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L-Glutathione 500 mg

AN Amazing Nutrition Amazing Formulas
4.6
★ ★ ★ ★ ★
(73 ratings)
Gluthathione 500 mg
Product Image
Score76
A substantial single-ingredient serving makes the formula simple and easy to assess. Missing form and delivery details create meaningful uncertainty about absorption.
How scoring works
Quantity:60 Vcap(s) • (60 servings)
Goals:
Skin Health

Score 76

A substantial single-ingredient serving makes the formula simple and easy to assess. Missing form and delivery details create meaningful uncertainty about absorption.
How scoring works
$14.99($0.24 per serving)
Pure Formulas
$ 19.98
Vitacost
$ 17.99
Walmart
$ 14.99
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Analysis

A single 500 mg glutathione serving gives the product a clear antioxidant purpose without unrelated additions. The amount is substantial enough to be more than a token inclusion.

The main limitation is form disclosure because the label does not say reduced, acetylated, or liposomal glutathione. Oral performance can depend on delivery, so material weight alone does not establish how much usable glutathione reaches the body.

Skin-focused users may value antioxidant support, but the formula does not address collagen structure, barrier lipids, or hydration. It is best treated as a basic direct-glutathione option rather than a complete skin formula.

Who is it for
  • Adults seeking basic antioxidant supplementation
  • Users who prefer single-ingredient capsules
  • Skin-focused shoppers who already cover structural and hydration support elsewhere
Best for
  • Simple direct glutathione intake
  • Avoiding complex antioxidant blends
  • Users prioritizing dose quantity over enhanced delivery

Pros

  • Provides 500 mg of glutathione
  • Single-active formula avoids padding
  • Clear ingredient quantity
  • Convenient capsule format

Cons

  • Reduced form is not confirmed
  • No liposomal or acetylated delivery is identified
  • No branded source or purity information is supplied
  • Does not support collagen structure or skin hydration

Nutrient quality

75 High impact

Generic L-glutathione lacks a reduced, liposomal, or acetylated form that would strengthen absorption confidence. The substantial direct glutathione amount provides strong nominal dose depth.

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Ingredient transparency

78 High impact

Every listed active ingredient has a specific amount. Usage and inactive-ingredient details remain incomplete.

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Customer satisfaction

61 Moderate impact

The average rating is consistently strong. The moderate feedback pool provides useful but limited confidence.

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Value for money

85 Highest impact

The large nominal dose supports the modest price despite uncertain absorption. Low serving cost creates good practical value.

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Goals

Skin Health
Skin Health
Impact
Moderate effect
C Goal FitC Strength of SupportD CoverageA Formula Quality
Gluthathione · 500 mg

Glutathione provides antioxidant support that may help the skin manage oxidative stress. Its role is narrower and less directly established than collagen peptides, ceramides, or proven hydration ingredients.

The amount is substantial, but the label does not identify a reduced, liposomal, or acetylated form. The simple formula avoids padding while leaving oral absorption and skin-specific effectiveness uncertain.

Study evidence
Gluthathione Supportive 13 studies

Ingredients

IngredientAmount per serving
L-Glutathione
500 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
Gluthathione · 500 mg OverallScore42
F Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyC Value
A large direct glutathione dose and low serving cost are practical strengths. The label does not confirm reduced, liposomal, or acetylated delivery, so absorption quality remains uncertain. No branded source or purity testing is disclosed.
View ingredientView products
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84 Performance

L-Glutathione (Reduced) 500 mg

California Gold Nutrition
<p>Its label clearly provides 500 mg of L-Glutathione, Reduced, making it a more clearly defined glutathione option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
76 Performance

Reduced Glutathione 250 mg

Source Naturals
<p>Its label clearly provides 250 mg of L-Glutathione, Reduced, making it a more clearly defined glutathione option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
74 Performance

Optimal Liposomal Glutathione Plus

Seeking Health
<p>Its label clearly provides 350 mg of L-Glutathione, making it a more clearly defined glutathione option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
79 Budget

Glutathione 500 mg

Nutricost
<p>Its label clearly provides 500 mg of L-Glutathione, preserving relevant glutathione coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
76 Budget

L-Glutathione 500 mg

AN Amazing Nutrition Amazing Formulas
<p>Its label clearly provides 500 mg of L-Glutathione, preserving relevant glutathione coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
73 Budget

Chem-Defense Orange Flavored

Source Naturals
<p>Its label clearly provides 50 mg of L-Glutathione, preserving relevant glutathione coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
72 Value

L-Glutathione 100 mg

Bluebonnet
<p>Its label clearly provides 100 mg of L-Glutathione, Reduced, keeping the formula relevant to glutathione. Compared with the original, the somewhat higher serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
79 Value

Mega-Liposomal Glutathione+ 750 mg Organic Fruit Flavor

Aurora NutraScience
<p>Its label clearly provides 750 mg of L-Glutathione, keeping the formula relevant to glutathione. Compared with the original, the somewhat higher serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
75 Value

Reduced Glutathione Complex 50 mg Orange Flavored

Source Naturals
<p>Its label clearly provides 50 mg of L-Glutathione, keeping the formula relevant to glutathione. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The clinical effect of glutathione on skin color and other related skin conditions: A systematic review.
    Dilokthornsakul W; Dhippayom T; Dilokthornsakul P · Journal of cosmetic dermatology · 2019
    Systematic review4 studies pooledSkin Health forGluthathione
  2. Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study.
    Arjinpathana N; Asawanonda P · The Journal of dermatological treatment · 2012
    Randomized trial60 participantsSkin Health forGluthathione
  3. Systemic Glutathione as a Skin-Whitening Agent in Adult.
    Sitohang IBS; Ninditya S · Dermatology research and practice · 2022
    Systematic review3 studies pooledSkin Health forGluthathione
  4. The effects of the oral supplementation of L-Cystine associated with reduced L-Glutathione-GSH on human skin pigmentation: a randomized, double-blinded, benchmark- and placebo-controlled clinical trial.
    Duperray J; Sergheraert R; Chalothorn K; Tachalerdmanee P; Perin F · Journal of cosmetic dermatology · 2022
    Randomized trial124 participantsSkin Health forGluthathione
  5. Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women.
    Watanabe F; Hashizume E; Chan GP; Kamimura A · Clinical, cosmetic and investigational dermatology · 2014
    Randomized trial30 participantsSkin Health forGluthathione
  6. Systematic Review of the Efficacy and Safety of Topical Glutathione in Dermatology.
    Khanna R; Rambhia P; Chapas A · The Journal of clinical and aesthetic dermatology · 2025
    Systematic review5 studies pooledSkin Health forGluthathione
  7. Effects of antioxidants on glutathione levels and clinical recovery from the malnutrition syndrome kwashiorkor--a pilot study.
    Becker K; Pons-Kühnemann J; Fechner A; Funk M; Gromer S; Gross HJ; Grünert A; Schirmer RH · Redox report : communications in free radical research · 2006
    Randomized trialSkin Health forGluthathione
  8. Glutathione and its antiaging and antimelanogenic effects.
    Weschawalit S; Thongthip S; Phutrakool P; Asawanonda P · Clinical, cosmetic and investigational dermatology · 2020
    Randomized trial57 participantsSkin Health forGluthathione