Product Image

Double Strength Silymarin 300 mg

NOW
4.8
★ ★ ★ ★ ★
(133527 ratings)
Milk Thistle 300 mg
Product Image
Score78
Good value and coherent supporting herbs make this practical, though the actual silymarin dose remains undisclosed.
How scoring works
Quantity:50 Capsule(s) • (50 servings)
Goals:
Detoxification

Score 78

Good value and coherent supporting herbs make this practical, though the actual silymarin dose remains undisclosed.
How scoring works

Also available as

2 options
200 servings Milk Thistle 300 mg • 200 Capsule(s) • 200 servings $25.04 ($0.12 per serving) 100 servings Milk Thistle 300 mg • 100 Capsule(s) • 100 servings $17.20 ($0.17 per serving)
$9.22($0.18 per serving)
iHerb
$ 9.78
Pure Formulas
$ 9.22
Vitacost
$ 9.37
Daily Vita
$ 9.30
Vitacost
$ 9.47
Pure Formulas
$ 9.22
iHerb
$ 9.78
Amazon
$ 9.30
Report prices

Analysis

Milk thistle anchors the formula, with dandelion and artichoke adding complementary digestive and bile-related support. The ingredient combination makes sense for users who want more breadth than milk thistle alone.

The 300 mg extract is clearly listed as silymarin flavonoids, but no percentage or active yield is provided. Dandelion and artichoke appear in smaller amounts and may not provide deep standalone dosing.

Accessible value and a simple capsule format make regular use practical. The best fit is broad, economical botanical support rather than a precisely standardized high-potency silymarin product.

Who is it for
  • Value-focused supplement users
  • Adults seeking multi-herb liver support
Best for
  • Economical daily use
  • Combined liver and digestive support

Pros

  • Coherent three-herb formula
  • Clear ingredient weights
  • Accessible regular-use value

Cons

  • No quantified silymarin yield
  • Supporting herbs have modest amounts
  • No identified absorption support

Warnings

  • Dandelion and artichoke may stimulate bile flow; seek advice before use with gallstones or bile-duct obstruction.
  • Milk thistle, dandelion, and artichoke can trigger reactions in people sensitive to ragweed-family plants.
  • Dandelion may increase urination and can be a poor fit with prescription diuretics.

Nutrient quality

77 High impact

Silymarin flavonoids are named, while dandelion and artichoke fit the broader liver-digestive purpose. Missing standardization and modest supporting-herb doses limit dependable potency.

Ingredient transparency

77 High impact

Each botanical has a stated amount and no blend hides its dose. Milk-thistle standardization, daily-use directions, and non-active ingredients are missing.

Customer satisfaction

73 High impact

The supplied average rating is very strong and is supported by exceptionally large review count. No detailed feedback is available to assess repeated complaints or purpose-specific experiences.

Value for money

84 Highest impact

A coherent three-botanical formula and low qualitative serving cost provide good value. Missing silymarin potency remains the main limitation.

Report analysis

Goals

Detoxification
Detoxification
Impact
Moderate effect
B- Goal FitF Strength of SupportD+ CoverageB Formula Quality
Milk Thistle · 300 mg

Milk thistle provides the main liver-protective role, while dandelion and artichoke add biliary and digestive support. The combination is relevant to natural clearance but does not supply glutathione precursors or mineral cofactors.

All botanical weights are visible, yet the silymarin percentage and active amount are missing. A basic dry capsule and lightly dosed supporting herbs limit dependable pathway depth.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Milk Thistle extract (Silymarin Flavonoids)
 300 mg
Dandelion
100 mg
Artichoke
50 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
Milk Thistle (Silymarin Flavonoids) · 300 mg OverallScore9
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

The extract names silymarin flavonoids but does not disclose their percentage or the source plant part. A plain capsule offers no identified absorption support. The low cost cannot confirm value per active dose while potency is unknown.

View ingredientView products
Loading alternative details
82 Performance

Super Milk Thistle

Nature's Way
Clearly disclosed silybin and silymarin give the milk-thistle component unusually strong active characterization. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the added licorice may be unsuitable for some users.
84 Performance

Milk Thistle

Nature's Answer
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
79 Performance

Milk Thistle (Silymarin)

Mason Natural
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
84 Budget

Milk Thistle

Kroeger Herb Products Co.
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. A lower serving cost improves routine value, although the formula remains focused rather than broad.
87 Budget

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
A clearly labeled total-silymarin extract provides focused and readily assessable milk-thistle activity. A lower serving cost improves routine value, although the formula remains focused rather than broad.
85 Budget

Milk Thistle

Paradise
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. A lower serving cost improves routine value, although the formula remains focused rather than broad.
79 Value

Milk Thistle

Solgar
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
82 Value

Milk Thistle Phytosome 300 mg

Swanson
A named milk-thistle phytosome provides a better-characterized absorption strategy than a basic, unstandardized herb amount. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
80 Value

Milk Thistle

Kirkman
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  2. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  3. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  4. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury.
    Luangchosiri C; Thakkinstian A; Chitphuk S; Stitchantrakul W; Petraksa S; Sobhonslidsuk A · BMC complementary and alternative medicine · 2016
    Randomized trial55 participantsDetoxification forMilk Thistle
  5. Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery.
    Mirhashemi SH; Hakakzadeh A; Yeganeh FE; Oshidari B; Rezaee SP · Metabolism open · 2022
    Observational studyDetoxification forMilk Thistle
  6. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis.
    El-Kamary SS; Shardell MD; Abdel-Hamid M; Ismail S; El-Ateek M; Metwally M; Mikhail N; Hashem M; Mousa A; Aboul-Fotouh A; El-Kassas M; Esmat G; Strickland GT · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2009
    Randomized trial105 participantsDetoxification forMilk Thistle
  7. Evaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial.
    Marjani M; Baghaei P; Kazempour Dizaji M; Gorji Bayani P; Fahimi F; Tabarsi P; Velayati AA · Iranian journal of pharmaceutical research : IJPR · 2016
    Randomized trial70 participantsDetoxification forMilk Thistle
  8. The hepatorenal protective effects of silymarin in cancer patients receiving chemotherapy: a randomized, placebo-controlled trial.
    Erfanian SS; Ansari H; Javanmard SH; Amini Z; Hajigholami A · BMC complementary medicine and therapies · 2024
    Randomized trial100 participantsDetoxification forMilk Thistle
  9. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  10. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  11. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle