Product Image

Vitamin K2 100 mcg

4.8
★ ★ ★ ★ ★
(71 ratings)
Vitamin K 100 mcg
Product Image
Score84

A simple MK-7 supplement provides focused vitamin K2 support, with supplied record lists MK-7 and natto extract at the same amount, so the intended total needs label confirmation as the main trade-off.

How scoring works
Capsule
Quantity:100 Capsule(s) • (100 servings)
Goals:
General Health
Heart Health
Cardiovascular Support
Anti-Aging
Bone Health

Score 84

A simple MK-7 supplement provides focused vitamin K2 support, with supplied record lists MK-7 and natto extract at the same amount, so the intended total needs label confirmation as the main trade-off.

How scoring works
$25.20($0.25 per serving)
Vitacost
$ 25.23
iHerb
$ 25.20
Daily Vita
$ 25.20
Report prices

Analysis

MK-7 is a long-acting vitamin K2 form that supports activation of proteins involved in bone mineral use and calcium handling. The focused formula is easier to assess than a large multinutrient blend.

The a practical daily amount is clearly aligned with dedicated K2 supplementation. The long supply supports convenient routine use, although it does not supply vitamin D, calcium, or magnesium for broader bone support.

The supplied record lists MK-7 and natto extract at the same amount, so the intended total needs label confirmation. Vitamin K still requires careful coordination with medicines designed to block its action.

Who is it for
  • Adults seeking standalone MK-7
  • People who already obtain vitamin D separately
  • Users who prefer a capsule
Best for
  • Standalone vitamin K2 use
  • Customizing a separate bone-nutrient routine
  • Long-acting MK-7 supplementation

Pros

  • MK-7 form is identified
  • a practical daily amount
  • Simple single-active formula
  • The long supply supports convenient routine use

Cons

  • No vitamin D included
  • No calcium or magnesium included
  • supplied record lists MK-7 and natto extract at the same amount, so the intended total needs label confirmation

Warnings

  • Vitamin K can oppose warfarin and related vitamin-K-antagonist medicines; use requires consistent medical guidance.
  • People with a diagnosed bleeding or clotting disorder should not self-prescribe vitamin K2.
  • Standalone K2 should not be used to correct a diagnosed vitamin K deficiency without identifying the cause.

Nutrient quality

93 Highest impact

The focused active formula contains little apparent low-value padding. The ingredients generally fit the intended use despite a form or scope limitation.

Ingredient transparency

69 High impact

No named proprietary blend hides the core nutrients, though duplicated entries reduce clarity. A complete list of inactive ingredients is not supplied.

Customer satisfaction

86 Highest impact

The aggregate customer rating is strong. The modest review count limits confidence in the aggregate rating.

Value for money

90 Highest impact

The price is supported mainly by useful core actives rather than low-value extras. The formula quality broadly supports its value, with a notable dosing or disclosure trade-off.

Report analysis

Goals

General Health
General Health
Impact
Highest effect
A- Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Vitamin K · 100 mcg

MK-7 is a relevant vitamin K2 form for normal calcium handling and bone support. The clearly stated amount is well suited to focused daily use.

Natto sourcing adds useful identity, though the capsule lacks a disclosed lipid carrier or all-trans quality marker. Vitamin K2 can counteract warfarin and related coumarin anticoagulants, so people using those medicines need prescriber guidance.

Study evidence
Vitamin K Supportive 34 studies
Heart Health
Heart Health
Impact
Highest effect
B Goal FitA Strength of SupportC- CoverageA Formula Quality
Vitamin K · 100 mcg

MK-7 provides focused support for normal calcium handling in vascular tissue. The formula targets one relevant pathway and does not offer broad cardiovascular coverage.

The subtype and amount are clearly disclosed and align well with common K2 supplementation. Vitamin K2 can interfere with warfarin and other vitamin K antagonist therapy, so that use requires clinician-guided consistency.

Study evidence
Vitamin K Mixed 62 studies
Cardiovascular Support
Cardiovascular Support
Impact
High effect
B Goal FitA- Strength of SupportD+ CoverageA Formula Quality
Vitamin K · 100 mcg

One hundred micrograms of vitamin K2 as MK-7 provides focused support for calcium handling and arterial health. Natto sourcing is disclosed, though no all-trans or branded purity standard is stated.

The simple capsule gives the selected pathway useful depth without adding low-dose extras. Vitamin K2 can counteract warfarin and related vitamin-K-antagonist medicines, so users of those drugs need prescriber-guided intake consistency.

Study evidence
Vitamin K Supportive 40 studies
Anti-Aging
Anti-Aging
Impact
High effect
C+ Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Vitamin K · 100 mcg

MK-7 vitamin K2 supports calcium handling in arteries and bones, a relevant pathway for maintaining function with age. The 100 mcg amount is clinically aligned and clearly disclosed.

The dry capsule lacks fat-intake guidance and does not identify a branded or all-trans source. A single vitamin K2 pathway leaves mitochondrial, inflammatory, neurological, and glycation mechanisms unaddressed.

Study evidence
Vitamin K Supportive 27 studies
Bone Health
Bone Health
Impact
High effect
B- Goal FitB+ Strength of SupportC CoverageB Formula Quality
Vitamin K · 100 mcg

Vitamin K provides a clear and meaningful foundation for bone support. The main relevant amounts appear substantial enough to contribute in practice.

Coverage is concentrated on vitamin-guided mineral handling. The focused design leaves other major bone pathways uncovered.

Study evidence
Vitamin K Supportive 78 studies

Ingredients

IngredientAmount per serving
Vitamin K2 (Menaquinone-7, Natto Extract)
 100 mcg
Gluten Free Adults 18–50 Vegan Kosher Sugar Free Women No Allergies Vegetarian
Report overview
Vitamin K (Menaquinone-7, Natto Extract) · 100 mcg OverallScore87
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

A clinical amount of MK-7 provides focused vitamin K2 support with clear subtype disclosure. Natto sourcing is shown, though no branded or all-trans quality claim appears and the dry capsule lacks lipid guidance. Efficient cost and a focused formula make it a strong value.

View ingredientView products
Loading alternative details
86 Performance

Liquid D-3 & MK-7

NOW
<p>Liquid delivery combines MK-7 with a substantial vitamin D3 amount and provides flexible dosing with strong bone- and heart-goal alignment. Added vitamin D broadens the formula but may be unnecessary when only standalone K2 is wanted. Vitamin K requires clinician-directed consistency with warfarin-type medicines.</p>
87 Performance

Vitamin D3 25 mcg (1000 IU) & K2 120 mcg

Natural Factors
<p>Moderate vitamin D3 and MK-7 create a balanced maintenance pairing in a softgel, with only minor ambiguity from duplicate K2 source entries. Added vitamin D broadens the formula but may be unnecessary when only standalone K2 is wanted. Vitamin K requires clinician-directed consistency with warfarin-type medicines.</p>
84 Performance

D3 + K2

Nature Made
<p>All-trans MK-7 and vitamin D3 use clearly defined forms in a focused softgel, improving active-form clarity. Added vitamin D broadens the formula but may be unnecessary when only standalone K2 is wanted. Vitamin K requires clinician-directed consistency with warfarin-type medicines.</p>
88 Budget

Vitamin K2 MK-7 100 mcg

Nutricost
<p>At a lower serving cost, a clearly stated MK-7 amount creates a simple, easy-to-assess vitamin K2 option, although the dry capsule has no stated lipid carrier. It preserves the original standalone K2 purpose without adding unnecessary vitamin D. Vitamin K can oppose warfarin-type anticoagulants.</p>
87 Budget

MK-7 Vitamin K-2 100 mcg

NOW
<p>At a lower serving cost, a meaningful long-acting MK-7 amount provides focused vitamin K2 support with a simple active formula. It preserves the original standalone K2 purpose without adding unnecessary vitamin D. Vitamin K can oppose warfarin-type anticoagulants.</p>
85 Budget

Vitamin K2 MenaQ7 100 mcg

AN Amazing Nutrition Amazing Formulas
<p>At a lower serving cost, natto-derived MenaQ7 provides a clearly identified long-acting vitamin K2 form in a focused formula. It preserves the original standalone K2 purpose without adding unnecessary vitamin D. Vitamin K can oppose warfarin-type anticoagulants.</p>
86 Value

Vitamin K2 100 mcg + Vitamin D3 125 mcg

Nutricost
<p>MK-7 and vitamin D3 provide a fully disclosed combination at very favorable serving value, but the vitamin D amount is concentrated. The standalone options avoid adding vitamin D, while combination choices are useful only when vitamin D is also wanted. Vitamin K can reduce the effect of warfarin-type anticoagulants.</p>
86 Value

Vitamins D3 2500 IU (62.5 mcg) & K2 120 mcg

NaturesPlus
<p>MK-7 and a substantial vitamin D3 amount provide focused bone and cardiovascular support at a low serving cost, though the dry tablet lacks a lipid carrier. The standalone options avoid adding vitamin D, while combination choices are useful only when vitamin D is also wanted. Vitamin K can reduce the effect of warfarin-type anticoagulants.</p>
86 Value

Natural Vitamin K2 MK-7 with MenaQ7 100 mcg

Doctor's Best
<p>Branded MenaQ7 provides a meaningful long-acting K2 amount with clear active disclosure and good serving value. The standalone options avoid adding vitamin D, while combination choices are useful only when vitamin D is also wanted. Vitamin K can reduce the effect of warfarin-type anticoagulants.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsHeart Health Cardiovascular Support forVitamin K
  2. Vitamin K Supplementation for the Prevention of Cardiovascular Disease: Where Is the Evidence? A Systematic Review of Controlled Trials.
    Vlasschaert C; Goss CJ; Pilkey NG; McKeown S; Holden RM · Nutrients · 2021
    Systematic review9 studies pooledHeart Health forVitamin K
  3. Vitamin K Supplementation to Improve Vascular Stiffness in CKD: The K4Kidneys Randomized Controlled Trial.
    Witham MD; Lees JS; White M; Band M; Bell S; Chantler DJ; Ford I; Fulton RL; Kennedy G; Littleford RC; McCrea IV; McGlynn D; Panarelli M; Ralston MR; Rutherford E; Severn A; Thomson N; Traynor JP; Struthers AD; Wetherall K; Mark PB · Journal of the American Society of Nephrology : JASN · 2021
    Randomized trial159 participantsHeart Health forVitamin K
  4. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  5. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials.
    Huang ZB; Wan SL; Lu YJ; Ning L; Liu C; Fan SW · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Meta-analysis6,759 participants19 studies pooledBone Health forVitamin K
  6. Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
    Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
    Randomized trial771 participantsBone Health forVitamin K
  7. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support Heart Health forVitamin K
  8. The relationship between vitamin K and peripheral arterial disease.
    Vissers LET; Dalmeijer GW; Boer JMA; Verschuren WMM; van der Schouw YT; Beulens JWJ · Atherosclerosis · 2017
    Cohort study36,629 participantsCardiovascular Support forVitamin K
  9. Interventions to Attenuate Cardiovascular Calcification Progression: A Systematic Review of Randomized Clinical Trials.
    Murali S; Smith ER; Tiong MK; Tan SJ; Toussaint ND · Journal of the American Heart Association · 2024
    Systematic review9,901 participants49 studies pooledCardiovascular Support forVitamin K
  10. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledAnti-Aging General Health forVitamin K
  11. Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
    Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
    Randomized trial30 participantsAnti-Aging forVitamin K
  12. Vitamin K status and cognitive function in healthy older adults.
    Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
    Cross-sectional study320 participantsAnti-Aging forVitamin K
  13. High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
    Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
    Cohort study644 participantsAnti-Aging forVitamin K
  14. Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
    Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
    Cross-sectional study85 participantsAnti-Aging forVitamin K
  15. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  16. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  17. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  18. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  19. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  20. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  21. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsCardiovascular Support Heart Health forVitamin K
  22. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  23. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  24. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  25. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K
  26. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K