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Glutathione 500 mg

NOW
4.6
★ ★ ★ ★ ★
(103178 ratings)
Glutathione 500 mg
Milk Thistle 100 mg
Product Image
Score78
A transparent 500 mg glutathione capsule with milk thistle, limited mainly by conventional delivery and smaller-pack value.
How scoring works
Quantity:30 Capsule(s) • (30 servings)
Goals:
Anti-Inflammatory Support

Score 78

A transparent 500 mg glutathione capsule with milk thistle, limited mainly by conventional delivery and smaller-pack value.
How scoring works

Also available as

2 options
120 servings Milk Thistle 100 mg, Glutathione 500 mg • 120 Capsule(s) • 120 servings $37.30 ($0.31 per serving) 60 servings Milk Thistle 100 mg, Glutathione 500 mg • 60 Capsule(s) • 60 servings $23.21 ($0.38 per serving)
$13.90($0.46 per serving)
Vitacost
$ 15.93
iHerb
$ 14.68
iHerb
$ 14.68
Daily Vita
$ 13.90
Amazon
$ 13.90
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Analysis

A single capsule provides 500 mg glutathione, 100 mg milk thistle extract, and 50 mg alpha-lipoic acid. The milk thistle is standardized to silymarin flavonoids.

All active amounts are disclosed, which makes the formula easy to assess. Glutathione is not described as liposomal or otherwise enhanced, so delivery is conventional.

The smaller bottle suits trial use but offers less routine value than larger versions. The formula supports antioxidant nutrition rather than acting as a direct anti-inflammatory treatment.

Who is it for
  • Adults trying oral glutathione
  • People seeking antioxidant support with milk thistle
Best for
  • Short-term trial use
  • Simple antioxidant routines

Pros

  • Substantial glutathione amount
  • Standardized milk thistle extract
  • Fully disclosed active formula

Cons

  • No enhanced glutathione delivery
  • Small bottle offers weaker value
  • Alpha-lipoic acid is modestly dosed

Warnings

  • Alpha-lipoic acid may add to glucose-lowering effects of insulin and diabetes medicines.

Nutrient quality

80 Highest impact

Glutathione is not identified as reduced or enhanced-delivery, and milk thistle lacks a standardization percentage. The glutathione amount is meaningful, while milk thistle and alpha-lipoic acid are supportive but modest.

Ingredient transparency

79 High impact

All three active ingredients have clear amounts. Excipients and daily directions are absent from the supplied data, which leaves some label details uncertain.

Customer satisfaction

71 High impact

The aggregate satisfaction average is favorable, though no detailed feedback is supplied. The very large volume makes the aggregate satisfaction signal stable.

Value for money

82 Highest impact

A meaningful core dose supports formula quality despite incomplete form details. The serving cost is acceptable but less efficient than larger package options.

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Goals

Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Highest effect
B+ Goal FitB- Strength of SupportB CoverageA Formula Quality
Glutathione · 500 mg

Glutathione directly supports antioxidant control, while milk thistle and alpha lipoic acid add complementary redox support. Human and mechanistic evidence supports glutathione-related oxidative balance, although oral benefit depends on formulation and absorption.

The 500 mg glutathione amount is meaningful, while milk thistle at 100 mg and alpha lipoic acid at 50 mg are supportive but modest. All amounts are disclosed, but the glutathione form and milk-thistle standardization are not specified.

Study evidence
Glutathione Disputed 2 studies

Ingredients

IngredientAmount per serving
Glutathione
500 mg
Milk Thistle extract (Silymarin Flavonoids)
 100 mg
Alpha Lipoic Acid
50 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
Glutathione · 500 mg OverallScore54
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value

The single capsule provides a substantial, clearly stated glutathione amount alongside milk thistle and alpha-lipoic acid. The absence of a reduced-form or enhanced-delivery claim leaves absorption potential uncertain. Its serving cost is near the collection benchmark and supports reasonable value.

