Product Image

a Drenal

RLC Labs
4.8
★ ★ ★ ★ ★
(46 ratings)
Theanine 100 mg
Rhodiola
Eleuthero 100 mg
Ashwagandha 150 mg
Astragalus 100 mg
Ginger
Cordyceps 400 mg
Product Image
Score59
A crowded adaptogen and bovine adrenal formula with modest botanical doses and weak value.
How scoring works
Quantity:120 Capsule(s) • (30 servings)
Goals:
Mood Support
Productivity Boost
Stress Relief
Mental Focus
Energy

Score 59

A crowded adaptogen and bovine adrenal formula with modest botanical doses and weak value.
How scoring works
$55.99($1.86 per serving)
Pure Formulas
$ 55.99
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Analysis

Cordyceps leads the formula at 400 mg, followed by 250 mg organic bovine adrenal tissue. Ashwagandha, rhodiola, eleuthero, ginseng, astragalus, theanine, and ginger broaden stress and energy support.

Most individual botanicals provide 50 to 150 mg, which is modest for such a crowded formula. Pantothenic acid is high at 250 mg, while adrenal tissue adds an animal-derived component with limited compositional detail.

The four-capsule serving may appeal to users wanting a broad adaptogen blend. It is poorly suited to vegans and offers no clear reason to expect direct weight-loss or sleep benefits.

Who is it for
  • Adults specifically seeking an adaptogen and glandular blend
  • People comfortable with bovine ingredients
Best for
  • Broad daytime stress support
  • Cordyceps-centered routines

Pros

  • Provides 400 mg cordyceps
  • Includes several standardized adaptogens
  • Adds 100 mg L-theanine

Cons

  • Contains bovine adrenal tissue
  • Most botanicals are modestly dosed
  • Requires four capsules

Warnings

  • Bovine adrenal tissue makes the product unsuitable for vegans and users avoiding glandular ingredients.
  • Ashwagandha may not suit people with hyperthyroidism or those using thyroid medicine without guidance.
  • Ginseng, ginger, and rhodiola can interact with anticoagulant, stimulant, or psychiatric medicines.

Nutrient quality

61 Moderate impact

Several adaptogens name active markers, but marker percentages and the cordyceps extract strength are absent. Theanine is practical, while most adaptogens sit at modest blend-level amounts and cordyceps is raw powder.

Ingredient transparency

76 High impact

All listed nutrients, glandular material, and botanicals have individual amounts. Excipients and daily directions are absent from the supplied data, which leaves some label details uncertain.

Customer satisfaction

64 Moderate impact

The aggregate satisfaction average is strong, though no detailed feedback is supplied. The limited volume supports only moderate confidence in the aggregate signal.

Value for money

30 Situational impact

Broad adaptogen coverage is offset by modest doses and uncertain glandular value. The serving cost is high relative to the depth of the best-characterized actives.

Report analysis

Goals

Mood Support
Mood Support
Impact
High effect
A- Goal FitC+ Strength of SupportB+ CoverageA- Formula Quality
Ashwagandha · 150 mg

Ashwagandha, Rhodiola, and L-theanine form a direct stress-and-mood support combination. L-theanine at 100 mg is well aligned, while the 150 mg ashwagandha and 100 mg Rhodiola amounts are comparatively modest.

The formula addresses stress response, calm attention, and adaptogenic resilience through distinct ingredients. Theanine complements the two adaptogens without an obvious stimulating conflict.

Study evidence
Ashwagandha Supportive 29 studies
Rhodiola Supportive 15 studies
Theanine Supportive 12 studies
Productivity Boost
Productivity Boost
Impact
High effect
A- Goal FitB- Strength of SupportA- CoverageC+ Formula Quality
Cordyceps · 400 mgCordyceps · 400 mgCordyceps · 400 mgEleuthero · 100 mgEleuthero · 100 mgTheanine · 100 mg

Rhodiola, ashwagandha, eleuthero, ginseng, cordyceps, and L-theanine create broad support for resilience, fatigue resistance, and calm focus. The formula is strongly aligned with sustained productivity under stress.

