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Double Strength Silymarin Milk Thistle Extract - 300 mg

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4.8
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(133867 ratings)
Milk Thistle 300 mg
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Score75
An affordable, coherent botanical blend is easy to use, though none of its extracts has verified active potency.
How scoring works
Quantity:100 Capsule(s) • (100 servings)
Goals:
Detoxification

Score 75

An affordable, coherent botanical blend is easy to use, though none of its extracts has verified active potency.
How scoring works

Also available as

2 options
200 servings Milk Thistle 300 mg • 200 Capsule(s) • 200 servings $25.04 ($0.12 per serving) 50 servings Milk Thistle 300 mg • 50 Capsule(s) • 50 servings $9.22 ($0.18 per serving)
$17.20($0.17 per serving)
iHerb
$ 18.36
Vitacost
$ 17.45
Vitacost
$ 17.45
Daily Vita
$ 17.40
Amazon
$ 17.20
iHerb
$ 18.36
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Analysis

A meaningful milk thistle amount anchors the formula, and the smaller dandelion and artichoke additions offer complementary digestive and bile-focused support. All ingredient weights are visible.

The label does not state a silymarin yield or active markers for either supporting herb. A basic dry capsule adds convenience without solving the potency or delivery uncertainty.

The product is affordable and reasonably focused for shoppers who want several botanicals together. A standardized single extract would be easier to assess for users who care mainly about milk thistle depth.

Who is it for
  • Adults seeking several liver-focused herbs together
  • Value-conscious capsule users
  • People comfortable with unstandardized extracts
Best for
  • Botanical breadth in one capsule
  • Routine liver and digestive support
  • Avoiding proprietary blends

Pros

  • All ingredient weights are disclosed
  • Milk thistle leads the formula
  • Good serving value

Cons

  • No silymarin yield
  • Artichoke and dandelion are modestly dosed
  • No absorption-support technology

Warnings

  • Milk thistle may cause nausea, gas, or loose stools in sensitive users.
  • People allergic to ragweed, daisies, or related plants may also react to milk thistle.
  • Milk thistle may affect blood-sugar control; people using insulin or glucose-lowering medicine should check with their prescriber.

Nutrient quality

68 High impact

Three complementary botanicals provide coherent liver and bile-support coverage. Missing active standardization makes the apparent dose depth uncertain.

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Ingredient transparency

78 High impact

Individual amounts and the absence of a hidden blend support clear dose disclosure. Vague botanical forms plus missing usage and excipient details reduce specificity.

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Customer satisfaction

73 High impact

The average rating is exceptionally strong, and the feedback volume supports confidence in it. No specific experience details are supplied to assess recurring complaints or purpose fit.

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Value for money

82 Highest impact

Affordable use and three relevant botanicals support good practical value. Unstandardized extracts keep quality-adjusted value below the top tier.

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Goals

Detoxification
Detoxification
Impact
High effect
B Goal FitD+ Strength of SupportC- CoverageB+ Formula Quality
Milk Thistle · 300 mg

Milk thistle directly supports hepatocyte protection, while dandelion and artichoke add a plausible biliary and digestive component. None of the extracts includes active standardization, so their functional potency remains uncertain.

The formula offers complementary liver and bile-focused coverage with moderate depth. Its concise design is coherent, though the smaller supporting botanicals may contribute less than their presence suggests.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Milk Thistle extract
300 mg
Dandelion
100 mg
Artichoke
50 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
Milk Thistle · 300 mg OverallScore23
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyC Value

The product provides a substantial extract amount but does not state silymarin concentration or active yield. A single dry capsule is convenient, while plant-part and absorption details are absent. The very low serving cost improves affordability, though potency remains uncertain.

View ingredientView products
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82 Performance

Super Milk Thistle

Nature's Way
Clearly disclosed silybin and silymarin give the milk-thistle component unusually strong active characterization. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the added licorice may be unsuitable for some users.
84 Performance

Milk Thistle

Nature's Answer
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
79 Performance

Milk Thistle (Silymarin)

Mason Natural
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
84 Budget

Milk Thistle

Kroeger Herb Products Co.
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. A lower serving cost improves routine value, although the formula remains focused rather than broad.
87 Budget

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
A clearly labeled total-silymarin extract provides focused and readily assessable milk-thistle activity. A lower serving cost improves routine value, although the formula remains focused rather than broad.
85 Budget

Milk Thistle

Paradise
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. A lower serving cost improves routine value, although the formula remains focused rather than broad.
79 Value

Milk Thistle

Solgar
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
82 Value

Milk Thistle Phytosome 300 mg

Swanson
A named milk-thistle phytosome provides a better-characterized absorption strategy than a basic, unstandardized herb amount. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
80 Value

Milk Thistle

Kirkman
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  2. Evaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial.
    Marjani M; Baghaei P; Kazempour Dizaji M; Gorji Bayani P; Fahimi F; Tabarsi P; Velayati AA · Iranian journal of pharmaceutical research : IJPR · 2016
    Randomized trial70 participantsDetoxification forMilk Thistle
  3. Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery.
    Mirhashemi SH; Hakakzadeh A; Yeganeh FE; Oshidari B; Rezaee SP · Metabolism open · 2022
    Observational studyDetoxification forMilk Thistle
  4. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  5. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  6. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  7. The hepatorenal protective effects of silymarin in cancer patients receiving chemotherapy: a randomized, placebo-controlled trial.
    Erfanian SS; Ansari H; Javanmard SH; Amini Z; Hajigholami A · BMC complementary medicine and therapies · 2024
    Randomized trial100 participantsDetoxification forMilk Thistle
  8. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury.
    Luangchosiri C; Thakkinstian A; Chitphuk S; Stitchantrakul W; Petraksa S; Sobhonslidsuk A · BMC complementary and alternative medicine · 2016
    Randomized trial55 participantsDetoxification forMilk Thistle
  9. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis.
    El-Kamary SS; Shardell MD; Abdel-Hamid M; Ismail S; El-Ateek M; Metwally M; Mikhail N; Hashem M; Mousa A; Aboul-Fotouh A; El-Kassas M; Esmat G; Strickland GT · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2009
    Randomized trial105 participantsDetoxification forMilk Thistle
  10. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  11. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle