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ResveraCel

Thorne
4.6
★ ★ ★ ★ ★
(4429 ratings)
Betaine Anhydrous 85 mg
Niacin 415 mg
Resveratrol 150 mg
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Score79
A focused premium healthy-aging formula with strong ingredient logic and enhanced quercetin delivery, though cost and active-yield clarity remain drawbacks.
How scoring works
Quantity:60 Capsule(s) • (30 servings)
Goals:
Anti-Inflammatory Support
Anti-Aging
Metabolism Boost
Heart Health
Cardiovascular Support
Skin Health

Score 79

A focused premium healthy-aging formula with strong ingredient logic and enhanced quercetin delivery, though cost and active-yield clarity remain drawbacks.
How scoring works
$60.00($2.00 per serving)
iHerb
$ 60.00
Vitacost
$ 60.00
Vitacost
$ 60.00
Amazon
$ 108.00
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Analysis

Nicotinamide riboside hydrogen malate provides a substantial NAD-related ingredient, supported by 150 mg trans-resveratrol and 85 mg betaine. Quercetin phytosome uses a phospholipid complex that may improve absorption compared with plain quercetin.

The formula is concise and each ingredient has a clear role in cellular energy, antioxidant defense, or methylation support. The supplied data lists the phytosome complex and plant source separately, so the actual quercetin yield is not fully clear.

It best fits adults who want a premium, streamlined healthy-aging formula rather than a broad multivitamin. The serving cost is high, but fewer token ingredients and strong goal alignment make the value more defensible than in crowded blends.

Who is it for
  • Adults seeking focused healthy-aging support
  • Users interested in nicotinamide riboside
  • People who prefer a concise premium formula
Best for
  • Healthy-aging support
  • Cellular energy pathways
  • Antioxidant and metabolic support

Pros

  • Provides a substantial nicotinamide riboside complex
  • Uses trans-resveratrol
  • Includes absorption-enhanced quercetin phytosome
  • Focused formula without many token doses

Cons

  • High serving cost
  • Actual quercetin yield is not fully clear
  • Betaine amount is modest for standalone use
  • Not designed for weight gain despite the listed goal

Warnings

  • Resveratrol and quercetin may add to bleeding risk with anticoagulant or antiplatelet medicines
  • Nicotinamide riboside may cause mild digestive upset in sensitive users
  • People using chemotherapy or other treatment where high-dose antioxidants are restricted should review resveratrol and quercetin use with their care team

Nutrient quality

88 Highest impact

Useful delivery forms and substantial core amounts create a focused healthy-aging formula. The formula is balanced and avoids obvious low-value padding.

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Ingredient transparency

76 High impact

The main active amounts are generally available and no broad proprietary blend obscures the formula. Complete usage directions and non-active ingredients are not supplied, while any noted duplicate or vague entries reduce clarity.

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Customer satisfaction

71 High impact

Aggregate satisfaction is strong and supported by an extensive evidence base. No firsthand experience details are supplied, so recurring complaints and purpose alignment remain uncertain.

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Value for money

79 High impact

Good forms and a focused composition support credible formula value. Premium positioning makes the cost-benefit case less competitive for users who do not specifically want these actives.

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Report analysis

Goals

Anti-Inflammatory Support
Impact
Highest effect
A- Goal FitA Strength of SupportA CoverageA Formula Quality

Absorption-enhanced quercetin and trans-resveratrol provide two well-matched polyphenol pathways relevant to inflammatory signaling and oxidative stress. Nicotinamide riboside and betaine add cellular-energy and methylation support.

Quercetin and resveratrol are supplied at substantial, clearly identified amounts, giving the formula useful depth. Resveratrol can have antiplatelet effects, so the combination warrants caution with anticoagulant or antiplatelet medicines.

Study evidence
Resveratrol Supportive 34 studies
Anti-Aging
Impact
Highest effect
B+ Goal FitA- Strength of SupportA CoverageA+ Formula Quality

Nicotinamide riboside directly supports NAD metabolism, while quercetin phytosome, trans-resveratrol, and betaine add antioxidant, sirtuin-related, and methylation support. The formula is specifically designed around several prominent biological-aging pathways.

The key actives use substantial, individually stated amounts and favorable forms. Human data show that nicotinamide riboside raises NAD levels, but proof of broad healthspan improvement remains incomplete.

Study evidence
Resveratrol No effect 7 studies
Metabolism Boost
Impact
Highest effect
B- Goal FitA- Strength of SupportB CoverageA Formula Quality
Niacin · 415 mgResveratrol · 150 mg

Nicotinamide riboside targets cellular NAD metabolism, while resveratrol, quercetin, and betaine add antioxidant and methylation support. The combination is relevant to mitochondrial health, but human evidence for a meaningful metabolism boost remains emerging.

