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Adrenal Support

Vital Nutrients
4.7
★ ★ ★ ★ ★
(233 ratings)
Eleuthero 200 mg
Vitamin B5 100 mg
Cordyceps 100 mg
Ashwagandha 200 mg
Product Image
Score68
A concentrated adaptogen and glandular formula with useful B5 and eleuthero. Animal-derived tissues, low cordyceps, and several interaction concerns limit broad suitability.
How scoring works
Quantity:60 Capsule(s) • (30 servings)
Goals:
Cognitive Support

Score 68

A concentrated adaptogen and glandular formula with useful B5 and eleuthero. Animal-derived tissues, low cordyceps, and several interaction concerns limit broad suitability.
How scoring works

Also available as

1 option
120 servings Ashwagandha 200 mg, B5 100 mg +2 more • 120 Capsule(s) • 60 servings $57.99 ($0.96 per serving)
$31.99($1.06 per serving)
Vitacost
$ 31.99
iHerb
$ 31.99
Pure Formulas
$ 31.99
Vitacost
$ 31.99
Report prices

Analysis

Eleuthero and ashwagandha provide the main adaptogen-style support, while calcium pantothenate contributes substantial B5. Cordyceps is present at a small amount relative to focused products.

Bovine whole adrenal and cortex make the formula unsuitable for vegetarians and add a specialized glandular component. The combination is only moderately aligned with cognitive support and should not be treated as a direct nootropic.

The two-capsule serving is manageable, but the 30-serving supply is relatively costly. The complex caution profile matters more than the strong aggregate satisfaction data.

Who is it for
  • Adults specifically seeking an adaptogen-glandular blend
  • Non-vegetarian users
  • People willing to review medication and thyroid considerations
Best for
  • Combined eleuthero and ashwagandha intake
  • Stress-oriented nutritional support
  • Users seeking bovine glandular ingredients

Pros

  • Substantial vitamin B5 amount
  • Useful eleuthero amount
  • Includes ashwagandha
  • All active weights are listed

Cons

  • Contains bovine adrenal tissues
  • Cordyceps amount is low
  • Only moderate cognitive-goal fit
  • High serving cost

Warnings

  • Ashwagandha warrants caution during pregnancy and with thyroid or liver concerns
  • Eleuthero may affect blood pressure or stimulant medicines
  • Bovine adrenal ingredients are unsuitable for vegetarians and may conflict with personal dietary restrictions

Nutrient quality

75 High impact

Eleuthero and pantothenic acid provide the strongest quality and dose support. Modest adaptogen doses and incompletely characterized bovine glandular ingredients limit confidence.

Ingredient transparency

74 High impact

All listed actives have specific amounts without a proprietary blend. Extract markers, glandular sourcing details, directions, and non-active capsule ingredients remain incomplete.

Customer satisfaction

68 High impact

The supplied satisfaction metric is strong and response volume is substantial. Specific firsthand feedback was not supplied, so recurring complaints and purpose alignment remain uncertain.

Value for money

53 Moderate impact

A coherent adaptogen-and-glandular formula partly supports the cost. High serving cost and incomplete standardization weaken category value.

Report analysis

Goals

Cognitive Support
Cognitive Support
Impact
High effect
C Goal FitB- Strength of SupportC CoverageB+ Formula Quality
Ashwagandha · 200 mg

Adrenal Support combines 200 mg eleuthero with 200 mg ashwagandha and may support stress-related fatigue, but it does not directly target memory or cholinergic signaling.

Customer feedback averages 4.69 from 222 reviews; The multi-ingredient label and possible sedative, stimulant, or medication interactions deserve review.

Study evidence
Ashwagandha Supportive 17 studies
Eleuthero No effect 1 study

Ingredients

IngredientAmount per serving
Pantothenic Acid (Calcium Pantothenate)
 100 mg
Bovine Whole Adrenal
300 mg
Bovine Adrenal Cortex
150 mg
Eleuthero root extract
200 mg
Ashwagandha root extract
200 mg
Cordyceps sinensis mycelium extract
100 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
Eleuthero · 200 mg OverallScore76
A+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

The 200 mg Eleuthero root extract is standardized to 0.8% eleutherosides and fully disclosed. Active quality is strong, but the $1.06 serving price reduces value despite the dose clearing the collection's minimum threshold.

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Vitamin B5 (Calcium Pantothenate) · 100 mg OverallScore72
A Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

Vital Nutrients Adrenal Support provides 100 mg of calcium pantothenate, uses a short excipient list, and has 222 reviews averaging 4.69. Independent label testing adds a useful quality signal, but the $1.06 serving cost works out to $5.30 per 500 mg of B5.

View ingredientView products
Cordyceps · 100 mg OverallScore52
C Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyF Value

Adrenal Support supplies 100 mg Cordyceps sinensis mycelium extract and has a 4.69 average from 222 reviews. Vital Nutrients identifies independent testing and an adenosine-standardized extract, though the cordyceps dose remains well below the collection median.

View ingredientView products
Loading alternative details
81 Performance

Adrenal Serenity

Natural Factors Stress-Relax
<p>Sensoril ashwagandha, eleuthero, lavender, and rhodiola provide a concise, well-characterized stress formula without bovine glandulars. Some extract and inactive-ingredient details are missing, but the focused design and strong cognitive alignment improve usability.</p>
81 Performance

AdrenaSense

Natural Factors WS WomenSense
<p>Marker-identified rhodiola, eleuthero, schisandra, and ashwagandha create clear stress-resilience support without animal-derived tissues. The formula omits cordyceps and pantothenic acid but offers stronger label clarity and a more focused adaptogen profile.</p>
73 Performance

HPA Adapt

Integrative Therapeutics
<p>Substantial Sensoril, rhodiola, eleuthero, holy basil, and branded maca create deeper stress and stamina support than the original. Missing marker percentages and high serving cost limit value, but the plant-only formula avoids bovine glandulars.</p>
69 Budget

Adrenal Support

Vital Nutrients
<p>The identical eleuthero, ashwagandha, cordyceps, pantothenic acid, and bovine adrenal formula comes in a larger supply at lower serving cost. Ingredient strengths and limitations are unchanged, including modest adaptogen characterization and animal-derived glandulars.</p>
79 Budget

Dual Ginseng Plus

Swanson Superior Herbs
<p>Standardized ginseng and eleuthero provide a much lower-cost adaptogen base without bovine glandular tissues. Ashwagandha is unstandardized and cordyceps is absent, but the core stimulant-free energy formula is simpler.</p>
67 Budget

Adrenal Optimizer

Jarrow Formulas
<p>Ashwagandha, rhodiola, eleuthero, schisandra, and supportive herbs create a lower-cost plant-only stress and energy blend. Standardization is weak, doses are modest, and licorice still raises suitability concerns.</p>
72 Value

CalmEssence

Pure Essence
<p>Ashwagandha and theanine anchor a coherent calming blend with supporting adaptogens and no glandular ingredients. Most extracts lack marker standardization and serving cost is slightly higher, so value depends on preferring a plant-only calming profile.</p>
68 Value

Stress Remedy

Pure Synergy
<p>A high ashwagandha amount leads a broad plant-only stress blend with useful calming support. Many secondary extracts are lightly dosed or unstandardized and serving cost is high, limiting the economic advantage.</p>
68 Value

Adrenotone

Designs for Health
<p>A broad adaptogen and active B-vitamin blend supports stress-related energy and focus without bovine tissues. Several botanicals are modest or incompletely standardized, and the relatively high serving cost prevents a clear value win.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
    Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
    Randomized trial40 participantsCognitive Support forAshwagandha
  2. Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
    Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
    Randomized trial59 participantsCognitive Support forAshwagandha
  3. A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.
    Majeed M; Nagabhushanam K; Mundkur L · Medicine · 2023
    Randomized trial54 participantsCognitive Support forAshwagandha
  4. Efficacy and safety of ashwagandha root extract in children and adolescents with mild attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled trial.
    Naik S; Muralidhar G; Rao BS; Agarwal S; Jain M · Journal of medicine and life · 2026
    Randomized trial58 participantsCognitive Support forAshwagandha
  5. Efficacy of Withania somnifera supplementation on adult's cognition and mood.
    Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
    Randomized trial60 participantsCognitive Support forAshwagandha
  6. No benefit adding eleutherococcus senticosus to stress management training in stress-related fatigue/weakness, impaired work or concentration, a randomized controlled study.
    Schaffler K; Wolf OT; Burkart M · Pharmacopsychiatry · 2014
    Randomized trial144 participantsCognitive Support forEleuthero