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L-Citrulline 2000 mg

4.4
★ ★ ★ ★ ★
(1273 ratings)
Citrulline 2000 mg
Product Image
Score83
A well-priced, single-ingredient citrulline option with a useful moderate dose, though exercise-focused users may still need more than one serving.
How scoring works
Quantity:120 Tablet(s) • (60 servings)
Goals:
Cardiovascular Support
Heart Health

Score 83

A well-priced, single-ingredient citrulline option with a useful moderate dose, though exercise-focused users may still need more than one serving.
How scoring works
$14.99($0.24 per serving)
Vitacost
$ 16.99
iHerb
$ 16.49
Amazon
$ 19.99
Pure Formulas
$ 14.99
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Analysis

L-citrulline is supplied as the only active at 2,000 mg per serving. Clear dose disclosure makes the formula easy to compare and use consistently.

The amount may suit moderate circulation support or serve as a starting point before exercise. People seeking a larger pre-workout amount would still need extra tablets, which reduces convenience.

Cost efficiency is a clear strength for the amount provided. The trade-off is a generic source with no stated purity marker or distinctive delivery feature.

Who is it for
  • Adults seeking moderate citrulline support
  • Value-focused users comfortable with tablets
Best for
  • A simple daily citrulline routine
  • Flexible circulation or workout support

Pros

  • Provides 2,000 mg of L-citrulline per serving
  • Keeps the formula focused on one active
  • Offers strong dose-adjusted value

Cons

  • Falls below many larger exercise-oriented servings
  • Extra tablets are needed for higher intake
  • No branded source or purity standard is listed

Warnings

  • L-citrulline may add to the effects of antihypertensive medicine and cause lightheadedness.
  • Combining it with nitrate medicine or erectile-dysfunction medicine may lower blood pressure further.
  • Higher self-selected servings may cause stomach discomfort or loose stools.

Nutrient quality

85 Highest impact

Pure L-citrulline is a useful and straightforward form. The moderate dose falls short of peak-performance amounts.

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Ingredient transparency

85 Highest impact

The active identity and amount are clear without a hidden blend. Complete directions, inactive ingredients, and source-quality markers remain missing.

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Customer satisfaction

68 High impact

The supplied average is good but not exceptional and supported by substantial volume. No review themes were provided, so consistency and purpose-specific experience cannot be assessed.

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Value for money

90 Highest impact

A clean formula and accessible cost support good value. The low amount per serving still limits peak-performance efficiency.

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Report analysis

Goals

Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
A- Goal FitB+ Strength of SupportC- CoverageA+ Formula Quality
Citrulline · 2000 mg

L-citrulline directly supports nitric oxide production and blood-vessel relaxation. The focused formula does not address lipids, cardiac energy, inflammation, or rhythm.

The disclosed amount may contribute to circulation but is below amounts commonly used for stronger vascular effects. Its single-active design is clear and free from unnecessary additions.

Study evidence
Citrulline Supportive 33 studies
Heart Health
Heart Health
Impact
High effect
A- Goal FitB Strength of SupportC- CoverageA+ Formula Quality
Citrulline · 2000 mg

L-citrulline directly supports nitric oxide production and vascular relaxation. Human evidence is useful for blood flow and selected blood-pressure outcomes.

The 2,000 mg amount is a solid maintenance dose but below many higher clinical or performance protocols. The simple formula covers vascular tone well without adding lipid, cardiac-energy, or homocysteine support.

Study evidence
Citrulline Supportive 39 studies

Ingredients

IngredientAmount per serving
L-Citrulline
2000 mg
Adults 18–50
Report overview
Citrulline · 2000 mg OverallScore89
A- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value

Pure L-citrulline is clearly listed at a solid maintenance dose, though it falls short of the range commonly used for peak exercise support. The simple single-ingredient formula suggests good ingredient integrity, but no branded or tested source is identified. Two tablets provide excellent cost efficiency for the active amount.

