Product Image

Pulse Fruit Punch

Legion
4.8
★ ★ ★ ★ ★
(46 ratings)
Theanine 350 mg
Caffeine 350 mg
Alpha-GPC 300 mg
Product Image
Score77
A comprehensively dosed pre-workout with strong pump, endurance, betaine, Alpha-GPC, theanine, and electrolyte support. High caffeine and premium cost limit its audience.
How scoring works
Quantity:498 Gram(s) • (21 servings)
Goals:
Energy
Fitness
Muscle Gain
Mental Focus
Brain Health
Productivity Boost
Weight Loss
Metabolism Boost

Score 77

A comprehensively dosed pre-workout with strong pump, endurance, betaine, Alpha-GPC, theanine, and electrolyte support. High caffeine and premium cost limit its audience.
How scoring works
$44.99($2.14 per serving)
iHerb
$ 44.99
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Analysis

Citrulline malate reaches 8 g, beta-alanine 3.6 g, and betaine 2.5 g, giving the performance side credible depth. AlphaSize Alpha-GPC at 300 mg and theanine at 350 mg add focused cognitive and stimulant-balancing support.

Caffeine anhydrous is high at 350 mg even with an equal theanine amount. Sodium, potassium, and calcium add useful electrolyte coverage, but the six grams of carbohydrate are secondary to the active formula.

The fully disclosed powder is one of the most complete pre-workouts in the group. It fits demanding training for caffeine-tolerant adults, while sensitive users would benefit from a lower-stimulant option or a carefully reduced serving.

Who is it for
  • Experienced athletes with strong caffeine tolerance
  • Adults wanting a fully dosed all-in-one pre-workout
  • People who train well before bedtime
Best for
  • High-intensity performance sessions
  • Pump and muscular-endurance support
  • Workout focus with theanine and Alpha-GPC

Pros

  • Provides 8 g citrulline malate
  • Uses full-scale beta-alanine and betaine amounts
  • Includes 350 mg theanine and 300 mg Alpha-GPC
  • Adds sodium and potassium
  • Fully discloses active doses

Cons

  • Contains 350 mg caffeine
  • High serving cost
  • Limited dose flexibility for caffeine-sensitive users
  • Adds 6 g carbohydrate

Warnings

  • Do not combine the 350 mg caffeine serving with other stimulants or high-caffeine drinks
  • Avoid late-day use because caffeine may significantly disrupt sleep
  • Beta-alanine commonly causes temporary skin tingling
  • People with cardiovascular conditions, uncontrolled blood pressure, or stimulant sensitivity should seek professional guidance before use

Nutrient quality

85 Highest impact

Full pre-workout amounts of citrulline malate, beta-alanine, betaine, theanine, Alpha-GPC, and caffeine create excellent performance depth. The caffeine load is very high for stimulant-sensitive users.

.

Ingredient transparency

90 Highest impact

Individual active weights are clearly disclosed. Some extract percentages, enzyme activity, or non-active label details remain incomplete.

.

Customer satisfaction

63 Moderate impact

The supplied rating is favorable, but the feedback base is comparatively small. No complaint-level evidence was supplied to assess recurring issues or purpose-specific experiences.

.

Value for money

63 Moderate impact

The serving cost is high relative to the certainty provided by the label. Substantial ingredients help, but disclosure gaps weaken category competitiveness.

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Report analysis

Goals

Energy
Physical Stamina
Energy
Impact
Highest effect
A+ Goal FitA+ Strength of SupportA CoverageA+ Formula Quality
Potassium · 345 mgCaffeine · 350 mg

Caffeine and theanine provide powerful acute alertness support, while citrulline, beta-alanine, and betaine target workout performance. Each major active is supplied at a clearly stated, substantial amount.

The caffeine serving is very high and may cause anxiety, palpitations, sleep disruption, or other stimulant effects in sensitive users. The formula is tightly built for pre-workout energy rather than everyday fatigue management.

Study evidence
Caffeine Supportive 68 studies
Theanine Not classified

No linked studies yet.

Fitness
Strength and Power Output
Fitness
Impact
Highest effect
A+ Goal FitA+ Strength of SupportA+ CoverageA+ Formula Quality
Betaine Anhydrous · 2.5 Gram(s)Beta-Alanine · 3.6 Gram(s)Caffeine · 350 mg

Citrulline malate, beta-alanine, betaine, caffeine, and electrolytes provide unusually complete pre-workout coverage. Each main active reaches a well-supported amount, while L-theanine balances the strong stimulant component.

The caffeine amount is high enough to cause jitters, sleep disruption, or cardiovascular symptoms in many users. It is a potent formula for experienced caffeine users, but the serving is not appropriate for everyone.

Study evidence
Caffeine Supportive 255 studies
Muscle Gain
Muscle Gain
Impact
Highest effect
A Goal FitA Strength of SupportA CoverageA- Formula Quality
Caffeine · 350 mgBeta-Alanine · 3.6 Gram(s)

Fully dosed citrulline malate, beta-alanine, and betaine strongly support training volume and performance relevant to muscle gain. These main ergogenics have robust human evidence, while caffeine further supports acute output rather than hypertrophy directly.

The major pump, fatigue-buffering, and betaine amounts meet common evidence-based targets. The actives are logically paired and theanine may soften the subjective stimulant feel. The high caffeine amount may cause jitteriness or disrupt sleep, even with theanine present.

Study evidence
Caffeine Supportive 31 studies
Mental Focus
Mental Focus
Impact
Highest effect
A Goal FitA Strength of SupportA- CoverageA Formula Quality
Alpha-GPC · 300 mgTheanine · 350 mgCaffeine · 350 mg

Caffeine, L-theanine, and branded Alpha-GPC directly target alertness, calmness, and acetylcholine support. The combination is well constructed for acute focus, although 350 mg caffeine is a very high single-serving stimulant load.

All major active amounts are disclosed, and theanine matches caffeine one for one to soften its subjective edge. The high caffeine amount may cause anxiety, insomnia, palpitations, or blood-pressure increases, especially in stimulant-sensitive users or when combined with other caffeine.

Study evidence
Alpha-GPC Supportive 1 study
Caffeine Supportive 128 studies
Theanine Supportive 19 studies
Brain Health
Brain Health
Impact
Highest effect
A- Goal FitA Strength of SupportB+ CoverageA- Formula Quality
Alpha-GPC · 300 mg

Caffeine, L-theanine, and branded Alpha-GPC create a direct focus and acetylcholine-support combination. Performance ingredients may further support training energy but are secondary to the cognitive trio.

Theanine and caffeine are substantial, while the Alpha-GPC label does not state active yield. The 350 mg caffeine amount may cause jitteriness, rapid heartbeat, anxiety, or sleep disruption in stimulant-sensitive users.

Study evidence
Alpha-GPC Supportive 12 studies
Theanine Supportive 17 studies
Productivity Boost
Productivity Boost
Impact
Highest effect
A Goal FitA- Strength of SupportA- CoverageB+ Formula Quality
Alpha-GPC · 300 mgTheanine · 350 mgCaffeine · 350 mg

Caffeine, L-theanine, and Alpha-GPC form a strong stack for alertness, smoother stimulation, and cholinergic support. The product is built for exercise, but the core trio is directly relevant to productivity.

The caffeine amount is very high, while theanine is also higher than usually needed and Alpha-GPC active yield is unclear. Exercise ingredients add bulk, yet the main cognitive combination remains coherent and potent.

Study evidence
Alpha-GPC Supportive 2 studies
Caffeine Supportive 108 studies
Theanine Supportive 5 studies

Ingredients

IngredientAmount per serving
Calories
10 Calorie(s)
Total Carbohydrates
6 Gram(s)
Calcium
148 mg
Sodium (Sodium Citrate)
 230 mg
Potassium (Tripotassium Citrate)
 345 mg
L-Citrulline DL-Malate
8 Gram(s)
CarnoSyn (Beta-Alanine)
 3.6 Gram(s)
Betaine Anhydrous
2.5 Gram(s)
Caffeine Anhydrous
350 mg
L-Theanine
350 mg
Alphasize Alpha-Glyceryl Phosphoryl Choline
300 mg
Adults 18–50 Women
Report overview
Theanine · 350 mg OverallScore68
B+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

Explicit L-theanine identity confirms the active isomer, but no branded source or purity testing is shown. The higher amount remains within a generally safe range but may feel more sedating than needed. A large stimulant amount makes the formula better aligned with focused energy than relaxation.

