Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Differential cognitive effects of energy drink ingredients: caffeine, taurine, and glucose.
Giles GE; Mahoney CR; Brunyé TT; Gardony AL; Taylor HA; Kanarek RB · Pharmacology, biochemistry, and behavior · 2013
Randomized trial48 participantsflagEnergy forscienceCaffeine
- Caffeine administration at night during extended wakefulness effectively mitigates performance impairment but not subjective assessments of fatigue and sleepiness.
Paech GM; Banks S; Pajcin M; Grant C; Johnson K; Kamimori GH; Vedova CB · Pharmacology, biochemistry, and behavior · 2017
Randomized trial24 participantsflagEnergy forscienceCaffeine
- Caffeine Supplementation and Physical Performance, Muscle Damage and Perception of Fatigue in Soccer Players: A Systematic Review.
Mielgo-Ayuso J; Calleja-Gonzalez J; Del Coso J; Urdampilleta A; León-Guereño P; Fernández-Lázaro D · Nutrients · 2019
Systematic review17 participants17 studies pooledflagEnergy forscienceCaffeine
- A critical review of caffeine withdrawal: empirical validation of symptoms and signs, incidence, severity, and associated features.
Juliano LM; Griffiths RR · Psychopharmacology · 2005
Systematic review66 studies pooledflagEnergy forscienceCaffeine
- Effect of caffeine ingestion on cycling performance: a systematic review and meta-analysis.
Wu J; Xu K; Yin M; Ding X; Wang T; Zhang Q; Wu X; Xiao N · Frontiers in nutrition · 2026
Meta-analysis226 participants20 studies pooledflagFitness forscienceCaffeine
- Acute Effects of Caffeine Supplementation on Physical Performance, Physiological Responses, Perceived Exertion, and Technical-Tactical Skills in Combat Sports: A Systematic Review and Meta-Analysis.
Delleli S; Ouergui I; Messaoudi H; Trabelsi K; Ammar A; Glenn JM; Chtourou H · Nutrients · 2022
Meta-analysis26 studies pooledflagFitness forscienceCaffeine
- No effects of caffeine on cycling to exhaustion and perceptual responses in non-caffeine-restricted subjects.
Weippert M; Behrens M; Schlegel M; Schröder T; Tillmann M; Rühe N; Römer R; Mau-Möller A; Bruhn S · Journal of the International Society of Sports Nutrition · 2025
Randomized trial56 participantsflagFitness forscienceCaffeine
- Effects of modafinil and caffeine on night-time vigilance of air force crewmembers: A randomized controlled trial.
Wingelaar-Jagt YQ; Bottenheft C; Riedel WJ; Ramaekers JG · Journal of psychopharmacology (Oxford, England) · 2023
Randomized trial32 participantsflagMental Focus forscienceCaffeine
- Using coffee to compensate for poor sleep: Impact on vigilance and implications for workplace performance.
Anderson JR; Hagerdorn PL; Gunstad J; Spitznagel MB · Applied ergonomics · 2018
Randomized trial69 participantsflagMental Focus forscienceCaffeine
- Physiological and cognitive responses to caffeine during repeated, high-intensity exercise.
Crowe MJ; Leicht AS; Spinks WL · International journal of sport nutrition and exercise metabolism · 2007
Randomized trial17 participantsflagMental Focus forscienceCaffeine
- Caffeinated Coffee and Tea Consumption, Genetic Variation and Cognitive Function in the UK Biobank.
Cornelis MC; Weintraub S; Morris MC · The Journal of nutrition · 2020
Cross-sectional study445,786 participantsflagMental Focus forscienceCaffeine
- Systematic review and meta-analysis of the efficacy and safety of chromium supplementation in diabetes.
