Advanced BP Support

Advanced BP Support

Dr. Sinatra4.7 (51 ratings)
Format:Capsule Quantity: 120 Capsule(s) · 30 servings
Goals
$36.99 $1.23 per serving
iHerb$36.99 Buy

About this product

Magnesium at 250 mg uses three well-absorbed forms and supports vascular, muscle, and nerve function. Hawthorn extract at 600 mg and grape-seed extract at 150 mg give the formula a clear cardiovascular direction.

GABA contributes only 50 mg and is unlikely to drive the effect. Hawthorn species, plant part, and active-marker standardization are not supplied.

The four-capsule serving fits users seeking a combined magnesium-and-hawthorn approach. People already using blood-pressure or heart medicines need more caution than they would with a simple magnesium product.

Who is it for
  • Adults seeking magnesium with hawthorn
  • Users focused on cardiovascular nutrition
  • People comfortable with four capsules
Best for
  • Magnesium-based cardiovascular support
  • Hawthorn supplementation
  • Vascular antioxidant coverage

Pros

  • Uses citrate, glycinate, and malate
  • Provides 250 mg magnesium
  • Substantial hawthorn amount
  • Includes grape-seed extract

Cons

  • Hawthorn is not standardized
  • GABA amount is small
  • Four-capsule serving
  • Premium serving cost

Warnings

  • Hawthorn may add to antihypertensive or heart medicines and cause excessive blood-pressure lowering.
  • Magnesium can interfere with absorption of levothyroxine and some antibiotics when taken too close together.
  • The 250 mg magnesium amount may cause loose stools or cramping in sensitive users.

Product analysis

67 out of 100
Well-formed magnesium and substantial hawthorn provide focused cardiovascular support. Incomplete hawthorn standardization and medication interactions are the main drawbacks.

AI assessment of the formula, label and price. How scoring works

Nutrient quality78

Favorable magnesium forms and meaningful primary doses support cardiovascular use. Missing botanical standardization and a medication-related caution temper the formula.

.
Ingredient transparency73

All active weights and magnesium forms are disclosed without a hidden blend. Botanical potency, full directions, and inactive ingredients remain unreported.

.
Customer satisfaction59

The average customer rating is very strong. A modest rating base limits confidence in the average, while specific review experiences were not supplied.

.
Value for money54

Meaningful doses and useful magnesium forms add formula value. High serving cost and unstandardized botanicals weaken competitiveness.

.
Format
Capsule
Container
120 Capsule(s)
Per serving
$1.23
Customer rating
4.7 · 51 ratings
Report analysis

Goals

Cardiovascular Support
Blood Flow and CirculationHeart Muscle and Rhythm
Cardiovascular Support
Impact
Highest effect
A- Goal FitA- Strength of SupportA- CoverageA- Formula Quality
Magnesium · 250 mgHawthorn · 600 mg

Hawthorn and magnesium directly support vascular tone, circulation, and normal cardiac rhythm. Both actives are present at meaningful amounts, giving the formula a clear cardiovascular purpose.

Glycinate, citrate, and malate improve the magnesium profile, while grape seed extract adds antioxidant coverage. Hawthorn standardization and species are not disclosed, so botanical quality remains less certain.

Study evidence
Hawthorn Supportive 28 studies
Magnesium Supportive 123 studies
Heart Health
Healthy Blood Pressure
Heart Health
Impact
Highest effect
A- Goal FitA- Strength of SupportB+ CoverageA Formula Quality
Magnesium · 250 mg

Magnesium, hawthorn, and grape-seed extract directly support vascular tone and blood-pressure pathways. Magnesium has strong evidence, while hawthorn and grape-seed evidence is promising but less definitive.

Magnesium and hawthorn are supplied at meaningful amounts, with substantial grape-seed support. Citrate, glycinate, and malate are useful magnesium forms, but hawthorn lacks species and active-marker detail.

Study evidence
Hawthorn Supportive 27 studies
Magnesium Supportive 158 studies
General Health
Stress Resilience
General Health
Impact
Highest effect
B Goal FitA Strength of SupportC+ CoverageA Formula Quality
Magnesium · 250 mg

Well-dosed magnesium in citrate, glycinate, and malate forms supports foundational metabolic, nerve, and muscle functions. Hawthorn and grape seed extract give the formula a more targeted cardiovascular direction.

The magnesium forms and elemental amount are clearly disclosed and generally well absorbed. The blend is coherent, though its narrower blood-pressure focus does not provide broad micronutrient coverage.

Study evidence
Magnesium Supportive 114 studies
Energy
Energy
Impact
High effect
C+ Goal FitA- Strength of SupportC+ CoverageB Formula Quality
Magnesium · 250 mg

A 250 mg magnesium amount in citrate, glycinate, and malate forms supports cellular energy reactions with good absorption potential. Hawthorn, grape seed, and GABA are aimed more at blood pressure and calming than energy.

The active amounts are clear and the magnesium forms are complementary. The formula offers useful depth for metabolic magnesium but lacks direct alertness, fuel, or adaptogenic support.

Study evidence
Magnesium Supportive 4 studies
Stress Relief
Calm and Tension Relief
Stress Relief
Impact
High effect
B- Goal FitB+ Strength of SupportC CoverageB- Formula Quality
Magnesium · 250 mgGABA · 50 mg

Magnesium at 250 mg from glycinate, malate, and citrate provides a strong foundational relaxation component. Hawthorn and grape-seed extracts mainly target cardiovascular support, while GABA is only 50 mg.

The formula may suit tension that accompanies blood-pressure concerns, but it is not a broad stress formula. Hawthorn can add to the effects of blood-pressure or heart medicines, so users of those treatments need individualized medical guidance.

Study evidence
GABA Supportive 6 studies
Magnesium Supportive 13 studies
Digestive Health
Bowel Regularity
Digestive Health
Impact
High effect
C- Goal FitA- Strength of SupportF CoverageA Formula Quality
Magnesium · 250 mg

A meaningful magnesium amount may support stool regularity in people whose intake is low or who respond to magnesium's osmotic effect. Citrate, glycinate, and malate are clearly disclosed and avoid poorly absorbed oxide.

Hawthorn, grape seed, and GABA target blood pressure rather than digestion, so they add little gastrointestinal breadth. Its digestive value is situational rather than comprehensive.

Study evidence
Magnesium Supportive 50 studies

Ingredients

IngredientAmount per servingScore
Magnesium (Magnesium Citrate, Magnesium Glycinate, Magnesium Malate)
 250 mg 68
Hawthorn extract
600 mg 42
Grape seed extract
150 mg —
Gamma Amino Butyric Acid
50 mg —
Gluten Free Adults 18–50
Report overview
Magnesium (Magnesium Citrate, Magnesium Glycinate, Magnesium Malate) · 250 mg OverallScore68
C Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD Value

Glycinate and malate strengthen a blend that also includes moderately absorbed citrate. The elemental amount is clearly stated and fits the preferred range, but the added botanicals are not magnesium uptake cofactors. A high serving cost and lack of patented chelation keep the formula from leading on value.

View ingredientView products
Hawthorn · 600 mg OverallScore42
F Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyF Value

A substantial hawthorn extract amount supports the intended cardiovascular positioning. No active marker, plant part, or Latin species is supplied, so extract quality is only partly documented. The dose is clinically aligned, but the high serving cost weakens value.

View ingredientView products
Loading alternative details
84 Performance

Magnesium Bisglycinate Chelate

Healthy Origins

Its label clearly provides 200 mg of Magnesium as TRAACS Magnesium Bisglycinate Chelate, making it a more clearly defined magnesium option. Compared with the original, its ingredient and goal alignment is stronger, although it does not retain the original product’s hawthorn coverage.

83 Performance

Albion Chelated Magnesium Glycinate

Swanson Ultra

Its label clearly provides 400 mg of Magnesium as TRAACS Magnesium Bisglycinate Chelate, making it a more clearly defined magnesium option. Compared with the original, its ingredient and goal alignment is stronger, although it does not retain the original product’s hawthorn coverage.

84 Performance

Full Spectrum Hawthorn Extract

Planetary Herbals

Its label clearly provides 27 mg of Calcium, making it a more clearly defined hawthorn option. Compared with the original, its ingredient and goal alignment is stronger, although it does not retain the original product’s magnesium coverage.

80 Budget

Magnesium Caps 500 mg

Life Extension

Its label clearly provides 500 mg of Magnesium as Magnesium Citrate, preserving relevant magnesium coverage. Compared with the original, it lowers the serving cost, although it does not retain the original product’s hawthorn coverage.

85 Budget

Hawthorn 300 mg

Nature's Way

Its label clearly provides 300 mg of Hawthorn (leaf and flower) extract as Flavonoids, preserving relevant hawthorn coverage. Compared with the original, it lowers the serving cost, although it does not retain the original product’s magnesium coverage.

86 Budget

Hawthorn Extract 300 mg

NOW

Its label clearly provides 300 mg of Hawthorn extract as Vitexin-2”-O-Rhamnoside, preserving relevant hawthorn coverage. Compared with the original, it lowers the serving cost, although it does not retain the original product’s magnesium coverage.

85 Value

Magnesium Bisglycinate Chelate

Healthy Origins

Its label clearly provides 200 mg of Magnesium as TRAACS Magnesium Bisglycinate Chelate, keeping the formula relevant to magnesium. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although it does not retain the original product’s hawthorn coverage.

91 Value

Krebs Magnesium Potassium Complex

Nature's Way

Its label clearly provides 250 mg of Magnesium as Magnesium Lysinate, keeping the formula relevant to magnesium. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although it does not retain the original product’s hawthorn coverage.

88 Value

Magnesium Bisglycinate Powder

NOW

Its label clearly provides 250 mg of Magnesium as Magnesium Bisglycinate, keeping the formula relevant to magnesium. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although it does not retain the original product’s hawthorn coverage.

Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of long-term magnesium supplementation on endothelial function and cardiometabolic risk markers: A randomized controlled trial in overweight/obese adults.
    Joris PJ; Plat J; Bakker SJ; Mensink RP · Scientific reports · 2018
    Randomized trial52 participantsCardiovascular Support forMagnesium
  2. Effects of Hawthorn Fruit Extract Drink in Chinese Patients With Mild Hypertension and/or Hyperlipidaemia: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study.
    Zeng W; Chu TTW; Fok BSP; Ho WKK; Chan JCN; Tomlinson B · Dose-response : a publication of International Hormesis Society · 2024
    Randomized trial61 participantsCardiovascular Support forHawthorn
  3. Impact of oral magnesium supplementation on glycemic and cardiometabolic outcomes in prediabetic adults: a systematic review and meta-analysis.
    Basit A; Kumar S; Ahmed H; Babar R; Saeed SS; Siddiqui TA; Khan S; Saeed A; Khan M; Hanif H; Fasih A; Shabbir S; Kumar H; Kumar L; Raja A; Kumar S; Chander S · Journal of diabetes and metabolic disorders · 2026
    Meta-analysis384 participants5 studies pooledCardiovascular Support forMagnesium
  4. Hawthorn Herb Increases the Risk of Bleeding after Cardiac Surgery: An Evidence-Based Approach.
    Rababa'h AM; Altarabsheh SE; Haddad O; Deo SV; Obeidat Y; Al-Azzam S · The heart surgery forum · 2017
    Observational study116 participantsCardiovascular Support forHawthorn
  5. Serum magnesium and outcomes in heart failure with reduced ejection fraction: the GALACTIC-HF trial.
    Chimura M; Docherty KF; Jhund PS; Yang M; Ono R; Henderson AD; Metra M; Liu G; Divanji PH; Heitner SB; Kupfer S; Malik FI; Felker GM; Solomon SD; Teerlink JR; McMurray JJV · European heart journal · 2026
    Randomized trial6,147 participantsCardiovascular Support forMagnesium
  6. Promising hypotensive effect of hawthorn extract: a randomized double-blind pilot study of mild, essential hypertension.
    Walker AF; Marakis G; Morris AP; Robinson PA · Phytotherapy research : PTR · 2002
    Randomized trial36 participantsCardiovascular Support forHawthorn
  7. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  8. Real world effectiveness of Hawthorn special extract WS 1442 in a retrospective cohort study from Germany.
    Wyss C; Gündling PW; Kostev K · Scientific reports · 2024
    Cohort study9,100 participantsCardiovascular Support forHawthorn
  9. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  10. Hawthorn (Crataegus spp.) Clinically Significantly Reduces Blood Pressure in Hypertension: A Meta-Analysis of Randomized Placebo-Controlled Clinical Trials.
    Szikora Z; Mátyus RO; Szabó BV; Csupor D; Tóth B · Pharmaceuticals (Basel, Switzerland) · 2025
    Meta-analysis428 participants6 studies pooledCardiovascular Support Heart Health forHawthorn
  11. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  12. A randomised double blind placebo controlled clinical trial of a standardised extract of fresh Crataegus berries (Crataegisan) in the treatment of patients with congestive heart failure NYHA II.
    Degenring FH; Suter A; Weber M; Saller R · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2003
    Randomized trial143 participantsCardiovascular Support forHawthorn
  13. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  14. [Crataegus Special Extract WS 1442. Assessment of objective effectiveness in patients with heart failure (NYHA II)].
    Weikl A; Assmus KD; Neukum-Schmidt A; Schmitz J; Zapfe G; Noh HS; Siegrist J · Fortschritte der Medizin · 1996
    Randomized trial136 participantsCardiovascular Support forHawthorn
  15. Dose-response relationship between dietary magnesium intake and cardiovascular mortality: A systematic review and dose-based meta-regression analysis of prospective studies.
    Fang X; Liang C; Li M; Montgomery S; Fall K; Aaseth J; Cao Y · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2017
    Meta-analysis449,748 participants8 studies pooledCardiovascular Support forMagnesium
  16. Prospective, comparative cohort studies and their contribution to the benefit assessments of therapeutic options: heart failure treatment with and without Hawthorn special extract WS 1442.
    Habs M · Forschende Komplementarmedizin und klassische Naturheilkunde = Research in complementary and natural classical medicine · 2005
    Cohort study952 participantsCardiovascular Support forHawthorn
  17. The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis.
