Product Image

KidsActive Fruit Punch Flavor

Advanced Nutrition by Zahler
4.2
★ ★ ★ ★ ★
(469 ratings)
Deanol 100 mg
Zinc 15 mg
Magnesium 300 mg
Product Image
Score69
Broad child-focused coverage is undermined by weak mineral forms and limited age-specific dosing clarity.
How scoring works
Quantity:192 Gram(s) • (30 servings)
Goals:
Energy
Productivity Boost

Score 69

Broad child-focused coverage is undermined by weak mineral forms and limited age-specific dosing clarity.
How scoring works
$28.57($0.95 per serving)
Pure Formulas
$ 28.57
Walmart
$ 28.57
Vitacost
$ 28.57
Amazon
$ 28.57
iHerb
$ 33.23
Pure Formulas
$ 28.57
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Analysis

The powder combines B vitamins with calcium, magnesium, zinc, dimethylglycine, phosphatidylserine, DMAE, and inositol. That breadth may appeal to families seeking an all-in-one activity and cognition formula.

Magnesium oxide and zinc oxide are less favorable forms, and calcium may compete with magnesium during absorption. DMAE active yield is not stated, while the supplied data gives no clear age-based serving guidance.

The formula is too complex for casual use in children without checking the current label and pediatric suitability. A simpler product may be easier to match to a specific nutritional need.

Who is it for
  • Families considering a broad child-focused powder
  • Children able to use the labeled age-specific serving
  • Caregivers willing to review the full formula
Best for
  • Broad micronutrient coverage
  • Powder delivery
  • Combined phosphatidylserine and DMG

Pros

  • Includes methylcobalamin
  • Provides phosphatidylserine and DMG
  • Broad vitamin and mineral range

Cons

  • Uses magnesium oxide
  • Uses zinc oxide
  • DMAE yield and child guidance are incomplete

Warnings

  • Use only the age-specific serving on the current label and review it with a pediatric clinician
  • The 15 mg zinc amount may cause nausea, especially on an empty stomach
  • DMAE and phosphatidylserine may affect sleep or mood in sensitive children

Nutrient quality

65 High impact

Dimethylglycine and phosphatidylserine provide useful cognitive depth within a broad children's powder. Poorly absorbed magnesium and zinc oxides, modest secondary actives, and age-sensitive mineral amounts weaken the design.

Ingredient transparency

80 High impact

Every active has a separate amount and no proprietary blend hides the formula. The intended age range, full dosing guidance, and flavor-system ingredients are not supplied, which limits safe interpretation.

Customer satisfaction

70 High impact

The mixed average rating has a useful review base. No review excerpts describe taste, tolerance, ease of use, or repeated complaints, so those experiences remain uncertain.

Value for money

59 Moderate impact

Meaningful phosphatidylserine and dimethylglycine provide some premium value. Weak mineral forms, age-sensitive dosing, and a modest supply reduce competitiveness.

Report analysis

Goals

Energy
Energy
Impact
High effect
B- Goal FitC+ Strength of SupportB- CoverageC+ Formula Quality
Vitamin B5 · 9 mgMagnesium · 300 mgRiboflavin · 6 mgThiamin · 6 mgVitamin B12 · 50 mcg

B vitamins, magnesium, dimethylglycine, and phosphatidylserine cover metabolic and cognitive energy pathways. The 300 mg magnesium amount is substantial, while several B vitamins provide useful metabolic cofactors.

Magnesium oxide and zinc oxide weaken absorption, and the 50 mcg methylcobalamin amount falls below the stated higher-energy threshold. The broad child-focused formula has moderate depth but includes several cognitive add-ons with less consistent energy evidence.

Study evidence
Magnesium Supportive 4 studies
Productivity Boost
Productivity Boost
Impact
High effect
C+ Goal FitC Strength of SupportC+ CoverageC+ Formula Quality
Vitamin B12 · 50 mcgVitamin B12 · 50 mcgVitamin B6 · 6 mgZinc · 15 mgMagnesium · 300 mg

Phosphatidylserine, dimethylglycine, DMAE, active B12, and B vitamins give the children’s powder a plausible cognitive-support design. Evidence is strongest for phosphatidylserine, while several other ingredients have limited or inconsistent focus data.

Phosphatidylserine reaches a useful amount and all principal actives are disclosed. Magnesium and zinc use poorly absorbed oxide forms, which reduces broader nutritional quality.

Study evidence
Magnesium Supportive 10 studies
Zinc Supportive 11 studies
Mood Support
Mood Support
Impact
Moderate effect
C Goal FitC Strength of SupportC+ CoverageC Formula Quality
Vitamin B6 · 6 mgVitamin B12 · 50 mcgMagnesium · 300 mg

Phosphatidylserine, magnesium, vitamin B6, methylcobalamin, and inositol provide a modest foundation for stress and brain function. Phosphatidylserine at 125 mg and magnesium at 300 mg are meaningful, while inositol at 50 mg is very low for targeted use.

The formula covers neuronal membranes, mineral cofactors, and B-vitamin support through several mechanisms. The brain nutrients fit together reasonably, though the formula lacks a direct adaptogen or neurotransmitter precursor.

Study evidence
Magnesium Supportive 60 studies
Vitamin B6 Supportive 19 studies
Stress Relief
Stress Relief
Impact
Moderate effect
C+ Goal FitC Strength of SupportC+ CoverageD+ Formula Quality
Magnesium · 300 mgVitamin B12 · 50 mcgVitamin B6 · 6 mg

Phosphatidylserine, magnesium, and B vitamins provide several plausible stress-resilience pathways. Dimethylglycine and DMAE shift part of the formula toward attention rather than calm.

Phosphatidylserine is meaningfully dosed, but magnesium oxide has poor absorption and the inositol amount is small. The 300 mg magnesium oxide amount may cause digestive upset in children, and the complex cognitive-active blend warrants age-appropriate supervision.

Study evidence
Magnesium Supportive 13 studies
Cognitive Support
Mental Energy
Cognitive Support
Impact
Moderate effect
C Goal FitC Strength of SupportC CoverageC Formula Quality
Thiamin · 6 mgVitamin B6 · 6 mgVitamin B12 · 50 mcgMagnesium · 300 mg

Phosphatidylserine provides the clearest cognitive active, while B vitamins and minerals offer foundational support. DMAE and dimethylglycine have weaker or less consistent human evidence for attention outcomes.

Magnesium and zinc amounts are useful, but oxide forms limit absorption and the active DMAE yield is not shown. Because the formula is intended for children, the limited safety detail for DMAE deserves cautious use.

Study evidence
Magnesium Supportive 24 studies
Zinc Supportive 48 studies
General Health
General Health
Impact
Moderate effect
C+ Goal FitC- Strength of SupportC+ CoverageD+ Formula Quality
Vitamin B12 · 50 mcgMagnesium · 300 mgZinc · 15 mg

B vitamins and several minerals provide a nutritional base, but poorly absorbed magnesium and zinc oxides limit mineral quality. The formula also extends into cognition-oriented compounds with less established value for children.

Dimethylglycine, phosphatidylserine, and DMAE make the blend difficult to judge as a routine children’s supplement. DMAE has limited pediatric safety evidence, so its inclusion deserves individualized review before ongoing use.

Study evidence
Magnesium Supportive 114 studies
Zinc Supportive 60 studies

Ingredients

IngredientAmount per serving
Thiamine (Thiamine Hydrochloride)
 6 mg
Riboflavin
6 mg
Niacin
18 mg
Vitamin B6 (Pyridoxine Hydrochloride)
 6 mg
Vitamin B12 (Methylcobalamin)
 50 mcg
Pantothenic Acid (Calcium D-Pantothenate)
 9 mg
Calcium (Calcium Carbonate, Calcium Citrate)
 200 mg
Magnesium (Magnesium Oxide)
 300 mg
Zinc (Zinc Oxide)
 15 mg
Dimethylglycine
500 mg
Phosphatidylserine
125 mg
Stevia leaf extract
110 mg
Dimethylaminoethanol Bitartrate
100 mg
Inositol
50 mg
Gluten Free Kosher Dairy Free Children 4+ Vegetarian
Report overview
Deanol · 100 mg OverallScore72
B- Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyC Value

The label clearly identifies DMAE bitartrate, but it does not state how much active Deanol the salt supplies. The calculated active amount is appropriate for a children's formula and comes in a practical single-scoop serving. Safety information specific to Deanol is not provided, while the broad multi-ingredient formula makes a simple ingredient-level value comparison less meaningful.

View ingredientView products
Zinc (Zinc Oxide) · 15 mg OverallScore53
F Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value

The 15 mg amount is suitable for maintenance, but zinc oxide provides weak absorption and may cause more stomach discomfort. A powder serving dissolves readily but does not correct the low-quality mineral form, and no copper is listed. High serving cost leads to poor zinc value.

View ingredientView products
Magnesium (Magnesium Oxide) · 300 mg OverallScore50
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
+2

The magnesium source is magnesium oxide, which is poorly absorbed for systemic use. The label clearly identifies a useful elemental amount and includes vitamin B6, but calcium is also present. The relatively high serving cost and low-quality magnesium form limit its fit for a magnesium-focused collection.

View ingredientView products
Loading alternative details
80 Performance

ZMA

PrimaForce
Magnesium aspartate, zinc aspartate and monomethionine, and vitamin B6 create a compact mineral formula with clearer recovery-oriented intent. The magnesium and zinc amounts are high for prolonged use, and the product lacks the original phosphatidylserine and deanol.
78 Performance

ZMX2

ALLMAX
Bisglycinate and citrate magnesium plus active pyridoxal-5-phosphate improve form quality compared with the original magnesium oxide. Duplicate dose entries create uncertainty, and no phosphatidylserine or deanol is supplied.
80 Performance

Calcium Magnesium plus Zinc

Solgar
Citrate and gluconate forms improve the mineral profile while retaining meaningful magnesium and zinc amounts. Carbonate and magnesium oxide keep absorption mixed, and the formula is aimed at general mineral support rather than cognition.
81 Budget

Zinc Magnesium & Vitamin B6

Sierra Fit
A much lower serving cost still provides 300 mg magnesium, 20 mg zinc, and vitamin B6. Magnesium oxide lowers absorption quality, and the formula omits phosphatidylserine, dimethylglycine, and deanol.
80 Budget

Magnesium & Calcium

NOW
The formula costs less per serving and combines magnesium with calcium, zinc, and vitamin D3. The listed magnesium amount is unusually high and may cause digestive effects, while cognitive ingredients from the original are absent.
78 Budget

Chelated Calcium Magnesium Zinc

American Health
A very low serving cost provides substantial magnesium, calcium, and zinc for broad mineral support. Carbonate and oxide forms reduce absorption quality, and the product does not match the original attention-focused ingredients.
79 Value

Calcium Magnesium & Zinc

Sundown
Meaningful mineral amounts and a low serving cost provide broad calcium, magnesium, and zinc value. Basic carbonate and oxide forms limit quality, while cognitive ingredients from the original are absent.
78 Value

Calcium Magnesium Zinc + Vitamin D3

Best Naturals
A large supply combines vitamin D3 with substantial calcium, magnesium, and zinc at a low recurring cost. Absorption quality is uneven because carbonate and oxide forms remain part of the blend.
80 Value

