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Menopause Comfort Support

Zoi Research
4.5
★ ★ ★ ★ ★
(888 ratings)
Theanine 100 mg
Vitamin B6 25 mg
Product Image
Score64
A coherent menopause blend with isoflavones, black cohosh, and L-theanine. Proprietary ingredients and high vitamin B6 reduce confidence in long-term use.
How scoring works
Quantity:56 Capsule(s) • (28 servings)
Goals:
Stress Relief

Score 64

A coherent menopause blend with isoflavones, black cohosh, and L-theanine. Proprietary ingredients and high vitamin B6 reduce confidence in long-term use.
How scoring works
$10.68($0.38 per serving)
iHerb
$ 10.68
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Analysis

Red clover, soy isoflavones, black cohosh, and L-theanine create a coherent menopause-oriented blend. The named ingredients and their amounts cover both vasomotor and calming-related support without making the formula excessively large.

The 82 mg calming blend and 23 mg absorption blend do not disclose individual ingredients or doses. Vitamin B6 reaches 25 mg as pyridoxine hydrochloride, which is aggressive for prolonged daily stacking.

The product may fit adults seeking a compact menopause-support formula who can review hormone-related cautions. People with hormone-sensitive conditions or complex medication regimens need a more transparent option.

Who is it for
  • Adults seeking nonprescription menopause support
  • Users comfortable with soy and red clover isoflavones
Best for
  • Menopause-related comfort and calm support
  • Short, carefully reviewed use

Pros

  • Includes named soy isoflavones
  • Meaningful L-theanine amount
  • Includes red clover and black cohosh
  • Two-capsule serving

Cons

  • Two proprietary blends hide component doses
  • Vitamin B6 amount is high
  • Uses pyridoxine hydrochloride
  • Complex botanical profile limits stacking

Warnings

  • Red clover and soy isoflavones warrant extra care with hormone-sensitive conditions or hormone-modulating treatment.
  • Vitamin B6 at 25 mg may contribute to nerve symptoms during prolonged use, especially when stacked.
  • Black cohosh may not suit people with liver concerns, and unexplained dark urine or jaundice warrants prompt medical attention.

Nutrient quality

68 High impact

Isoflavones, black cohosh, and L-theanine provide relevant menopause and calming support. Unstandardized botanicals, hidden blends, and a relatively high vitamin B6 amount reduce balance and confidence.

Ingredient transparency

57 Moderate impact

Named actives have amounts and the serving supply is clear. Two proprietary blends hide component identities or doses, while non-active ingredients and botanical standards are missing.

Customer satisfaction

66 High impact

The average rating is favorable and supported by a substantial review count. No detailed reviews are supplied to assess recurring complaints or menopause-related experiences.

Value for money

68 High impact

Several relevant actives in a simple capsule serving provide reasonable formula value. Hidden blends, incomplete standardization, and a limited supply keep the product from standing out.

Report analysis

Goals

Stress Relief
Stress Relief
Impact
High effect
B- Goal FitB- Strength of SupportC+ CoverageC+ Formula Quality
Folate · 680 mcg DFEVitamin B6 · 25 mgTheanine · 100 mg

L-theanine provides direct calming support, but the wider formula is designed around menopause symptoms rather than general stress relief. B vitamins and several botanicals add metabolic and symptom-focused pathways without a clear adaptogenic core.

Theanine has a useful disclosed amount, while the calming and absorption blends hide their individual contents. Black cohosh warrants caution for people with liver disease or unexplained liver symptoms because rare liver injury has been reported.

Study evidence
Theanine Supportive 16 studies
Productivity Boost
Productivity Boost
Impact
Moderate effect
D Goal FitB Strength of SupportD+ CoverageD Formula Quality
Vitamin B6 · 25 mgTheanine · 100 mg

L-theanine may support calm attention, while vitamin B6 contributes to neurotransmitter synthesis. The wider formula targets menopausal comfort rather than productivity, and proprietary blends obscure several ingredient amounts.

