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B12 Energizer+ Natural Cherry Flavor

Advanced Nutrition by Zahler
4.7
★ ★ ★ ★ ★
(2215 ratings)
Vitamin B12 5000 mcg
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Score87
A clear, high-potency methylcobalamin product with a generous supply. The amount is excessive for many maintenance users, and flavoring details are incomplete.
How scoring works
Quantity:120 Liquid(s) • (120 servings)
Goals:
Energy
General Health
Hair Health
Productivity Boost

Score 87

A clear, high-potency methylcobalamin product with a generous supply. The amount is excessive for many maintenance users, and flavoring details are incomplete.
How scoring works

Also available as

1 option
1000.00mcg • 90 servings 1000.00mcg • 90 Liquid(s) • 90 servings $14.27 ($0.15 per serving)
$32.47($0.27 per serving)
Vitacost
$ 32.47
Vitacost
$ 32.47
iHerb
$ 32.47
iHerb
$ 32.47
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Analysis

The 5,000 mcg methylcobalamin serving offers deep B12 coverage in an active form. It supports normal nerve, energy, and blood-cell pathways when B12 status is insufficient.

The single-active formula has excellent label clarity and avoids unrelated additions. High potency does not imply a stronger energy effect once B12 needs are met.

The large serving count supports convenient long-term use for people who need this amount. Cherry flavoring details are absent, which matters for users with sensitivities.

Who is it for
  • Adults with defined high B12 needs
  • People who prefer flavored oral delivery
  • Long-term high-potency users
Best for
  • Very high-potency B12 intake
  • Active-form supplementation
  • Large-supply convenience

Pros

  • Bioactive methylcobalamin
  • Very high amount
  • Single active ingredient
  • Large serving count

Cons

  • Excessive for many maintenance users
  • No broader nutrient support
  • Flavoring details are unavailable
  • Not a general stimulant

Warnings

  • The 5,000 mcg amount may be unnecessary when B12 status is adequate
  • Missing cherry flavor ingredients limit sensitivity screening
  • Persistent fatigue needs evaluation beyond escalating B12 intake

Nutrient quality

94 Highest impact

A preferred bioactive B12 form closely fits the intended use. The amount is meaningful, although its suitability depends on whether routine or higher intake is needed.

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Ingredient transparency

84 Highest impact

Active names and amounts are clearly stated, with no hidden proprietary dose. Complete intake directions and a full inactive-ingredient list are not included in the supplied data.

.

Customer satisfaction

71 High impact

Supplied satisfaction metrics indicate a strong result with a meaningful response pool. Detailed experience themes are absent, so recurring complaints and real-world purpose fit remain uncertain.

.

Value for money

100 Highest impact

Serving value appears favorable relative to the disclosed form and amount. The focused formula avoids low-value extras.

.
Report analysis

Goals

Energy
Energy
Impact
Highest effect
A- Goal FitA+ Strength of SupportC- CoverageA+ Formula Quality
Vitamin B12 · 5000 mcg

Methylcobalamin supports energy metabolism and blood formation when vitamin B12 status is inadequate. The 5,000 mcg lozenge provides a very concentrated bioactive dose with clear disclosure.

Most people seeking basic maintenance may not need such a large amount, and extra B12 does not act as a stimulant when status is adequate. The streamlined product nevertheless provides exceptional depth for targeted high-dose B12 use.

Study evidence
Vitamin B12 Disputed 14 studies
General Health
General Health
Impact
High effect
A- Goal FitB Strength of SupportC- CoverageA Formula Quality
Vitamin B12 · 5000 mcg

Bioactive methylcobalamin provides clearly disclosed, focused B12 support. The lozenge format may be practical for people with greater B12 needs.

The 5,000 mcg amount is far beyond ordinary maintenance requirements and will be unnecessary for many users. The formula is very narrow but avoids unrelated active ingredients.

Study evidence
Vitamin B12 Adverse 66 studies
Hair Health
Hair Health
Impact
High effect
C- Goal FitA- Strength of SupportD CoverageA Formula Quality

Methylcobalamin may support hair only when B12 deficiency contributes to shedding. The very high amount offers no proven extra growth benefit for users with adequate status.

The active form, lozenge delivery, and exact disclosure are strong quality features. The single-nutrient design remains narrow and omits iron, zinc, vitamin D, and structural support.

Study evidence
Vitamin B12 Disputed 17 studies
Productivity Boost
Productivity Boost
Impact
High effect
D+ Goal FitA+ Strength of SupportD CoverageB+ Formula Quality
Vitamin B12 · 5000 mcgVitamin B12 · 5000 mcg

A high methylcobalamin amount may improve energy or concentration when vitamin B12 deficiency is present. It is unlikely to act as a general stimulant or nootropic in people with adequate B12 status.

The active form and amount are disclosed with excellent clarity. The narrow formula does not address alertness, stress-related fatigue, or multiple cognitive pathways.

Study evidence
Vitamin B12 Supportive 15 studies
Vitamin B12 No effect 17 studies

Ingredients

IngredientAmount per serving
Vitamin B12 (Methylcobalamin)
 5000 mcg
Gluten Free Adults 18–50 Kosher Dairy Free Vegetarian
Report overview
Vitamin B12 (Methylcobalamin) · 5000 mcg OverallScore100
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

A methylcobalamin lozenge combines a bioactive form with a very high B12 dose. Clear form and amount disclosure make the formula easy to evaluate. The large active amount per serving also produces excellent cost efficiency, though people seeking basic maintenance may not need such a concentrated dose.

View ingredientView products
Loading alternative details
89 Performance

Methyl B-12 1000 mcg & Methyl Folate 400 mcg plus P-5-P Lemon Flavor

Jarrow Formulas
<p>Methylcobalamin, folate, and active vitamin B6 support linked energy and methylation pathways with clearly stated amounts. Compared with the original 5,000 mcg serving, the lower 1,000 mcg amount is less aggressive while retaining methylcobalamin.</p>
87 Performance

Fully Active B12 1500 mcg

Doctor's Best
<p>1,500 mcg of bioactive methylcobalamin provides a focused, easy-to-assess vitamin B12 option. Compared with the original 5,000 mcg serving, the lower 1,500 mcg amount is less aggressive while retaining methylcobalamin.</p>
86 Performance

Methyl B-12 Natural Cherry Flavor

ZHOU
<p>5,000 mcg of bioactive methylcobalamin provides a focused, easy-to-assess vitamin B12 option. The 5,000 mcg amount matches the original dose while using methylcobalamin in a focused formula.</p>
86 Budget

Vitamin B12 2000 mcg

Nutricost
<p>A lower serving cost provides 2,000 mcg of methylcobalamin in a clearly disclosed formula. Compared with the original 5,000 mcg serving, the lower 2,000 mcg amount is less aggressive while retaining methylcobalamin.</p>
86 Budget

Quick Dissolve B-12 Methylcobalamin 2500 mcg

Nature's Bounty
<p>A lower serving cost provides 2,500 mcg of methylcobalamin in a clearly disclosed formula. Compared with the original 5,000 mcg serving, the lower 2,500 mcg amount is less aggressive while retaining methylcobalamin.</p>
87 Budget

B12 Methylcobalamin 1000 mcg

Natural Factors
<p>A lower serving cost provides 1,000 mcg of methylcobalamin in a clearly disclosed formula. Compared with the original 5,000 mcg serving, the lower 1,000 mcg amount is less aggressive while retaining methylcobalamin.</p>
87 Value

Chewable Fully Active B12 Chocolate Mint Flavor 1000 mcg

Doctor's Best
<p>1,000 mcg of methylcobalamin supplies a bioactive form without low-value nutrient extras. The favorable serving cost strengthens value, and compared with the original 5,000 mcg serving, the lower 1,000 mcg amount is less aggressive while retaining methylcobalamin.</p>
85 Value

Vegan B12 2500 mcg

DEVA
<p>2,500 mcg of methylcobalamin supplies a bioactive form without low-value nutrient extras. The favorable serving cost strengthens value, and compared with the original 5,000 mcg serving, the lower 2,500 mcg amount is less aggressive while retaining methylcobalamin.</p>
83 Value