Main actives are fully disclosed and quercetin uses a phytosome delivery system. The formula covers several cellular pathways at useful amounts without relying on a large ingredient list.

Study evidence
Niacin Supportive 17 studies
Resveratrol Supportive 21 studies
Heart Health
Impact
High effect
B- Goal FitB+ Strength of SupportB CoverageA- Formula Quality

Trans-resveratrol and quercetin phytosome may support endothelial and antioxidant pathways, while nicotinamide riboside supports cellular metabolism. Cardiovascular evidence is promising but less direct and consistent than for EPA, DHA, or CoQ10.

The main actives have meaningful disclosed amounts and favorable form detail, especially trans-resveratrol and the phytosome delivery. Betaine is modest, but the formula remains coherent and avoids a hidden blend.

Study evidence
Niacin Supportive 105 studies
Resveratrol Supportive 66 studies
Cardiovascular Support
Impact
High effect
B- Goal FitB- Strength of SupportB- CoverageA- Formula Quality
Niacin · 415 mg

Resveratrol provides a relevant route to cardiovascular support. Dose or form uncertainty limits confidence in the practical contribution.

Several complementary pathways broaden the formula. Vitamin K can oppose warfarin and related vitamin-K-antagonist medicines, so the intake should remain medically coordinated and consistent.

Study evidence
Resveratrol Supportive 73 studies
Skin Health
Impact
High effect
C+ Goal FitB Strength of SupportC CoverageB Formula Quality
Resveratrol · 150 mg

Trans-resveratrol and quercetin provide a plausible antioxidant approach to environmental skin stress, while nicotinamide riboside adds indirect cellular support. The formula does not directly supply collagen building blocks or moisture-barrier ingredients, and oral evidence for visible skin benefits is still limited.

Specific forms and amounts are mostly clear, including a phospholipid quercetin complex that may aid absorption. Resveratrol and quercetin may add to the effects of anticoagulant or antiplatelet medicines, so this combination warrants medication review for people using those drugs.

Study evidence
Niacin Supportive 61 studies
Resveratrol Supportive 7 studies

Ingredients

IngredientAmount per serving
Nicotinamide Riboside Hydrogen Malate
415 mg
Quercetin Phytosome (Phospholipid Complex, Sophora japonica Flower Extract)
250 mg
Trans-Resveratrol
150 mg
Betaine Anhydrous
85 mg
Gluten Free Adults 18–50
Report overview
Betaine Anhydrous · 85 mg OverallScore87
A+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyB Value

The explicitly named anhydrous form is suitable for wellness and methylation use. Its amount is moderate rather than fully aligned with the stronger wellness target. A nicotinamide riboside precursor, resveratrol, and a specialized quercetin complex support reasonable value at the near-median serving cost.

Niacin · 415 mg OverallScore76
A- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value

Nicotinamide riboside supplies a research-relevant amount for energy and NAD support. Quercetin, resveratrol, and betaine broaden the formula, but no stabilization or verified precursor source is stated. The higher serving cost weakens its value when judged mainly as a niacin product.

Resveratrol · 150 mg OverallScore46
C Active Ingredient Quality & BioavailabilityD Dose, Safety & Label TransparencyF Value

The preferred trans-isomer is clearly identified at a supportive amount. Standard capsule delivery and absent purity standardization leave room for better absorption and quality disclosure. A high cost per equivalent active dose limits resveratrol-focused value.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of resveratrol on memory performance, hippocampus connectivity and microstructure in older adults - A randomized controlled trial.
    Huhn S; Beyer F; Zhang R; Lampe L; Grothe J; Kratzsch J; Willenberg A; Breitfeld J; Kovacs P; Stumvoll M; Trampel R; Bazin PL; Villringer A; Witte AV · NeuroImage · 2019
    Randomized trial60 participantsAnti-Aging forResveratrol
  2. Impact of Resveratrol Supplementation on Human Sirtuin 1: A Grading of Recommendations Assessment, Development and Evaluation-Assessed Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.
    Mansouri F; Feliziani G; Bordoni L; Gabbianelli R · Journal of the Academy of Nutrition and Dietetics · 2025
    Meta-analysis11 studies pooledAnti-Aging forResveratrol
  3. Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults.
    Witte AV; Kerti L; Margulies DS; Flöel A · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
    Randomized trial46 participantsAnti-Aging forResveratrol
  4. Resveratrol levels and all-cause mortality in older community-dwelling adults.
    Semba RD; Ferrucci L; Bartali B; Urpí-Sarda M; Zamora-Ros R; Sun K; Cherubini A; Bandinelli S; Andres-Lacueva C · JAMA internal medicine · 2014
    Cohort study783 participantsAnti-Aging forResveratrol
  5. Trans-resveratrol reduces visible signs of skin ageing in healthy adult females over 40: an 8-week randomized placebo-controlled trial.
    Rao A; Briskey D; Roche G; Tremblay A; Da Silva Pinto M; Tompkins TA · Frontiers in aging · 2026
    Randomized trial134 participantsAnti-Aging Skin Health forResveratrol
  6. Role of resveratrol supplementation in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2: A randomized, placebo-controlled trial.
    Mahjabeen W; Khan DA; Mirza SA · Complementary therapies in medicine · 2022
    Randomized trial110 participantsAnti-Inflammatory Support forResveratrol
  7. Resveratrol decreases local inflammatory markers and systemic endotoxin in patients with aggressive periodontitis.
    Zhang Q; Xu S; Xu W; Zhou Y; Luan H; Wang D · Medicine · 2022
    Randomized trial160 participantsAnti-Inflammatory Support forResveratrol
  8. Effects of resveratrol supplementation on inflammatory markers, fatigue scale, fasting blood sugar and lipid profile in relapsing-remitting multiple sclerosis patients: a double-blind, randomized placebo-controlled trial.
    Keramatzadeh S; Hosseini SA; Majdinasab N; Cheraghian B; Zilaee M · Nutritional neuroscience · 2025
    Randomized trial55 participantsAnti-Inflammatory Support forResveratrol
  9. One-year consumption of a grape nutraceutical containing resveratrol improves the inflammatory and fibrinolytic status of patients in primary prevention of cardiovascular disease.
    Tomé-Carneiro J; Gonzálvez M; Larrosa M; Yáñez-Gascón MJ; García-Almagro FJ; Ruiz-Ros JA; García-Conesa MT; Tomás-Barberán FA; Espín JC · The American journal of cardiology · 2012
    Randomized trial75 participantsAnti-Inflammatory Support forResveratrol
  10. Effects of resveratrol supplementation on risk factors of non-communicable diseases: A meta-analysis of randomized controlled trials.
    Guo XF; Li JM; Tang J; Li D · Critical reviews in food science and nutrition · 2019
    Meta-analysis1,069 participants29 studies pooledAnti-Inflammatory Support forResveratrol
  11. Consumption of a grape extract supplement containing resveratrol decreases oxidized LDL and ApoB in patients undergoing primary prevention of cardiovascular disease: a triple-blind, 6-month follow-up, placebo-controlled, randomized trial.
    Tomé-Carneiro J; Gonzálvez M; Larrosa M; García-Almagro FJ; Avilés-Plaza F; Parra S; Yáñez-Gascón MJ; Ruiz-Ros JA; García-Conesa MT; Tomás-Barberán FA; Espín JC · Molecular nutrition & food research · 2012
    Randomized trial75 participantsCardiovascular Support forResveratrol
  12. Resveratrol improves lipid profile and recovers heart function in postoperative CABG patients.
    Ahmadi P; Akbarzadeh S; Alizadeh M; Mohammadi N; Mahmoodi M; Amini A; Netticadan T; Rezaei M; Movahed A · Molecular and cellular biochemistry · 2025
    Randomized trial60 participantsCardiovascular Support forResveratrol
  13. Resveratrol Supplementation and its Potential Benefits in Obesity-related Non-communicable Diseases.
    Shen CY; Li CP; Yu JT; Ho YJ; Tsai RY · In vivo (Athens, Greece) · 2026
    Meta-analysis2,551 participants40 studies pooledCardiovascular Support forResveratrol
  14. Chronic resveratrol consumption improves brachial flow-mediated dilatation in healthy obese adults.
    Wong RH; Berry NM; Coates AM; Buckley JD; Bryan J; Kunz I; Howe PR · Journal of hypertension · 2014
    Randomized trial28 participantsCardiovascular Support Heart Health forResveratrol
  15. Effect of resveratrol supplementation on lipid profile in subjects with dyslipidemia: A randomized double-blind, placebo-controlled trial.
    Simental-Mendía LE; Guerrero-Romero F · Nutrition (Burbank, Los Angeles County, Calif.) · 2020
    Randomized trial71 participantsCardiovascular Support forResveratrol
  16. Differential effect of two nicotinic acid preparations on low-density lipoprotein subclass distribution in patients classified as low-density lipoprotein pattern A, B, or I.
    Superko HR; McGovern ME; Raul E; Garrett B · The American journal of cardiology · 2004
    Randomized trial180 participantsHeart Health forNiacin
  17. The ARBITER 6-HALTS Trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6-HDL and LDL Treatment Strategies in Atherosclerosis): final results and the impact of medication adherence, dose, and treatment duration.
    Villines TC; Stanek EJ; Devine PJ; Turco M; Miller M; Weissman NJ; Griffen L; Taylor AJ · Journal of the American College of Cardiology · 2010
    Randomized trial315 participantsHeart Health forNiacin
  18. The effects of extended-release niacin on carotid intimal media thickness, endothelial function and inflammatory markers in patients with the metabolic syndrome.
    Thoenes M; Oguchi A; Nagamia S; Vaccari CS; Hammoud R; Umpierrez GE; Khan BV · International journal of clinical practice · 2008
    Randomized trial50 participantsHeart Health forNiacin
  19. Effect of niacin therapy on cardiovascular outcomes in patients with coronary artery disease.
    Duggal JK; Singh M; Attri N; Singh PP; Ahmed N; Pahwa S; Molnar J; Singh S; Khosla S; Arora R · Journal of cardiovascular pharmacology and therapeutics · 2010
    Meta-analysis5,137 participants7 studies pooledHeart Health forNiacin
  20. Effect of niacin on endothelial function: a systematic review and meta-analysis of randomized controlled trials.
    Sahebkar A · Vascular medicine (London, England) · 2014
    Meta-analysis441 participants7 studies pooledHeart Health forNiacin
  21. A Meta-Analysis of the Impact of Resveratrol Supplementation on Markers of Renal Function and Blood Pressure in Type 2 Diabetic Patients on Hypoglycemic Therapy.
    Nyambuya TM; Nkambule BB; Mazibuko-Mbeje SE; Mxinwa V; Mokgalaboni K; Orlando P; Silvestri S; Louw J; Tiano L; Dludla PV · Molecules (Basel, Switzerland) · 2021
    Meta-analysis388 participants5 studies pooledHeart Health forResveratrol
  22. Resveratrol Improves Heart Function by Moderating Inflammatory Processes in Patients with Systolic Heart Failure.
    Gal R; Deres L; Horvath O; Eros K; Sandor B; Urban P; Soos S; Marton Z; Sumegi B; Toth K; Habon T; Halmosi R · Antioxidants (Basel, Switzerland) · 2024
    Randomized trial60 participantsHeart Health forResveratrol
  23. Low dose resveratrol improves cerebrovascular function in type 2 diabetes mellitus.
    Wong RH; Nealon RS; Scholey A; Howe PR · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2017
    Randomized trial36 participantsHeart Health forResveratrol
  24. Modified resveratrol Longevinex improves endothelial function in adults with metabolic syndrome receiving standard treatment.
    Fujitaka K; Otani H; Jo F; Jo H; Nomura E; Iwasaki M; Nishikawa M; Iwasaka T; Das DK · Nutrition research (New York, N.Y.) · 2012
    Randomized trial34 participantsHeart Health forResveratrol
  25. Niacin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Boost forNiacin
  26. Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans.
    Fangmann D; Theismann EM; Türk K; Schulte DM; Relling I; Hartmann K; Keppler JK; Knipp JR; Rehman A; Heinsen FA; Franke A; Lenk L; Freitag-Wolf S; Appel E; Gorb S; Brenner C; Seegert D; Waetzig GH; Rosenstiel P; Schreiber S; Schwarz K; Laudes M · Diabetes care · 2018
    Clinical trialMetabolism Boost forNiacin
  27. The differential impact of three different NAD+ boosters on circulatory NAD and microbial metabolism in humans.
    Christen S; Redeuil K; Goulet L; Giner MP; Breton I; Rota R; Frézal A; Nazari A; Van den Abbeele P; Godin JP; Nutten S; Cuenoud B · Nature metabolism · 2026
    Randomized trial65 participantsMetabolism Boost forNiacin
  28. Effects of extended-release niacin on lipid profile and adipocyte biology in patients with impaired glucose tolerance.
