: A Systematic Review.
Hort J; Duning T; Hoerr R · Neuropsychiatric disease and treatment · 2023
Systematic review946 participants9 studies pooledflagMental Focus forscienceGinkgo
- Proof of efficacy of the Ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia.
Kanowski S; Herrmann WM; Stephan K; Wierich W; Hörr R · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
Randomized trial216 participantsflagMental Focus forscienceGinkgo
- Proof of efficacy of the ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia.
Kanowski S; Herrmann WM; Stephan K; Wierich W; Hörr R · Pharmacopsychiatry · 1996
Randomized trial216 participantsflagMental Focus forscienceGinkgo
- Ginkgo biloba extract improved cognitive and neurological functions of acute ischaemic stroke: a randomised controlled trial.
Li S; Zhang X; Fang Q; Zhou J; Zhang M; Wang H; Chen Y; Xu B; Wu Y; Qian L; Xu Y · Stroke and vascular neurology · 2021
Randomized trial348 participantsflagMental Focus forscienceGinkgo
- Ginkgo biloba in the Aging Process: A Narrative Review.
Barbalho SM; Direito R; Laurindo LF; Marton LT; Guiguer EL; Goulart RA; Tofano RJ; Carvalho ACA; Flato UAP; Capelluppi Tofano VA; Detregiachi CRP; Bueno PCS; Girio RSJ; Araújo AC · Antioxidants (Basel, Switzerland) · 2024
Narrative review14 studies pooledflagMental Focus forscienceGinkgo
- Low Bioavailability and High TMAO Production: Novel Insights Into Acetylcarnitine and Carnitine Metabolism.
Krims-Davis K; Ozola M; Razzivina V; Gukalova B; Konrade I; Dambrova M; Liepinsh E · Molecular nutrition & food research · 2025
Randomized trialflagMetabolism Boost forscienceAcetyl L-Carnitine
- Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes.
Anderson RA; Cheng N; Bryden NA; Polansky MM; Cheng N; Chi J; Feng J · Diabetes · 1997
Randomized trial180 participantsflagMetabolism Boost forscienceChromium
- Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Jamilian M; Asemi Z · Annals of nutrition & metabolism · 2016
Randomized trial64 participantsflagMetabolism Boost forscienceChromium
- A Comprehensive insight into the effect of chromium supplementation on oxidative stress indices in diabetes mellitus: A systematic review.
Kooshki F; Tutunchi H; Vajdi M; Karimi A; Niazkar HR; Shoorei H; Pourghassem Gargari B · Clinical and experimental pharmacology & physiology · 2024
Systematic review33 studies pooledflagMetabolism Boost forscienceChromium
- Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
Meta-analysis2,362 participants41 studies pooledflagMetabolism Boost forscienceChromium
- [Chromium supplementation in patients with type 2 diabetes and high risk of type 2 diabetes: a meta-analysis of randomized controlled trials].
San Mauro-Martin I; Ruiz-León AM; Camina-Martín MA; Garicano-Vilar E; Collado-Yurrita L; Mateo-Silleras Bd; Redondo Del Río Mde P · Nutricion hospitalaria · 2017
Meta-analysis13 studies pooledflagMetabolism Boost forscienceChromium
- The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial.
Li S; Sutanto CN; Xia X; Kim JE · Nutrients · 2025
Randomized trial30 participantsflagMood Support forscience5-HTP
- Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis.
Javelle F; Lampit A; Bloch W; Häussermann P; Johnson SL; Zimmer P · Nutrition reviews · 2020
Meta-analysis13 studies pooledflagMood Support forscience5-HTP
- Tryptophan and 5-hydroxytryptophan for depression.
Shaw K; Turner J; Del Mar C · The Cochrane database of systematic reviews · 2002
Systematic review64 participants2 studies pooledflagMood Support forscience5-HTP
- 5-Hydroxytryptophan (5-HTP) and a MAOI (nialamide) in the treatment of depressions. A double-blind controlled study.
Aliño JJ; Gutierrez JL; Iglesias ML · International pharmacopsychiatry · 1976
Non-randomized trial30 participantsflagMood Support forscience5-HTP
- Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression.
Deligiannidis KM; Kroll-Desrosiers AR; Mo S; Nguyen HP; Svenson A; Jaitly N; Hall JE; Barton BA; Rothschild AJ; Shaffer SA · Psychoneuroendocrinology · 2017
Cohort study56 participantsflagMood Support forscienceGABA
- The role of neurotransmitters in mediating the relationship between brain alterations and depressive symptoms in patients with inflammatory bowel disease.
Wang J; Liu G; Xu K; Ai K; Huang W; Zhang J · Human brain mapping · 2023
Case-control study69 participantsflagMood Support forscienceGABA
- Occipital gamma-aminobutyric acid and glutamate-glutamine alterations in major depressive disorder: An mrs study and meta-analysis.
Truong V; Cheng PZ; Lee HC; Lane TJ; Hsu TY; Duncan NW · Psychiatry research. Neuroimaging · 2021
Observational studyflagMood Support forscienceGABA
- Systematic review of gamma-aminobutyric-acid inhibitory deficits across the reproductive life cycle.
Vigod SN; Strasburg K; Daskalakis ZJ; Blumberger DM · Archives of women's mental health · 2014
Systematic review11 studies pooledflagMood Support forscienceGABA
- [Ginkgo biloba extract EGb 761 in the treatment of dementia: evidence of efficacy and tolerability].
Kasper S; Schubert H · Fortschritte der Neurologie-Psychiatrie · 2009
Meta-analysis10 studies pooledflagProductivity Boost forscienceGinkgo
- Dietary Flavonoids and Human Cognition: A Meta-Analysis.
Cheng N; Bell L; Lamport DJ; Williams CM · Molecular nutrition & food research · 2022
Meta-analysis5,519 participants80 studies pooledflagProductivity Boost forscienceGinkgo
- Limited cognitive benefits in Stage +2 postmenopausal women after 6 weeks of treatment with Ginkgo biloba.
Elsabagh S; Hartley DE; File SE · Journal of psychopharmacology (Oxford, England) · 2005
Randomized trial87 participantsflagProductivity Boost forscienceGinkgo
- Efficacy and safety of Ginkgo biloba extract EGb 761 in mild cognitive impairment with neuropsychiatric symptoms: a randomized, placebo-controlled, double-blind, multi-center trial.
Gavrilova SI; Preuss UW; Wong JW; Hoerr R; Kaschel R; Bachinskaya N; GIMCIPlus Study Group · International journal of geriatric psychiatry · 2015
Randomized trial160 participantsflagProductivity Boost forscienceGinkgo
- Modulation of cognitive performance following single doses of 120 mg Ginkgo biloba extract administered to healthy young volunteers.
Kennedy DO; Jackson PA; Haskell CF; Scholey AB · Human psychopharmacology · 2008
Randomized trial78 participantsflagProductivity Boost forscienceGinkgo
- Effect of Huperzine A on Cognitive Function and Perception of Effort during Exercise: A Randomized Double-Blind Crossover Trial.
Wessinger CM; Inman CL; Weinstock J; Weiss EP · International journal of exercise science · 2025
Randomized trial15 participantsflagProductivity Boost forscienceHuperzine
- The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial.
Sutanto CN; Xia X; Heng CW; Tan YS; Lee DPS; Fam J; Kim JE · Clinical nutrition (Edinburgh, Scotland) · 2024
Randomized trial30 participantsflagSleep Support forscience5-HTP
- Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial.
Byun JI; Shin YY; Chung SE; Shin WC · Journal of clinical neurology (Seoul, Korea) · 2020
Randomized trial40 participantsflagSleep Support forscienceGABA
- Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Problems.
Imafuku F; Yamamoto K; Tanaka E; Aoki R; Nishino S · Nutrients · 2023
Randomized trial160 participantsflagSleep Support forscienceGABA
- Reduced γ-aminobutyric acid in occipital and anterior cingulate cortices in primary insomnia: a link to major depressive disorder?
Plante DT; Jensen JE; Schoerning L; Winkelman JW · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012
Case-control study40 participantsflagSleep Support forscienceGABA
- GABA Supplementation, Increased Heart-Rate Variability, Emotional Response, Sleep Efficiency and Reduced Depression in Sedentary Overweight Women Undergoing Physical Exercise: Placebo-Controlled, Randomized Clinical Trial.
Guimarães AP; Seidel H; Pires LVM; Trindade CO; Baleeiro RDS; Souza PM; Silva FGDE; Coelho DB; Becker LK; Oliveira EC · Journal of dietary supplements · 2024
Randomized trial30 participantsflagSleep Support flagStress Relief forscienceGABA
- The effect of glycine administration on the characteristics of physiological systems in human adults: A systematic review.
Soh J; Raventhiran S; Lee JH; Lim ZX; Goh J; Kennedy BK; Maier AB · GeroScience · 2024
Systematic reviewflagSleep Support forscienceGlycine
- New therapeutic strategy for amino acid medicine: glycine improves the quality of sleep.
Bannai M; Kawai N · Journal of pharmacological sciences · 2012
Narrative reviewflagSleep Support forscienceGlycine
- The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers.
Bannai M; Kawai N; Ono K; Nakahara K; Murakami N · Frontiers in neurology · 2012
Clinical trial7 participantsflagSleep Support forscienceGlycine
- Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo.
Kahn RS; Westenberg HG; Verhoeven WM; Gispen-de Wied CC; Kamerbeek WD · International clinical psychopharmacology · 1987
Randomized trial45 participantsflagStress Relief forscience5-HTP
- Acute L-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients.
Schruers K; van Diest R; Overbeek T; Griez E · Psychiatry research · 2003
Randomized trial48 participantsflagStress Relief forscience5-HTP
- Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa.
Smarius LJ; Jacobs GE; Hoeberechts-Lefrandt DH; de Kam ML; van der Post JP; de Rijk R; van Pelt J; Schoemaker RC; Zitman FG; van Gerven JM; Gijsman HJ · Journal of psychopharmacology (Oxford, England) · 2008
Randomized trialflagStress Relief forscience5-HTP
- Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron.
Jacobs GE; Kamerling IM; de Kam ML; Derijk RH; van Pelt J; Zitman FG; van Gerven JM · Journal of psychopharmacology (Oxford, England) · 2010
Randomized trialflagStress Relief forscience5-HTP
- An open-label trial of L-5-hydroxytryptophan in subjects with romantic stress.
Emanuele E; Bertona M; Minoretti P; Geroldi D · Neuro endocrinology letters · 2011
Single-arm trial15 participantsflagStress Relief forscience5-HTP
- Relieving occupational fatigue by consumption of a beverage containing γ-amino butyric acid.
Kanehira T; Nakamura Y; Nakamura K; Horie K; Horie N; Furugori K; Sauchi Y; Yokogoshi H · Journal of nutritional science and vitaminology · 2011
Clinical trial30 participantsflagStress Relief forscienceGABA
- Cortical gamma-aminobutyric acid and glutamate in posttraumatic stress disorder and their relationships to self-reported sleep quality.
Meyerhoff DJ; Mon A; Metzler T; Neylan TC · Sleep · 2014
Case-control study45 participantsflagStress Relief forscienceGABA
- Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK · Journal of anaesthesiology, clinical pharmacology · 2025
Randomized trial168 participantsflagStress Relief forscienceGABA
- Oral supplementation with glycine reduces oxidative stress in patients with metabolic syndrome, improving their systolic blood pressure.
Díaz-Flores M; Cruz M; Duran-Reyes G; Munguia-Miranda C; Loza-Rodríguez H; Pulido-Casas E; Torres-Ramírez N; Gaja-Rodriguez O; Kumate J; Baiza-Gutman LA; Hernández-Saavedra D · Canadian journal of physiology and pharmacology · 2014
Randomized trial60 participantsflagStress Relief forscienceGlycine