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Ligament Restore

Pure Encapsulations
4.8
★ ★ ★ ★ ★
(21 ratings)
Proline 250 mg
Lysine 250 mg
Silicon 7.5 mg
Collagen 200 mg
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Score70
A broad connective-tissue formula with useful vitamin C and amino acids. Low collagen depth, unstandardized silica, animal allergens, and high cost are major trade-offs.
How scoring works
Quantity:120 Capsule(s) • (60 servings)
Goals:
Nail Health
Hair Health

Score 70

A broad connective-tissue formula with useful vitamin C and amino acids. Low collagen depth, unstandardized silica, animal allergens, and high cost are major trade-offs.
How scoring works
$74.00($1.23 per serving)
Pure Formulas
$ 74.00
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Analysis

Vitamin C, lysine, proline, collagen, and bamboo silica cover several structural pathways relevant to nails and hair fibers. Glucosamine, devil's claw, and turmeric shift part of the formula toward joint and ligament support.

The 200 mg collagen amount is far below common collagen-protein servings, and lysine and proline are only moderate. Bamboo silica lacks standardization, so its elemental silicon contribution is limited to a maintenance range.

Two capsules provide ingredient breadth, but not deep dosing for most target actives. The high serving cost is difficult to justify for focused collagen, lysine, or silicon use.

Who is it for
  • Adults seeking a broad connective-tissue blend
  • Non-vegetarian users without shellfish allergy
  • People prioritizing nail support over high-dose collagen
Best for
  • Multi-pathway nail nutrition
  • Combined amino acid and vitamin C support
  • Ligament-oriented supplementation

Pros

  • Includes branded BioCell Collagen
  • Provides lysine and proline
  • Vitamin C supports collagen formation
  • Bamboo silica amount is disclosed

Cons

  • Collagen amount is very low
  • Silica is not standardized
  • Lysine and proline are only moderate
  • High serving cost

Warnings

  • Crab- and shrimp-derived glucosamine makes the product unsuitable for people with shellfish allergy
  • Chicken cartilage makes it unsuitable for people avoiding poultry-derived ingredients
  • Devil's claw, turmeric, and glucosamine may require review with anticoagulant or antiplatelet medicines

Nutrient quality

81 Highest impact

Glucosamine, vitamin C, amino acids, collagen, silica, and botanical extracts form a coherent connective-tissue formula. Meaningful glucosamine is offset by modest collagen, amino-acid, and botanical amounts.

Ingredient transparency

81 Highest impact

All listed actives have stated amounts, specific names, and no hidden proprietary blend. Intake directions and non-active ingredients are missing from the supplied details, and some extract standardization remains unclear.

Customer satisfaction

61 Moderate impact

The supplied average rating is very strong, but the review count is small. No detailed feedback is available to assess repeated concerns or consistent alignment with the product's purpose.

Value for money

51 Moderate impact

Meaningful glucosamine and a coherent ingredient mix provide some value in one serving. Modest collagen, amino-acid, silica, and botanical doses make the premium positioning difficult to justify.

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Goals

Nail Health
Nail Health
Impact
High effect
B Goal FitC+ Strength of SupportB CoverageB- Formula Quality
Silicon · 7.5 mgCollagen · 200 mg

Vitamin C, collagen, proline, lysine, and bamboo silica create a coherent structural formula with clear relevance to nail integrity. The collagen amount is far below common structural-protein servings, so the label is stronger in breadth than depth.

Silica reaches a maintenance amount and the amino acids are clearly disclosed, but collagen is only 200 mg. Crab- and shrimp-derived glucosamine may be unsuitable for people with shellfish allergy.

Study evidence
Collagen Supportive 4 studies
Silicon Supportive 2 studies
Vitamin C Supportive 1 study
Hair Health
Hair Health
Impact
Moderate effect
C Goal FitD Strength of SupportD+ CoverageB- Formula Quality
Lysine · 250 mgVitamin C · 100 mgCollagen · 200 mg

Collagen, lysine, proline, silica, and vitamin C form a relevant structural combination for hair fibers. Most of these actives are supplied below stronger hair-focused amounts.

Branded collagen and lysine hydrochloride improve form quality, while silica standardization is absent. Crab- and shrimp-derived glucosamine makes the capsules unsuitable for users with shellfish allergy.

Study evidence
Collagen Supportive 3 studies
Lysine Supportive 1 study
Silicon Supportive 2 studies
Vitamin C Mixed 5 studies

Ingredients

IngredientAmount per serving
Vitamin C (Ascorbic Acid)
 100 mg
Glucosamine Sulfate (Crab, Shrimp)
 750 mg
BioCell Collagen (Chicken Sternal Cartilage)
 200 mg
L-Proline
250 mg
L-Lysine Hydrochloride
250 mg
Silica (Bamboo)
 7.5 mg
Devil's Claw (Harpagophytum procumbens and Harpagophytum zeyheri) extract (Harpagosides)
 50 mg
Turmeric Root Extract (Curcuminoids)
 50 mg
Gluten Free Adults 18–50
Report overview
Proline · 250 mg OverallScore75
A+ Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyF Value

Clearly identified L-proline is supplied in a practical capsule format. The amount is moderate and complements the collagen-focused formula without reaching a high targeted dose. High cost per target amount makes it weak value when proline is the main goal.

View ingredientView products
Lysine · 250 mg OverallScore52
B- Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyF Value

The bioavailable hydrochloride form is a clear quality strength, but the lysine amount remains below the main effective range. A two-capsule serving and missing additive details further limit convenience and label confidence. Vitamin C adds useful support, while crab- and shrimp-derived glucosamine makes the formula unsuitable for people with shellfish allergy.

View ingredientView products
Silicon (Bamboo) · 7.5 mg OverallScore51
D Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyF Value

Bamboo-derived silica provides a recognizable botanical source without high-silica standardization. The silica amount converts to about 3.5 mg of elemental silicon in the maintenance range. The high serving cost provides poor value for a maintenance dose without standardization.

View ingredientView products
Loading alternative details
81 Performance

Hair Skin & Nails Collagen Plus Formula

Life Extension
<p>Its label clearly provides 18mg NE of Niacin as Niacinamide, making it a more clearly defined silicon and collagen option. Compared with the original, its ingredient and goal alignment is stronger, although it does not retain the original product’s lysine and proline coverage.</p>
84 Performance

Pro-Rite

Carlson
<p>Its label clearly provides 500 mg of L-Lysine as Lysine Monohydrochloride, making it a more clearly defined lysine and proline option. Compared with the original, its ingredient and goal alignment is stronger, although it does not retain the original product’s silicon and collagen coverage.</p>
73 Performance

Ortho C+ Lemon Flavor

AOR Advanced Orthomolecular Research Premium
<p>Its label clearly provides 3000 mg of Vitamin C as Ascorbic Acid, making it a more clearly defined lysine and proline option. Compared with the original, its ingredient and goal alignment is stronger, although it does not retain the original product’s silicon and collagen coverage.</p>
68 Budget

Alive! Hair Skin & Nails Gummies Delicious Strawberry Flavored

Nature's Way
<p>Its label clearly provides 450 mcg of Vitamin A as Retinyl Palmitate, preserving relevant silicon and collagen coverage. Compared with the original, it lowers the serving cost, although it does not retain the original product’s lysine and proline coverage.</p>
65 Budget

Vegan Collagen Builder +

Amen
<p>Its label clearly provides 300 mg of Vitamin C as Ascorbic Acid, preserving relevant silicon and lysine and proline coverage. Compared with the original, it lowers the serving cost, although it does not retain the original product’s collagen coverage.</p>
83 Budget

Marine Collagen 2500 mg

youtheory
<p>Its label clearly provides 900 mcg of Vitamin A as Beta-Carotene, preserving relevant silicon and collagen coverage. Compared with the original, it lowers the serving cost, although it does not retain the original product’s lysine and proline coverage.</p>
71 Value

