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Biotin Gummies Goji Berry

4.5
★ ★ ★ ★ ★
(4517 ratings)
Biotin 2500 mcg
Vitamin B12 425 mcg
Product Image
Score69
A convenient beauty gummy with biotin, active folate and B12, and zinc citrate. Laboratory-test interference and token-dose fo-ti are the main drawbacks.
How scoring works
Gummy
Quantity:60 Gummy(ies) • (60 servings)
Goals:
Nail Health
Hair Health
General Health
Energy

Score 69

A convenient beauty gummy with biotin, active folate and B12, and zinc citrate. Laboratory-test interference and token-dose fo-ti are the main drawbacks.
How scoring works
$18.71($0.31 per serving)
Vitacost
$ 24.95
iHerb
$ 24.95
Pure Formulas
$ 25.79
Amazon
$ 24.95
Walmart
$ 18.71
Vitacost
$ 24.95
Report prices

Analysis

Biotin at 2,500 mcg is paired with methylcobalamin, methylfolate, and zinc citrate. The combination is relevant to hair, skin, and nail nutrition, and the active forms improve formulation quality.

Fo-ti root extract is included at only 5 mg, too little to add a clear practical benefit. Even at a small amount, an unnecessary botanical makes the formula less clean than a simple nutrient gummy.

The gummy suits adults who prioritize taste and a modest carbohydrate load over capsules. Users should plan around laboratory testing because biotin can distort several common assay results.

Who is it for
  • Adults seeking a gummy for hair, skin, and nail nutrition
  • Users who prefer methylated folate and B12
Best for
  • Convenient biotin supplementation
  • People who avoid capsules

Pros

  • Focused biotin amount
  • Uses methylcobalamin
  • Uses methylfolate
  • Includes zinc citrate

Cons

  • Biotin can interfere with laboratory tests
  • Fo-ti amount is too small to justify its inclusion
  • Gummy adds carbohydrate
  • Not a broad multivitamin

Warnings

  • Biotin at 2,500 mcg can interfere with thyroid, hormone, cardiac, and other laboratory tests; follow the laboratory’s stop-use instructions.
  • Fo-ti has been associated with liver concerns, and its inclusion adds uncertainty despite the small amount.
  • Zinc at 10 mg should be counted with other zinc-containing supplements during regular use.

Nutrient quality

74 High impact

Several nutrient forms are useful and the main amounts are meaningful. High-dose biotin can interfere with laboratory tests, while fo-ti and the gummy base weaken the formula.

.

Ingredient transparency

81 Highest impact

Active names and amounts are clearly stated, with no hidden proprietary dose. Complete intake directions and a full inactive-ingredient list are not included in the supplied data.

.

Customer satisfaction

69 High impact

Supplied satisfaction metrics indicate a strong result with a meaningful response pool. Detailed experience themes are absent, so recurring complaints and real-world purpose fit remain uncertain.

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Value for money

49 Lower impact

Serving value appears weak relative to the disclosed form and amount. Convenience ingredients or minor additions reduce the share of value coming from the core active.

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Report analysis

Goals

Nail Health
Impact
Highest effect
A- Goal FitA Strength of SupportB CoverageB Formula Quality
Biotin · 2500 mcg

Biotin, methylcobalamin, active folate, and zinc support keratin synthesis and nail-matrix cell growth. The gummy does not provide collagen, keratin, silicon, or sulfur amino acids.

The biotin amount is substantial and the vitamin forms are favorable. High-dose biotin can interfere with thyroid, cardiac, and other laboratory tests.

Study evidence
Biotin Supportive 8 studies
Vitamin B12 No effect 4 studies
Zinc No effect 1 study
Hair Health
Impact
High effect
B Goal FitA Strength of SupportB- CoverageB- Formula Quality
Biotin · 2500 mcgZinc · 10 mg

Biotin, zinc, vitamin B12, and methylfolate provide a focused set of nutrients tied to normal follicle activity and deficiency-related shedding. The amounts and useful nutrient forms are clearly disclosed, with biotin reaching a focused-support range.