Calcium Magnesium Zinc + D3

21st Century
Economical servings cover calcium, magnesium, zinc, and vitamin D3 in a simple formula. The nutrients rely on basic carbonate and oxide forms, and the product does not replace the original focus-oriented compounds.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Oral zinc supplementation for the treatment of acute diarrhea in children: a systematic review and meta-analysis.
    Lamberti LM; Walker CL; Chan KY; Jian WY; Black RE · Nutrients · 2014
    Meta-analysis18,822 participants104 studies pooledDigestive Health forZinc
  2. Zinc supplementation for preventing mortality, morbidity, and growth failure in children aged 6 months to 12 years.
    Imdad A; Rogner J; Sherwani RN; Sidhu J; Regan A; Haykal MR; Tsistinas O; Smith A; Chan XHS; Mayo-Wilson E; Bhutta ZA · The Cochrane database of systematic reviews · 2023
    Meta-analysis219,584 participants96 studies pooledDigestive Health forZinc
  3. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  4. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  5. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  6. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  7. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  8. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  9. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  10. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  11. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  12. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  13. Increased incidence of fractures in middle-aged and elderly men with low intakes of phosphorus and zinc.
    Elmståhl S; Gullberg B; Janzon L; Johnell O; Elmståhl B · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 1999
    Cohort study6,576 participantsBone Health forZinc
  14. Zinc Supplementation Increases Procollagen Type 1 Amino-Terminal Propeptide in Premenarcheal Girls: A Randomized Controlled Trial.
    Berger PK; Pollock NK; Laing EM; Chertin V; Bernard PJ; Grider A; Shapses SA; Ding KH; Isales CM; Lewis RD · The Journal of nutrition · 2016
    Randomized trial147 participantsBone Health forZinc
  15. Randomized controlled trial of prenatal zinc supplementation and fetal bone growth.
    Merialdi M; Caulfield LE; Zavaleta N; Figueroa A; Costigan KA; Dominici F; Dipietro JA · The American journal of clinical nutrition · 2004
    Randomized trial242 participantsBone Health forZinc
  16. The effects of zinc supplementation on serum zinc, alkaline phosphatase activity and fracture healing of bones.
    Sadighi A; Roshan MM; Moradi A; Ostadrahimi A · Saudi medical journal · 2009
    Randomized trial60 participantsBone Health forZinc
  17. Is Zinc an Important Trace Element on Bone-Related Diseases and Complications? A Meta-analysis and Systematic Review from Serum Level, Dietary Intake, and Supplementation Aspects.
    Ceylan MN; Akdas S; Yazihan N · Biological trace element research · 2021
    Meta-analysis40 studies pooledBone Health forZinc
  18. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  19. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  20. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  21. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  22. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  23. Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus.
    Doyle LW; Crowther CA; Middleton P; Marret S; Rouse D · The Cochrane database of systematic reviews · 2009
    Meta-analysis6,145 participants5 studies pooledCognitive Support forMagnesium
  24. Effects of magnesium valproate adjuvant therapy on patients with dementia: A systematic review and meta-analysis.
    Zhang C; Sun L; Sun H · Medicine · 2022
    Meta-analysis1,899 participants22 studies pooledCognitive Support forMagnesium
  25. Effects of magnesium supplementation on serum brain-derived neurotrophic factor levels and cognitive function in patients undergoing fluoxetine therapy for depression.
    Noor NJ; Syamsuddin S; Liaury K; Tawali S; Idris I; Azis I; Lisal ST · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan · 2026
    Randomized trial40 participantsCognitive Support forMagnesium
  26. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsCognitive Support Energy forMagnesium
  27. Could intraoperative magnesium sulphate protect against postoperative cognitive dysfunction?
    Hassan WF; Tawfik MH; Nabil TM; Abd Elkareem RM · Minerva anestesiologica · 2021
    Randomized trial80 participantsCognitive Support forMagnesium
  28. Efficacy of Zinc Supplement in Minimal hepatic Encephalopathy: A prospective, Randomized Controlled Study (Zinc-MHE Trial).
    Janyajirawong R; Vilaichone RK; Sethasine S · Asian Pacific journal of cancer prevention : APJCP · 2021
    Randomized trial69 participantsCognitive Support forZinc