View ingredientView products
Loading alternative details
67 Performance

Pump-Ocalypse Blue Raz

Bucked Up
<p>Glycerol, citrulline, arginine, and agmatine form a coherent stimulant-free pump blend. Compared with L-Citrulline 2000 mg, the broader hydration and nitric-oxide ingredient profile provides a stronger ingredient-based fit for nitric-oxide or exercise support, although several amounts are moderate and a mushroom blend is opaque.</p>
65 Performance

High Volume Blue Frost

PEScience
<p>L-citrulline, arginine nitrate, and agmatine create a substantial stimulant-free pump formula. Compared with L-Citrulline 2000 mg, the broader pump-oriented combination of citrulline, nitrate, and agmatine provides a stronger ingredient-based fit for nitric-oxide or exercise support, although part of the matrix is hidden and arginine nitrate may interact with nitrate or blood-pressure medicines.</p>
76 Performance

Arginine Citrulline

MNP Michael's Naturopathic Programs
<p>A substantial arginine amount is combined with citrulline and beet for focused circulation support. Compared with L-Citrulline 2000 mg, the larger arginine base with complementary citrulline and beet provides a stronger ingredient-based fit for nitric-oxide or exercise support, although the serving is costly and the vasodilating ingredients may add to nitrate or blood-pressure medicines.</p>
79 Budget

L-Arginine + L-Citrulline 750 mg

Nutricost
<p>Clearly separated L-arginine and L-citrulline provide a simple nitric-oxide-support combination. Its lower cost per serving than L-Citrulline 2000 mg makes it a more economical choice, although both amounts are too low for targeted performance use without multiple capsules.</p>
78 Budget

L-Arginine L-Citrulline Complex 1000 mg

Best Naturals
<p>L-arginine hydrochloride and free-form L-citrulline create a focused two-amino-acid formula. Its lower cost per serving than L-Citrulline 2000 mg makes it a more economical choice, although the citrulline amount is far below targeted performance use.</p>
78 Budget

Arginine & Citrulline 500 mg / 250 mg

NOW Sports
<p>Clearly disclosed L-arginine and L-citrulline provide a concise nitric-oxide-support formula. Its lower cost per serving than L-Citrulline 2000 mg makes it a more economical choice, although both serving amounts are far below targeted performance ranges.</p>
79 Value

L-Citrulline 1000 mg

Nutricost
<p>Pure L-citrulline provides a clean and transparent single-ingredient formula. Compared with L-Citrulline 2000 mg, its lower serving cost and the simple formula and clearly disclosed citrulline amount support a more favorable quality-to-cost balance, although the amount remains below common performance use.</p>
77 Value

L-Citrulline 500 mg

California Gold Nutrition
<p>Pure L-citrulline provides a clean, easy-to-assess single-ingredient formula. Compared with L-Citrulline 2000 mg, its lower serving cost and the transparent single-ingredient design support a more favorable quality-to-cost balance, although the citrulline amount is well below common performance use.</p>
78 Value

L-Arginine L-Citrulline Complex

Source Naturals
<p>A focused L-arginine and L-citrulline combination offers clearly disclosed amino-acid support. Compared with L-Citrulline 2000 mg, its lower serving cost and the concise arginine-citrulline pairing support a more favorable quality-to-cost balance, although citrulline is far below targeted use and arginine may add to blood-pressure-lowering medicines.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of L-citrulline supplementation on blood pressure: A systematic review and meta-analysis.
    Barkhidarian B; Khorshidi M; Shab-Bidar S; Hashemi B · Avicenna journal of phytomedicine · 2022
    Meta-analysis8 studies pooledHeart Health forCitrulline
  2. Citrulline supplementation in postmenopausal women: a systematic review of vascular, muscular, and metabolic effects.
    Bahari H; Ramezani E; Malekahmadi M · BMC women's health · 2026
    Systematic review360 participants12 studies pooledHeart Health forCitrulline
  3. Oral L-citrulline supplementation attenuates blood pressure response to cold pressor test in young men.
    Figueroa A; Trivino JA; Sanchez-Gonzalez MA; Vicil F · American journal of hypertension · 2010
    Randomized trial17 participantsCardiovascular Support forCitrulline
  4. Oral citrulline supplementation in pregnancies with preeclampsia: a multicenter, randomized, double-blind clinical trial.
    Winer N; Misbert E; Masson D; Girault A; Alexandre-Gouabau MC; Ducarme G; Dochez V; Thubert T; Boivin M; Ferchaud-Roucher V; Péré M; Darmaun D · The American journal of clinical nutrition · 2025
    Randomized trial115 participantsCardiovascular Support forCitrulline
  5. Does l-citrulline supplementation and watermelon intake reduce blood pressure in middle-aged and older adults? A systematic review and meta-analysis of randomized controlled trials.
    Luo P; Chen J; Liu K; Zhang J · Clinical nutrition ESPEN · 2025
    Meta-analysis415 participants15 studies pooledCardiovascular Support forCitrulline
  6. Micronutrient Supplementation to Reduce Cardiovascular Risk.
    An P; Wan S; Luo Y; Luo J; Zhang X; Zhou S; Xu T; He J; Mechanick JI; Wu WC; Ren F; Liu S · Journal of the American College of Cardiology · 2022
    Meta-analysis883,627 participants884 studies pooledCardiovascular Support forCitrulline
  7. l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans.
    Bailey SJ; Blackwell JR; Lord T; Vanhatalo A; Winyard PG; Jones AM · Journal of applied physiology (Bethesda, Md. : 1985) · 2016
    Randomized trial10 participantsCardiovascular Support forCitrulline
  8. Effects of L-Citrulline Supplementation on Endothelial Function and Blood Pressure in Hypertensive Postmenopausal Women.
    Maharaj A; Fischer SM; Dillon KN; Kang Y; Martinez MA; Figueroa A · Nutrients · 2022
    Randomized trial25 participantsCardiovascular Support Heart Health forCitrulline
  9. Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged men.
    Ochiai M; Hayashi T; Morita M; Ina K; Maeda M; Watanabe F; Morishita K · International journal of cardiology · 2012
    Randomized trial15 participantsCardiovascular Support forCitrulline
  10. Effect of oral L-citrulline on brachial and aortic blood pressure defined by resting status: evidence from randomized controlled trials.
    Yang HH; Li XL; Zhang WG; Figueroa A; Chen LH; Qin LQ · Nutrition & metabolism · 2022
    Meta-analysis8 studies pooledHeart Health forCitrulline
  11. Impact of L-Citrulline Supplementation and HIIT on Lipid Profile, Arterial Stiffness, and Fat Mass in Obese Adolescents with Metabolic-Dysfunction-Associated Fatty Liver Disease: A Randomized Clinical Trial.
    Rodríguez-Carrillo AA; Espinoza-Vargas MR; Vargas-Ortiz K; Ibarra-Reynoso LDR; Olvera-Juárez M; Gómez-Ojeda A; Garay-Sevilla ME; Figueroa A · Nutrients · 2025
    Randomized trial44 participantsHeart Health forCitrulline
  12. Vascular effects of l-citrulline supplementation in healthy adults are largely influenced by the prehypertensive range of blood pressure: A double-blind, randomized, placebo-controlled, parallel-group study.
    Nogimura D; Nagaoka K; Ogino K; Ogino N; Moriyasu K; Morita M · Nutrition research (New York, N.Y.) · 2026
    Randomized trial66 participantsHeart Health forCitrulline
  13. The Assessment of short-term effect of L-Citrulline on endothelial function via FMD to NMD ratio in known CAD patients: A randomized, cross-over clinical trial (Clinical trial number: NCT02638727).
    Safi M; Mahjoob MP; Nateghi S; Khaheshi I; Akbarzadeh MA; Naderian M · Romanian journal of internal medicine = Revue roumaine de medecine interne · 2017
    Randomized trial30 participantsHeart Health forCitrulline