L-theanine reaches a useful amount, while most adaptogens are modestly dosed and incompletely standardized. Breadth is impressive, but several secondary botanicals dilute functional depth.

Study evidence
Ashwagandha Supportive 6 studies
Cordyceps Not classified 1 study
Cordyceps Not classified 1 study
Cordyceps Not classified 1 study
Eleuthero No effect 1 study
Eleuthero Not classified

No linked studies yet.

Rhodiola Supportive 7 studies
Theanine Supportive 5 studies
Stress Relief
Stress Relief
Impact
High effect
B+ Goal FitB- Strength of SupportA- CoverageB- Formula Quality
Ashwagandha · 150 mgEleuthero · 100 mgTheanine · 100 mg

A broad adaptogen blend targets both resilience and immediate calm. Ashwagandha, rhodiola, eleuthero, and L-theanine provide direct stress-relevant support.

Most active amounts are disclosed, but several botanicals are modestly dosed and their marker strengths are unclear. The formula has useful breadth, though adrenal tissue and less relevant botanicals dilute its focus.

Study evidence
Ashwagandha Supportive 47 studies
Eleuthero No effect 1 study
Rhodiola Supportive 16 studies
Theanine Supportive 16 studies
Mental Focus
Mental Focus
Impact
High effect
B- Goal FitC+ Strength of SupportB- CoverageB- Formula Quality
Theanine · 100 mg

Rhodiola rosea, eleuthero, ashwagandha, ginseng, cordyceps, and theanine provide broad stress and stamina support. Theanine has a practical amount, while most adaptogens sit at modest blend-level doses rather than strong standalone levels.

The formula may help when fatigue and stress disrupt concentration, but it lacks a clear high-depth alertness or neurotransmitter pathway. Individual amounts are disclosed, although standardization details and the use of bovine adrenal tissue reduce clarity and focus-specific coherence.

Study evidence
Ashwagandha Supportive 12 studies
Eleuthero Disputed 3 studies
Rhodiola Supportive 15 studies
Theanine Supportive 19 studies
Energy
Energy
Impact
High effect
B Goal FitC- Strength of SupportB CoverageC+ Formula Quality
Vitamin B5 · 250 mg

A broad adaptogen blend may support energy when fatigue is tied to stress, with rhodiola, ashwagandha, eleuthero, cordyceps, and a fully disclosed L-theanine amount. It offers little direct mitochondrial support, and several botanicals are supplied at modest or weakly characterized doses.

Individual amounts are disclosed, but most extracts lack marker percentages and the cordyceps is unstandardized raw powder. The bovine adrenal tissue adds uncertain benefit without strengthening the energy evidence.

Study evidence
Ashwagandha Supportive 9 studies
Cordyceps Supportive 2 studies
Eleuthero Disputed 3 studies
Rhodiola Supportive 18 studies
Theanine Not classified

No linked studies yet.

Brain Health
Brain Health
Impact
Moderate effect
C+ Goal FitC Strength of SupportC CoverageC+ Formula Quality
Ashwagandha · 150 mg

Rhodiola, ashwagandha, theanine, ginseng, and eleuthero form an adaptogen-heavy blend for stress resilience and mental fatigue. The cognitive fit is meaningful but indirect, with no dedicated memory or membrane-support ingredient.

Several extract markers are named, yet their percentages are missing and the principal amounts are modest. The formula has a recognizable adrenal-support logic, though many botanicals compete for space and bovine adrenal tissue adds little clear cognitive value.