Sublingual Methylcobalamin 1000 mcg

Solgar
<p>1,000 mcg of methylcobalamin supplies a bioactive form without low-value nutrient extras. The favorable serving cost strengthens value, and compared with the original 5,000 mcg serving, the lower 1,000 mcg amount is less aggressive while retaining methylcobalamin.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  2. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  3. Vitamin B12 Supplementation: Is More Always Better?
    Yepes-Calderón M; Doorenbos CSE; Stegmann ME; Touw DJ; Harmsen HJM; Heiner-Fokkema MR; van Spronsen FJ; Corpeleijn E; Bakker SJL · Nutrients · 2026
    Narrative reviewEnergy forVitamin B12
  4. Association of Vitamin B12, Vitamin D, and Thyroid-Stimulating Hormone With Fatigue and Neurologic Symptoms in Patients With Fibromyalgia.
    Munipalli B; Strothers S; Rivera F; Malavet P; Mitri G; Abu Dabrh AM; Dawson NL · Mayo Clinic proceedings. Innovations, quality & outcomes · 2022
    Observational study2,142 participantsEnergy forVitamin B12
  5. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  6. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  7. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  8. Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
    Randomized trial40 participantsGeneral Health forVitamin B12
  9. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
    Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
    Randomized trial90 participantsGeneral Health forVitamin B12
  10. A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
    Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
    Randomized trial98 participantsGeneral Health forVitamin B12
  11. Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
    Randomized trial204 participantsGeneral Health forVitamin B12
  12. The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
    Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
    Clinical trial50 participantsGeneral Health forVitamin B12
  13. Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
    Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
    Case-control study200 participantsHair Health forVitamin B12
  14. Factors Associated with Premature Hair Graying in a Young Indian Population.
    Chakrabarty S; Krishnappa PG; Gowda DG; Hiremath J · International journal of trichology · 2016
    Case-control study74 participantsHair Health forVitamin B12
  15. Risk Factors for Pediatric Alopecia Areata: Clinical and Biochemical Findings from a Case - Control Study.
    İritaş SY · Dermatology practical & conceptual · 2026
    Case-control study600 participantsHair Health forVitamin B12
  16. Hair Loss After Laparoscopic Sleeve Gastrectomy.
    Katsogridaki G; Tzovaras G; Sioka E; Perivoliotis K; Zachari E; Magouliotis D; Tasiopoulou V; Chatedaki C; Zacharoulis D · Obesity surgery · 2019
    Cohort study50 participantsHair Health forVitamin B12
  17. Demographic Characteristics and Association of Serum Vitamin B12, Ferritin and Thyroid Function with Premature Canities in Indian Patients from an Urban Skin Clinic of North India: A Retrospective Analysis of 71 Cases.
    Sonthalia S; Priya A; Tobin DJ · Indian journal of dermatology · 2022
    Cross-sectional study71 participantsHair Health forVitamin B12
  18. Effects of Folic Acid and Vitamin B12, Alone and in Combination on Cognitive Function and Inflammatory Factors in the Elderly with Mild Cognitive Impairment: A Single-blind Experimental Design.
    Ma F; Zhou X; Li Q; Zhao J; Song A; An P; Du Y; Xu W; Huang G · Current Alzheimer research · 2020
    Randomized trial240 participantsProductivity Boost forVitamin B12
  19. Effects of Physical Activity and Micronutrients on Cognitive Performance in Children Aged 6 to 11 Years: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Meli AM; Ali A; Mhd Jalil AM; Mohd Yusof H; Tan MMC · Medicina (Kaunas, Lithuania) · 2022
    Meta-analysisProductivity Boost forVitamin B12
  20. Cognitive function in an elderly population: interaction between vitamin B12 status, depression, and apolipoprotein E ε4: the Hordaland Homocysteine Study.
    Vogiatzoglou A; Smith AD; Nurk E; Drevon CA; Ueland PM; Vollset SE; Nygaard HA; Engedal K; Tell GS; Refsum H · Psychosomatic medicine · 2013
    Cross-sectional study1,935 participantsProductivity Boost forVitamin B12
  21. Cognitive profile and inflammatory markers in children and adolescents with specific learning disorder: a cross-sectional study.
    Balatacı U; Ay B · Frontiers in pediatrics · 2026
    Case-control study108 participantsProductivity Boost forVitamin B12
  22. Association between vitamin B12 levels and cognitive impairment in older adults.
    Aguilar-Navarro SG; Carbajal-Silva JC; Palacios-Hernández MGI; Gutiérrez-Gutierrez LA; Ávila-Funes JA; Mimenza-Alvarado AJ · Gaceta medica de Mexico · 2023
    Cross-sectional study241 participantsProductivity Boost forVitamin B12
  23. Effects of vitamin B12 on performance and circadian rhythm in normal subjects.
    Mayer G; Kröger M; Meier-Ewert K · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 1997
    Randomized trial20 participantsProductivity Boost forVitamin B12
  24. Prenatal vitamin B12 status and cognitive functioning in children at 4 years of age: The ECLIPSES Study.
    Cruz-Rodríguez J; Canals-Sans J; Hernández-Martínez C; Voltas-Moreso N; Arija V · Maternal & child nutrition · 2023
    Cohort study249 participantsProductivity Boost forVitamin B12
  25. Dietary intakes and biomarker patterns of folate, vitamin B6, and vitamin B12 can be associated with cognitive impairment by hypermethylation of redox-related genes NUDT15 and TXNRD1.
    An Y; Feng L; Zhang X; Wang Y; Wang Y; Tao L; Qin Z; Xiao R · Clinical epigenetics · 2020
    Cohort study2,533 participantsProductivity Boost forVitamin B12
  26. Homocysteine, folate, and vitamins B6 and B12 blood levels in relation to cognitive performance: the Maine-Syracuse study.
    Elias MF; Robbins MA; Budge MM; Elias PK; Brennan SL; Johnston C; Nagy Z; Bates CJ · Psychosomatic medicine · 2008
    Cross-sectional study812 participantsProductivity Boost forVitamin B12