    Leenders NHJ; Vermeulen EA; van Ballegooijen AJ; Hoekstra T; de Vries R; Beulens JW; Vervloet MG · Clinical nutrition (Edinburgh, Scotland) · 2021
    Meta-analysis348,059 participants33 studies pooledCardiovascular Support forMagnesium
  18. Antihypertensive effect of Iranian Crataegus curvisepala Lind.: a randomized, double-blind study.
    Asgary S; Naderi GH; Sadeghi M; Kelishadi R; Amiri M · Drugs under experimental and clinical research · 2005
    Randomized trial92 participantsCardiovascular Support forHawthorn
  19. Effect of magnesium supplementation on endothelial function: A systematic review and meta-analysis of randomized controlled trials.
    Darooghegi Mofrad M; Djafarian K; Mozaffari H; Shab-Bidar S · Atherosclerosis · 2019
    Meta-analysis306 participants7 studies pooledCardiovascular Support forMagnesium
  20. Clinical efficacy of crataegus extract WS 1442 in congestive heart failure NYHA class II.
    Zapfe jun G · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2002
    Randomized trial40 participantsCardiovascular Support Heart Health forHawthorn
  21. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  22. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  23. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  24. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  25. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  26. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  27. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  28. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  29. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  30. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  31. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  32. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  33. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  34. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  35. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  36. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  37. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  38. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  39. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  40. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  41. [Actions of standardized extracts of Crataegus berries on exercise tolerance and quality of life in patients with congestive heart failure].
    Rietbrock N; Hamel M; Hempel B; Mitrovic V; Schmidt T; Wolf GK · Arzneimittel-Forschung · 2001
    Randomized trial88 participantsHeart Health forHawthorn
  42. Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials.
    Pittler MH; Schmidt K; Ernst E · The American journal of medicine · 2003
    Meta-analysis632 participants13 studies pooledHeart Health forHawthorn
  43. Baseline severity but not gender modulates quantified Crataegus extract effects in early heart failure--a pooled analysis of clinical trials.
    Eggeling T; Regitz-Zagrosek V; Zimmermann A; Burkart M · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
    Meta-analysis687 participants10 studies pooledHeart Health forHawthorn
  44. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  45. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  46. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  47. Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks.
    Yoto A; Murao S; Motoki M; Yokoyama Y; Horie N; Takeshima K; Masuda K; Kim M; Yokogoshi H · Amino acids · 2012
    Randomized trial63 participantsStress Relief forGABA
  48. GABA Supplementation, Increased Heart-Rate Variability, Emotional Response, Sleep Efficiency and Reduced Depression in Sedentary Overweight Women Undergoing Physical Exercise: Placebo-Controlled, Randomized Clinical Trial.
    Guimarães AP; Seidel H; Pires LVM; Trindade CO; Baleeiro RDS; Souza PM; Silva FGDE; Coelho DB; Becker LK; Oliveira EC · Journal of dietary supplements · 2024
    Randomized trial30 participantsStress Relief forGABA
  49. Relieving occupational fatigue by consumption of a beverage containing γ-amino butyric acid.
    Kanehira T; Nakamura Y; Nakamura K; Horie K; Horie N; Furugori K; Sauchi Y; Yokogoshi H · Journal of nutritional science and vitaminology · 2011
    Clinical trial30 participantsStress Relief forGABA
  50. Cortical gamma-aminobutyric acid and glutamate in posttraumatic stress disorder and their relationships to self-reported sleep quality.
    Meyerhoff DJ; Mon A; Metzler T; Neylan TC · Sleep · 2014
    Case-control study45 participantsStress Relief forGABA
  51. Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
    Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK · Journal of anaesthesiology, clinical pharmacology · 2025
    Randomized trial168 participantsStress Relief forGABA
  52. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  53. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  54. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  55. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  56. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  57. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  58. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  59. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  60. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  61. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium