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Thyrosol

Metagenics
4.7
★ ★ ★ ★ ★
(72 ratings)
Rhodiola
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Score74
A coherent thyroid-oriented nutrient blend with supportive rhodiola and myo-inositol. Modest adaptogen dosing and thyroid-specific cautions make it a targeted product.
How scoring works
Quantity:90 Capsule(s) • (90 servings)
Goals:
Energy
Cognitive Support
Mental Focus

Score 74

A coherent thyroid-oriented nutrient blend with supportive rhodiola and myo-inositol. Modest adaptogen dosing and thyroid-specific cautions make it a targeted product.
How scoring works
$49.95($0.55 per serving)
iHerb
$ 49.95
Pure Formulas
$ 49.95
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Analysis

Rhodiola rosea extract at 133 mg and myo-inositol at 200 mg anchor the formula, with iodine, selenium, zinc, vitamin D, vitamin E, and several supporting nutrients. The design is more clearly aimed at thyroid-related nutritional support than direct cognitive stimulation.

Rosavins and salidroside are named, but their percentages and relationship to total extract are not shown. Most mineral forms are specific and useful, though magnesium is too low to provide meaningful standalone support.

One capsule is convenient for users who intentionally want this thyroid-and-adaptogen combination. People seeking focused rhodiola can obtain a larger, better-standardized amount at lower cost, while people with thyroid disease need individualized supervision.

Who is it for
  • Adults seeking a thyroid-oriented nutrient formula
  • People wanting modest rhodiola within a micronutrient blend
Best for
  • Thyroid-related nutrient support
  • Stress-related energy
  • Combined myo-inositol and trace-mineral intake

Pros

  • Uses specific vitamin and mineral forms
  • Names rosavins and salidroside
  • Includes myo-inositol, iodine, and selenium
  • One-capsule serving

Cons

  • Rhodiola marker percentages are missing
  • Rhodiola amount is modest for focused use
  • Magnesium amount is small
  • Only fair value

Warnings

  • Iodine can alter thyroid management, so people with thyroid disease or thyroid medication should use the formula only with clinician guidance.
  • Preformed vitamin A should be counted alongside prenatal products or other high-vitamin-A supplements during pregnancy.
  • Rhodiola may interact with antidepressants or other serotonergic medicines, so those combinations need prescriber guidance.

Nutrient quality

82 Highest impact

Vitamin D3, natural vitamin E, citrate minerals, selenomethionine, and standardized rhodiola are well-chosen forms. The core herbal ingredients are supplied at practical amounts, though potency depends on extract quality.

Ingredient transparency

76 High impact

Specific quantities are listed for all active nutrients and rhodiola. No proprietary blend hides a key dose.

Customer satisfaction

60 Moderate impact

The supplied aggregate rating indicates very favorable satisfaction, though no experience details are provided. The limited response count leaves considerable uncertainty around satisfaction.

Value for money

75 High impact

Formula quality is reasonable for the cost, with some limitations. The serving cost is reasonable for the disclosed actives.

Report analysis

Goals

Energy
Energy
Impact
High effect
B+ Goal FitB- Strength of SupportB- CoverageA Formula Quality
Iodine · 50 mcgVitamin D · 8.3 mcgMagnesium · 33 mgRiboflavin · 2 mg

Rhodiola rosea and iodine address stress-related fatigue and thyroid-dependent metabolic rate, giving the formula two relevant energy pathways. Myo-inositol and supporting micronutrients fit the thyroid-oriented design, though most are supplied at modest amounts.

Rhodiola marker names are provided, but their percentages and balance are missing, so extract strength remains uncertain. The rhodiola amount is supportive rather than robust, and iodine, magnesium, riboflavin, and other nutrients are not developed as high-potency energy actives.