  29. Effects of zinc supplementation on parent and teacher behaviour rating scores in low socioeconomic level Turkish primary school children.
    Uçkardeş Y; Ozmert EN; Unal F; Yurdakök K · Acta paediatrica (Oslo, Norway : 1992) · 2009
    Randomized trial226 participantsCognitive Support forZinc
  30. L-shaped association between dietary zinc intake and cognitive decline in Chinese older people.
    Meng Q; Liu M; Zu C; Su X; Wei Y; Gan X; Zhang Y; He P; Zhou C; Ye Z; Liu C; Qin X · Age and ageing · 2024
    Cohort study3,106 participantsCognitive Support forZinc
  31. The efficacy of zinc augmentation in children with attention deficit hyperactivity disorder under treatment with methylphenidate: A randomized controlled trial.
    Noorazar SG; Malek A; Aghaei SM; Yasamineh N; Kalejahi P · Asian journal of psychiatry · 2021
    Randomized trial60 participantsCognitive Support forZinc
  32. A preliminary report: effects of zinc and micronutrient repletion on growth and neuropsychological function of urban Chinese children.
    Penland JG; Sandstead HH; Alcock NW; Dayal HH; Chen XC; Li JS; Zhao F; Yang JJ · Journal of the American College of Nutrition · 1997
    Randomized trial372 participantsCognitive Support forZinc
  33. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  34. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  35. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  36. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  37. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  38. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  39. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  40. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  41. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  42. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  43. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  44. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  45. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  46. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  47. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  48. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  49. Hypomagnesemia Is a Risk Factor for Infections after Kidney Transplantation: A Retrospective Cohort Analysis.
    Odler B; Deak AT; Pregartner G; Riedl R; Bozic J; Trummer C; Prenner A; Söllinger L; Krall M; Höflechner L; Hebesberger C; Boxler MS; Berghold A; Schemmer P; Pilz S; Rosenkranz AR · Nutrients · 2021
    Cohort study376 participantsImmunity forMagnesium
  50. Higher Intake of Dietary Magnesium Is Inversely Associated With COVID-19 Severity and Symptoms in Hospitalized Patients: A Cross-Sectional Study.
    Nouri-Majd S; Ebrahimzadeh A; Mousavi SM; Zargarzadeh N; Eslami M; Santos HO; Taghizadeh M; Milajerdi A · Frontiers in nutrition · 2022
    Cross-sectional study250 participantsImmunity forMagnesium
  51. Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D.
    Chaigne-Delalande B; Li FY; O'Connor GM; Lukacs MJ; Jiang P; Zheng L; Shatzer A; Biancalana M; Pittaluga S; Matthews HF; Jancel TJ; Bleesing JJ; Marsh RA; Kuijpers TW; Nichols KE; Lucas CL; Nagpal S; Mehmet H; Su HC; Cohen JI; Uzel G; Lenardo MJ · Science (New York, N.Y.) · 2013
    Single-arm trialImmunity forMagnesium
  52. Effect of magnesium on granulocyte function and on the exercise induced inflammatory response.
    Mooren FC; Golf SW; Völker K · Magnesium research · 2003
    Randomized trialImmunity forMagnesium
  53. Maternal and neonatal outcomes following magnesium sulfate in the setting of chorioamnionitis: a meta-analysis.
    Pergialiotis V; Sapantzoglou I; Rodolaki K; Varthaliti A; Theodora M; Antsaklis P; Thomakos N; Stavros S; Daskalakis G; Papapanagiotou A · Archives of gynecology and obstetrics · 2024
    Meta-analysis6,559 participants8 studies pooledImmunity forMagnesium
  54. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  55. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  56. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  57. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  58. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  59. Protective role of antioxidant supplementation for depression and anxiety: A meta-analysis of randomized clinical trials.
    Wang H; Jin M; Xie M; Yang Y; Xue F; Li W; Zhang M; Li Z; Li X; Jia N; Liu Y; Cui X; Hu G; Dong L; Wang G; Yu Q · Journal of affective disorders · 2023
    Meta-analysis4,049 participants52 studies pooledMood Support forMagnesium
  60. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsMood Support Stress Relief forMagnesium
  61. Magnesium supplementation as an adjunct to fluoxetine therapy for depression.
    Walyddaini AS; Lisal ST; Ilhamuddin; Zainuddin AA; Tanra AJ; Widianingsih Y; Syamsuddin S · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan · 2026
    Randomized trial40 participantsMood Support forMagnesium