Suksomboon N; Poolsup N; Yuwanakorn A · Journal of clinical pharmacy and therapeutics · 2015
Meta-analysis25 studies pooledflagMetabolism Boost forscienceChromium
- The Effects of Supplementation with Chromium on Insulin Resistance Indices in Women with Polycystic Ovarian Syndrome: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Heshmati J; Omani-Samani R; Vesali S; Maroufizadeh S; Rezaeinejad M; Razavi M; Sepidarkish M · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2018
Meta-analysis268 participants5 studies pooledflagMetabolism Boost forscienceChromium
- Improved meta-analytic methods show no effect of chromium supplements on fasting glucose.
Bailey CH · Biological trace element research · 2014
Meta-analysis809 participants16 studies pooledflagMetabolism Boost forscienceChromium
- Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity.
Masharani U; Gjerde C; McCoy S; Maddux BA; Hessler D; Goldfine ID; Youngren JF · BMC endocrine disorders · 2013
Randomized trial31 participantsflagMetabolism Boost forscienceChromium
- Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine.
Haskell CF; Kennedy DO; Wesnes KA; Scholey AB · Psychopharmacology · 2005
Randomized trial48 participantsflagEnergy forscienceCaffeine
- Caffeine-containing energy drink improves physical performance of elite rugby players during a simulated match.
Del Coso J; Ramírez JA; Muñoz G; Portillo J; Gonzalez-Millán C; Muñoz V; Barbero-Álvarez JC; Muñoz-Guerra J · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2016
Randomized trial26 participantsflagEnergy forscienceCaffeine
- Does Single or Combined Caffeine and Taurine Supplementation Improve Athletic and Cognitive Performance without Affecting Fatigue Level in Elite Boxers? A Double-Blind, Placebo-Controlled Study.
Ozan M; Buzdagli Y; Eyipinar CD; Baygutalp NK; Yüce N; Oget F; Kan E; Baygutalp F · Nutrients · 2022
Randomized trial20 participantsflagEnergy forscienceCaffeine
- Trait Energy and Fatigue Modify the Effects of Caffeine on Mood, Cognitive and Fine-Motor Task Performance: A Post-Hoc Study.
Fuller DT; Smith ML; Boolani A · Nutrients · 2021
Randomized trialflagEnergy forscienceCaffeine
- Effects of Caffeine Intake on Endurance Running Performance and Time to Exhaustion: A Systematic Review and Meta-Analysis.
Wang Z; Qiu B; Gao J; Del Coso J · Nutrients · 2023
Meta-analysis254 participants21 studies pooledflagFitness forscienceCaffeine
- Acute Effects of Caffeine Supplementation on Movement Velocity in Resistance Exercise: A Systematic Review and Meta-analysis.
Raya-González J; Rendo-Urteaga T; Domínguez R; Castillo D; Rodríguez-Fernández A; Grgic J · Sports medicine (Auckland, N.Z.) · 2021
Meta-analysis12 studies pooledflagFitness forscienceCaffeine
- Sex Differences in the Ergogenic Response of Acute Caffeine Intake on Muscular Strength, Power and Endurance Performance in Resistance-Trained Individuals: A Randomized Controlled Trial.
Montalvo-Alonso JJ; Ferragut C; Del Val-Manzano M; Valadés D; Roberts J; Pérez-López A · Nutrients · 2024
Randomized trial76 participantsflagFitness forscienceCaffeine
- Can I Have My Coffee and Drink It? A Systematic Review and Meta-analysis to Determine Whether Habitual Caffeine Consumption Affects the Ergogenic Effect of Caffeine.
Carvalho A; Marticorena FM; Grecco BH; Barreto G; Saunders B · Sports medicine (Auckland, N.Z.) · 2022
Meta-analysis60 studies pooledflagFitness forscienceCaffeine
- A systematic review and meta-analysis of propionyl-L-carnitine effects on exercise performance in patients with claudication.
Brass EP; Koster D; Hiatt WR; Amato A · Vascular medicine (London, England) · 2013
Meta-analysis13 studies pooledflagFitness forscienceL-Carnitine
- Oral acetyl-L-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study.
Malaguarnera M; Vacante M; Giordano M; Pennisi G; Bella R; Rampello L; Malaguarnera M; Li Volti G; Galvano F · The American journal of clinical nutrition · 2011
Randomized trial121 participantsflagFitness forscienceL-Carnitine
- Prolonged oral L-carnitine substitution increases bicycle ergometer performance in patients with severe, ischemically induced cardiac insufficiency.
Löster H; Miehe K; Punzel M; Stiller O; Pankau H; Schauer J · Cardiovascular drugs and therapy · 2000
Randomized trial41 participantsflagFitness forscienceL-Carnitine
- L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial.
Malaguarnera M; Cammalleri L; Gargante MP; Vacante M; Colonna V; Motta M · The American journal of clinical nutrition · 2008
Randomized trial66 participantsflagFitness forscienceL-Carnitine
- Effects of nine weeks L-Carnitine supplementation on exercise performance, anaerobic power, and exercise-induced oxidative stress in resistance-trained males.
Koozehchian MS; Daneshfar A; Fallah E; Agha-Alinejad H; Samadi M; Kaviani M; Kaveh B M; Jung YP; Sablouei MH; Moradi N; Earnest CP; Chandler TJ; Kreider RB · Journal of exercise nutrition & biochemistry · 2020
Randomized trial23 participantsflagFitness forscienceL-Carnitine
- Acute effects of caffeine on attention: a comparison of non-consumers and withdrawn consumers.
Smith AP; Christopher G; Sutherland D · Journal of psychopharmacology (Oxford, England) · 2013
Randomized trial70 participantsflagMental Focus forscienceCaffeine
- Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.
Wesensten NJ; Killgore WD; Balkin TJ · Journal of sleep research · 2006
Randomized trial48 participantsflagMental Focus forscienceCaffeine
- Effects of caffeine on mood and performance: a study of realistic consumption.
Brice CF; Smith AP · Psychopharmacology · 2003
Clinical trial24 participantsflagMental Focus forscienceCaffeine
- Effects of caffeine or diphenhydramine on visual vigilance.
Fine BJ; Kobrick JL; Lieberman HR; Marlowe B; Riley RH; Tharion WJ · Psychopharmacology · 1995
Randomized trial24 participantsflagMental Focus forscienceCaffeine
- A Randomized Study to Examine the Ability of a Caffeine-Based Energy Drink to Impact Energy Expenditure, Fat Oxidation, and Cognitive Performance.
Krieger J; Schrautemeier A; Hagele A; Gaige C; Mennemeyer O; Tolbert S; Iannotti J; Kerksick C; Noonan C; Mumford P · Nutrients · 2025
Randomized trial60 participantsflagMetabolism Boost forscienceCaffeine
- Oolong tea increases metabolic rate and fat oxidation in men.
Rumpler W; Seale J; Clevidence B; Judd J; Wiley E; Yamamoto S; Komatsu T; Sawaki T; Ishikura Y; Hosoda K · The Journal of nutrition · 2001
Randomized trial12 participantsflagMetabolism Boost forscienceCaffeine
- Effect of caffeine intake on fat oxidation rate during exercise: is there a dose-response effect?
Gutiérrez-Hellín J; Aguilar-Navarro M; Ruiz-Moreno C; Muñoz A; Varillas-Delgado D; Amaro-Gahete FJ; Del Coso J · European journal of nutrition · 2023
Randomized trial18 participantsflagMetabolism Boost forscienceCaffeine
- Comparison of changes in energy expenditure and body temperatures after caffeine consumption.
Koot P; Deurenberg P · Annals of nutrition & metabolism · 1995
Randomized trial12 participantsflagMetabolism Boost forscienceCaffeine
- Caffeine Increases Work Done above Critical Power, but Not Anaerobic Work.
Silveira R; Andrade-Souza VA; Arcoverde L; Tomazini F; Sansonio A; Bishop DJ; Bertuzzi R; Lima-Silva AE · Medicine and science in sports and exercise · 2018
Randomized trial9 participantsflagMetabolism Boost forscienceCaffeine
- Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes.