Study evidence
Iodine Adverse 3 studies
Magnesium Supportive 4 studies
Rhodiola Supportive 18 studies
Riboflavin Mixed 6 studies
Cognitive Support
Cognitive Support
Impact
Moderate effect
C+ Goal FitC+ Strength of SupportD+ CoverageB- Formula Quality
Magnesium · 33 mgVitamin D · 8.3 mcg

Rhodiola provides direct support for stress-related fatigue, while iodine and selenium support thyroid-linked energy. The extract names rosavins and salidroside.

Marker percentages are missing and the rhodiola amount is modest for focused cognitive use. Most nutrients serve thyroid support rather than memory, attention, or processing speed.

Study evidence
Rhodiola Supportive 7 studies
Mental Focus
Mental Focus
Impact
Moderate effect
C- Goal FitC- Strength of SupportC- CoverageC- Formula Quality
Vitamin D · 8.3 mcgMagnesium · 33 mg

Rhodiola may help mental stamina under stress, while iodine, selenium, and other nutrients mainly support thyroid function. The formula has a weaker direct focus rationale than a dedicated Rhodiola or stimulant product.

Rosavin and salidroside are named, but marker percentages are missing and the extract amount is modest. Users with thyroid disease or thyroid medication should be cautious because the iodine-containing formula is designed around thyroid support.

Study evidence
Iodine No effect 17 studies
Rhodiola Supportive 15 studies

Ingredients

IngredientAmount per serving
Vitamin A (Retinyl Palmitate)
 300 mcg
Vitamin D (Cholecalciferol)
 8.3 mcg
Vitamin E (D-Alpha-Tocopheryl Succinate)
 44.7 mg
Riboflavin
2 mg
Niacin (Niacinamide)
 3 mg
Iodine (Potassium Iodide)
 50 mcg
Magnesium (Magnesium Citrate)
 33 mg
Zinc (Zinc Citrate)
 6.7 mg
Selenium (Selenomethionine)
 50 mcg
Myo-Inositol
200 mg
Rhodiola (Rhodiola rosea L.) rhizome extract (Rosavins, Salidroside)
 133 mg
Gluten Free Adults 18–50 Women
Report overview
Rhodiola (Rosavins, Salidroside) · 133 mg OverallScore70
A- Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

Rhodiola rosea extract identifies both rosavins and salidroside, which supports a relevant active profile. Marker percentages are missing, so the preferred natural balance cannot be confirmed. The serving is modest and works better as part of a blend than as a focused Rhodiola dose.

View ingredientView products
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81 Performance

Super Rhodiola Root Extract 500 mg

Solaray
<p>A high-strength standardized rhodiola extract provides a focused formula for energy, focus, and stress support. Compared with the original, its focused rhodiola profile and stronger ingredient specification make it a more dependable choice for energy, focus, and stress support. Strong aggregate satisfaction and clear dosing support good value, although lower-cost close alternatives exist.</p>
83 Performance

Rhodiola Extract 500 mg

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<p>A substantial root-extract amount with both marker groups supports consistent focused use. Compared with the original, its focused rhodiola profile and stronger ingredient specification make it a more dependable choice for energy, focus, and stress support. The exact species and marker percentages are not fully stated in the supplied ingredient line, while the dose may feel stimulating for some users.</p>
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Rhodiola Rosea 500 mg

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<p>A high-strength standardized rhodiola extract offers a focused formula with strong aggregate satisfaction. Compared with the original, its focused rhodiola profile and stronger ingredient specification make it a more dependable choice for energy, focus, and stress support. The serving cost is higher than several close alternatives, but clear dosing and a long supply preserve solid value.</p>
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Rhodiola Rosea Root 400 mg

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<p>A simple rhodiola root dose offers a focused formula and exceptional serving value. Compared with the original, it lowers recurring cost while keeping rhodiola central to the formula. Lack of standardization leaves the active rosavin and salidroside content uncertain despite strong aggregate satisfaction.</p>
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Rhodiola 100 mg

