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L-Carnitine 500 mg

Solgar
4.5
★ ★ ★ ★ ★
(807 ratings)
L-Carnitine 1000 mg
Product Image
Score74
1,000 mg of L-carnitine of an unspecified form offers modest value, but missing form details weaken quality confidence.
How scoring works
Quantity:60 Tablet(s) • (30 servings)
Goals:
Cardiovascular Support
Fitness

Score 74

1,000 mg of L-carnitine of an unspecified form offers modest value, but missing form details weaken quality confidence.
How scoring works
$25.49($0.84 per serving)
iHerb
$ 25.49
Amazon
$ 26.99
Vitacost
$ 26.99
Pure Formulas
$ 26.99
Daily Vita
$ 26.99
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Analysis

The active amount is clearly disclosed and substantial enough to support a focused carnitine routine. The 1,000 mg serving is presented in a two-tablet serving format for routine use.

The chemical form, purity standard, and raw-material source are not stated, which prevents a confident comparison with researched forms. Benefits are most likely when carnitine support is relevant rather than as a universal performance or heart-health effect.

The formula stays focused on fatty-acid transport and cellular energy rather than broad cardiovascular or performance coverage. Modest value and 30 servings shape the practical appeal.

Who is it for
  • Adults seeking a simple carnitine supplement
  • Users seeking maintenance-level cellular-energy support
Best for
  • Focused fatty-acid transport support
  • Value-conscious carnitine use

Pros

  • Provides 1,000 mg per labeled serving
  • Simple carnitine-focused formula
  • Two-tablet serving format
  • Modest value

Cons

  • Chemical form is not disclosed
  • No branded raw-material source is identified
  • Supports a narrow metabolic pathway rather than broad cardiovascular coverage
  • Value is weaker than several comparable options

Warnings

  • L-carnitine at this amount may cause nausea, abdominal cramps, diarrhea, or a fishy body odor in sensitive users.
  • People treated for low thyroid function should seek medication-specific advice because L-carnitine may oppose some thyroid-hormone activity.
  • People with a seizure disorder should discuss high-dose L-carnitine with a clinician because increased seizure activity has been reported in susceptible users.

Nutrient quality

79 High impact

The listed carnitine amount is meaningful for cardiovascular and fitness support. The chemical form, source quality, and non-active ingredients are not supplied.

Ingredient transparency

76 High impact

Active complex amounts and serving details are stated clearly. The chemical form, source quality, and non-active ingredients are not supplied.

Customer satisfaction

69 High impact

The supplied average rating is strong, and a solid response volume provides reasonable confidence in the average rating. No comment-level feedback is supplied to judge recurring complaints or purpose-specific experiences.

Value for money

69 High impact

The useful dose offers moderate value but lacks premium sourcing detail. Formula focus and disclosure determine whether that value holds up in practice.

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Goals

Cardiovascular Support
Impact
High effect
B- Goal FitC+ Strength of SupportC- CoverageA+ Formula Quality
L-Carnitine · 1000 mg

A meaningful L-carnitine amount supports fatty-acid transport for heart-muscle energy production. The focused dose gives the product plausible depth in a cardiac-energy pathway.

The chemical form and source-quality details are not disclosed, which makes absorption and purity harder to assess. Evidence for broad cardiovascular marker improvement is also less consistent than for established omega-3 or magnesium uses.

Study evidence
L-Carnitine Supportive 73 studies
Fitness
Impact
Moderate effect
C- Goal FitC Strength of SupportD- CoverageA Formula Quality

L-carnitine may support recovery and fatty-acid transport, but its effects on exercise performance are usually modest and inconsistent. The disclosed amount reaches the lower edge of common supplemental use rather than a strong performance-oriented intake.

The single-ingredient label is transparent and keeps the purpose clear. Its narrow metabolic role leaves power, hydration, blood flow, and structural recovery needs uncovered.

Study evidence
L-Carnitine Supportive 52 studies

Ingredients

IngredientAmount per serving
L-Carnitine
1000 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Vegetarian
Report overview
L-Carnitine · 1000 mg OverallScore45
F Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyC Value

The disclosed amount reaches the preferred range for heart and fitness support. The missing chemical form and source-quality details make bioavailability and purity difficult to judge. Cost efficiency is moderate for the amount supplied.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Efficacy of l-carnitine supplementation for management of blood lipids: A systematic review and dose-response meta-analysis of randomized controlled trials.
    Askarpour M; Hadi A; Symonds ME; Miraghajani M; Omid Sadeghi; Sheikhi A; Ghaedi E · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2020
    Meta-analysis55 studies pooledCardiovascular Support forL-Carnitine
  2. Efficacy of a novel formulation of L-Carnitine, creatine, and leucine on lean body mass and functional muscle strength in healthy older adults: a randomized, double-blind placebo-controlled study.
    Evans M; Guthrie N; Pezzullo J; Sanli T; Fielding RA; Bellamine A · Nutrition & metabolism · 2020
    Randomized trial42 participantsFitness forL-Carnitine
  3. Blood Pressure and Metabolic Effects of Acetyl-l-Carnitine in Type 2 Diabetes: DIABASI Randomized Controlled Trial.
    Parvanova A; Trillini M; Podestà MA; Iliev IP; Aparicio C; Perna A; Peraro F; Rubis N; Gaspari F; Cannata A; Ferrari S; Bossi AC; Trevisan R; Parameswaran S; Chávez-Iñiguez JS; Masnic F; Seck SM; Jiamjariyaporn T; Cortinovis M; Perico L; Sharma K; Remuzzi G; Ruggenenti P; Warnock DG · Journal of the Endocrine Society · 2022
    Randomized trial229 participantsCardiovascular Support forL-Carnitine
  4. Acute L-Carnitine Supplementation Does Not Improve CrossFit® Performance: A Randomized, Double-Blind, Placebo-Controlled Crossover Study.
    Devrim-Lanpir A; Velasco LS; Ramirez Lara FG; Ojeda Sanchez A; Kimble R; Zare R; Gunes FE; Knechtle B; Weiss K; Rosemann T; Heinrich K · Nutrients · 2025
    Randomized trial20 participantsFitness forL-Carnitine
  5. Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
    Koeth RA; Wang Z; Levison BS; Buffa JA; Org E; Sheehy BT; Britt EB; Fu X; Wu Y; Li L; Smith JD; DiDonato JA; Chen J; Li H; Wu GD; Lewis JD; Warrier M; Brown JM; Krauss RM; Tang WH; Bushman FD; Lusis AJ; Hazen SL · Nature medicine · 2013
    Other2,595 participantsCardiovascular Support forL-Carnitine
  6. L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial.
    Malaguarnera M; Cammalleri L; Gargante MP; Vacante M; Colonna V; Motta M · The American journal of clinical nutrition · 2008
    Randomized trial66 participantsFitness forL-Carnitine
  7. The Effects of L-Carnitine Supplementation on Weight Loss, Glycemic Control, and Cardiovascular Risk Factors in Patients With Type 2 Diabetes: A Systematic Review and Dose-response Meta-Analysis of Randomized Controlled Trials.
    Mirrafiei A; Jayedi A; Shab-Bidar S · Clinical therapeutics · 2024
    Meta-analysis2,041 participants21 studies pooledCardiovascular Support forL-Carnitine
  8. A systematic review and meta-analysis of propionyl-L-carnitine effects on exercise performance in patients with claudication.
    Brass EP; Koster D; Hiatt WR; Amato A · Vascular medicine (London, England) · 2013
    Meta-analysis13 studies pooledFitness forL-Carnitine
  9. L-Carnitine supplementation reduces oxidized LDL cholesterol in patients with diabetes.
    Malaguarnera M; Vacante M; Avitabile T; Malaguarnera M; Cammalleri L; Motta M · The American journal of clinical nutrition · 2009
    Randomized trial81 participantsCardiovascular Support forL-Carnitine
  10. Oral acetyl-L-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study.
    Malaguarnera M; Vacante M; Giordano M; Pennisi G; Bella R; Rampello L; Malaguarnera M; Li Volti G; Galvano F · The American journal of clinical nutrition · 2011
    Randomized trial121 participantsFitness forL-Carnitine
  11. L-Carnitine's Effect on the Biomarkers of Metabolic Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Choi M; Park S; Lee M · Nutrients · 2021
    Meta-analysis9 studies pooledCardiovascular Support forL-Carnitine
  12. Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans.
    Wall BT; Stephens FB; Constantin-Teodosiu D; Marimuthu K; Macdonald IA; Greenhaff PL · The Journal of physiology · 2012
    Randomized trial14 participantsFitness forL-Carnitine
  13. Effective dosing of L-carnitine in the secondary prevention of cardiovascular disease: a systematic review and meta-analysis.
    Shang R; Sun Z; Li H · BMC cardiovascular disorders · 2015
    Meta-analysis3,108 participants5 studies pooledCardiovascular Support forL-Carnitine
  14. Effects of nine weeks L-Carnitine supplementation on exercise performance, anaerobic power, and exercise-induced oxidative stress in resistance-trained males.
    Koozehchian MS; Daneshfar A; Fallah E; Agha-Alinejad H; Samadi M; Kaviani M; Kaveh B M; Jung YP; Sablouei MH; Moradi N; Earnest CP; Chandler TJ; Kreider RB · Journal of exercise nutrition & biochemistry · 2020
    Randomized trial23 participantsFitness forL-Carnitine
  15. The Effects of L-Carnitine Supplementation on Serum Lipids: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Fathizadeh H; Milajerdi A; Reiner Ž; Kolahdooz F; Chamani M; Amirani E; Asemi Z · Current pharmaceutical design · 2020
    Meta-analysis67 studies pooledCardiovascular Support forL-Carnitine
  16. Propionyl-L-carnitine for intermittent claudication.
    Kamoen V; Vander Stichele R; Campens L; De Bacquer D; Van Bortel L; de Backer TL · The Cochrane database of systematic reviews · 2022
    Meta-analysis1,423 participants12 studies pooledFitness forL-Carnitine
  17. The Effects of L-Carnitine on Echocardiographic Changes in Patients With β-Thalassemia Major and Intermedia.
    Shahidi M; Hashemi SR; Fattahi N; Roshani D; Vahedi S; Sharifi P; Moradveisi B · Journal of pediatric hematology/oncology · 2020
    Randomized trial60 participantsCardiovascular Support forL-Carnitine
  18. Prolonged oral L-carnitine substitution increases bicycle ergometer performance in patients with severe, ischemically induced cardiac insufficiency.
    Löster H; Miehe K; Punzel M; Stiller O; Pankau H; Schauer J · Cardiovascular drugs and therapy · 2000
    Randomized trial41 participantsFitness forL-Carnitine
  19. Associations of circulating choline and its related metabolites with cardiometabolic biomarkers: an international pooled analysis.
    Pan XF; Yang JJ; Shu XO; Moore SC; Palmer ND; Guasch-Ferré M; Herrington DM; Harada S; Eliassen H; Wang TJ; Gerszten RE; Albanes D; Tzoulaki I; Karaman I; Elliott P; Zhu H; Wagenknecht LE; Zheng W; Cai H; Cai Q; Matthews CE; Menni C; Meyer KA; Lipworth LP; Ose J; Fornage M; Ulrich CM; Yu D · The American journal of clinical nutrition · 2021
    Meta-analysis32,853 participants17 studies pooledCardiovascular Support forL-Carnitine
  20. L-carnitine as an ergogenic aid for patients with chronic obstructive pulmonary disease submitted to whole-body and respiratory muscle training programs.
    Borghi-Silva A; Baldissera V; Sampaio LM; Pires-DiLorenzo VA; Jamami M; Demonte A; Marchini JS; Costa D · Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2007
    Randomized trial16 participantsFitness forL-Carnitine
  21. Efficacy and tolerability of combined treatment with L-carnitine and simvastatin in lowering lipoprotein(a) serum levels in patients with type 2 diabetes mellitus.
    Solfrizzi V; Capurso C; Colacicco AM; D'Introno A; Fontana C; Capurso SA; Torres F; Gadaleta AM; Koverech A; Capurso A; Panza F · Atherosclerosis · 2007
    Randomized trial52 participantsCardiovascular Support forL-Carnitine