Anderson RA; Cheng N; Bryden NA; Polansky MM; Cheng N; Chi J; Feng J · Diabetes · 1997
Randomized trial180 participantsflagMetabolism Boost forscienceChromium
- Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Jamilian M; Asemi Z · Annals of nutrition & metabolism · 2016
Randomized trial64 participantsflagMetabolism Boost forscienceChromium
- A Comprehensive insight into the effect of chromium supplementation on oxidative stress indices in diabetes mellitus: A systematic review.
Kooshki F; Tutunchi H; Vajdi M; Karimi A; Niazkar HR; Shoorei H; Pourghassem Gargari B · Clinical and experimental pharmacology & physiology · 2024
Systematic review33 studies pooledflagMetabolism Boost forscienceChromium
- Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
Meta-analysis2,362 participants41 studies pooledflagMetabolism Boost forscienceChromium
- [Chromium supplementation in patients with type 2 diabetes and high risk of type 2 diabetes: a meta-analysis of randomized controlled trials].
San Mauro-Martin I; Ruiz-León AM; Camina-Martín MA; Garicano-Vilar E; Collado-Yurrita L; Mateo-Silleras Bd; Redondo Del Río Mde P · Nutricion hospitalaria · 2017
Meta-analysis13 studies pooledflagMetabolism Boost forscienceChromium
- Effects of caffeine on alertness.
Zwyghuizen-Doorenbos A; Roehrs TA; Lipschutz L; Timms V; Roth T · Psychopharmacology · 1990
Randomized trial24 participantsflagProductivity Boost forscienceCaffeine
- Effects of Different Sources of Low-Dose Caffeine on Mood/Arousal and Cognitive Performance.
Irwin C; McCartney D; Grant G; Delang N; Bartrim K; Cox GR; Desbrow B · Perceptual and motor skills · 2023
Randomized trial22 participantsflagProductivity Boost forscienceCaffeine
- Effects of caffeine, sleep loss, and stress on cognitive performance and mood during U.S. Navy SEAL training. Sea-Air-Land.
Lieberman HR; Tharion WJ; Shukitt-Hale B; Speckman KL; Tulley R · Psychopharmacology · 2003
Randomized trial68 participantsflagProductivity Boost forscienceCaffeine
- A review of caffeine's effects on cognitive, physical and occupational performance.
McLellan TM; Caldwell JA; Lieberman HR · Neuroscience and biobehavioral reviews · 2017
Narrative reviewflagProductivity Boost forscienceCaffeine
- Acute caffeine supplementation as a nutrition-based strategy to mitigate sleep-loss-related cognitive and operational performance impairments in military personnel: a systematic review and meta-analysis.
Wang R; Wang W; Meng L; Hao G; Gu G · Frontiers in nutrition · 2026
Meta-analysis7 studies pooledflagProductivity Boost forscienceCaffeine
- Changes in caffeine intake and long-term weight change in men and women.
Lopez-Garcia E; van Dam RM; Rajpathak S; Willett WC; Manson JE; Hu FB · The American journal of clinical nutrition · 2006
Cohort study58,157 participantsflagWeight Loss forscienceCaffeine
- Does caffeine ingestion before a short-term sprint interval training promote body fat loss?
Ferreira GA; Felippe LC; Bertuzzi R; Bishop DJ; Ramos IS; De-Oliveira FR; Lima-Silva AE · Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2020
Randomized trial20 participantsflagWeight Loss forscienceCaffeine
- Eight Weeks of Sprint Interval Training With Adding Caffeine Ingestion Leads to Greater Improvements in Health-Related Physiological Parameters in Obese Male Adults.
Zhiang J; Song Q · Physiological research · 2026
Randomized trial30 participantsflagWeight Loss forscienceCaffeine
- Caffeine treatment prevented from weight regain after calorie shifting diet induced weight loss.
