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Melatonin 3 mg SR

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4.6
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(485 ratings)
Melatonin 3 mg
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Score80

A moderate sustained-release tablet suits overnight support, with morning carryover as the main trade-off.

How scoring works
Quantity:60 Tablet(s) • (60 servings)
Goals:
Sleep Support
Stress Relief

Score 80

A moderate sustained-release tablet suits overnight support, with morning carryover as the main trade-off.

How scoring works
$8.89($0.14 per serving)
Vitacost
$ 8.89
iHerb
$ 8.89
Amazon
$ 13.31
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Analysis

The tablet provides 3 mg sustained-release melatonin. Its release profile is more relevant to staying asleep than a standard immediate-release tablet.

Riboflavin and 4.1 mg B6 add little sleep-specific value. The moderate amount is reasonable, though sustained release may feel stronger into the morning.

Sixty servings and one tablet support practical nightly use. It best fits people whose main problem includes overnight waking rather than only sleep onset.

Who is it for
  • Adults who need overnight sleep maintenance
  • Users comfortable with 3 mg melatonin
  • People wanting one sustained-release tablet
Best for
  • Staying asleep
  • Sleep timing with overnight coverage
  • Established nighttime routines

Pros

  • Sustained-release delivery
  • Moderate 3 mg amount
  • One tablet
  • Sixty servings

Cons

  • B vitamins add little
  • May carry into the morning
  • Not ideal for precise dose adjustment
  • Less focused on very rapid onset

Warnings

  • Sustained release may cause morning drowsiness in sensitive users
  • Do not split the tablet unless the label permits it because release behavior may change
  • Avoid combining with alcohol or sedative medicines

Nutrient quality

91 Highest impact

Sustained release supports overnight delivery. The conservative melatonin amount fits cautious routine use.

Ingredient transparency

82 Highest impact

All listed active ingredients have individual amounts and no proprietary blend hides them. Daily directions and the complete inactive-ingredient list are not supplied.

Customer satisfaction

62 Moderate impact

The supplied average is favorable and the aggregate pool is limited. No specific feedback is provided to assess recurring complaints or whether experience matches the intended use.

Value for money

79 High impact

Serving cost is moderate for the disclosed formula. Supporting additions provide mixed extra value.

Report analysis

Goals

Sleep Support
Sleep Support
Impact
Highest effect
A+ Goal FitA+ Strength of SupportB- CoverageA- Formula Quality
Melatonin · 3 mg

Melatonin directly supports sleep timing and may help with difficulty falling asleep. The 3 mg amount is reasonably aligned with common use and is clearly disclosed in a tablet.

Sensitive users may still experience morning drowsiness, especially when first assessing the serving. Sustained release may help overnight maintenance, while the added B vitamins contribute little direct sleep support.

Study evidence
Melatonin Supportive 181 studies
Stress Relief
Stress Relief
Impact
High effect
C Goal FitA- Strength of SupportC- CoverageC+ Formula Quality
Vitamin B6 · 4.1 mg

Sustained-release melatonin at 3 mg may support sleep continuity when stress disrupts overnight rest. Riboflavin and vitamin B6 add only modest nutritional support for the selected goal.

The formula remains mainly a sleep product rather than a direct daytime stress aid. Melatonin may cause next-day drowsiness, vivid dreams, or headache in sensitive users.

Study evidence
Melatonin Supportive 21 studies
Vitamin B6 Supportive 10 studies

Ingredients

IngredientAmount per serving
Riboflavin (Vitamin B2)
 2.1 mg
Vitamin B6 (Pyridoxine Hydrochloride)
 4.1 mg
Melatonin
3 mg
Adults 18–50 Vegetarian
Report overview
Melatonin · 3 mg OverallScore73
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA- Value

The physiological melatonin amount and sustained-release design support both sleep onset and overnight maintenance. One tablet supplies the complete serving, although a hard tablet may start more slowly than liquid or fast-dissolve forms. The price is near the collection median, but independent purity verification is not provided.

View ingredientView products
Loading alternative details
88 Performance

Melatonin 1.0 mg Orange Flavor

Source Naturals Sleep Science
<p>The dissolving tablet offers a clearly disclosed 1 mg amount for prompt sleep-onset use, providing a lower dose than the original's 3 mg. Its immediate-release design favors sleep onset and does not replace the original’s overnight-release feature.</p>
87 Performance

Melatonin Lozenges 3 mg

Life Extension
<p>The lozenge offers a clearly disclosed 3 mg amount for prompt sleep-onset use, providing the same 3 mg dose as the original. Its immediate-release design favors sleep onset and does not replace the original’s overnight-release feature.</p>
86 Performance

Melatonin 3 mg Fast Dissolve Strawberry Natural Flavor

Natrol
<p>The fast-dissolve tablet offers a clearly disclosed 3 mg amount for prompt sleep-onset use, providing the same 3 mg dose as the original. Its immediate-release design favors sleep onset and does not replace the original’s overnight-release feature.</p>
87 Budget

Melatonin 1 mg

Nature's Bounty
<p>The 1 mg immediate-release tablet provides a lower dose than the original's 3 mg at a lower serving cost. Its immediate-release design favors sleep onset and does not replace the original’s overnight-release feature.</p>
86 Budget

Fast-Dissolve Melatonin 3 mg Artificial Strawberry Flavor

Spring Valley
<p>The 3 mg fast-dissolve tablet provides the same 3 mg dose as the original at a lower serving cost. Its immediate-release design favors sleep onset and does not replace the original’s overnight-release feature.</p>
85 Budget