Study evidence
Ashwagandha Supportive 12 studies
Rhodiola Supportive 8 studies
Theanine Supportive 17 studies

Ingredients

IngredientAmount per serving
Pantothenic Acid (Calcium D-Pantothenate)
 250 mg
Cordyceps sinensis powder
400 mg
Adrenal Tissue (organic Bovine)
 250 mg
Ashwagandha (Withanolides)
 150 mg
Rhodiola rosea (Rosavins)
 100 mg
Siberian Eleuthero (Eleutherosides)
 100 mg
Korean Ginseng (Ginsenosides)
 100 mg
Astragalus membranaceus
100 mg
Epimedium grandiflorum powder
100 mg
L-Theanine (Green Tea)
 100 mg
Ginger (Gingerols)
 50 mg
Beta-Sitosterol
40 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
Theanine (Green Tea) · 100 mg OverallScore76
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The label identifies L-theanine and supplies a transparent amount in the optimal range. The green-tea origin is not paired with standardization, branded sourcing, or a purity claim. The resulting theanine cost is high, and the other ingredients do not meet the stated value exception.

View ingredientView products
Rhodiola (Rosavins) · 100 mg OverallScore61
C Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

Rhodiola rosea is explicitly identified and rosavins are named, but salidroside and extract concentration are not disclosed. The amount suits a lower-dose blend rather than the main effective range. High cost per partially standardized amount and absent excipient details limit value and transparency.

View ingredientView products
Eleuthero (Eleutherosides) · 100 mg OverallScore59
C- Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

The label names eleutherosides but does not state their concentration or identify the Eleuthero plant part. Its exact 100 mg amount is disclosed and reaches the minimum extract-level threshold, though it remains below the preferred range. A particularly high cost per serving makes the effective-dose value weak.

View ingredientView products
Loading alternative details
73 Performance

HPA Adapt

Integrative Therapeutics
The use of substantial Sensoril, rhodiola, eleuthero, holy basil, and branded maca provides stronger ingredient focus or dose depth than the original’s crowded, costly adaptogen formula with bovine adrenal tissue. The deep adaptogen profile avoids glandular tissue, although missing marker percentages and premium cost limit transparency and value.
79 Performance

Cortisol Calm

Pure Encapsulations
The use of standardized ashwagandha, rhodiola, magnolia, and theanine provides stronger ingredient focus or dose depth than the original’s crowded, costly adaptogen formula with bovine adrenal tissue. The focused stress formula uses useful amounts, though duplicate vitamin entries and missing inactive ingredients reduce label polish.
81 Performance

AdrenaSense

Natural Factors WS WomenSense
The use of a concise, marker-identified blend of rhodiola, eleuthero, and ashwagandha provides stronger ingredient focus or dose depth than the original’s crowded, costly adaptogen formula with bovine adrenal tissue. The formula provides clear adaptogen support without animal-derived adrenal tissue.
81 Budget

Adrenal Serenity

Natural Factors Stress-Relax
A lower recurring cost and Sensoril ashwagandha with eleuthero, lavender, and rhodiola improve practical value compared with the original’s crowded, costly adaptogen formula with bovine adrenal tissue. The concise blend avoids bovine adrenal tissue, though some extract details and inactive ingredients remain missing.
76 Budget

Phyto-ADR

Pure Encapsulations
A lower recurring cost and a clearly dosed multi-adaptogen formula using named species and marker compounds improve practical value compared with the original’s crowded, costly adaptogen formula with bovine adrenal tissue. Most individual amounts are modest and some marker percentages or plant-part details remain incomplete.
64 Budget

Steel-Libido Pink For Women

Irwin Naturals
A lower recurring cost and ginseng, maca, damiana, schisandra, velvet bean, and theobromine improve practical value compared with the original’s crowded, costly adaptogen formula with bovine adrenal tissue. The blend avoids glandular tissue but may feel stimulating, and BioPerine adds interaction potential.
72 Value

CalmEssence

Pure Essence
The combination of ashwagandha and theanine with several supporting adaptogens offers a better balance of ingredient utility and recurring value than the original’s crowded, costly adaptogen formula with bovine adrenal tissue. Individual amounts are clear, but most extracts lack marker standardization and several supporting doses are modest.
69 Value

Adrenal Support

Vital Nutrients
The combination of eleuthero, ashwagandha, cordyceps, pantothenic acid, and adrenal ingredients offers a better balance of ingredient utility and recurring value than the original’s crowded, costly adaptogen formula with bovine adrenal tissue. The formula resembles the original but retains bovine glandular tissue and potential adaptogen interactions.
68 Value

Adrenotone

Designs for Health
The combination of adaptogens with active B vitamins for stress-related energy and focus offers a better balance of ingredient utility and recurring value than the original’s crowded, costly adaptogen formula with bovine adrenal tissue. Several lead botanicals are modest or incompletely standardized, while excipient details are missing.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
    McKinney E; Stewart J; Kewalramani R; Singh S · Trials · 2026
    Randomized trial186 participantsEnergy Mood Support forAshwagandha
  2. An Examination into the Anti-stress and Anti-fatigue Effects of an Ashwagandha Extract (Ashwa.30™) in Stressed Adults: A Randomised, Double-Blind, Placebo-controlled Trial.
    Lopresti AL; Smith SJ; Bethapudi B; R AA; Mundkinajeddu D; D'Souza P; Lakshmikanthan S · Advances in therapy · 2026
    Randomized trial60 participantsEnergy forAshwagandha
  3. A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha ( Withania somnifera) in Aging, Overweight Males.
    Lopresti AL; Drummond PD; Smith SJ · American journal of men's health · 2020
    Randomized trial57 participantsEnergy forAshwagandha
  4. The Effect of Short-Term Rhodiola rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players.
    Wang J; Zhao H; Yu L; Zhao K; Jiang W; Liu S; Dai J; Xu L; Sun P; Yun H; Liu C · Nutrients · 2025
    Randomized trial48 participantsEnergy forRhodiola
  5. Scientific Opinion on the substantiation of a health claim related to Rhodiola rosea L. extract and reduction of mental fatigue pursuant to Article 13(5) of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy Stress Relief forRhodiola
  6. Rhodiola rosea for mental and physical fatigue in nursing students: a randomized controlled trial.
    Punja S; Shamseer L; Olson K; Vohra S · PloS one · 2015
    Randomized trial48 participantsEnergy forRhodiola
  7. The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue Conditions: A Randomized, Triple-Blinded, Placebo-Controlled, Crossover Trial.
    Marcos-Frutos D; Leban Ž; Li Z; Zhang X; Lara PM; Alix-Fages C; Jiménez-Martínez P; Zebboudji N; Caillet A; Redondo B; Vera J; Janicijevic D; García-Ramos A · Nutrients · 2025
    Randomized trial18 participantsEnergy forRhodiola
  8. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity.
    Panossian A; Wikman G · Current clinical pharmacology · 2009
    Narrative reviewEnergy Mental Focus forEleuthero Cognitive Support Mental Focus forRhodiola
  9. Randomized controlled trial of Siberian ginseng for chronic fatigue.
    Hartz AJ; Bentler S; Noyes R; Hoehns J; Logemann C; Sinift S; Butani Y; Wang W; Brake K; Ernst M; Kautzman H · Psychological medicine · 2004
    Randomized trial96 participantsEnergy forEleuthero
  10. Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis.
    Fatima K; Malik J; Muskan F; Raza G; Waseem A; Shahid H; Jaffery SF; Khan U; Zaheer MK; Shaikh Y; Rashid AM · Human psychopharmacology · 2024
    Meta-analysis254 participants5 studies pooledStress Relief Mood Support forAshwagandha
  11. The Impact of Ashwagandha on Stress, Sleep Quality, and Food Cravings in College Students: Quantitative Analysis of a Double-Blind Randomized Control Trial.
    O'Connor J; Lindsay K; Baker C; Kirby J; Hutchins A; Harris M · Journal of medicinal food · 2022
    Randomized trial60 participantsStress Relief forAshwagandha
  12. Dual impact of Ashwagandha: Significant cortisol reduction but no effects on perceived stress - A systematic review and meta-analysis.
    Albalawi AA · Nutrition and health · 2025
    Meta-analysis488 participants13 studies pooledStress Relief forAshwagandha
  13. Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes.
    Łuszczak J; Kocki J · Annals of agricultural and environmental medicine : AAEM · 2026
    Systematic review19 studies pooledStress Relief Cognitive Support forRhodiola
  14. [Effects of rhodiola rosea on oxidative stress and negative emotional states in patients with obstructive sleep apnea].
    Yu HL; Zhang PP; Zhang C; Zhang X; Li ZZ; Li WQ; Fu AS · Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2019
    Randomized trial90 participantsStress Relief forRhodiola
  15. L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study.
    Ritsner MS; Miodownik C; Ratner Y; Shleifer T; Mar M; Pintov L; Lerner V · The Journal of clinical psychiatry · 2011
    Randomized trial60 participantsStress Relief Mood Support forTheanine
  16. L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial.
    Sarris J; Byrne GJ; Cribb L; Oliver G; Murphy J; Macdonald P; Nazareth S; Karamacoska D; Galea S; Short A; Ee C; Birling Y; Menon R; Ng CH · Journal of psychiatric research · 2020
    Randomized trial46 participantsStress Relief Sleep Support forTheanine
  17. Effect of Combined Ingestion of L-Theanine and L-Arginine for Short-Term Psychological Stress in Young Adults: A Randomized Placebo-Controlled Study.
    Furushima D; Sugiyama I; Nomura Y; Unno K; Yamada H · Journal of nutritional science and vitaminology · 2023
    Randomized trial120 participantsStress Relief forTheanine
  18. Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
    Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
    Randomized trial59 participantsBrain Health Cognitive Support Energy forAshwagandha
  19. Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
    Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
    Randomized trial40 participantsBrain Health Cognitive Support Mental Focus forAshwagandha
  20. Efficacy of Withania somnifera supplementation on adult's cognition and mood.
    Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
    Randomized trial60 participantsBrain Health Cognitive Support Productivity Boost forAshwagandha
  21. A clinical assessment of the therapeutic effects of Ashwagandha root extract on cognitive performance, sleep, and fatigue in children aged 6-12 years.
    Saxena A; Lopresti A; Sharif M; Elon N; Suri R; Langade DK · Frontiers in nutrition · 2026
    Randomized trial85 participantsBrain Health Mental Focus forAshwagandha
  22. Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study.
    Gopukumar K; Thanawala S; Somepalli V; Rao TSS; Thamatam VB; Chauhan S · Evidence-based complementary and alternative medicine : eCAM · 2022
    Randomized trial130 participantsBrain Health Sleep Support Stress Relief forAshwagandha
  23. Dose-Response Effects of Short-Term Rhodiola rosea (Golden Root Extract) Supplementation on Anaerobic Exercise Performance and Cognitive Function in Resistance-Trained Athletes: A Randomized, Crossover, Double-Blind, and Placebo-Controlled Study.
    Koozehchian MS; Newton AT; Mabrey G; Bonness FM; Rafajlovska R; Naderi A · Nutrients · 2025
    Randomized trial27 participantsBrain Health Mental Focus forRhodiola
  24. A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers.
    Boyle NB; Billington J; Lawton C; Quadt F; Dye L · Nutritional neuroscience · 2022
    Randomized trial100 participantsBrain Health forRhodiola
  25. Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy.
    Panossian A; Wikman G; Sarris J · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2010
    Narrative reviewBrain Health forRhodiola
  26. Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.
    Darbinyan V; Kteyan A; Panossian A; Gabrielian E; Wikman G; Wagner H · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2001
    Randomized trial56 participantsBrain Health Productivity Boost forRhodiola
  27. Effects of a Rhodiola rosea extract on mental resource allocation and attention: An event-related potential dual task study.
    Koop T; Dienel A; Heldmann M; Münte TF · Phytotherapy research : PTR · 2021
    Single-arm trial50 participantsBrain Health Cognitive Support forRhodiola
  28. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
    Hidese S; Ogawa S; Ota M; Ishida I; Yasukawa Z; Ozeki M; Kunugi H · Nutrients · 2020
    Randomized trial30 participantsBrain Health Cognitive Support Sleep Support forTheanine
  29. A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWave® L-Theanine on Stress in a Healthy Adult Population.
    Evans M; McDonald AC; Xiong L; Crowley DC; Guthrie N · Neurology and therapy · 2021
    Randomized trialBrain Health Stress Relief forTheanine
  30. Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Payne ER; Aceves-Martins M; Dubost J; Greyling A; de Roos B · Nutrition reviews · 2025
    Meta-analysis50 studies pooledBrain Health Cognitive Support Mental Focus forTheanine
  31. Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task.
    Foxe JJ; Morie KP; Laud PJ; Rowson MJ; de Bruin EA; Kelly SP · Neuropharmacology · 2012
    Randomized trial27 participantsBrain Health Cognitive Support forTheanine
  32. Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study.
    Baba Y; Inagaki S; Nakagawa S; Kaneko T; Kobayashi M; Takihara T · Journal of medicinal food · 2021
    Randomized trialBrain Health Mental Focus Productivity Boost forTheanine
  33. A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.
    Majeed M; Nagabhushanam K; Mundkur L · Medicine · 2023
    Randomized trial54 participantsCognitive Support Mental Focus forAshwagandha
  34. Efficacy and safety of ashwagandha root extract in children and adolescents with mild attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled trial.
    Naik S; Muralidhar G; Rao BS; Agarwal S; Jain M · Journal of medicine and life · 2026
    Randomized trial58 participantsCognitive Support Mental Focus forAshwagandha
  35. No benefit adding eleutherococcus senticosus to stress management training in stress-related fatigue/weakness, impaired work or concentration, a randomized controlled study.
    Schaffler K; Wolf OT; Burkart M · Pharmacopsychiatry · 2014
    Randomized trial144 participantsCognitive Support Mental Focus Productivity Boost Stress Relief forEleuthero
  36. Central additive effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy.
    Al-Kuraishy HM · Journal of intercultural ethnopharmacology · 2016
    Clinical trial112 participantsCognitive Support forRhodiola
  37. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.
    Olsson EM; von Schéele B; Panossian AG · Planta medica · 2009
    Randomized trial60 participantsCognitive Support Productivity Boost forRhodiola
  38. Dose-response effect of L-theanine on psychomotor speed, sustained attention, and inhibitory control: a double-blind, placebo-controlled, crossover study.
    Dassanayake TL; Wijesundara D; Kahathuduwa CN; Weerasinghe VS · Nutritional neuroscience · 2023
    Randomized trial32 participantsCognitive Support forTheanine
  39. Acute effects of theanine, caffeine and theanine-caffeine combination on attention.
    Kahathuduwa CN; Dassanayake TL; Amarakoon AMT; Weerasinghe VS · Nutritional neuroscience · 2018
    Clinical trial20 participantsCognitive Support Mental Focus forTheanine
  40. Efficacy and Safety of Low-Dose Ashwagandha Supplementation on Exercise Endurance: A Randomized, Placebo-Controlled, Double-Blind, Clinical Trial.
    Prajapati H; Satia M; Shah D; Basera I; Shah T · Phytotherapy research : PTR · 2026
    Randomized trialEnergy forAshwagandha
  41. Enhancing healthspan with Ashwagandha (Withania somnifera): a comprehensive review of its multifaceted geroprotective benefits.
    Vittal M; Vinciguerra M · Biogerontology · 2025
    Narrative reviewEnergy forAshwagandha
  42. Safety and Efficacy of Ashwagandha Root Extract on Cognition, Energy and Mood Problems in Adults: Prospective, Randomized, Placebo-Controlled Study.
    Kale S; Lopresti A; Suri R; Garg N; Langade D · Journal of psychoactive drugs · 2026
    Randomized trial120 participantsEnergy Productivity Boost forAshwagandha
  43. Effects of fungal supplementation on endurance, immune function, and hematological profiles in adult athletes: a systematic review and meta-analysis
    Meng-Yuan Shu, Xiu-Chang Zhang, Li Zuo, Fang-Lin Jiang, Jian Liang, Fang Li · Frontiers in Nutrition · 2025
    Meta-analysis34 participants2 studies pooledEnergy forCordyceps
  44. Effect of Cs-4 (Cordyceps sinensis) on exercise performance in healthy older subjects: a double-blind, placebo-controlled trial
    Steve Chen, Zhaoping Li, Robert Krochmal, Marlon Abrazado, Woosong Kim, Christopher B Cooper · Journal of Alternative and Complementary Medicine · 2010
    Randomized trialEnergy forCordyceps
  45. The effect of eight weeks of supplementation with Eleutherococcus senticosus on endurance capacity and metabolism in human
    J Kuo, K W Chen, I S Cheng, P H Tsai, Y J Lu, N Y Lee · Chinese Journal of Physiology · 2010
    Randomized trial9 participantsEnergy forEleuthero
  46. Effects of Rhodiola rosea on Physical and Decision-Making Performance in Football Players: A Randomised Controlled Trial.
    Dou Y; Wang Y; Zhang W; Jiang Y; Zhang J; Yang T; Han Z; Li Y; Liu C; Ren D · Nutrients · 2026
    Randomized trial24 participantsEnergy Mental Focus forRhodiola
  47. Combined Effects of Rhodiola Rosea and Caffeine Supplementation on Straight Punch Explosive Power in Untrained and Trained Boxing Volunteers: A Synergistic Approach.
    Tao B; Sun H; Li H; Xu Z; Xu Y; Chen L; Ma C; Zhang X; Yu L; Bao S; Liu C · Metabolites · 2025
    Randomized trial96 participantsEnergy forRhodiola
  48. Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial.
    Lekomtseva Y; Zhukova I; Wacker A · Complementary medicine research · 2019
    Single-arm trial100 participantsEnergy Stress Relief forRhodiola
  49. Combined Rhodiola rosea and eccentric training boost endurance performance and lower-limb reactive strength in recreationally active women.
    Wang IL; Su Y; Zhang L; Tang M; Chen YM · Frontiers in physiology · 2025
    Randomized trial30 participantsEnergy forRhodiola
  50. Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions.
    Choudhary D; Bhattacharyya S; Bose S · Journal of dietary supplements · 2018
    Randomized trial50 participantsMental Focus forAshwagandha
  51. Stimulating effect of adaptogens: an overview with particular reference to their efficacy following single dose administration.
    Panossian A; Wagner H · Phytotherapy research : PTR · 2005
    Narrative reviewMental Focus forEleuthero
  52. The effectiveness and efficacy of Rhodiola rosea L.: a systematic review of randomized clinical trials.
    Hung SK; Perry R; Ernst E · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
    Systematic review11 studies pooledMental Focus forRhodiola
  53. Effects of Rhodiola rosea supplementation on mental performance, physical capacity, and oxidative stress biomarkers in healthy men.
    Jówko E; Sadowski J; Długołęcka B; Gierczuk D; Opaszowski B; Cieśliński I · Journal of sport and health science · 2022
    Randomized trial26 participantsMental Focus Productivity Boost forRhodiola
  54. Safety and Efficacy of AlphaWave® L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Moulin M; Crowley DC; Xiong L; Guthrie N; Lewis ED · Neurology and therapy · 2024
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    Karunaratne UW; Dassanayake TL · Nutritional neuroscience · 2025
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    Chandrasekhar K; Kapoor J; Anishetty S · Indian journal of psychological medicine · 2013
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    Zhang W; Yan Y; Wu Y; Yang H; Zhu P; Yan F; Zhao R; Tian P; Wang T; Fan Q; Su Z · Pharmacological research · 2022
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    Meta-analysis1,049 participants2 studies pooledMood Support forRhodiola
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    Duncan MJ; Clarke ND · Journal of sports medicine (Hindawi Publishing Corporation) · 2015
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    Sarris J; Panossian A; Schweitzer I; Stough C; Scholey A · European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2012
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    Moragrega I; Ríos JL · Planta medica · 2022
    Systematic reviewMood Support forRhodiola