Davoodi SH; Hajimiresmaiel SJ; Ajami M; Mohseni-Bandpei A; Ayatollahi SA; Dowlatshahi K; Javedan G; Pazoki-Toroudi H · Iranian journal of pharmaceutical research : IJPR · 2014
Non-randomized trial60 participantsflagWeight Loss forscienceCaffeine
- The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials.
Tabrizi R; Saneei P; Lankarani KB; Akbari M; Kolahdooz F; Esmaillzadeh A; Nadi-Ravandi S; Mazoochi M; Asemi Z · Critical reviews in food science and nutrition · 2020
Meta-analysis606 participants13 studies pooledflagWeight Loss forscienceCaffeine
- The Influences of Chromium Supplementation on Metabolic Status in Patients with Type 2 Diabetes Mellitus and Coronary Heart Disease.
Farrokhian A; Mahmoodian M; Bahmani F; Amirani E; Shafabakhsh R; Asemi Z · Biological trace element research · 2021
Randomized trial64 participantsflagWeight Loss forscienceChromium
- Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes.
Martin J; Wang ZQ; Zhang XH; Wachtel D; Volaufova J; Matthews DE; Cefalu WT · Diabetes care · 2006
Randomized trial37 participantsflagWeight Loss forscienceChromium
- Chromium picolinate reduces insulin resistance in polycystic ovary syndrome: Randomized controlled trial.
Ashoush S; Abou-Gamrah A; Bayoumy H; Othman N · The journal of obstetrics and gynaecology research · 2017
Randomized trial100 participantsflagWeight Loss forscienceChromium
- Chromium supplementation and polycystic ovary syndrome: A systematic review and meta-analysis.
Fazelian S; Rouhani MH; Bank SS; Amani R · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2018
Meta-analysis351 participants7 studies pooledflagWeight Loss forscienceChromium
- Chromium picolinate balances the metabolic and clinical markers in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial.
Kooshki F; Moradi F; Karimi A; Niazkar HR; Khoshbaten M; Maleki V; Pourghassem Gargari B · European journal of gastroenterology & hepatology · 2021
Randomized trial46 participantsflagWeight Loss forscienceChromium
- A green tea extract high in catechins reduces body fat and cardiovascular risks in humans.
Nagao T; Hase T; Tokimitsu I · Obesity (Silver Spring, Md.) · 2007
Randomized trial240 participantsflagWeight Loss forscienceGreen Tea
- Green tea beverages enriched with catechins with a galloyl moiety reduce body fat in moderately obese adults: a randomized double-blind placebo-controlled trial.
Kobayashi M; Kawano T; Ukawa Y; Sagesaka YM; Fukuhara I · Food & function · 2016
Randomized trial126 participantsflagWeight Loss forscienceGreen Tea
- Green tea catechin consumption enhances exercise-induced abdominal fat loss in overweight and obese adults.
Maki KC; Reeves MS; Farmer M; Yasunaga K; Matsuo N; Katsuragi Y; Komikado M; Tokimitsu I; Wilder D; Jones F; Blumberg JB; Cartwright Y · The Journal of nutrition · 2009
Randomized trial132 participantsflagWeight Loss forscienceGreen Tea
- Effect of Decaffeinated Green Tea Polyphenols on Body Fat and Precocious Puberty in Obese Girls: A Randomized Controlled Trial.
Xie L; Tang Q; Yao D; Gu Q; Zheng H; Wang X; Yu Z; Shen X · Frontiers in endocrinology · 2022
Randomized trial62 participantsflagWeight Loss forscienceGreen Tea
- Effectiveness of green tea on weight reduction in obese Thais: A randomized, controlled trial.
Auvichayapat P; Prapochanung M; Tunkamnerdthai O; Sripanidkulchai BO; Auvichayapat N; Thinkhamrop B; Kunhasura S; Wongpratoom S; Sinawat S; Hongprapas P · Physiology & behavior · 2008
Randomized trial60 participantsflagWeight Loss forscienceGreen Tea