Melatonin 1 mg

Swanson Premium Brand
<p>The 1 mg immediate-release capsule provides a lower dose than the original's 3 mg at a lower serving cost. Its immediate-release design favors sleep onset and does not replace the original’s overnight-release feature.</p>
85 Value

Quick Dissolve Melatonin 3 mg

Nature's Bounty
<p>The 3 mg quick-dissolve tablet combines a practical sleep-onset dose with a lower serving cost. Its immediate-release design favors sleep onset and does not replace the original’s overnight-release feature.</p>
83 Value

Melatonin 3 mg

NOW
<p>The 3 mg liquid or dissolving format combines a practical sleep-onset dose with a lower serving cost. Its immediate-release design favors sleep onset and does not replace the original’s overnight-release feature. Vitamin B6 is included but adds little direct sleep value.</p>
86 Value

Melatonin Lozenge 2.5 mg

Nature's Way
<p>The 2.5 mg lozenge combines a practical sleep-onset dose with a lower serving cost. Its immediate-release design favors sleep onset and does not replace the original’s overnight-release feature.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  2. Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: A systematic review and meta-analysis.
    Salanitro M; Wrigley T; Ghabra H; de Haan E; Hill CM; Solmi M; Cortese S · Neuroscience and biobehavioral reviews · 2022
    Meta-analysis1,998 participants34 studies pooledSleep Support forMelatonin
  3. Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis.
    Li T; Jiang S; Han M; Yang Z; Lv J; Deng C; Reiter RJ; Yang Y · Frontiers in neuroendocrinology · 2019
    Meta-analysis205 participants7 studies pooledSleep Support forMelatonin
  4. Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial.
    Sletten TL; Magee M; Murray JM; Gordon CJ; Lovato N; Kennaway DJ; Gwini SM; Bartlett DJ; Lockley SW; Lack LC; Grunstein RR; Rajaratnam SMW; Delayed Sleep on Melatonin (DelSoM) Study Group · PLoS medicine · 2019
    Randomized trial116 participantsSleep Support forMelatonin
  5. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  6. Effects of melatonin on postoperative sleep quality: a systematic review, meta-analysis, and trial sequential analysis.
    Tsukinaga A; Mihara T; Takeshima T; Tomita M; Goto T · Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Meta-analysis516 participants8 studies pooledSleep Support forMelatonin
  7. Unintended consequences: college students' melatonin usage, sleep disturbance, and depressive symptoms.
    Peltz JS; Rogge R · Sleep and biological rhythms · 2025
    Cohort study331 participantsSleep Support forMelatonin
  8. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  9. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  10. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin
  11. The impact of oral melatonin on pain and anxiety reduction during venipuncture in pediatric patients: a double-blind randomized clinical trial.
    Rahafard S; Akbari Jokar Z; Hosseini SA; Alaee E · Annals of medicine and surgery (2012) · 2024
    Randomized trial202 participantsStress Relief forMelatonin
  12. Comparison of Effects of Melatonin and Gabapentin on Post Operative Anxiety and Pain in Lumbar Spine Surgery: A Randomized Clinical Trial.
    Javaherforooshzadeh F; Amirpour I; Janatmakan F; Soltanzadeh M · Anesthesiology and pain medicine · 2022
    Randomized trial90 participantsStress Relief forMelatonin
  13. Melatonin for pre- and postoperative anxiety in adults.
    Hansen MV; Halladin NL; Rosenberg J; Gögenur I; Møller AM · The Cochrane database of systematic reviews · 2015
    Meta-analysis774 participants12 studies pooledStress Relief forMelatonin
  14. Effects of melatonin intake on depression and anxiety in postmenopausal women: a systematic review and meta-analysis of randomised controlled trials.
    Demirhan Kayacik A; İlcioglu K · Archives of women's mental health · 2024
    Meta-analysis441 participants5 studies pooledStress Relief forMelatonin
  15. Premedication effect of melatonin on propofol induction dose for anesthesia, anxiety, orientation and sedation after abdominal surgery: a double-blinded randomized trial.
    Norouzi A; Fateh S; Modir H; Kamali A; Akrami L · Medical gas research · 2020
    Randomized trial88 participantsStress Relief forMelatonin
  16. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forVitamin B6
  17. Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
    Khodadad M; Bahadoran P; Kheirabadi GR; Sabzghabaee AM · International journal of preventive medicine · 2022
    Randomized trial81 participantsStress Relief forVitamin B6
  18. RENAL PROTECTIVE EFFECT AND CLINICAL ANALYSIS OF VITAMIN B 6 IN PATIENTS WITH SEPSIS.
    Wang Y; Lu WL; Feng WM; Xu W; Liu LH; He LM · Shock (Augusta, Ga.) · 2024
    Randomized trial128 participantsStress Relief forVitamin B6
  19. Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial.
    Pouteau E; Kabir-Ahmadi M; Noah L; Mazur A; Dye L; Hellhammer J; Pickering G; Dubray C · PloS one · 2019
    Randomized trial264 participantsStress Relief forVitamin B6
  20. Associations between dietary intake of B-vitamins and psychological disorders among Iranian women: a cross-sectional study.
    Mozaffari H; Darooghegi Mofrad M; Surkan PJ; Askari M; Azadbakht L · Public health nutrition · 2021
    Cross-sectional study447 participantsStress Relief forVitamin B6