PureBalance Seratonin
Quality Of Life
PureBalance Seratonin
4.3
★ ★ ★ ★ ★
(1307 ratings)
Rhodiola
5-HTP 33 mg
Theanine 67 mg
Score 78.0
A comprehensive blend for mood, stress, and focus, featuring well-known adaptogens and neurotransmitter precursors. While the combination is excellent, some ingredient dosages are on the moderate to lower side, which might impact the potency for some individuals.
Quantity: 90 Capsule(s)Servings size: 1 Capsule(s) (90 servings)
Selected goals:
Other goals:
Mental Focus
Mood Support
Energy
Stress Relief
Anti-Inflammatory Support
leaderboard Score 78.0
A comprehensive blend for mood, stress, and focus, featuring well-known adaptogens and neurotransmitter precursors. While the combination is excellent, some ingredient dosages are on the moderate to lower side, which might impact the potency for some individuals.
insights Analysis
PureBalance Serotonin by Quality Of Life is formulated to address a spectrum of mental well-being concerns, encompassing mood support, stress relief, mental focus, and sleep. Its strength lies in the synergistic combination of well-researched ingredients: Rhodiola (an adaptogen for stress resilience and mental clarity), Relora (a proprietary blend of Magnolia and Phellodendron bark extracts known for cortisol management), L-Theanine (an amino acid promoting calm focus), and 5-HTP (a precursor to serotonin, vital for mood and sleep). While this multi-faceted approach is commendable, a closer look at dosages reveals that 5-HTP (33mg) and L-Theanine (67mg) are on the lower side compared to common effective doses (50-200mg for 5-HTP, 100-200mg for L-Theanine). The Rhodiola (120mg) is also at the lower end of the commonly recommended range (200-600mg). The negligible amount of Vitamin D3 (6.68mcg or 267 IU) does not contribute meaningfully as a general vitamin D supplement. Despite these moderate dosages, the high volume of positive online reviews suggests that many users experience beneficial effects, likely due to the combined action of the ingredients. The product's price point per serving ($0.43) is quite favorable for a comprehensive blend of this nature.
- Contains a synergistic blend of well-researched ingredients targeting multiple aspects of mental well-being.
- Includes effective adaptogens like Rhodiola and Relora for stress resilience and cortisol management.
- Features 5-HTP and L-Theanine, which are crucial for mood regulation, relaxation, and sleep support.
- Offers a good value for a multi-ingredient formula at its price per serving.
- High number of positive reviews indicate general user satisfaction and perceived efficacy.
- Individual dosages of 5-HTP (33mg) and L-Theanine (67mg) are lower than typical standalone therapeutic doses.
- The Rhodiola dosage (120mg) is on the lower end compared to common research-backed amounts.
- The Vitamin D3 content is negligible and does not provide meaningful nutritional support.
- Relora is a proprietary blend, meaning specific quantities of its components (Magnolia and Phellodendron) are not disclosed.
- Individuals taking antidepressant medications (SSRIs, MAOIs) or other serotonin-modulating drugs should consult a healthcare professional before use due to the risk of serotonin syndrome from 5-HTP.
- May cause mild drowsiness or gastrointestinal upset in sensitive individuals, especially when first introduced.
- Not recommended for pregnant or nursing women without prior medical consultation.
$38.87($0.43 per serving)
 iHerb | $ 38.87 | |
 Amazon | $ 39.96 |
bolt Effectiveness for goals
L-5-Hydroxytryptophan (5-HTP) is a compound that the body converts into serotonin, a neurotransmitter associated with mood, sleep, and appetite regulation. By providing a precursor to serotonin, it may help support balanced mood. It is derived from the Griffonia simplicifolia plant.
Rhodiola root extract is an adaptogen, meaning it may help the body adapt to physical and psychological stressors. It may contribute to reduced feelings of fatigue and improved mental performance during stressful periods. Its effects are often associated with supporting the body's natural stress response.
L-Theanine is an amino acid commonly found in tea leaves, known for its ability to promote relaxation without causing drowsiness. It is believed to increase alpha brain wave activity, which is associated with a relaxed, alert mental state. This may help to reduce feelings of restlessness and support focus.
Proprietary blends, such as Relora (typically a combination of Magnolia bark and Phellodendron extracts), are often formulated to help manage stress and promote relaxation. These ingredients may work by supporting healthy cortisol levels, a hormone associated with the body's stress response. The blend aims to alleviate stress-related symptoms without sedation.
Ingredients such as adaptogens (Rhodiola), serotonin precursors (5-HTP), and calming amino acids (L-Theanine) are often combined to offer comprehensive support for mood and stress. The synergistic effect aims to address multiple pathways involved in emotional balance and the body's response to stress. This multifaceted approach may contribute to an enhanced sense of well-being.
schedule Dosage, timing & forms
Many individuals prefer to take this type of blend in the morning or early afternoon to support mood and stress management throughout the day. If significant relaxation or sleep support is desired, some components like 5-HTP may be taken closer to bedtime. Always follow specific product instructions for the best approach.
5-HTP is often recommended to be taken with a meal to minimize potential gastrointestinal discomfort, although some sources suggest taking it on an empty stomach for better absorption. For sleep support, it is typically taken 30-60 minutes before bedtime. Following the product's specific instructions is key.
For general well-being and stress adaptation, Rhodiola root extract is often used in dosages ranging from 100-300mg, typically taken once or twice daily. It is frequently recommended in the morning or early afternoon to avoid potential mild stimulation before sleep. Consult product labeling for specific dosage recommendations.
L-Theanine can be taken at various times depending on the desired effect. For mental focus and calm alertness, it's often taken in the morning or before mentally demanding tasks. For relaxation and sleep support, it can be taken in the evening or before bedtime.
Cholecalciferol is the most common and effective form of Vitamin D3, identical to the vitamin D produced by the body. It is fat-soluble, meaning it is best absorbed when taken with a meal containing fats to maximize its bioavailability. This form is highly effective at raising and maintaining vitamin D levels.
health_and_safety Safety & interactions
Combining 5-HTP with antidepressants, such as SSRIs or MAOIs, or other serotonergic drugs can lead to an excess of serotonin in the body. This condition, known as serotonin syndrome, may cause symptoms like agitation, rapid heart rate, confusion, and muscle rigidity. It is crucial to consult a healthcare professional before combining these substances.
Yes, ingredients like 5-HTP, Rhodiola, and L-Theanine may interact with certain medications. 5-HTP can interact with antidepressants and sedatives, while Rhodiola may affect medications for blood pressure or blood sugar. L-Theanine can also influence blood pressure drugs, so professional advice is recommended.
Rhodiola root extract may have a mild impact on blood pressure and blood sugar levels in some individuals. Those taking medications for hypertension or diabetes should monitor their levels closely. Consulting a healthcare provider before use is recommended to assess potential interactions.
Relora Proprietary Blend, which typically contains extracts of Magnolia and Phellodendron, can have sedative effects. Combining it with other sedative medications, such as benzodiazepines or sleep aids, may enhance drowsiness and could potentially lead to increased sedation. It is advisable to consult a healthcare professional to avoid excessive central nervous system depression.
L-Theanine can sometimes cause a slight decrease in blood pressure. If you are taking medication for high blood pressure, combining it with L-Theanine might lead to an additive effect, potentially lowering blood pressure too much. Monitoring blood pressure is advisable, and discussing use with a doctor is recommended.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin D3 | 6.68 mcg |
L-5-Hydroxytryptophan | 33 mg |
L-Theanine | 67 mg |
Relora Proprietary Blend | 250 mg |
Rhodiola root extract | 120 mg |
Categories
Rhodiola 70.0
The product contains 120mg of Rhodiola root extract. While beneficial as part of a blend, this dosage is lower than many standalone Rhodiola supplements, which typically range from 200-500mg for optimal adaptogenic effects.
Theanine 65.0
With 67mg of L-Theanine, the product provides a beneficial amount for relaxation and focus. However, for a more pronounced calming or focus-enhancing effect, standalone L-Theanine supplements often provide 100mg to 200mg per dose.
5-HTP 60.0
The L-5-Hydroxytryptophan content is 33mg per serving. This is a relatively low dose compared to common therapeutic applications of 5-HTP, which usually start at 50mg and can go up to 200mg for mood or sleep support.
Goals
Stress Relief 85.0
This product excels in stress relief due to the powerful combination of Rhodiola, Relora, and L-Theanine. These ingredients collectively work as adaptogens and anxiolytics, helping the body manage the physiological and psychological effects of stress.
Mood Support 80.0
The inclusion of 5-HTP directly supports serotonin synthesis, a key neurotransmitter for mood regulation. Rhodiola and Relora further aid mood by improving the body's response to stress, which often impacts emotional well-being.
Mental Focus 75.0
Rhodiola is known to enhance cognitive function and reduce mental fatigue, while L-Theanine promotes a state of calm alertness, both contributing positively to mental focus. However, the dosages present are not at the highest levels seen in dedicated cognitive supplements.
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