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<p>A standardized rhodiola extract provides a simple, clearly targeted option, although the amount is modest. Compared with the original, it lowers recurring cost while keeping rhodiola central to the formula. Strong aggregate satisfaction and a very low serving cost make it an appealing value for users seeking a lighter dose.</p>
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Rhodiola 250 mg

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<p>A standardized rhodiola extract offers a sensible middle-strength option for energy, focus, and stress support. Compared with the original, it lowers recurring cost while keeping rhodiola central to the formula. Strong aggregate satisfaction, clear dosing, and a low serving cost support excellent value.</p>
79 Value

Rhodiola Schizandra 500 mg

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<p>Standardized rhodiola and schisandra form a coherent adaptogenic blend for energy and stress support. Compared with the original, it offers a more favorable balance of rhodiola quality, label clarity, and recurring cost. Strong aggregate satisfaction supports confidence, while the serving cost is somewhat higher than focused rhodiola-only options.</p>
82 Value

Rhodiola 500 mg

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<p>A high-strength standardized rhodiola extract is well aligned with energy, focus, and stress support. Compared with the original, it offers a more favorable balance of rhodiola quality, label clarity, and recurring cost. The larger supply combines strong aggregate satisfaction with excellent serving value.</p>
80 Value

Full Spectrum Rhodiola Rosea Extract 327 mg

Planetary Herbals
<p>A substantial Rhodiola rosea extract names both key marker groups and fits focused adaptogen use. Compared with the original, it offers a more favorable balance of rhodiola quality, label clarity, and recurring cost. Marker percentages are missing, and the high amount may feel stimulating for sensitive users.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.
    Darbinyan V; Kteyan A; Panossian A; Gabrielian E; Wikman G; Wagner H · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2001
    Randomized trial56 participantsCognitive Support forRhodiola
  2. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity.
    Panossian A; Wikman G · Current clinical pharmacology · 2009
    Narrative reviewCognitive Support Mental Focus forRhodiola
  3. Effects of a Rhodiola rosea extract on mental resource allocation and attention: An event-related potential dual task study.
    Koop T; Dienel A; Heldmann M; Münte TF · Phytotherapy research : PTR · 2021
    Single-arm trial50 participantsCognitive Support forRhodiola
  4. Central additive effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy.
    Al-Kuraishy HM · Journal of intercultural ethnopharmacology · 2016
    Clinical trial112 participantsCognitive Support forRhodiola
  5. Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes.
    Łuszczak J; Kocki J · Annals of agricultural and environmental medicine : AAEM · 2026
    Systematic review19 studies pooledCognitive Support forRhodiola
  6. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.
    Olsson EM; von Schéele B; Panossian AG · Planta medica · 2009
    Randomized trial60 participantsCognitive Support forRhodiola
  7. Association of radioactive iodine treatment with survivorship symptoms and primary care utilisation in women of reproductive age with thyroid cancer: a retrospective cohort study.
    Devanarayan P; Hartman M; Partin M · Family medicine and community health · 2026
    Cohort study10,882 participantsEnergy forIodine
  8. Energy level and fatigue after surgery for thyroid cancer: A population-based study of patient-reported outcomes.
    Hughes DT; Reyes-Gastelum D; Kovatch KJ; Hamilton AS; Ward KC; Haymart MR · Surgery · 2020
    Cohort study2,584 participantsEnergy forIodine
  9. Health-Related Quality of Life in Differentiated Thyroid Cancer Survivors: A Cross-Sectional Study From Turkey.
    Gültekin A; Kahraman MY; Şengöz T; Şimşek FS · Head & neck · 2026
    Cross-sectional study202 participantsEnergy forIodine
  10. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  11. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  12. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  13. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  14. The Effect of Short-Term Rhodiola rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players.
    Wang J; Zhao H; Yu L; Zhao K; Jiang W; Liu S; Dai J; Xu L; Sun P; Yun H; Liu C · Nutrients · 2025
    Randomized trial48 participantsEnergy forRhodiola
  15. Effects of Rhodiola rosea on Physical and Decision-Making Performance in Football Players: A Randomised Controlled Trial.
    Dou Y; Wang Y; Zhang W; Jiang Y; Zhang J; Yang T; Han Z; Li Y; Liu C; Ren D · Nutrients · 2026
    Randomized trial24 participantsEnergy Mental Focus forRhodiola
  16. Combined Effects of Rhodiola Rosea and Caffeine Supplementation on Straight Punch Explosive Power in Untrained and Trained Boxing Volunteers: A Synergistic Approach.
    Tao B; Sun H; Li H; Xu Z; Xu Y; Chen L; Ma C; Zhang X; Yu L; Bao S; Liu C · Metabolites · 2025
    Randomized trial96 participantsEnergy forRhodiola
  17. Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial.
    Lekomtseva Y; Zhukova I; Wacker A · Complementary medicine research · 2019
    Single-arm trial100 participantsEnergy forRhodiola
  18. Combined Rhodiola rosea and eccentric training boost endurance performance and lower-limb reactive strength in recreationally active women.
    Wang IL; Su Y; Zhang L; Tang M; Chen YM · Frontiers in physiology · 2025
    Randomized trial30 participantsEnergy forRhodiola
  19. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  20. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  21. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  22. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  23. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy forRiboflavin
  24. Iodine supplementation improves cognition in iodine-deficient schoolchildren in Albania: a randomized, controlled, double-blind study.
    Zimmermann MB; Connolly K; Bozo M; Bridson J; Rohner F; Grimci L · The American journal of clinical nutrition · 2006
    Randomized trial310 participantsMental Focus forIodine
  25. Iodine intake from supplements and diet during pregnancy and child cognitive and motor development: the INMA Mother and Child Cohort Study.
    Murcia M; Espada M; Julvez J; Llop S; Lopez-Espinosa MJ; Vioque J; Basterrechea M; Riaño I; González L; Alvarez-Pedrerol M; Tardón A; Ibarluzea J; Rebagliato M · Journal of epidemiology and community health · 2019
    Cohort study1,803 participantsMental Focus forIodine
  26. Breastfeeding and maternal and infant iodine nutrition.
    Azizi F; Smyth P · Clinical endocrinology · 2009
    Systematic review36 studies pooledMental Focus forIodine
  27. Preconception Maternal Iodine Status Is Positively Associated with IQ but Not with Measures of Executive Function in Childhood.
    Robinson SM; Crozier SR; Miles EA; Gale CR; Calder PC; Cooper C; Inskip HM; Godfrey KM · The Journal of nutrition · 2019
    Cohort study654 participantsMental Focus forIodine
  28. Iodine deficiency: consequences and progress toward elimination.
    Maberly GF; Haxton DP; van der Haar F · Food and nutrition bulletin · 2006
    Narrative reviewMental Focus forIodine
  29. The effectiveness and efficacy of Rhodiola rosea L.: a systematic review of randomized clinical trials.
    Hung SK; Perry R; Ernst E · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
    Systematic review11 studies pooledMental Focus forRhodiola
  30. Dose-Response Effects of Short-Term Rhodiola rosea (Golden Root Extract) Supplementation on Anaerobic Exercise Performance and Cognitive Function in Resistance-Trained Athletes: A Randomized, Crossover, Double-Blind, and Placebo-Controlled Study.
    Koozehchian MS; Newton AT; Mabrey G; Bonness FM; Rafajlovska R; Naderi A · Nutrients · 2025
    Randomized trial27 participantsMental Focus forRhodiola
  31. Effects of Rhodiola rosea supplementation on mental performance, physical capacity, and oxidative stress biomarkers in healthy men.
    Jówko E; Sadowski J; Długołęcka B; Gierczuk D; Opaszowski B; Cieśliński I · Journal of sport and health science · 2022
    Randomized trial26 participantsMental Focus forRhodiola