View ingredientView products
Milk Thistle (Silymarin Flavonoids) · 100 mg OverallScore15
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

Silymarin flavonoids are named, yet the label data does not show a percentage or active yield. The dry capsule is convenient but lacks enhanced absorption and a stated source plant part. Value is limited because the serving cost exceeds the collection median while potency remains unclear.

View ingredientView products
Loading alternative details
80 Performance

Glutathione 500 mg

NOW
<p>Compared with the original, it retains Milk Thistle, and Glutathione and remains aligned with anti-inflammatory support. A substantial glutathione amount with milk thistle and alpha-lipoic acid creates a focused antioxidant formula at favorable value. The glutathione state and milk-thistle standardization are not specified, so absorption and supporting potency remain uncertain.</p>
82 Performance

Glutathione Reduced 500 mg

Jarrow Formulas
<p>Compared with the original, it retains Glutathione and remains aligned with anti-inflammatory support. A substantial reduced-glutathione amount provides strong antioxidant depth. Extensive customer evidence is mixed, while reasonable dose-adjusted value supports the formula.</p>
82 Performance

Reduced L-Glutathione 250 mg

Solgar
<p>Compared with the original, it retains Glutathione and remains aligned with anti-inflammatory support. A useful reduced-glutathione amount provides focused antioxidant support. Strong customer sentiment and reasonable serving economics support good value.</p>
85 Budget

Glutathione 500 mg

NOW
<p>It lowers recurring cost while retaining Milk Thistle, and Glutathione from the original's ingredient focus. Reduced glutathione is clearly identified at a substantial amount, with milk thistle and alpha-lipoic acid providing focused antioxidant support at strong value. Standard capsule delivery leaves some absorption uncertainty, and alpha-lipoic acid may add to glucose-lowering effects from insulin or diabetes medicines.</p>
84 Budget

L-Glutathione Reduced 500 mg

Healthy Origins
<p>It lowers recurring cost while retaining Glutathione from the original's ingredient focus. A substantial branded reduced-glutathione amount provides strong dose and source quality. Comparatively mixed customer sentiment contrasts with economical servings and excellent formula value.</p>
83 Budget

Glutathione Reduced 500 mg

Jarrow Formulas
<p>It lowers recurring cost while retaining Glutathione from the original's ingredient focus. A substantial reduced-glutathione amount provides strong antioxidant depth. Extensive customer evidence is mixed, while favorable serving economics support good value.</p>
84 Value

Milk Thistle

Kroeger Herb Products Co.
<p>It combines a lower recurring cost with Milk Thistle, supporting a practical value case against the original. A separate silymarin amount from milk thistle seed makes potency unusually easy to assess. Favorable serving value and a sizeable aggregate customer base strengthen the case.</p>
85 Value

Milk Thistle

Paradise
<p>It combines a lower recurring cost with Milk Thistle, supporting a practical value case against the original. A substantial stated silymarin amount provides focused milk thistle potency in a simple formula. Strong aggregate customer metrics and favorable serving value make it competitive among conventional options.</p>
82 Value

Glutathione 250 mg

NOW
<p>It combines a lower recurring cost with Glutathione, supporting a practical value case against the original. A meaningful glutathione amount provides focused antioxidant support at favorable serving value. Extensive customer evidence supports good practical value despite that limitation.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Serum type III procollagen, procollagen V, tumour necrosis factor-a, interleukin-6 in liver cirrhosis after antiviral treatment.
    Li W; Liu X; Bi F · Journal of medical biochemistry · 2025
    Randomized trial92 participantsAnti-Inflammatory Support forGlutathione
  2. Evaluation of the antioxidant and anti-inflammatory effect of sublingual glutathione on COPD patients.
    Farag A; Abass W; Qassem H · Journal of medicine and life · 2024
    Cohort study50 participantsAnti-Inflammatory Support forGlutathione