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    Kasper S; Dienel A · Neuropsychiatric disease and treatment · 2020
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    Shamabadi A; Kafi F; Arab Bafrani M; Asadigandomani H; A Basti F; Akhondzadeh S · Journal of affective disorders · 2023
    Randomized trial60 participantsMood Support forTheanine
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    Williams JL; Everett JM; D'Cunha NM; Sergi D; Georgousopoulou EN; Keegan RJ; McKune AJ; Mellor DD; Anstice N; Naumovski N · Plant foods for human nutrition (Dordrecht, Netherlands) · 2020
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    Unno K; Tanida N; Ishii N; Yamamoto H; Iguchi K; Hoshino M; Takeda A; Ozawa H; Ohkubo T; Juneja LR; Yamada H · Pharmacology, biochemistry, and behavior · 2014
    Randomized trial20 participantsMood Support forTheanine
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    Cheah KL; Norhayati MN; Husniati Yaacob L; Abdul Rahman R · PloS one · 2021
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    Pingali U; Pilli R; Fatima N · Pharmacognosy research · 2014
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    Hamidreza Farzan, Maryam Koushkie Jahromi · PLOS ONE · 2026
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    Spasov AA; Wikman GK; Mandrikov VB; Mironova IA; Neumoin VV · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2000
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    Ivanova Stojcheva E; Quintela JC · Molecules (Basel, Switzerland) · 2022
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    Gerolymos C; Saddier E; Boyer L; Fond G · Molecular psychiatry · 2026
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    Cotter J; Kilpatrick HE · Frontiers in nutrition · 2026
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    Rogers PJ; Smith JE; Heatherley SV; Pleydell-Pearce CW · Psychopharmacology · 2008
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  78. Efficacy and safety of Ashwagandha root extract sustained-release (AshwaSR) capsules in healthy adult, stressed subjects: A randomized, double-blind, placebo-controlled, parallel-group, 3-arm clinical trial.
    Thanawala S; Shah R; Alluri KV; Bhupathiraju K; Desomayanandanam P; Bhuvenendran A · Medicine · 2026
    Randomized trial135 participantsSleep Support forAshwagandha
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    Langade D; Kanchi S; Salve J; Debnath K; Ambegaokar D · Cureus · 2020
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    Kurdi MS; As A; Ladhad DA; Mitragotri MV; Baiju A · Indian journal of palliative care · 2024
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    Bulman A; D'Cunha NM; Marx W; Turner M; McKune A; Naumovski N · Sleep medicine reviews · 2025
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    Rao TP; Ozeki M; Juneja LR · Journal of the American College of Nutrition · 2016
    Narrative reviewSleep Support forTheanine
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    Lopresti AL; Smith SJ; Malvi H; Kodgule R · Medicine · 2019
    Randomized trial60 participantsStress Relief forAshwagandha
  84. Shoden promotes Relief from stress and anxiety: A randomized, double-blind, placebo-controlled study on healthy subjects with high stress levels.
    Mishra DN; Kumar M · Heliyon · 2024
    Randomized trial60 participantsStress Relief forAshwagandha
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    Salve J; Pate S; Debnath K; Langade D · Cureus · 2020
    Randomized trial60 participantsStress Relief forAshwagandha
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    Anghelescu IG; Edwards D; Seifritz E; Kasper S · International journal of psychiatry in clinical practice · 2019
    Narrative reviewStress Relief forRhodiola
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    Sarris J; McIntyre E; Camfield DA · CNS drugs · 2013
    Narrative reviewStress Relief forRhodiola
  88. Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial.
    White DJ; de Klerk S; Woods W; Gondalia S; Noonan C; Scholey AB · Nutrients · 2016
    Randomized trial34 participantsStress Relief forTheanine