  62. The effects of magnesium supplementation on serum level of brain derived neurotrophic factor (BDNF) and depression status in patients with depression.
    Afsharfar M; Shahraki M; Shakiba M; Asbaghi O; Dashipour A · Clinical nutrition ESPEN · 2021
    Randomized trial46 participantsMood Support forMagnesium
  63. Dietary magnesium intake and risk of depression.
    Sun C; Wang R; Li Z; Zhang D · Journal of affective disorders · 2019
    Cross-sectional study17,730 participantsMood Support forMagnesium
  64. High Dose Vitamin B6 Reduces Depression Symptoms.
    Field DT; Cracknell R; Biagi N · Depression and anxiety · 2026
    Randomized trial267 participantsMood Support forVitamin B6
  65. Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
    Khodadad M; Bahadoran P; Kheirabadi GR; Sabzghabaee AM · International journal of preventive medicine · 2022
    Randomized trial81 participantsMood Support forVitamin B6
  66. Associations of Dietary Intake of Vitamin B6 and Plasma Pyridoxal 5'-Phosphate Level With Depression in US Adults: Findings From NHANES 2005-2010.
    Lu J; Mao H; Tan Y; Luo G · Brain and behavior · 2024
    Cross-sectional study24,683 participantsMood Support forVitamin B6
  67. Associations of dietary B vitamins intakes with depression in adults.
    Wu Y; Li S; Wang W; Zhang D · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2023
    Observational study17,732 participantsMood Support forVitamin B6
  68. Impact of vitamin B6 status on psychological distress in a longitudinal study of HIV-1 infection.
    Shor-Posner G; Feaster D; Blaney NT; Rocca H; Mantero-Atienza E; Szapocznik J; Eisdorfer C; Goodkin K; Baum MK · International journal of psychiatry in medicine · 1995
    Cohort study88 participantsMood Support forVitamin B6
  69. Cross-sectional and longitudinal associations of magnesium intake and cognition in the Healthy Aging Longitudinal Study in Taiwan.
    Tao MH; Chuang SC; Wu IC; Chan HT; Cheng CW; Chen HL; Lee MM; Chang HY; Hsiung CA; Hsu CC · European journal of nutrition · 2024
    Cohort study5,663 participantsProductivity Boost forMagnesium
  70. Low levels of serum magnesium are associated with poststroke cognitive impairment in ischemic stroke patients.
    Tu X; Qiu H; Lin S; He W; Huang G; Zhang X; Wu Y; He J · Neuropsychiatric disease and treatment · 2022
    Cohort study327 participantsProductivity Boost forMagnesium
  71. The effects of magnesium L-threonate (Magtein®) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial.
    Lopresti AL; Smith SJ · Frontiers in nutrition · 2026
    Randomized trial100 participantsProductivity Boost forMagnesium
  72. Hypomagnesemia and Acute Cognitive Decline in Older Adults: An Evaluation of Clinical Practice and Cognitive Outcomes at a National Health Service (NHS) Trust in England.
    Lai XN; Sadhwani V; Ng WM; Gani A · Cureus · 2025
    Cohort study667 participantsProductivity Boost forMagnesium
  73. Magnesium Depletion Score as a Novel Predictor of Cognitive Impairment: A Population-Based Cross-Sectional Study From NHANES.
    Chen M; Xue R; Zhang M; Zhang J; Zheng J; Ye D; Sun J · Journal of the American Medical Directors Association · 2025
    Cross-sectional study2,768 participantsProductivity Boost forMagnesium
  74. Zinc supplementation improved cognitive performance and taste acuity in Indian adolescent girls.
    Tupe RP; Chiplonkar SA · Journal of the American College of Nutrition · 2010
    Randomized trial180 participantsProductivity Boost forZinc
  75. Effects of Physical Activity and Micronutrients on Cognitive Performance in Children Aged 6 to 11 Years: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Meli AM; Ali A; Mhd Jalil AM; Mohd Yusof H; Tan MMC · Medicina (Kaunas, Lithuania) · 2022
    Meta-analysisProductivity Boost forZinc
  76. Linkages of biomarkers of zinc with cognitive performance and taste acuity in adolescent girls.
    Chiplonkar SA; Kawade R · International journal of food sciences and nutrition · 2015
    Cross-sectional study403 participantsProductivity Boost forZinc
  77. Associations Between Serum Selenium, Zinc, and Copper Levels and Cognitive Function in the Elderly.
    Charernwat P; Chansirikarnjana S; Panpunuan P; Sritara P; Sirivarasai J · Nutrients · 2025
    Cross-sectional study854 participantsProductivity Boost forZinc
  78. Comparative analysis of methyl-donor nutrient intakes and RCPM cognitive performance among school-aged children.
    Apprey C; Asamoah-Boakye O; Annaful VT; Annan RA · Clinical nutrition ESPEN · 2022
    Cross-sectional study2,073 participantsProductivity Boost forZinc
  79. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  80. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  81. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  82. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium