Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Differential cognitive effects of energy drink ingredients: caffeine, taurine, and glucose.
Giles GE; Mahoney CR; Brunyé TT; Gardony AL; Taylor HA; Kanarek RB · Pharmacology, biochemistry, and behavior · 2013
Randomized trial48 participantsflagEnergy forscienceCaffeine
- Caffeine administration at night during extended wakefulness effectively mitigates performance impairment but not subjective assessments of fatigue and sleepiness.
Paech GM; Banks S; Pajcin M; Grant C; Johnson K; Kamimori GH; Vedova CB · Pharmacology, biochemistry, and behavior · 2017
Randomized trial24 participantsflagEnergy forscienceCaffeine
- Activity of Choline Alphoscerate on Adult-Onset Cognitive Dysfunctions: A Systematic Review and Meta-Analysis.
Sagaro GG; Traini E; Amenta F · Journal of Alzheimer's disease : JAD · 2023
Meta-analysis8 studies pooledflagCognitive Support forscienceAlpha-GPC
- Effect of Choline Alfoscerate on the Progression From Mild Cognitive Impairment to Dementia: Distributed Network Analysis of a Multicenter Korean Database Using a Common Data Model.
Pyun JM; Lee I; Lee K; Kim MH; Park C; Yang HJ · Dementia and neurocognitive disorders · 2024
Cohort study3,062 participantsflagCognitive Support forscienceAlpha-GPC
- Green tea extract ingestion, fat oxidation, and glucose tolerance in healthy humans.
Venables MC; Hulston CJ; Cox HR; Jeukendrup AE · The American journal of clinical nutrition · 2008
Randomized trial23 participantsflagMetabolism Boost forscienceGreen Tea
- Effects of green tea or green tea extract on insulin sensitivity and glycaemic control in populations at risk of type 2 diabetes mellitus: a systematic review and meta-analysis of randomised controlled trials.
Wang X; Tian J; Jiang J; Li L; Ying X; Tian H; Nie M · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2015
Meta-analysis510 participants7 studies pooledflagMetabolism Boost forscienceGreen Tea
- Comparative study of choline alfoscerate as a combination therapy with donepezil: A mixed double-blind randomized controlled and open-label observation trial.
Lee W; Kim M · Medicine · 2024
Randomized trial119 participantsflagCognitive Support forscienceAlpha-GPC
- Effects of choline alfoscerate on cognitive function and quality of life in type 2 diabetes: A double-blind, randomized, placebo-controlled trial.
Sohn M; Park YH; Lim S · Diabetes, obesity & metabolism · 2025
Randomized trial36 participantsflagCognitive Support forscienceAlpha-GPC flagCognitive Support forscienceCholine
- [Gliatilin in the Treatment of Cognitive Impairments Not Reaching the Level of Dementia: Meta-Analysis and Systematic Review].
Voznyuk IA; Nepomnyashchiy IS; Kutkova AK; Tokareva DV; Prokhorova MV; Ovdiienko OA; Shusharina NN · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2025
Meta-analysis10 studies pooledflagCognitive Support forscienceAlpha-GPC
- Vertical Association Between Dietary Total Choline and L-alpha-glycerylphosphorylcholine and the Cognitive Function in Chinese Adults Aged over 55, Result from China Health and Nutrition Survey 1997-2018.
Guan F; Jia X; Huang F; Zhang J; Wei Y; Li L; Bai J; Wang H · Nutrients · 2024
Cohort study7,659 participantsflagCognitive Support forscienceAlpha-GPC
- Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial.
De Jesus Moreno Moreno M · Clinical therapeutics · 2003
Randomized trial261 participantsflagCognitive Support forscienceCholine
- Association of dietary choline intake with incidence of dementia, Alzheimer disease, and mild cognitive impairment: a large population-based prospective cohort study.
Niu YY; Yan HY; Zhong JF; Diao ZQ; Li J; Li CP; Chen LH; Huang WQ; Xu M; Xu ZT; Liang XF; Li ZH; Liu D · The American journal of clinical nutrition · 2025
Cohort study125,594 participantsflagCognitive Support forscienceCholine
- Choline intake during pregnancy and child cognition at age 7 years.
Boeke CE; Gillman MW; Hughes MD; Rifas-Shiman SL; Villamor E; Oken E · American journal of epidemiology · 2013
Cohort study895 participantsflagCognitive Support forscienceCholine
- Maternal choline supplementation mitigates alcohol exposure effects on neonatal brain volumes.
Warton FL; Molteno CD; Warton CMR; Wintermark P; Lindinger NM; Dodge NC; Zöllei L; van der Kouwe AJW; Carter RC; Jacobson JL; Jacobson SW; Meintjes EM · Alcoholism, clinical and experimental research · 2022
Randomized trial52 participantsflagCognitive Support forscienceCholine
- Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 trial.
de la Torre R; de Sola S; Hernandez G; Farré M; Pujol J; Rodriguez J; Espadaler JM; Langohr K; Cuenca-Royo A; Principe A; Xicota L; Janel N; Catuara-Solarz S; Sanchez-Benavides G; Bléhaut H; Dueñas-Espín I; Del Hoyo L; Benejam B; Blanco-Hinojo L; Videla S; Fitó M; Delabar JM; Dierssen M; TESDAD study group · The Lancet. Neurology · 2017
Randomized trial87 participantsflagCognitive Support forscienceGreen Tea
- Association between tea consumption and risk of cognitive disorders: A dose-response meta-analysis of observational studies.
Liu X; Du X; Han G; Gao W · Oncotarget · 2018
Meta-analysis48,435 participants17 studies pooledflagCognitive Support forscienceGreen Tea
- Investigating the Impact of Tea Consumption on Cognitive Function and Exploring Tea-Genetic Interactions in Older Adults Aged 65-105 Years: Findings from the 2002-2018 CLHLS Data.
Yu L; Yang M; Ye KX; Li C; Zou M; Wang J; Yuan X; Zheng D; Sun C; Zhang Y; Feng Q; Maier AB; Sun L; Feng L; Wang Y; Chen H; Zeng Y · The journal of prevention of Alzheimer's disease · 2024
Cohort study76,270 participantsflagCognitive Support forscienceGreen Tea
- Consumption of green tea, but not black tea or coffee, is associated with reduced risk of cognitive decline.
Noguchi-Shinohara M; Yuki S; Dohmoto C; Ikeda Y; Samuraki M; Iwasa K; Yokogawa M; Asai K; Komai K; Nakamura H; Yamada M · PloS one · 2014
Cohort study490 participantsflagCognitive Support forscienceGreen Tea
- Green Tea Consumption and the Risk of Incident Dementia in Elderly Japanese: The Ohsaki Cohort 2006 Study.
Tomata Y; Sugiyama K; Kaiho Y; Honkura K; Watanabe T; Zhang S; Sugawara Y; Tsuji I · The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2018
Cohort study13,645 participantsflagCognitive Support forscienceGreen Tea
- Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine.
Haskell CF; Kennedy DO; Wesnes KA; Scholey AB · Psychopharmacology · 2005
Randomized trial48 participantsflagEnergy forscienceCaffeine
- Caffeine-containing energy drink improves physical performance of elite rugby players during a simulated match.
Del Coso J; Ramírez JA; Muñoz G; Portillo J; Gonzalez-Millán C; Muñoz V; Barbero-Álvarez JC; Muñoz-Guerra J · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2016
Randomized trial26 participantsflagEnergy forscienceCaffeine
- Does Single or Combined Caffeine and Taurine Supplementation Improve Athletic and Cognitive Performance without Affecting Fatigue Level in Elite Boxers? A Double-Blind, Placebo-Controlled Study.
Ozan M; Buzdagli Y; Eyipinar CD; Baygutalp NK; Yüce N; Oget F; Kan E; Baygutalp F · Nutrients · 2022
Randomized trial20 participantsflagEnergy forscienceCaffeine
- Trait Energy and Fatigue Modify the Effects of Caffeine on Mood, Cognitive and Fine-Motor Task Performance: A Post-Hoc Study.
Fuller DT; Smith ML; Boolani A · Nutrients · 2021
Randomized trialflagEnergy forscienceCaffeine
- Effect of caffeine ingestion on cycling performance: a systematic review and meta-analysis.
Wu J; Xu K; Yin M; Ding X; Wang T; Zhang Q; Wu X; Xiao N · Frontiers in nutrition · 2026
Meta-analysis226 participants20 studies pooledflagFitness forscienceCaffeine
- Effects of Caffeine Intake on Endurance Running Performance and Time to Exhaustion: A Systematic Review and Meta-Analysis.
Wang Z; Qiu B; Gao J; Del Coso J · Nutrients · 2023
Meta-analysis254 participants21 studies pooledflagFitness forscienceCaffeine
- Acute Effects of Caffeine Supplementation on Movement Velocity in Resistance Exercise: A Systematic Review and Meta-analysis.
Raya-González J; Rendo-Urteaga T; Domínguez R; Castillo D; Rodríguez-Fernández A; Grgic J · Sports medicine (Auckland, N.Z.) · 2021
Meta-analysis12 studies pooledflagFitness forscienceCaffeine
- Sex Differences in the Ergogenic Response of Acute Caffeine Intake on Muscular Strength, Power and Endurance Performance in Resistance-Trained Individuals: A Randomized Controlled Trial.
Montalvo-Alonso JJ; Ferragut C; Del Val-Manzano M; Valadés D; Roberts J; Pérez-López A · Nutrients · 2024
Randomized trial76 participantsflagFitness forscienceCaffeine
- Can I Have My Coffee and Drink It? A Systematic Review and Meta-analysis to Determine Whether Habitual Caffeine Consumption Affects the Ergogenic Effect of Caffeine.
Carvalho A; Marticorena FM; Grecco BH; Barreto G; Saunders B · Sports medicine (Auckland, N.Z.) · 2022
Meta-analysis60 studies pooledflagFitness forscienceCaffeine
- Acute Alpha-Glycerylphosphorylcholine Supplementation Enhances Cognitive Performance in Healthy Men.
Kerksick CM · Nutrients · 2024
Randomized trial20 participantsflagMental Focus flagProductivity Boost forscienceAlpha-GPC
- Effects of modafinil and caffeine on night-time vigilance of air force crewmembers: A randomized controlled trial.
Wingelaar-Jagt YQ; Bottenheft C; Riedel WJ; Ramaekers JG · Journal of psychopharmacology (Oxford, England) · 2023
Randomized trial32 participantsflagMental Focus forscienceCaffeine
- Acute effects of caffeine on attention: a comparison of non-consumers and withdrawn consumers.
Smith AP; Christopher G; Sutherland D · Journal of psychopharmacology (Oxford, England) · 2013
Randomized trial70 participantsflagMental Focus forscienceCaffeine
- Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.
Wesensten NJ; Killgore WD; Balkin TJ · Journal of sleep research · 2006
Randomized trial48 participantsflagMental Focus forscienceCaffeine
- Effects of caffeine on mood and performance: a study of realistic consumption.
Brice CF; Smith AP · Psychopharmacology · 2003
Clinical trial24 participantsflagMental Focus forscienceCaffeine
- Effects of caffeine or diphenhydramine on visual vigilance.
Fine BJ; Kobrick JL; Lieberman HR; Marlowe B; Riley RH; Tharion WJ · Psychopharmacology · 1995
Randomized trial24 participantsflagMental Focus forscienceCaffeine
- Four-year follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder.
Wozniak JR; Fink BA; Fuglestad AJ; Eckerle JK; Boys CJ; Sandness KE; Radke JP; Miller NC; Lindgren C; Brearley AM; Zeisel SH; Georgieff MK · Journal of neurodevelopmental disorders · 2021
Randomized trial31 participantsflagMental Focus forscienceCholine
- The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort.
Poly C; Massaro JM; Seshadri S; Wolf PA; Cho E; Krall E; Jacques PF; Au R · The American journal of clinical nutrition · 2012
Cohort study1,391 participantsflagMental Focus forscienceCholine
- Association between Maternal Choline, Fetal Brain Development, and Child Neurocognition: Systematic Review and Meta-Analysis of Human Studies.
Obeid R; Derbyshire E; Schön C · Advances in nutrition (Bethesda, Md.) · 2022
Meta-analysis30 studies pooledflagMental Focus forscienceCholine
- Effect of Choline Supplementation on Neurological, Cognitive, and Behavioral Outcomes in Offspring Arising from Alcohol Exposure During Development: A Quantitative Systematic Review of Clinical and Preclinical Studies.
Akison LK; Kuo J; Reid N; Boyd RN; Moritz KM · Alcoholism, clinical and experimental research · 2019
Systematic reviewflagMental Focus forscienceCholine
- Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk.
Ross RG; Hunter SK; McCarthy L; Beuler J; Hutchison AK; Wagner BD; Leonard S; Stevens KE; Freedman R · The American journal of psychiatry · 2013
Randomized trialflagMental Focus forscienceCholine
- A Randomized Study to Examine the Ability of a Caffeine-Based Energy Drink to Impact Energy Expenditure, Fat Oxidation, and Cognitive Performance.
Krieger J; Schrautemeier A; Hagele A; Gaige C; Mennemeyer O; Tolbert S; Iannotti J; Kerksick C; Noonan C; Mumford P · Nutrients · 2025
Randomized trial60 participantsflagMetabolism Boost forscienceCaffeine
- Oolong tea increases metabolic rate and fat oxidation in men.
Rumpler W; Seale J; Clevidence B; Judd J; Wiley E; Yamamoto S; Komatsu T; Sawaki T; Ishikura Y; Hosoda K · The Journal of nutrition · 2001
Randomized trial12 participantsflagMetabolism Boost forscienceCaffeine
- Effect of caffeine intake on fat oxidation rate during exercise: is there a dose-response effect?
Gutiérrez-Hellín J; Aguilar-Navarro M; Ruiz-Moreno C; Muñoz A; Varillas-Delgado D; Amaro-Gahete FJ; Del Coso J · European journal of nutrition · 2023
Randomized trial18 participantsflagMetabolism Boost forscienceCaffeine
- Comparison of changes in energy expenditure and body temperatures after caffeine consumption.
Koot P; Deurenberg P · Annals of nutrition & metabolism · 1995
Randomized trial12 participantsflagMetabolism Boost forscienceCaffeine
- Caffeine Increases Work Done above Critical Power, but Not Anaerobic Work.
Silveira R; Andrade-Souza VA; Arcoverde L; Tomazini F; Sansonio A; Bishop DJ; Bertuzzi R; Lima-Silva AE · Medicine and science in sports and exercise · 2018
Randomized trial9 participantsflagMetabolism Boost forscienceCaffeine
- Effect of green tea on glucose control and insulin sensitivity: a meta-analysis of 17 randomized controlled trials.
Liu K; Zhou R; Wang B; Chen K; Shi LY; Zhu JD; Mi MT · The American journal of clinical nutrition · 2013
Meta-analysis1,133 participants17 studies pooledflagMetabolism Boost forscienceGreen Tea
- Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans.
Dulloo AG; Duret C; Rohrer D; Girardier L; Mensi N; Fathi M; Chantre P; Vandermander J · The American journal of clinical nutrition · 1999
Randomized trial10 participantsflagMetabolism Boost forscienceGreen Tea
- A 60-Day Green Tea Extract Supplementation Counteracts the Dysfunction of Adipose Tissue in Overweight Post-Menopausal and Class I Obese Women.
Rondanelli M; Gasparri C; Perna S; Petrangolini G; Allegrini P; Fazia T; Bernardinelli L; Cavioni A; Mansueto F; Oberto L; Patelli Z; Tartara A; Riva A · Nutrients · 2022
Randomized trial28 participantsflagMetabolism Boost forscienceGreen Tea
- Epigallocatechin gallate alleviates non-alcoholic fatty liver disease through the inhibition of the expression and activity of Dipeptide kinase 4.
Yang M; Yan R; Sha R; Wang X; Zhou S; Li B; Zheng Q; Cao Y · Clinical nutrition (Edinburgh, Scotland) · 2024
Randomized trialflagMetabolism Boost forscienceGreen Tea
- Treatment of dementia with neurotransmission modulation.
Doggrell SA; Evans S · Expert opinion on investigational drugs · 2004
Narrative reviewflagProductivity Boost forscienceAlpha-GPC
- Effects of caffeine on alertness.
Zwyghuizen-Doorenbos A; Roehrs TA; Lipschutz L; Timms V; Roth T · Psychopharmacology · 1990
Randomized trial24 participantsflagProductivity Boost forscienceCaffeine
- Effects of Different Sources of Low-Dose Caffeine on Mood/Arousal and Cognitive Performance.
Irwin C; McCartney D; Grant G; Delang N; Bartrim K; Cox GR; Desbrow B · Perceptual and motor skills · 2023
Randomized trial22 participantsflagProductivity Boost forscienceCaffeine
- Effects of caffeine, sleep loss, and stress on cognitive performance and mood during U.S. Navy SEAL training. Sea-Air-Land.
Lieberman HR; Tharion WJ; Shukitt-Hale B; Speckman KL; Tulley R · Psychopharmacology · 2003
Randomized trial68 participantsflagProductivity Boost forscienceCaffeine
- A review of caffeine's effects on cognitive, physical and occupational performance.
McLellan TM; Caldwell JA; Lieberman HR · Neuroscience and biobehavioral reviews · 2017
Narrative reviewflagProductivity Boost forscienceCaffeine
- Acute caffeine supplementation as a nutrition-based strategy to mitigate sleep-loss-related cognitive and operational performance impairments in military personnel: a systematic review and meta-analysis.
Wang R; Wang W; Meng L; Hao G; Gu G · Frontiers in nutrition · 2026
Meta-analysis7 studies pooledflagProductivity Boost forscienceCaffeine
- Changes in caffeine intake and long-term weight change in men and women.
Lopez-Garcia E; van Dam RM; Rajpathak S; Willett WC; Manson JE; Hu FB · The American journal of clinical nutrition · 2006
Cohort study58,157 participantsflagWeight Loss forscienceCaffeine
- Does caffeine ingestion before a short-term sprint interval training promote body fat loss?
Ferreira GA; Felippe LC; Bertuzzi R; Bishop DJ; Ramos IS; De-Oliveira FR; Lima-Silva AE · Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2020
Randomized trial20 participantsflagWeight Loss forscienceCaffeine
- Eight Weeks of Sprint Interval Training With Adding Caffeine Ingestion Leads to Greater Improvements in Health-Related Physiological Parameters in Obese Male Adults.
Zhiang J; Song Q · Physiological research · 2026
Randomized trial30 participantsflagWeight Loss forscienceCaffeine
- Caffeine treatment prevented from weight regain after calorie shifting diet induced weight loss.
Davoodi SH; Hajimiresmaiel SJ; Ajami M; Mohseni-Bandpei A; Ayatollahi SA; Dowlatshahi K; Javedan G; Pazoki-Toroudi H · Iranian journal of pharmaceutical research : IJPR · 2014
Non-randomized trial60 participantsflagWeight Loss forscienceCaffeine
- The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials.
Tabrizi R; Saneei P; Lankarani KB; Akbari M; Kolahdooz F; Esmaillzadeh A; Nadi-Ravandi S; Mazoochi M; Asemi Z · Critical reviews in food science and nutrition · 2020
Meta-analysis606 participants13 studies pooledflagWeight Loss forscienceCaffeine
- A green tea extract high in catechins reduces body fat and cardiovascular risks in humans.
Nagao T; Hase T; Tokimitsu I · Obesity (Silver Spring, Md.) · 2007
Randomized trial240 participantsflagWeight Loss forscienceGreen Tea
- Green tea beverages enriched with catechins with a galloyl moiety reduce body fat in moderately obese adults: a randomized double-blind placebo-controlled trial.
Kobayashi M; Kawano T; Ukawa Y; Sagesaka YM; Fukuhara I · Food & function · 2016
Randomized trial126 participantsflagWeight Loss forscienceGreen Tea
- Green tea catechin consumption enhances exercise-induced abdominal fat loss in overweight and obese adults.
Maki KC; Reeves MS; Farmer M; Yasunaga K; Matsuo N; Katsuragi Y; Komikado M; Tokimitsu I; Wilder D; Jones F; Blumberg JB; Cartwright Y · The Journal of nutrition · 2009
Randomized trial132 participantsflagWeight Loss forscienceGreen Tea
- Effect of Decaffeinated Green Tea Polyphenols on Body Fat and Precocious Puberty in Obese Girls: A Randomized Controlled Trial.
Xie L; Tang Q; Yao D; Gu Q; Zheng H; Wang X; Yu Z; Shen X · Frontiers in endocrinology · 2022
Randomized trial62 participantsflagWeight Loss forscienceGreen Tea
- Effectiveness of green tea on weight reduction in obese Thais: A randomized, controlled trial.
Auvichayapat P; Prapochanung M; Tunkamnerdthai O; Sripanidkulchai BO; Auvichayapat N; Thinkhamrop B; Kunhasura S; Wongpratoom S; Sinawat S; Hongprapas P · Physiology & behavior · 2008
Randomized trial60 participantsflagWeight Loss forscienceGreen Tea