Product Image

L-Glutathione (Reduced) 500 mg

California Gold Nutrition
4.6
★ ★ ★ ★ ★
(17160 ratings)
Gluthathione 500 mg
Product Image
Score84
A substantial, clearly labeled reduced-glutathione serving gives this focused capsule strong practical value. Standard oral delivery is the main limitation.
How scoring works
Quantity:30 Capsule(s) • (30 servings)
Goals:
Skin Health

Score 84

A substantial, clearly labeled reduced-glutathione serving gives this focused capsule strong practical value. Standard oral delivery is the main limitation.
How scoring works

Also available as

1 option
120 servings Gluthathione 500 mg • 120 Capsule(s) • 120 servings $42.34 ($0.35 per serving)
$12.05($0.40 per serving)
iHerb
$ 12.05
Amazon
$ 23.96
Report prices

Analysis

A clearly identified reduced form and 500 mg serving give the formula strong dose transparency. The single-active design avoids low-dose supporting ingredients that would distract from its main purpose.

Reduced glutathione is a more informative label description than unspecified L-glutathione. The capsule does not identify liposomal or acetylated delivery, however, so digestive stability and absorption may vary.

The formula suits adults seeking direct antioxidant support and may be relevant to skin tone or oxidative stress. It remains narrower than a complete skin product because it does not provide collagen, barrier lipids, or hydration support.

Who is it for
  • Adults seeking high-dose reduced glutathione
  • Users who prefer single-active capsules
  • Skin-focused users who already cover structural support elsewhere
Best for
  • Focused antioxidant supplementation
  • Clear reduced-form labeling
  • Users prioritizing dose and serving efficiency

Pros

  • Clearly identifies reduced glutathione
  • Provides 500 mg per serving
  • Single-active formula
  • Strong serving value

Cons

  • No verified liposomal or acetylated delivery
  • No branded purity source is named
  • Absorption may vary with standard oral delivery
  • Does not address collagen or skin hydration

Nutrient quality

84 Highest impact

Reduced glutathione is the preferred redox form, though standard oral delivery lacks enhanced protection. The substantial reduced glutathione amount provides meaningful dose depth.

.

Ingredient transparency

83 Highest impact

Every listed active ingredient has a specific amount. Usage and inactive-ingredient details remain incomplete.

.

Customer satisfaction

71 High impact

The average rating is positive but not exceptional. The very large feedback pool makes the average highly dependable.

.

Value for money

96 Highest impact

The substantial reduced dose strongly supports the modest price. Serving cost is excellent for the disclosed dose.

.
Report analysis

Goals

Skin Health
Skin Health
Impact
High effect
C- Goal FitB Strength of SupportD CoverageA- Formula Quality
Gluthathione · 500 mg

Reduced glutathione supplies a direct antioxidant that may modestly support skin tone and oxidative defense. The single ingredient does not address collagen structure, barrier lipids, or hydration.

The amount is useful and fully disclosed, but no liposomal or other enhanced delivery is identified. Oral absorption and visible skin responses can vary substantially.

Study evidence
Gluthathione Supportive 13 studies

Ingredients

IngredientAmount per serving
L-Glutathione
500 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Gluthathione · 500 mg OverallScore77
D- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Reduced L-glutathione supplies a full 500 mg dose suited to meaningful antioxidant support. The standard reduced form is less protected from digestion than liposomal or acetylated alternatives, and no branded purity source is disclosed. A low serving cost makes the formula particularly efficient for its dose.

View ingredientView products
Loading alternative details
84 Performance

L-Glutathione (Reduced) 500 mg

California Gold Nutrition
<p>Its label clearly provides 500 mg of L-Glutathione, Reduced, making it a more clearly defined glutathione option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
76 Performance

Reduced Glutathione 250 mg

Source Naturals
<p>Its label clearly provides 250 mg of L-Glutathione, Reduced, making it a more clearly defined glutathione option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
74 Performance

Optimal Liposomal Glutathione Plus

Seeking Health
<p>Its label clearly provides 350 mg of L-Glutathione, making it a more clearly defined glutathione option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
79 Budget

Glutathione 500 mg

Nutricost
<p>Its label clearly provides 500 mg of L-Glutathione, preserving relevant glutathione coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
76 Budget

L-Glutathione 500 mg

AN Amazing Nutrition Amazing Formulas
<p>Its label clearly provides 500 mg of L-Glutathione, preserving relevant glutathione coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
73 Budget

Chem-Defense Orange Flavored

Source Naturals
<p>Its label clearly provides 50 mg of L-Glutathione, preserving relevant glutathione coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
72 Value

L-Glutathione 100 mg

Bluebonnet
<p>Its label clearly provides 100 mg of L-Glutathione, Reduced, keeping the formula relevant to glutathione. Compared with the original, the somewhat higher serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
79 Value

Mega-Liposomal Glutathione+ 750 mg Organic Fruit Flavor

Aurora NutraScience
<p>Its label clearly provides 750 mg of L-Glutathione, keeping the formula relevant to glutathione. Compared with the original, the somewhat higher serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
75 Value

Reduced Glutathione Complex 50 mg Orange Flavored

Source Naturals
<p>Its label clearly provides 50 mg of L-Glutathione, keeping the formula relevant to glutathione. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The effects of the oral supplementation of L-Cystine associated with reduced L-Glutathione-GSH on human skin pigmentation: a randomized, double-blinded, benchmark- and placebo-controlled clinical trial.
    Duperray J; Sergheraert R; Chalothorn K; Tachalerdmanee P; Perin F · Journal of cosmetic dermatology · 2022
    Randomized trial124 participantsSkin Health forGluthathione
  2. Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women.
    Watanabe F; Hashizume E; Chan GP; Kamimura A · Clinical, cosmetic and investigational dermatology · 2014
    Randomized trial30 participantsSkin Health forGluthathione
  3. Systematic Review of the Efficacy and Safety of Topical Glutathione in Dermatology.
    Khanna R; Rambhia P; Chapas A · The Journal of clinical and aesthetic dermatology · 2025
    Systematic review5 studies pooledSkin Health forGluthathione
  4. Effects of antioxidants on glutathione levels and clinical recovery from the malnutrition syndrome kwashiorkor--a pilot study.
    Becker K; Pons-Kühnemann J; Fechner A; Funk M; Gromer S; Gross HJ; Grünert A; Schirmer RH · Redox report : communications in free radical research · 2006
    Randomized trialSkin Health forGluthathione
  5. Glutathione and its antiaging and antimelanogenic effects.
    Weschawalit S; Thongthip S; Phutrakool P; Asawanonda P · Clinical, cosmetic and investigational dermatology · 2020
    Randomized trial57 participantsSkin Health forGluthathione