Red clover, soy isoflavones, and black cohosh may indirectly help concentration when symptoms are distracting, but they are not direct cognitive enhancers. Black cohosh warrants caution for people with liver disease or unexplained dark urine, jaundice, or persistent abdominal pain.

Study evidence
Theanine Supportive 5 studies
Vitamin B6 Disputed 6 studies
Brain Health
Brain Health
Impact
Moderate effect
C- Goal FitD+ Strength of SupportC CoverageC- Formula Quality
Folate · 680 mcg DFEVitamin B6 · 25 mg

L-theanine and B vitamins provide some support for calm focus and nervous-system metabolism during menopause. Most of the formula targets hormonal comfort, so cognitive support is secondary rather than central.

Several botanical doses are hidden in proprietary blends, limiting assessment of their contribution. Black cohosh warrants caution with liver disease or unexplained liver symptoms, while soy and red clover may not suit some hormone-sensitive conditions.

Study evidence
Theanine Supportive 17 studies
Mental Focus
Mental Focus
Impact
Moderate effect
C Goal FitC- Strength of SupportD+ CoverageD- Formula Quality
Folate · 680 mcg DFEVitamin B6 · 25 mgTheanine · 100 mg

Theanine may offer mild calm-focus support, with vitamin B6 providing a general neurotransmitter cofactor. Most of the formula instead targets menopausal comfort and relaxation rather than concentration.

Several botanical blends are proprietary, and the theanine amount is at the lower end of common focus use. Black cohosh warrants caution in people with liver concerns, while soy and red-clover isoflavones may be unsuitable for some hormone-sensitive conditions.

Study evidence
Theanine Supportive 19 studies
Vitamin B6 Disputed 6 studies
Mood Support
Mood Support
Impact
Moderate effect
C Goal FitD Strength of SupportC CoverageD+ Formula Quality
Folate · 680 mcg DFEVitamin B6 · 25 mg

L-theanine and B6 may support calm and neurotransmitter metabolism during menopause, while red clover, soy isoflavones, and black cohosh target menopausal symptoms. Mood support is therefore situational rather than broadly applicable.

Theanine is modest and two proprietary blends hide their ingredients. Black cohosh has rare reports of liver injury, so users with liver disease or new jaundice, dark urine, or upper-abdominal pain should avoid or stop it and seek care.

Study evidence
Folate Supportive 84 studies
Theanine Supportive 12 studies
Vitamin B6 Supportive 19 studies
Cognitive Support
Cognitive Support
Impact
Moderate effect
D+ Goal FitC- Strength of SupportD CoverageD+ Formula Quality
Vitamin B6 · 25 mgFolate · 680 mcg DFETheanine · 100 mg

L-theanine may support calm attention, while vitamin B6 and folate provide basic neurotransmitter cofactors. The remaining herbs and isoflavones are directed at menopause comfort rather than broad cognitive performance.

Two proprietary blends hide supporting ingredients and make the full cognitive contribution impossible to judge. Black cohosh warrants caution for people with liver disease or unexplained liver symptoms because rare liver injury has been reported with its use.

Study evidence
Folate Supportive 68 studies
Theanine Supportive 25 studies
Vitamin B6 Supportive 17 studies
Sleep Support
Sleep Support
Impact
Moderate effect
D Goal FitC+ Strength of SupportD- CoverageD- Formula Quality
Theanine · 100 mg

L-theanine may support relaxation, but the wider formula is designed mainly for menopause comfort rather than sleep. Red clover, soy isoflavones, black cohosh, vitamins, and proprietary blends do not create a focused sleep pathway.

The disclosed theanine amount is useful, although hidden blend contents limit assessment of the complete formula. Black cohosh warrants caution in people with liver disease or unexplained liver symptoms, while red clover and soy isoflavones may be unsuitable for some hormone-sensitive conditions.

Study evidence
Theanine Supportive 8 studies

Ingredients

IngredientAmount per serving
Vitamin B6 (Pyridoxine Hydrochloride)
 25 mg
Folate
680 mcg DFE
Red Clover herb extract
165 mg
Soy Germ Extract (Isoflavones)
 100 mg
L-Theanine
100 mg
Black Cohosh Root Extract
90 mg
Proprietary Calming Blend
82 mg
Proprietary Absorption Blend
23 mg
Adults 18–50 Dairy Free
Report overview
Theanine · 100 mg OverallScore88
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

The clearly disclosed 100 mg of L-theanine falls within an effective range for relaxation and focus support. Its active L-isomer is specified, but no branded source or purity testing is provided. The broader botanical formula improves practical value, although black cohosh warrants caution for people with liver disease or unexplained liver symptoms.

View ingredientView products
Vitamin B6 (Pyridoxine Hydrochloride) · 25 mg OverallScore68
D+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value

Pyridoxine hydrochloride is a precursor form, and no riboflavin cofactor is listed to support conversion. The 25 mg dose sits in the preferred range for metabolic and neurological support. Price per serving is only average for pyridoxine hydrochloride.

View ingredientView products
Loading alternative details
89 Performance

P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength

Swanson
<p>Active pyridoxal phosphate provides a ready-to-use vitamin B6 form with clear dosing, improving on the original unstandardized blend. The high-potency amount still warrants caution with prolonged use, and it offers no menopause botanical or theanine support.</p>
84 Performance

Suntheanine L-Theanine 125 mg

Natural Factors Stress-Relax
<p>Branded Suntheanine provides stronger ingredient identity and clear calming dosage than the hidden blend. The focused formula may support stress and sleep but does not replace red clover, soy isoflavones, or black cohosh.</p>
85 Performance

L-Theanine 150 mg

Solgar
<p>A useful Suntheanine amount combines strong ingredient identity with clear calm-focus dosing. The streamlined capsule improves transparency, though it does not target menopause with isoflavones or black cohosh.</p>
85 Budget

Double Strength L-Theanine 200 mg

NOW
<p>A clearly disclosed L-theanine amount offers more focused calming support at a lower serving cost than the hidden menopause blend. Generic sourcing gives less purity assurance, and the formula does not replace red clover, soy isoflavones, or black cohosh.</p>
84 Budget

L-Theanine 200 mg

Advance Physician Formulas
<p>A practical L-theanine amount improves transparency and lowers recurring cost for calm focus and stress support. No branded source is stated, and the single active does not address the original menopause-focused botanicals.</p>
85 Budget

L-Theanine 200 mg

California Gold Nutrition
<p>Clearly measured L-theanine provides focused stress and attention support at a lower serving cost. Source quality is not characterized, and the capsule omits the original isoflavones and black cohosh.</p>
87 Value

L-Theanine 100 mg

California Gold Nutrition
<p>AlphaWave L-theanine provides a well-characterized amount with clear purpose and favorable serving value. It supports calm attention but does not replace the original menopause-focused botanicals.</p>
83 Value

Chewable L-Theanine 100 mg

NOW
<p>A useful chewable L-theanine amount offers focused stress support and strong practical value. Generic sourcing and modest inositol and taurine limit depth, while menopause-specific ingredients are absent.</p>
82 Value

Theanine 100 mg

Jarrow Formulas
<p>A simple, clearly disclosed L-theanine amount provides moderate daily calming support at a lower serving cost. No branded source or purity marker is supplied, and the formula does not address menopause-specific botanical goals.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial.
    White DJ; de Klerk S; Woods W; Gondalia S; Noonan C; Scholey AB · Nutrients · 2016
    Randomized trial34 participantsStress Relief forTheanine
  2. Effect of Combined Ingestion of L-Theanine and L-Arginine for Short-Term Psychological Stress in Young Adults: A Randomized Placebo-Controlled Study.
    Furushima D; Sugiyama I; Nomura Y; Unno K; Yamada H · Journal of nutritional science and vitaminology · 2023
    Randomized trial120 participantsStress Relief forTheanine
  3. l-theanine adjunct to sertraline for major depressive disorder: A randomized, double-blind, placebo-controlled clinical trial.
    Shamabadi A; Kafi F; Arab Bafrani M; Asadigandomani H; A Basti F; Akhondzadeh S · Journal of affective disorders · 2023
    Randomized trial60 participantsMood Support forTheanine
  4. Cognitive and affective effects of L-Theanine: a systematic review and meta-analysis of 31 randomized trials.
    Gerolymos C; Saddier E; Boyer L; Fond G · Molecular psychiatry · 2026
    Meta-analysis1,168 participants31 studies pooledMood Support Productivity Boost forTheanine
  5. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
    Hidese S; Ogawa S; Ota M; Ishida I; Yasukawa Z; Ozeki M; Kunugi H · Nutrients · 2020
    Randomized trial30 participantsBrain Health Cognitive Support Sleep Support forTheanine
  6. A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWave® L-Theanine on Stress in a Healthy Adult Population.
    Evans M; McDonald AC; Xiong L; Crowley DC; Guthrie N · Neurology and therapy · 2021
    Randomized trialBrain Health Stress Relief forTheanine
  7. Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Payne ER; Aceves-Martins M; Dubost J; Greyling A; de Roos B · Nutrition reviews · 2025
    Meta-analysis50 studies pooledBrain Health Cognitive Support Mental Focus forTheanine
  8. Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task.
    Foxe JJ; Morie KP; Laud PJ; Rowson MJ; de Bruin EA; Kelly SP · Neuropharmacology · 2012
    Randomized trial27 participantsBrain Health Cognitive Support forTheanine
  9. Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study.
    Baba Y; Inagaki S; Nakagawa S; Kaneko T; Kobayashi M; Takihara T · Journal of medicinal food · 2021
    Randomized trialBrain Health Mental Focus Productivity Boost forTheanine
  10. Effects of 6-Month Folic Acid Supplementation on Cognitive Function and Blood Biomarkers in Mild Cognitive Impairment: A Randomized Controlled Trial in China.
    Ma F; Wu T; Zhao J; Han F; Marseglia A; Liu H; Huang G · The journals of gerontology. Series A, Biological sciences and medical sciences · 2017
    Randomized trial180 participantsCognitive Support forFolate
  11. Serum folate and B12 levels in association with cognitive impairment among seniors: results from the VELESTINO study in Greece and meta-analysis.
    Michelakos T; Kousoulis AA; Katsiardanis K; Dessypris N; Anastasiou A; Katsiardani KP; Kanavidis P; Stefanadis C; Papadopoulos FC; Petridou ET · Journal of aging and health · 2013
    Meta-analysis8,122 participants9 studies pooledCognitive Support forFolate
  12. B vitamins and prevention of cognitive decline and incident dementia: a systematic review and meta-analysis.
    Wang Z; Zhu W; Xing Y; Jia J; Tang Y · Nutrition reviews · 2022
    Meta-analysis46,175 participants95 studies pooledCognitive Support forFolate
  13. Homocysteine and folate as risk factors for dementia and Alzheimer disease.
    Ravaglia G; Forti P; Maioli F; Martelli M; Servadei L; Brunetti N; Porcellini E; Licastro F · The American journal of clinical nutrition · 2005
    Cohort study816 participantsCognitive Support forFolate
  14. Folate mediates cognitive impairment of aged people with periodontitis.
    Liu F; Liu Y; Feng Y; Zhao J; Wang M; Ye M; Zhang Y; Gan X; Pan Q; Shen J · Nutritional neuroscience · 2025
    Cross-sectional study1,966 participantsCognitive Support forFolate
  15. Dose-response effect of L-theanine on psychomotor speed, sustained attention, and inhibitory control: a double-blind, placebo-controlled, crossover study.
    Dassanayake TL; Wijesundara D; Kahathuduwa CN; Weerasinghe VS · Nutritional neuroscience · 2023
    Randomized trial32 participantsCognitive Support forTheanine
  16. Acute effects of theanine, caffeine and theanine-caffeine combination on attention.
    Kahathuduwa CN; Dassanayake TL; Amarakoon AMT; Weerasinghe VS · Nutritional neuroscience · 2018
    Clinical trial20 participantsCognitive Support Mental Focus forTheanine
  17. Safety and Efficacy of High-Dose Vitamin B6 as an Adjunctive Treatment for Antipsychotic-Induced Hyperprolactinemia in Male Patients With Treatment-Resistant Schizophrenia.
    Zhuo C; Xu Y; Wang H; Fang T; Chen J; Zhou C; Li Q; Liu J; Xu S; Yao C; Yang W; Yang A; Li B; Chen Y; Tian H; Lin C · Frontiers in psychiatry · 2021
    Randomized trial200 participantsCognitive Support forVitamin B6
  18. Associations between dietary B vitamin intakes and cognitive function among elderly individuals: An observational study.
    Chen Q; Huang J; Shi X; Peng Y; Chen A; Huang L; Zhang Y; Chen X · Nutrition (Burbank, Los Angeles County, Calif.) · 2025
    Cross-sectional study2,716 participantsCognitive Support forVitamin B6
  19. Lower Plasma Vitamin B-6 is Associated with 2-Year Cognitive Decline in the Boston Puerto Rican Health Study.
    Palacios N; Scott T; Sahasrabudhe N; Gao X; Tucker KL · The Journal of nutrition · 2020
    Cohort study949 participantsCognitive Support forVitamin B6
  20. Lower water-soluble vitamins and higher homocysteine are associated with neurodegenerative diseases.
    Zhang C; Hu Y; Cao X; Deng Y; Wang Y; Guan M; Wu X; Jiang H · Scientific reports · 2025
    Cohort study926 participantsCognitive Support forVitamin B6
  21. Associations of one-carbon metabolism, related B-vitamins and ApoE genotype with cognitive function in older adults: identification of a novel gene-nutrient interaction.
    Gordon S; Hoey L; McNulty H; Keenan J; Pangilinan F; Brody LC; Ward M; Strain JJ; McAnena L; McCann A; Molloy AM; Cunningham C; McCarroll K; Hughes CF · BMC medicine · 2025
    Observational study4,553 participantsCognitive Support forVitamin B6
  22. Safety and Efficacy of AlphaWave® L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Moulin M; Crowley DC; Xiong L; Guthrie N; Lewis ED · Neurology and therapy · 2024
    Randomized trial30 participantsMental Focus Productivity Boost Stress Relief forTheanine
  23. Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study.
    Karunaratne UW; Dassanayake TL · Nutritional neuroscience · 2025
    Randomized trial24 participantsMental Focus forTheanine
  24. Vitamin B-6 supplementation in elderly men: effects on mood, memory, performance and mental effort.
    Deijen JB; van der Beek EJ; Orlebeke JF; van den Berg H · Psychopharmacology · 1995
    Randomized trial76 participantsMental Focus forVitamin B6
  25. The effect of vitamin B6 on cognition.
    Malouf R; Grimley Evans J · The Cochrane database of systematic reviews · 2004
    Systematic review109 participants2 studies pooledMental Focus forVitamin B6
  26. Antiemetic use during pregnancy and child neurodevelopment: population-based birth cohort study.
    Cho Y; Choi EY; Han JY; Kim H; Choe YJ; Shin JY · BMC medicine · 2025
    Cohort study630,904 participantsMental Focus forVitamin B6
  27. A nutritional blend of taurine, vitamins B6, B9, and B12 improves motivated behaviors in healthy adults-a double-blinded randomized clinical trial.
    Anlacan VM; Jamora RDG; Krattinger LF; De Longis E; Hartweg M; Steinmann M; Trovò L · Frontiers in nutrition · 2026
    Randomized trial44 participantsMental Focus Productivity Boost forVitamin B6
  28. B-Vitamin Therapy for Kidney Transplant Recipients Lowers Homocysteine and Improves Selective Cognitive Outcomes in the Randomized FAVORIT Ancillary Cognitive Trial
    Tammy M Scott, Graham Rogers, Daniel E Weiner, Kathryn Livingston, Jacob Selhub, Paul F Jacques, Irwin H Rosenberg, Aron M Troen · The Journal of Prevention of Alzheimer's Disease · 2017
    Randomized trial584 participantsMental Focus forVitamin B6
  29. The efficacy and safety of nutrient supplements in the treatment of mental disorders: a meta-review of meta-analyses of randomized controlled trials.
    Firth J; Teasdale SB; Allott K; Siskind D; Marx W; Cotter J; Veronese N; Schuch F; Smith L; Solmi M; Carvalho AF; Vancampfort D; Berk M; Stubbs B; Sarris J · World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025
    Systematic review10,951 participants33 studies pooledMood Support forFolate
  30. Continuous supplementation of folic acid in pregnancy and the risk of perinatal depression-A meta-analysis.
    Jin X; Cheng Z; Yu X; Tao Q; Huang R; Wang S · Journal of affective disorders · 2022
    Meta-analysis26,275 participants15 studies pooledMood Support forFolate
  31. Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials.
    Borges-Vieira JG; Cardoso CKS · Nutritional neuroscience · 2023
    Systematic review2,256 participants20 studies pooledMood Support forFolate
  32. Folate supplementation as a beneficial add-on treatment in relieving depressive symptoms: A meta-analysis of meta-analyses.
    Gao S; Khalid A; Amini-Salehi E; Radkhah N; Jamilian P; Badpeyma M; Zarezadeh M · Food science & nutrition · 2024
    Meta-analysis11 studies pooledMood Support forFolate
  33. Oral 5'-methyltetrahydrofolic acid in senile organic mental disorders with depression: results of a double-blind multicenter study.
    Passeri M; Cucinotta D; Abate G; Senin U; Ventura A; Stramba Badiale M; Diana R; La Greca P; Le Grazie C · Aging (Milan, Italy) · 1993
    Randomized trial96 participantsMood Support forFolate
  34. L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study.
    Ritsner MS; Miodownik C; Ratner Y; Shleifer T; Mar M; Pintov L; Lerner V · The Journal of clinical psychiatry · 2011
    Randomized trial60 participantsMood Support Stress Relief forTheanine
  35. The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review.
    Williams JL; Everett JM; D'Cunha NM; Sergi D; Georgousopoulou EN; Keegan RJ; McKune AJ; Mellor DD; Anstice N; Naumovski N · Plant foods for human nutrition (Dordrecht, Netherlands) · 2020
    Systematic review9 studies pooledMood Support forTheanine
  36. Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
    Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK · Journal of anaesthesiology, clinical pharmacology · 2025
    Randomized trial168 participantsMood Support Stress Relief forTheanine
  37. Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activity, trait anxiety and subjective stress.
    Unno K; Tanida N; Ishii N; Yamamoto H; Iguchi K; Hoshino M; Takeda A; Ozawa H; Ohkubo T; Juneja LR; Yamada H · Pharmacology, biochemistry, and behavior · 2014
    Randomized trial20 participantsMood Support forTheanine
  38. High Dose Vitamin B6 Reduces Depression Symptoms.
    Field DT; Cracknell R; Biagi N · Depression and anxiety · 2026
    Randomized trial267 participantsMood Support forVitamin B6
  39. Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
    Khodadad M; Bahadoran P; Kheirabadi GR; Sabzghabaee AM · International journal of preventive medicine · 2022
    Randomized trial81 participantsMood Support forVitamin B6
  40. Associations of Dietary Intake of Vitamin B6 and Plasma Pyridoxal 5'-Phosphate Level With Depression in US Adults: Findings From NHANES 2005-2010.
    Lu J; Mao H; Tan Y; Luo G · Brain and behavior · 2024
    Cross-sectional study24,683 participantsMood Support forVitamin B6
  41. Associations of dietary B vitamins intakes with depression in adults.
    Wu Y; Li S; Wang W; Zhang D · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2023
    Observational study17,732 participantsMood Support forVitamin B6
  42. Impact of vitamin B6 status on psychological distress in a longitudinal study of HIV-1 infection.
    Shor-Posner G; Feaster D; Blaney NT; Rocca H; Mantero-Atienza E; Szapocznik J; Eisdorfer C; Goodkin K; Baum MK · International journal of psychiatry in medicine · 1995
    Cohort study88 participantsMood Support forVitamin B6
  43. Effects of L-theanine on cognition, mood and sleep: evidence from human trials.
    Cotter J; Kilpatrick HE · Frontiers in nutrition · 2026
    Narrative reviewProductivity Boost forTheanine
  44. Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together.
    Rogers PJ; Smith JE; Heatherley SV; Pleydell-Pearce CW · Psychopharmacology · 2008
    Randomized trial48 participantsProductivity Boost forTheanine
  45. Vitamin B6, B9, and B12 Intakes and Cognitive Performance in Elders: National Health and Nutrition Examination Survey, 2011-2014.
    Xu H; Wang S; Gao F; Li C · Neuropsychiatric disease and treatment · 2022
    Cross-sectional study2,421 participantsProductivity Boost forVitamin B6
  46. Effect of megavitamin treatment on mental performance and plasma vitamin B6 concentrations in mentally retarded young adults.
    Coburn SP; Schaltenbrand WE; Mahuren JD; Clausman RJ; Townsend D · The American journal of clinical nutrition · 1983
    Non-randomized trialProductivity Boost forVitamin B6
  47. Identifying Key Predictors of Cognitive Dysfunction in Older People Using Supervised Machine Learning Techniques: Observational Study.
    Rankin D; Black M; Flanagan B; Hughes CF; Moore A; Hoey L; Wallace J; Gill C; Carlin P; Molloy AM; Cunningham C; McNulty H · JMIR medical informatics · 2024
    Cohort studyProductivity Boost forVitamin B6
  48. Inappropriate nutrients intake is associated with lower functional status and inferior quality of life in older adults with depression.
    Guligowska A; Pigłowska M; Fife E; Kostka J; Sołtysik BK; Kroc Ł; Kostka T · Clinical interventions in aging · 2017
    Case-control study49 participantsProductivity Boost forVitamin B6
  49. Comparison Between Efficacy of Oral Melatonin and Oral L-theanine in Improving Sleep in Cancer Patients Suffering From Insomnia: A Randomised Double-blinded Placebo-controlled Study.
    Kurdi MS; As A; Ladhad DA; Mitragotri MV; Baiju A · Indian journal of palliative care · 2024
    Randomized trial120 participantsSleep Support forTheanine
  50. The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis.
    Bulman A; D'Cunha NM; Marx W; Turner M; McKune A; Naumovski N · Sleep medicine reviews · 2025
    Meta-analysis897 participants19 studies pooledSleep Support forTheanine
  51. In Search of a Safe Natural Sleep Aid.
    Rao TP; Ozeki M; Juneja LR · Journal of the American College of Nutrition · 2016
    Narrative reviewSleep Support forTheanine
  52. L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial.
    Sarris J; Byrne GJ; Cribb L; Oliver G; Murphy J; Macdonald P; Nazareth S; Karamacoska D; Galea S; Short A; Ee C; Birling Y; Menon R; Ng CH · Journal of psychiatric research · 2020
    Randomized trial46 participantsSleep Support forTheanine