    Linke A; Sonnabend M; Fasshauer M; Höllriegel R; Schuler G; Niebauer J; Stumvoll M; Blüher M · Atherosclerosis · 2009
    Randomized trial30 participantsMetabolism Boost forNiacin
  29. Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin-dependent diabetes mellitus.
    Vaag A; Skött P; Damsbo P; Gall MA; Richter EA; Beck-Nielsen H · The Journal of clinical investigation · 1991
    Clinical trial12 participantsMetabolism Boost forNiacin
  30. Effects of resveratrol on glucose control and insulin sensitivity in subjects with type 2 diabetes: systematic review and meta-analysis.
    Zhu X; Wu C; Qiu S; Yuan X; Li L · Nutrition & metabolism · 2022
    Meta-analysis283 participants9 studies pooledMetabolism Boost forResveratrol
  31. Effects of resveratrol supplementation on multiple health outcomes: an umbrella review of systematic reviews and meta-analyses of randomized controlled trials.
    Sun JN; Yang R; Fang L; Li YJ; Xing WY; Sun ML; Wu L; Wu QJ; Gong TT · Nutrition journal · 2026
    Meta-analysis45 studies pooledMetabolism Boost forResveratrol
  32. Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease: a randomized controlled trial.
    Chen S; Zhao X; Ran L; Wan J; Wang X; Qin Y; Shu F; Gao Y; Yuan L; Zhang Q; Mi M · Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2015
    Randomized trial60 participantsMetabolism Boost forResveratrol
  33. Supplementation with resveratrol modified gut microbiota improving insulin sensitivity and lipid metabolism in subjects with obesity and insulin resistance.
    Guevara-Cruz M; Sánchez-Tapia M; Velazquez-Villegas LA; Torre-Villalvazo I; Guizar-Heredia R; Godínez-Salas E; López-Barradas A; Granados O; Torres-Villalobos G; Torres N; Tovar AR · European journal of nutrition · 2026
    Randomized trial32 participantsMetabolism Boost forResveratrol
  34. Efficacy of Resveratrol Supplementation on Glucose and Lipid Metabolism: A Meta-Analysis and Systematic Review.
    Zhou Q; Wang Y; Han X; Fu S; Zhu C; Chen Q · Frontiers in physiology · 2022
    Meta-analysis1,171 participants25 studies pooledMetabolism Boost forResveratrol
  35. The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer.
    Hakozaki T; Minwalla L; Zhuang J; Chhoa M; Matsubara A; Miyamoto K; Greatens A; Hillebrand GG; Bissett DL; Boissy RE · The British journal of dermatology · 2002
    Randomized trial138 participantsSkin Health forNiacin
  36. Niacinamide: A B vitamin that improves aging facial skin appearance.
    Bissett DL; Oblong JE; Berge CA · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2005
    Randomized trial50 participantsSkin Health forNiacin
  37. The clinical anti-aging effects of topical kinetin and niacinamide in Asians: a randomized, double-blind, placebo-controlled, split-face comparative trial.
    Chiu PC; Chan CC; Lin HM; Chiu HC · Journal of cosmetic dermatology · 2008
    Randomized trial52 participantsSkin Health forNiacin
  38. A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention.
    Chen AC; Martin AJ; Choy B; Fernández-Peñas P; Dalziell RA; McKenzie CA; Scolyer RA; Dhillon HM; Vardy JL; Kricker A; St George G; Chinniah N; Halliday GM; Damian DL · The New England journal of medicine · 2015
    Randomized trial386 participantsSkin Health forNiacin
  39. Nicotinamide for Skin Cancer Chemoprevention.
    Breglio KF; Knox KM; Hwang J; Weiss R; Maas K; Zhang S; Yao L; Madden C; Xu Y; Hartman RI; Wheless L · JAMA dermatology · 2025
    Cohort study33,822 participantsSkin Health forNiacin
  40. Efficacy and safety of Resveratrol combined with Ablative Fractional CO2 laser system in the treatment of skin photoaging.
    Du YM; Zeng J; Li M; Wang YB; Wu Y; Qi RQ; Gao XH; Chen HD · Journal of cosmetic dermatology · 2021
    Non-randomized trial32 participantsSkin Health forResveratrol
  41. Exploring resveratrol-enriched collagen dressings for diabetic foot ulcers: A retrospective study of wound healing outcomes.
    Sezikli İ; Kendirci M · Journal of tissue viability · 2025
    Cohort study41 participantsSkin Health forResveratrol
  42. Enhanced antioxidant effect of trans-resveratrol: potential of binary systems with polyethylene glycol and cyclodextrin.
    Moyano-Mendez JR; Fabbrocini G; De Stefano D; Mazzella C; Mayol L; Scognamiglio I; Carnuccio R; Ayala F; La Rotonda MI; De Rosa G · Drug development and industrial pharmacy · 2016
    Clinical trialSkin Health forResveratrol
  43. Resveratrol-Loaded Lipid Nanocarriers: Correlation between In Vitro Occlusion Factor and In Vivo Skin Hydrating Effect.
    Montenegro L; Parenti C; Turnaturi R; Pasquinucci L · Pharmaceutics · 2020
    Clinical trial12 participantsSkin Health forResveratrol