Product Image

Super C Complex

NaturesPlus
4.7
★ ★ ★ ★ ★
(4660 ratings)
Rutin 100 mg
Vitamin C 1000 mg
Acerola 50 mg
Flavonoid (mixture) 500 mg
Product Image
Score74
A potent capsule-based vitamin C and flavonoid blend with good rutin sourcing, but basic delivery and unclear duplicate flavonoid labeling reduce transparency.
How scoring works
Quantity:180 Capsule(s) • (90 servings)
Goals:
Immunity
Anti-Inflammatory Support
General Health
Skin Health

Score 74

A potent capsule-based vitamin C and flavonoid blend with good rutin sourcing, but basic delivery and unclear duplicate flavonoid labeling reduce transparency.
How scoring works
$37.36($0.41 per serving)
iHerb
$ 37.36
Vitacost
$ 37.36
Report prices

Analysis

A high vitamin C amount supports antioxidant protection, collagen formation, and normal immune function. Large citrus bioflavonoid entries plus rutin and hesperidin provide substantial companion compounds.

Sophora japonica gives the rutin a useful source identity, while rose hip is also botanically named. The two large bioflavonoid entries are not clearly reconciled, and acerola lacks standardization or plant-part details.

The two-capsule serving fits people who prefer capsules and tolerate ordinary ascorbic acid. It remains a focused antioxidant formula and does not cover macular pigments, structural skin ingredients, or direct lipid-based inflammatory pathways.

Who is it for
  • Adults preferring capsules over tablets
  • Users seeking substantial vitamin C and flavonoids
  • People comfortable with a two-capsule serving
Best for
  • High-potency antioxidant support
  • Normal immune function
  • Collagen cofactor support

Pros

  • Substantial vitamin C and flavonoid amounts
  • Rutin botanical source is stated
  • Major active weights are disclosed

Cons

  • Unbuffered ascorbic acid
  • Repeated bioflavonoid entries are unclear
  • Acerola is low and unstandardized

Warnings

  • The high vitamin C amount may cause digestive upset or loose stools
  • People prone to oxalate kidney stones should obtain individualized guidance
  • Check other supplements to avoid redundant high-dose vitamin C

Nutrient quality

83 Highest impact

Standard ascorbic acid is effective but lacks buffering or enhanced delivery. Vitamin C and citrus bioflavonoids are substantial, with useful rutin and hesperidin support.

.

Ingredient transparency

76 High impact

All ingredient weights are shown, but repeated bioflavonoid entries make the total composition less clear. The supplied data does not include a complete inactive ingredient list.

.

Customer satisfaction

71 High impact

The aggregate satisfaction measure is strong enough to support a favorable first impression. Missing feedback themes leave repeat complaints and purpose fit uncertain despite adequate volume.

.

Value for money

64 Moderate impact

The price is somewhat high for standard unbuffered vitamin C. Each serving costs more than many comparable basic vitamin C formulas.

.
Report analysis

Goals

Immunity
Impact
Highest effect
A+ Goal FitA Strength of SupportB+ CoverageA Formula Quality
Vitamin C · 1000 mg

A 1,000 mg vitamin C serving directly supports immune-cell function, antioxidant protection, and epithelial barriers. Citrus flavonoids, rutin, hesperidin, rose hip, and acerola adds useful formulation context around the core dose.

The formula provides strong depth for one major immune pathway rather than broad cellular and mucosal coverage. Its supporting flavonoids are relevant, although their specific immune contribution is less certain than vitamin C.

Study evidence
Vitamin C Supportive 53 studies
Anti-Inflammatory Support
Impact
Highest effect
B- Goal FitB+ Strength of SupportB+ CoverageB+ Formula Quality
Vitamin C · 1000 mg

Vitamin C, citrus bioflavonoids, rutin, and hesperidin provide broad antioxidant and vascular-signaling support. The flavonoid amounts are more substantial than token additions, although direct systemic anti-inflammatory evidence remains moderate.

All main actives are individually disclosed, and their roles are complementary. The formula has useful antioxidant breadth but does not match the direct inflammatory-mediator effects of omega-3 fats or curcumin.

Study evidence
Rutin Supportive 6 studies
Vitamin C Supportive 50 studies
General Health
Impact
High effect
B Goal FitA- Strength of SupportC CoverageB Formula Quality
Vitamin C · 1000 mg

The formula pairs a substantial vitamin C amount with citrus flavonoids, rutin, rose hips, and acerola for focused antioxidant support. Vitamin C provides the strongest established contribution, while the supporting compounds may broaden antioxidant activity.

Several secondary ingredients have less certain general-health value than the core vitamin. The vitamin C amount may cause stomach upset or diarrhea, and sustained high intake may be unsuitable for people prone to oxalate kidney stones.

Study evidence
Vitamin C Supportive 56 studies
Skin Health
Impact
High effect
C- Goal FitB+ Strength of SupportC- CoverageB+ Formula Quality
Vitamin C · 1000 mg

Vitamin C directly supports normal collagen formation, while citrus bioflavonoids, rutin, and hesperidin add related antioxidant compounds. The vitamin C amount and major flavonoid weights are substantial.

The formula still does not provide collagen, ceramides, hyaluronic acid, or barrier lipids. Several overlapping flavonoids add limited pathway breadth because they largely serve the same antioxidant role.

Study evidence
Vitamin C Supportive 53 studies
Vision Support
Impact
Moderate effect
D Goal FitB+ Strength of SupportD CoverageC+ Formula Quality
Vitamin C · 1000 mg

Vitamin C supports antioxidant defenses in ocular tissues, while rutin and citrus flavonoids provide secondary vascular and antioxidant support. The formula lacks macular carotenoids, zinc, copper, vitamin E, and omega-3 structural lipids.

All major amounts are clearly disclosed and vitamin C is supplied generously. Repeated flavonoid ingredients broaden one antioxidant pathway rather than creating comprehensive vision support.

Study evidence
Rutin Not classified 1 study
Vitamin C Disputed 24 studies

Ingredients

IngredientAmount per serving
Vitamin C (Ascorbic Acid)
1000 mg
Bioflavonoids (Citrus limon, Sweet Orange)
500 mg
Rutin (Sophora japonica)
100 mg
Hesperidin Complex (Citrus sinensis)
100 mg
Rose Hip (Rosa canina)
100 mg
Acerola
50 mg
Gluten Free Adults 18–50 Vegan Dairy Free No Allergies Vegetarian
Report overview
B- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyB Value

Sophora japonica gives the rutin a clearly preferred botanical source. The exact amount offers moderate support, although it remains below the targeted range and lacks purity details. Cost efficiency is good for the rutin supplied, with two capsules required per serving.

F Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value

The 1,000 mg dose is well targeted and accompanied by substantial citrus compounds. Standard ascorbic acid offers no buffering or enhanced delivery, and the repeated bioflavonoid entries make the supporting blend somewhat unclear. Cost efficiency is slightly weaker than average for a basic form.

Acerola · 50 mg OverallScore26
F Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyF Value

Acerola lacks a concentration ratio, vitamin C yield, scientific name, and plant-part detail. Synthetic ascorbic acid supplies most of the vitamin C, making acerola a secondary ingredient. The 50 mg dose is low and offers poor acerola-specific value.

Loading alternative details
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  2. Effect of Vitamin C Supplements on Respiratory Tract Infections: A Systematic Review and Meta-Analysis.
    Keya TA; Leela A; Fernandez K; Habib N; Rashid M · Current reviews in clinical and experimental pharmacology · 2022
    Meta-analysis10 studies pooledImmunity forVitamin C
  3. Vitamin C supplementation and salivary immune function following exercise-heat stress.
    Carrillo AE; Murphy RJ; Cheung SS · International journal of sports physiology and performance · 2009
    Randomized trial12 participantsImmunity forVitamin C
  4. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  5. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  6. Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage.
    Fitzpatrick RE; Rostan EF · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2002
    Non-randomized trial10 participantsSkin Health forVitamin C
  7. Vitamin C and postoperative outcomes following mandibular third molar extraction: a randomized split-mouth study.
    Demirel M; Aktas A; Kizil M; Yalcin N · Oral surgery, oral medicine, oral pathology and oral radiology · 2026
    Randomized trial56 participantsSkin Health forVitamin C
  8. The effects of rutin flavonoid supplement on glycemic status, lipid profile, atherogenic index of plasma, brain-derived neurotrophic factor (BDNF), some serum inflammatory, and oxidative stress factors in patients with type 2 diabetes mellitus: A double-blind, placebo-controlled trial.
    Bazyar H; Moradi L; Zaman F; Zare Javid A · Phytotherapy research : PTR · 2023
    Randomized trial50 participantsAnti-Inflammatory Support forRutin
  9. Rutin ameliorates inflammation and improves metabolic function: A comprehensive analysis of scientific literature.
    Muvhulawa N; Dludla PV; Ziqubu K; Mthembu SXH; Mthiyane F; Nkambule BB; Mazibuko-Mbeje SE · Pharmacological research · 2022
    Systematic reviewAnti-Inflammatory Support forRutin
  10. Rutin-loaded chitosan microspheres: Characterization and evaluation of the anti-inflammatory activity.
    Cosco D; Failla P; Costa N; Pullano S; Fiorillo A; Mollace V; Fresta M; Paolino D · Carbohydrate polymers · 2018
    OtherAnti-Inflammatory Support forRutin
  11. Oral enzyme combination therapy reduces systemic inflammation, urinary CTXII and pain in knee osteoarthritis: a proof-of-mechanism, randomised, crossover, double-blind, placebo-controlled trial.
    Henrotin Y; Pap T; Lieten S; Badot V; Dubuc JE; Urbin-Choffray D; von Eynatten M; Johansen OE; Rau S; Brabants K · RMD open · 2025
    Randomized trial45 participantsAnti-Inflammatory Support forRutin
  12. The Impact of the Combination of Proteolytic Enzyme and Rutin on the Post-operative Management of Inflammation: A Randomized, Controlled, Double-Blind, Comparative Clinical Trial
    Rathi PC, Rathi CL, Risbud SP, Ganu GP · Cureus · 2024
    Randomized trial65 participantsAnti-Inflammatory Support forRutin
  13. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  14. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  15. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  16. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  17. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  18. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  19. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  20. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  21. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  22. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  23. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  24. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  25. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  26. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  27. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  28. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  29. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  30. A randomized, double-masked study on the treatment of retinal vein occlusion with troxerutin
    Glacet-Bernard A, Coscas G, Chabanel A, Zourdani A, Lelong F, Samama MM · American Journal of Ophthalmology · 1994
    Randomized trial53 participantsVision Support forRutin
  31. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  32. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  33. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  34. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C
  35. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C