Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
Randomized trial80 participantsflagEnergy forscienceMagnesium
- Exercise, magnesium and immune function.
Laires MJ; Monteiro C · Magnesium research · 2008
Narrative reviewflagEnergy forscienceMagnesium
- Minerals and Sarcopenia in Older Adults: An Updated Systematic Review.
van Dronkelaar C; Fultinga M; Hummel M; Kruizenga H; Weijs PJM; Tieland M · Journal of the American Medical Directors Association · 2023
Systematic review45 studies pooledflagFitness forscienceMagnesium
- The effect of magnesium supplementation on muscle fitness: a meta-analysis and systematic review.
Wang R; Chen C; Liu W; Zhou T; Xun P; He K; Chen P · Magnesium research · 2018
Meta-analysis542 participants14 studies pooledflagFitness forscienceMagnesium
- Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
Meta-analysis313,041 participants16 studies pooledflagCardiovascular Support forscienceMagnesium
- Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
Meta-analysis532,979 participants19 studies pooledflagCardiovascular Support forscienceMagnesium
- Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
Meta-analysis544,581 participants18 studies pooledflagCardiovascular Support forscienceMagnesium
- Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
Meta-analysisflagCardiovascular Support forscienceMagnesium
- Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
Meta-analysis200,934 participants20 studies pooledflagCardiovascular Support forscienceMagnesium
- The role of enzyme supplementation in digestive disorders.
Roxas M · Alternative medicine review : a journal of clinical therapeutic · 2009
Narrative reviewflagDigestive Health forscienceBromelain
- Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study.
Delgarm P; Mokhtare M; Ebrahimi Daryani N; Abolghasemi J; Rahideh ST · Scientific reports · 2025
Randomized trial70 participantsflagDigestive Health forscienceBromelain
- Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
Randomized trial100 participantsflagDigestive Health forscienceMagnesium
- Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
Randomized trial240 participantsflagDigestive Health forscienceMagnesium
- The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
Randomized trial286 participantsflagDigestive Health forscienceMagnesium
- A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
Randomized trial34 participantsflagDigestive Health forscienceMagnesium
- Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
Randomized trial240 participantsflagDigestive Health forscienceMagnesium
- Total magnesium intake and risk of frailty in older women.
Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
Cohort study81,524 participantsflagEnergy flagFitness forscienceMagnesium
- Red blood cell magnesium and chronic fatigue syndrome.
Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
Randomized trial32 participantsflagEnergy forscienceMagnesium
- Dietary Magnesium May Be Protective for Aging of Bone and Skeletal Muscle in Middle and Younger Older Age Men and Women: Cross-Sectional Findings from the UK Biobank Cohort.
Welch AA; Skinner J; Hickson M · Nutrients · 2018
Cross-sectional study156,575 participantsflagFitness forscienceMagnesium
- Dietary Magnesium Is Positively Associated With Skeletal Muscle Power and Indices of Muscle Mass and May Attenuate the Association Between Circulating C-Reactive Protein and Muscle Mass in Women.
Welch AA; Kelaiditi E; Jennings A; Steves CJ; Spector TD; MacGregor A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016
Cross-sectional study2,570 participantsflagFitness forscienceMagnesium
- Nutritional intake as a determinant of high-speed resistance and multicomponent training efficacy on strength in older women at risk of sarcopenia. A randomized clinical trial.
Polo-Ferrero L; Recio-Rodriguez JI; González-Manzano S; Martín-Vallejo J; Barbero-Iglesias FJ; Montero-Errasquín B; Cruz-Jentoft AJ; Méndez-Sánchez R · Clinical nutrition (Edinburgh, Scotland) · 2025
Randomized trial80 participantsflagFitness forscienceMagnesium
- Perioperative bromelain reduces pain and swelling and improves quality of life measures after mandibular third molar surgery: a randomized, double-blind, placebo-controlled clinical trial.
Majid OW; Al-Mashhadani BA · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons · 2014
Randomized trial45 participantsflagGeneral Health forscienceBromelain
- Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical trials.
Mendes ML; do Nascimento-Júnior EM; Reinheimer DM; Martins-Filho PR · Medicina oral, patologia oral y cirugia bucal · 2019
Meta-analysis6 studies pooledflagGeneral Health forscienceBromelain
- Bromelain-based enzymatic burn debridement: A systematic review of clinical studies on patient safety, efficacy and long-term outcomes.
Shoham Y; Gasteratos K; Singer AJ; Krieger Y; Silberstein E; Goverman J · International wound journal · 2023
Systematic review34 studies pooledflagGeneral Health forscienceBromelain
- Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain.
Müller S; März R; Schmolz M; Drewelow B; Eschmann K; Meiser P · Phytotherapy research : PTR · 2013
Randomized trial12 participantsflagGeneral Health forscienceBromelain
- Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adults.
Walker AF; Bundy R; Hicks SM; Middleton RW · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2003
Randomized trial77 participantsflagGeneral Health forscienceBromelain
- Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
Meta-analysis1,257 participants20 studies pooledflagGeneral Health forscienceMagnesium
- Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
Woods KL; Fletcher S · Lancet (London, England) · 1994
Randomized trial2,316 participantsflagGeneral Health forscienceMagnesium
- Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
Cohort study10,999 participantsflagGeneral Health forscienceMagnesium
- Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
Cohort study9,359 participantsflagGeneral Health forscienceMagnesium
- The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
Randomized trial64 participantsflagGeneral Health forscienceMagnesium
- Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
Randomized trial126 participantsflagStress Relief forscienceMagnesium
- Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
Randomized trial137 participantsflagStress Relief forscienceMagnesium
- Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
Non-randomized trial60 participantsflagStress Relief forscienceMagnesium
- Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
Randomized trial45 participantsflagStress Relief forscienceMagnesium
- Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
Randomized trialflagStress Relief forscienceMagnesium
- Magnesium and anabolic hormones in older men.
Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
Cohort study399 participantsflagTestosterone Support forscienceMagnesium
- Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
Cross-sectional study313 participantsflagTestosterone Support forscienceMagnesium
- Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
Randomized trial64 participantsflagTestosterone Support forscienceMagnesium
- The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
Meta-analysis1,600 participants25 studies pooledflagTestosterone Support forscienceMagnesium
- Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
Non-randomized trial20 participantsflagTestosterone Support forscienceMagnesium