Hair & Skin Strawberry Flavor

Noor Vitamins
<p>Its label clearly provides 2 g of Sugar, keeping the formula relevant to silicon and collagen. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although it does not retain the original product’s lysine and proline coverage.</p>
84 Value

Pro-Rite

Carlson
<p>Its label clearly provides 500 mg of L-Proline, keeping the formula relevant to lysine and proline. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although it does not retain the original product’s silicon and collagen coverage.</p>
82 Value

Skin Nails & Hair

Solgar
<p>Its label clearly provides 120 mg of Vitamin C as L-Ascorbic Acid, keeping the formula relevant to silicon and proline. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although it does not retain the original product’s lysine and collagen coverage.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin.
    Barel A; Calomme M; Timchenko A; De Paepe K; Demeester N; Rogiers V; Clarys P; Vanden Berghe D · Archives of dermatological research · 2006
    Randomized trial50 participantsHair Health Nail Health forSilicon
  2. Causes of hair loss and the developments in hair rejuvenation.
    Rushton DH; Norris MJ; Dover R; Busuttil N · International journal of cosmetic science · 2010
    Narrative reviewHair Health forLysine
  3. Low-Molecular-Weight Collagen Peptide Supplementation Improves Cellulite Severity, Skin Elasticity, and Hair Shaft Diameter: A Clinical Study with Pharmacokinetic Evaluation.
    Hwang S; Won J; Kim S; Kang W; Park M · Journal of medicinal food · 2026
    Randomized trial114 participantsHair Health forCollagen
  4. Calcium and Vitamin D Supplementation with and Without Collagen on Bone Density and Skin Elasticity in Menopausal Women-A Randomized Controlled Study.
    Duangjai A; Srivilai J; Nangola S; Amornlerdpison D · Clinics and practice · 2025
    Randomized trialHair Health forCollagen
  5. Dietary Collagen Supplementation as a Strategy for Skin Health: A Narrative Review of Clinical Effects on Skin, Hair, Nails, and Wound Healing.
    Biełach-Bazyluk A; Jurga M; Flisiak I; Zbroch E · Nutrients · 2026
    Narrative reviewHair Health forCollagen
  6. Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails.
    Hexsel D; Zague V; Schunck M; Siega C; Camozzato FO; Oesser S · Journal of cosmetic dermatology · 2018
    Single-arm trial25 participantsNail Health forCollagen
  7. Influence of collagen peptide supplementation on visible signs of skin and nail health and -aging in an East Asian population: A double blind, randomized, placebo-controlled trial.
    Vleminckx S; Virgilio N; Asserin J; Prawitt J; Silva CIF · Journal of cosmetic dermatology · 2024
    Randomized trial85 participantsNail Health forCollagen
  8. Nail Supplements: When, How, and Why?
    Zaraa I; Richert B · Skin appendage disorders · 2026
    Narrative reviewNail Health forSilicon Nail Health forCollagen
  9. Effect of oral intake of choline-stabilized orthosilicic acid on hair tensile strength and morphology in women with fine hair
    R R Wickett, E Kossmann, A Barel, N Demeester, P Clarys, D Vanden Berghe, M Calomme · Archives of Dermatological Research · 2007
    Randomized trial48 participantsHair Health forSilicon
  10. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  11. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
    Methods validation study201,019 participantsHair Health forVitamin C
  12. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  13. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
    Methods validation studyHair Health forVitamin C
  14. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
    Case reportHair Health forVitamin C
  15. Expanding the COL7A1 mutation database: novel and recurrent mutations and unusual genotype-phenotype constellations in 41 patients with dystrophic epidermolysis bullosa.
    Kern JS; Kohlhase J; Bruckner-Tuderman L; Has C · The Journal of investigative dermatology · 2006
    Observational study41 participantsNail Health forCollagen
  16. Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient.
    Dunleavy KA; Ungaro RC; Manning L; Gold S; Novak J; Colombel JF · Crohn's & colitis 360 · 2023
    Other20 participantsNail Health forVitamin C