Benefits are most likely when one of these nutrients is inadequate, since biotin does not reliably improve hair in people with sufficient status. The 2500 mcg biotin amount can interfere with some laboratory tests, so it should be reported before blood work.

Study evidence
Biotin Supportive 4 studies
Folate Mixed 15 studies
Vitamin B12 Disputed 17 studies
Zinc Supportive 22 studies
General Health
Impact
High effect
A- Goal FitA- Strength of SupportB- CoverageC Formula Quality
Folate · 250 mcg DFEVitamin B12 · 425 mcgZinc · 10 mg

Methylcobalamin, methylated folate, and zinc support energy metabolism, blood formation, and immune function. The active forms and amounts are clear, although the gummy provides more biotin than is usually needed for general maintenance.

The formula covers several pathways, but its hair-focused biotin and tiny fo-ti amount weaken the general-health logic. The 2,500 mcg biotin amount can interfere with some thyroid, hormone, and cardiac laboratory tests, so it should be disclosed before testing.

Study evidence
Folate Supportive 80 studies
Vitamin B12 Adverse 66 studies
Zinc Supportive 60 studies
Energy
Impact
High effect
B+ Goal FitA- Strength of SupportC+ CoverageC+ Formula Quality
Vitamin B12 · 425 mcg

Methylcobalamin and active folate provide credible support for B-vitamin metabolism and red blood cell production. Zinc citrate adds a useful maintenance nutrient in a convenient gummy.

Biotin dominates the product concept without offering extra energy in people who are sufficient, and the fo-ti amount is token. The formula is better suited to beauty-focused supplementation than broad energy support.

Study evidence
Vitamin B12 Disputed 14 studies

Ingredients

IngredientAmount per serving
Calories
5 Calorie(s)
Total Carbohydrates
2 Gram(s)
Methylated Folate (Calcium L-5-Methyltetrahydrofolate)
250 mcg DFE
Vitamin B12 (Methylcobalamin)
425 mcg
Biotin
2500 mcg
Zinc (Zinc Citrate)
10 mg
Sodium
10 mg
Fo-Ti Root Extract
5 mg
Adults 18–50 Vegan Dairy Free Sugar Free Vegetarian
Report overview
Biotin · 2500 mcg OverallScore70
C Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyC Value

The biotin amount reaches the lower end of the focused-support range and is clearly disclosed. The gummy is convenient but receives a lower purity rating than a capsule, while methylfolate, methylcobalamin, and zinc broaden its purpose. Supplemental biotin at this level may affect some laboratory tests, so it should be reported before blood work.

B Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyF Value

Methylcobalamin is a high-quality B12 form, but the dose is geared more toward maintenance than higher needs. The gummy format is convenient yet less optimized for absorption than a sublingual or liquid spray. The small active amount makes the cost per equivalent high-dose serving unfavorable.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Interventions for infantile seborrhoeic dermatitis (including cradle cap).
    Victoire A; Magin P; Coughlan J; van Driel ML · The Cochrane database of systematic reviews · 2019
    Systematic review35 participants2 studies pooledSkin Health forBiotin
  2. A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid function tests, zinc, copper, biotin, and selenium levels.
    Durusu Turkoglu IN; Turkoglu AK; Soylu S; Gencer G; Duman R · Journal of cosmetic dermatology · 2024
    Case-control study180 participantsHair Health forVitamin B12
  3. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
  4. Vitamins and minerals: their role in nail health and disease.
    Scheinfeld N; Dahdah MJ; Scher R · Journal of drugs in dermatology : JDD · 2007
    Narrative reviewNail Health forBiotin Nail Health forVitamin B12 Nail Health forZinc
  5. Biotin for the treatment of nail disease: what is the evidence?
    Lipner SR; Scher RK · The Journal of dermatological treatment · 2018
    Narrative reviewNail Health forBiotin
  6. Anti-pollution cosmetic-based one-step formation of w/o/w multiple emulsion containing D-biotin for skin protection: fabrication and in vitro and in vivo evaluation.
    Ali A; Iqbal S; Ilyas A; Khan H; Asad MHHB; Fatima N; Akhtar N · Drug delivery and translational research · 2020
    Non-randomized trial15 participantsSkin Health forBiotin
  7. Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
    Karakoyun Ö; Ayhan E; Yıldız İ · Journal of cosmetic dermatology · 2025
    Cohort study2,851 participantsHair Health forVitamin B12
  8. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  9. Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy.
    Colombo VE; Gerber F; Bronhofer M; Floersheim GL · Journal of the American Academy of Dermatology · 1991
    Other32 participantsNail Health forBiotin
  10. Biotinidase deficiency: the enzymatic defect in late-onset multiple carboxylase deficiency.
    Wolf B; Grier RE; Allen RJ; Goodman SI; Kien CL · Clinica chimica acta; international journal of clinical chemistry · 1983
    Case series5 participantsSkin Health forBiotin
  11. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsSkin Health Hair Health forBiotin
  12. Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
    Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
    Case-control study200 participantsHair Health forVitamin B12 Hair Health forFolate
  13. Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters.
    Aksac SE; Bilgili SG; Yavuz GO; Yavuz IH; Aksac M; Karadag AS · International journal of dermatology · 2021
    Non-randomized trial60 participantsSkin Health forBiotin
  14. Micronutrient levels and thyroid functions in scarring alopecias: Do they play a role in disease pathogenesis?
    Gönülal Bak R; Çetin C; Kılınç F; Akbaş A; Aksoy Saraç G · Cutaneous and ocular toxicology · 2025
    Case-control study136 participantsHair Health forVitamin B12
  15. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsSkin Health Hair Health Nail Health forBiotin
  16. Brittle nails: response to daily biotin supplementation.
    Hochman LG; Scher RK; Meyerson MS · Cutis · 1993
    Case series35 participantsNail Health forBiotin
  17. Generalized seborrhoeic dermatitis. Clinical and therapeutic data of 25 patients.
    Messaritakis J; Kattamis C; Karabula C; Matsaniotis N · Archives of disease in childhood · 1976
    Non-randomized trial25 participantsSkin Health forBiotin
  18. Factors Associated with Premature Hair Graying in a Young Indian Population.
    Chakrabarty S; Krishnappa PG; Gowda DG; Hiremath J · International journal of trichology · 2016
    Case-control study74 participantsHair Health forVitamin B12
  19. Nail Supplements: When, How, and Why?
    Zaraa I; Richert B · Skin appendage disorders · 2026
    Narrative reviewNail Health forBiotin
  20. Hair Loss After Laparoscopic Sleeve Gastrectomy.
    Katsogridaki G; Tzovaras G; Sioka E; Perivoliotis K; Zachari E; Magouliotis D; Tasiopoulou V; Chatedaki C; Zacharoulis D · Obesity surgery · 2019
    Cohort study50 participantsHair Health forVitamin B12
  21. Brittle nails.
    Iorizzo M; Pazzaglia M; M Piraccini B; Tullo S; Tosti A · Journal of cosmetic dermatology · 2009
    Narrative reviewNail Health forBiotin
  22. Dermatological findings of vitamin B12 deficiency and resolving time of these symptoms.
    Demir N; Doğan M; Koç A; Kaba S; Bulan K; Ozkol HU; Doğan SZ · Cutaneous and ocular toxicology · 2014
    Single-arm trial57 participantsHair Health forVitamin B12
  23. Risk Factors for Pediatric Alopecia Areata: Clinical and Biochemical Findings from a Case - Control Study.
    İritaş SY · Dermatology practical & conceptual · 2026
    Case-control study600 participantsHair Health forVitamin B12
  24. Holocarboxylase synthetase deficiency: novel clinical and molecular findings.
    Tammachote R; Janklat S; Tongkobpetch S; Suphapeetiporn K; Shotelersuk V · Clinical genetics · 2010
    Case series4 participantsSkin Health forBiotin
  25. Demographic Characteristics and Association of Serum Vitamin B12, Ferritin and Thyroid Function with Premature Canities in Indian Patients from an Urban Skin Clinic of North India: A Retrospective Analysis of 71 Cases.
    Sonthalia S; Priya A; Tobin DJ · Indian journal of dermatology · 2022
    Cross-sectional study71 participantsHair Health forVitamin B12
  26. Partial biotinidase deficiency: clinical and biochemical features.
    McVoy JR; Levy HL; Lawler M; Schmidt MA; Ebers DD; Hart PS; Pettit DD; Blitzer MG; Wolf B · The Journal of pediatrics · 1990
    Case seriesSkin Health forBiotin
  27. Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center.
    Arslan H; Gündüz Ö · Dermatology practical & conceptual · 2023
    Observational study973 participantsHair Health forVitamin B12
  28. Final report on the safety assessment of biotin.
    Fiume MZ; Cosmetic Ingredient Review Expert Panel · International journal of toxicology · 2002
    Narrative reviewSkin Health forBiotin
  29. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  30. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  31. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  32. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  33. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  34. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsGeneral Health forFolate
  35. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsGeneral Health forFolate
  36. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsGeneral Health forFolate
  37. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewGeneral Health forFolate
  38. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledGeneral Health forFolate
  39. Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
    Randomized trial40 participantsGeneral Health forVitamin B12
  40. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
    Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
    Randomized trial90 participantsGeneral Health forVitamin B12
  41. A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
    Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
    Randomized trial98 participantsGeneral Health forVitamin B12
  42. Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
    Randomized trial204 participantsGeneral Health forVitamin B12
  43. The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
    Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
    Clinical trial50 participantsGeneral Health forVitamin B12
  44. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  45. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  46. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  47. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  48. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  49. Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
    Zhang W; Fan M; Wang C; Mahawar K; Parmar C; Chen W; Yang W; Global Bariatric Research Collaborative · Obesity surgery · 2021
    Meta-analysis2,538 participants18 studies pooledHair Health forFolate
  50. Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
    Saini A; Norman AR; Cunningham D; Chau I; Hill M; Tait D; Hickish T; Iveson T; Lofts F; Jodrell D; Ross PJ; Oates J · British journal of cancer · 2003
    Randomized trialHair Health forFolate
  51. Role of oxaliplatin combined with 5-fluorouracil and folinic acid in the first- and second-line treatment of advanced colorectal cancer.
    Jonker D; Rumble RB; Maroun J; Gastrointestinal Cancer Disease Site Groupof Cancer Care Ontario’s Program in Evidence-Based Care · Current oncology (Toronto, Ont.) · 2012
    Randomized trialHair Health forFolate
  52. Phase I-II study of vinorelbine in combination with 5-fluorouracil and folinic acid as first-line chemotherapy in metastatic breast cancer: a regimen with a low subjective toxic burden.
    Nolè F; de Braud F; Aapro M; Minchella I; De Pas TM; Zampino MG; Monti S; Andreoni G; Goldhirsch A · Annals of oncology : official journal of the European Society for Medical Oncology · 1997
    Randomized trialHair Health forFolate
  53. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  54. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  55. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  56. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  57. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  58. Treatment of brittle nail with a hydroxypropyl chitosan-based lacquer, alone or in combination with oral biotin: A randomized, assessor-blinded trial.
    Chiavetta A; Mazzurco S; Secolo MP; Tomarchio G; Milani M · Dermatologic therapy · 2020
    Randomized trial50 participantsNail Health forBiotin
  59. Reversible hyperpigmentation of vitamin B12 deficiency
    K. Vijayakumar, H. Gopinath · The Indian Journal of Medical Research · 2020
    Other1 participantsNail Health forVitamin B12
  60. A review of vitamin B12 in dermatology
    Jennifer Brescoll, Steven Daveluy · American Journal of Clinical Dermatology · 2015
    OtherNail Health forVitamin B12
  61. Reversible cutaneous hyperpigmentation and nails with white hair due to vitamin B12 deficiency
    Shiro Niiyama, Hideki Mukai · European Journal of Dermatology · 2007
    Other1 participantsNail Health forVitamin B12