View ingredientView products
Caffeine · 350 mg OverallScore64
B Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyF Value

Caffeine anhydrous is clearly measured at 350 mg, but the amount is very high for one serving. L-theanine may soften the subjective feel without reducing the stimulant exposure, and no sustained-release form is used. The narrow safety margin and very high serving cost limit its appeal.

View ingredientView products
Alpha-GPC · 300 mg OverallScore60
C+ Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyD- Value

AlphaSize provides a recognized branded form, but the listed 300 mg does not clarify active yield. Assuming 50% yield, the estimated 150 mg active amount fits a lower maintenance range. The 350 mg caffeine amount may cause jitteriness or disrupt sleep, especially in stimulant-sensitive users.

View ingredientView products
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68 Performance

Prolific Pre-Workout Cotton Candy

PEScience
Citrulline, betaine, taurine, citicoline, theanine, rhodiola, and coffee-fruit extract create broad workout and focus support. The unclear split between two caffeine entries is a serious limitation despite the well-developed non-stimulant base.
71 Performance

High-Performance Pre-Workout Black Cherry

Pre JYM
Citrulline malate, amino acids, tyrosine, caffeine, creatine, and taurine provide wider training support than a focus-led formula. Some actives are modest, and strong caffeine combined with huperzine may be unsuitable for sensitive users.
60 Performance

C4 Ultimate Icy Blue Razz

Nutrabolt
Full beta-alanine plus pump ingredients, creatine, taurine, and caffeine create substantial acute workout support. Alpha-GPC is modest and caffeine combined with theacrine and rauwolfia increases stimulant-related safety trade-offs.
66 Budget

Bucked Up Pre-Workout 'Merica Rocket Pop

DAS Labs
Citrulline malate, beta-alanine, caffeine, and Alpha-GPC preserve the main pre-workout roles at better serving economics. Beta-alanine and Alpha-GPC are less fully dosed, and several small botanical additions add complexity without clear practical benefit.
72 Budget

Seventh Gear Your Mom's Lemonade

Axe & Sledge Supplements
Multiple stimulant forms plus beta-alanine, betaine, creatine, and Alpha-GPC provide broad energy and workout support at favorable value. Most performance ingredients are modestly dosed, and the stimulant stack may disrupt sleep or cause jitters.
73 Budget

Nitrosurge Shred Orange Pineapple

Jacked Factory JF
Caffeine, theanine, acetyl-L-carnitine, citrulline, and beta-alanine cover energy, focus, and exercise at lower serving cost. Citrulline and beta-alanine are less substantial than the original amounts, limiting performance depth.
64 Value

Pre-Workout Blue Raz

Bucked Up
A substantial citrulline amount and moderate caffeine retain the core pre-workout effect with better serving economics. Beta-alanine and Alpha-GPC are modest, while several small extras contribute little to the main goals.
70 Value

High-Performance Pre-Workout Strawberry Kiwi

Pre JYM
Citrulline, branched-chain amino acids, tyrosine, caffeine, creatine, and taurine provide broad performance coverage with fully listed amounts. Several key actives remain modest, but the formula offers useful depth for its serving value.
74 Value

Nitrosurge Shred Black Cherry

Jacked Factory
A balanced caffeine-theanine pairing joins acetyl-L-carnitine and core workout ingredients at better serving economics. Citrulline and beta-alanine are below the original amounts, so the trade-off is reduced exercise support.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of caffeine ingestion on time trial performance in cyclists: a systematic review and meta-analysis.
    Chen B; Ding L; Qin Q; Lei TH; Girard O; Cao Y · Journal of the International Society of Sports Nutrition · 2024
    Meta-analysis15 studies pooledFitness forCaffeine
  2. Promising, but Not Completely Conclusive-The Effect of l-Theanine on Cognitive Performance Based on the Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Trials.
    Mátyus RO; Szikora Z; Bodó D; Vargáné Szabó B; Csupor É; Csupor D; Tóth B · Journal of clinical medicine · 2025
    Meta-analysis148 participants5 studies pooledMental Focus Cognitive Support forTheanine
  3. L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial.
    Sarris J; Byrne GJ; Cribb L; Oliver G; Murphy J; Macdonald P; Nazareth S; Karamacoska D; Galea S; Short A; Ee C; Birling Y; Menon R; Ng CH · Journal of psychiatric research · 2020
    Randomized trial46 participantsStress Relief forTheanine
  4. Effect of Choline Alfoscerate on the Progression From Mild Cognitive Impairment to Dementia: Distributed Network Analysis of a Multicenter Korean Database Using a Common Data Model.
    Pyun JM; Lee I; Lee K; Kim MH; Park C; Yang HJ · Dementia and neurocognitive disorders · 2024
    Cohort study3,062 participantsCognitive Support forAlpha-GPC
  5. No effects of caffeine on cycling to exhaustion and perceptual responses in non-caffeine-restricted subjects.
    Weippert M; Behrens M; Schlegel M; Schröder T; Tillmann M; Rühe N; Römer R; Mau-Möller A; Bruhn S · Journal of the International Society of Sports Nutrition · 2025
    Randomized trial56 participantsFitness forCaffeine
  6. Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together.
    Rogers PJ; Smith JE; Heatherley SV; Pleydell-Pearce CW · Psychopharmacology · 2008
    Randomized trial48 participantsMental Focus Cognitive Support Productivity Boost forTheanine
  7. A double-blind, placebo-controlled study evaluating the effects of caffeine and L-theanine both alone and in combination on cerebral blood flow, cognition and mood.
    Dodd FL; Kennedy DO; Riby LM; Haskell-Ramsay CF · Psychopharmacology · 2016
    Randomized trial24 participantsCognitive Support Mental Focus forTheanine
  8. Effect of Combined Ingestion of L-Theanine and L-Arginine for Short-Term Psychological Stress in Young Adults: A Randomized Placebo-Controlled Study.
    Furushima D; Sugiyama I; Nomura Y; Unno K; Yamada H · Journal of nutritional science and vitaminology · 2023
    Randomized trial120 participantsStress Relief forTheanine
  9. The Care Pathway for Patients with Mild Cognitive Impairment in Korea: A Survey of Dementia Specialists.
    Choi SH; Shim Y; Kim S; Yang DW; Park KH; Kim J; Youn YC · Dementia and geriatric cognitive disorders extra · 2025
    Cross-sectional studyCognitive Support forAlpha-GPC
  10. Effect of caffeine ingestion on cycling performance: a systematic review and meta-analysis.
    Wu J; Xu K; Yin M; Ding X; Wang T; Zhang Q; Wu X; Xiao N · Frontiers in nutrition · 2026
    Meta-analysis226 participants20 studies pooledFitness forCaffeine
  11. Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial.
    White DJ; de Klerk S; Woods W; Gondalia S; Noonan C; Scholey AB · Nutrients · 2016
    Randomized trial34 participantsStress Relief forTheanine
  12. Comparative study of choline alfoscerate as a combination therapy with donepezil: A mixed double-blind randomized controlled and open-label observation trial.
    Lee W; Kim M · Medicine · 2024
    Randomized trial119 participantsCognitive Support Brain Health forAlpha-GPC
  13. Effects of Caffeine Intake on Endurance Running Performance and Time to Exhaustion: A Systematic Review and Meta-Analysis.
    Wang Z; Qiu B; Gao J; Del Coso J · Nutrients · 2023
    Meta-analysis254 participants21 studies pooledFitness forCaffeine
  14. Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Payne ER; Aceves-Martins M; Dubost J; Greyling A; de Roos B · Nutrition reviews · 2025
    Meta-analysis50 studies pooledMental Focus Cognitive Support Brain Health forTheanine
  15. Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task.
    Foxe JJ; Morie KP; Laud PJ; Rowson MJ; de Bruin EA; Kelly SP · Neuropharmacology · 2012
    Randomized trial27 participantsCognitive Support Brain Health forTheanine
  16. Safety and Efficacy of AlphaWave® L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Moulin M; Crowley DC; Xiong L; Guthrie N; Lewis ED · Neurology and therapy · 2024
    Randomized trial30 participantsStress Relief Mental Focus Productivity Boost forTheanine
  17. Activity of Choline Alphoscerate on Adult-Onset Cognitive Dysfunctions: A Systematic Review and Meta-Analysis.
    Sagaro GG; Traini E; Amenta F · Journal of Alzheimer's disease : JAD · 2023
    Meta-analysis8 studies pooledCognitive Support Brain Health forAlpha-GPC
  18. Caffeine, CYP1A2 Genotype, and Endurance Performance in Athletes.
    Guest N; Corey P; Vescovi J; El-Sohemy A · Medicine and science in sports and exercise · 2019
    Randomized trial101 participantsFitness forCaffeine
  19. Dose-response effect of L-theanine on psychomotor speed, sustained attention, and inhibitory control: a double-blind, placebo-controlled, crossover study.
    Dassanayake TL; Wijesundara D; Kahathuduwa CN; Weerasinghe VS · Nutritional neuroscience · 2023
    Randomized trial32 participantsCognitive Support Mental Focus forTheanine
  20. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
    Hidese S; Ogawa S; Ota M; Ishida I; Yasukawa Z; Ozeki M; Kunugi H · Nutrients · 2020
    Randomized trial30 participantsCognitive Support Stress Relief Brain Health forTheanine
  21. Effects of choline alfoscerate on cognitive function and quality of life in type 2 diabetes: A double-blind, randomized, placebo-controlled trial.
    Sohn M; Park YH; Lim S · Diabetes, obesity & metabolism · 2025
    Randomized trial36 participantsCognitive Support Brain Health forAlpha-GPC
  22. Placebo in sports nutrition: a proof-of-principle study involving caffeine supplementation.
    Saunders B; de Oliveira LF; da Silva RP; de Salles Painelli V; Gonçalves LS; Yamaguchi G; Mutti T; Maciel E; Roschel H; Artioli GG; Gualano B · Scandinavian journal of medicine & science in sports · 2018
    Randomized trial42 participantsFitness forCaffeine
  23. Acute effects of theanine, caffeine and theanine-caffeine combination on attention.
    Kahathuduwa CN; Dassanayake TL; Amarakoon AMT; Weerasinghe VS · Nutritional neuroscience · 2018
    Clinical trial20 participantsMental Focus Cognitive Support forTheanine
  24. Effects of L-theanine or caffeine intake on changes in blood pressure under physical and psychological stresses.
    Yoto A; Motoki M; Murao S; Yokogoshi H · Journal of physiological anthropology · 2013
    Randomized trial14 participantsStress Relief forTheanine
  25. [Gliatilin in the Treatment of Cognitive Impairments Not Reaching the Level of Dementia: Meta-Analysis and Systematic Review].
    Voznyuk IA; Nepomnyashchiy IS; Kutkova AK; Tokareva DV; Prokhorova MV; Ovdiienko OA; Shusharina NN · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2025
    Meta-analysis10 studies pooledCognitive Support forAlpha-GPC
  26. Acute Effects of Caffeine Supplementation on Movement Velocity in Resistance Exercise: A Systematic Review and Meta-analysis.
    Raya-González J; Rendo-Urteaga T; Domínguez R; Castillo D; Rodríguez-Fernández A; Grgic J · Sports medicine (Auckland, N.Z.) · 2021
    Meta-analysis12 studies pooledFitness forCaffeine
  27. Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study.
    Baba Y; Inagaki S; Nakagawa S; Kaneko T; Kobayashi M; Takihara T · Journal of medicinal food · 2021
    Randomized trialMental Focus Cognitive Support Brain Health Productivity Boost forTheanine
  28. A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWave® L-Theanine on Stress in a Healthy Adult Population.
    Evans M; McDonald AC; Xiong L; Crowley DC; Guthrie N · Neurology and therapy · 2021
    Randomized trialStress Relief Brain Health forTheanine
  29. Vertical Association Between Dietary Total Choline and L-alpha-glycerylphosphorylcholine and the Cognitive Function in Chinese Adults Aged over 55, Result from China Health and Nutrition Survey 1997-2018.
    Guan F; Jia X; Huang F; Zhang J; Wei Y; Li L; Bai J; Wang H · Nutrients · 2024
    Cohort study7,659 participantsCognitive Support forAlpha-GPC
  30. Acute Effects of Caffeine Supplementation on Physical Performance, Physiological Responses, Perceived Exertion, and Technical-Tactical Skills in Combat Sports: A Systematic Review and Meta-Analysis.
    Delleli S; Ouergui I; Messaoudi H; Trabelsi K; Ammar A; Glenn JM; Chtourou H · Nutrients · 2022
    Meta-analysis26 studies pooledFitness forCaffeine
  31. Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
    Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK · Journal of anaesthesiology, clinical pharmacology · 2025
    Randomized trial168 participantsStress Relief Mood Support forTheanine
  32. A multicentre trial to evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia.
    Di Perri R; Coppola G; Ambrosio LA; Grasso A; Puca FM; Rizzo M · The Journal of international medical research · 1991
    Randomized trial120 participantsCognitive Support forAlpha-GPC
  33. Can I Have My Coffee and Drink It? A Systematic Review and Meta-analysis to Determine Whether Habitual Caffeine Consumption Affects the Ergogenic Effect of Caffeine.
    Carvalho A; Marticorena FM; Grecco BH; Barreto G; Saunders B · Sports medicine (Auckland, N.Z.) · 2022
    Meta-analysis60 studies pooledFitness forCaffeine
  34. Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study.
    Karunaratne UW; Dassanayake TL · Nutritional neuroscience · 2025
    Randomized trial24 participantsMental Focus forTheanine
  35. L-theanine improves neurophysiological measures of attention in a dose-dependent manner: a double-blind, placebo-controlled, crossover study.
    Dassanayake TL; Kahathuduwa CN; Weerasinghe VS · Nutritional neuroscience · 2022
    Randomized trial27 participantsMental Focus Cognitive Support forTheanine
  36. The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review.
    Williams JL; Everett JM; D'Cunha NM; Sergi D; Georgousopoulou EN; Keegan RJ; McKune AJ; Mellor DD; Anstice N; Naumovski N · Plant foods for human nutrition (Dordrecht, Netherlands) · 2020
    Systematic review9 studies pooledStress Relief Mood Support forTheanine
  37. [Efficacy of choline alfoscerate treatment for subjective cognitive impairment in first-degree relatives of patients with Alzheimer's disease: Results of a comparative 5-year study].
    Selezneva ND; Roshchina IF; Gavrilova SI · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2026
    Non-randomized trial122 participantsCognitive Support forAlpha-GPC
  38. Sex Differences in the Ergogenic Response of Acute Caffeine Intake on Muscular Strength, Power and Endurance Performance in Resistance-Trained Individuals: A Randomized Controlled Trial.
    Montalvo-Alonso JJ; Ferragut C; Del Val-Manzano M; Valadés D; Roberts J; Pérez-López A · Nutrients · 2024
    Randomized trial76 participantsFitness forCaffeine
  39. L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study.
    Ritsner MS; Miodownik C; Ratner Y; Shleifer T; Mar M; Pintov L; Lerner V · The Journal of clinical psychiatry · 2011
    Randomized trial60 participantsStress Relief Mood Support forTheanine
  40. [Modern approaches to the diagnostics and treatment of the consequences of traumatic brain injury in children and adolescents].
    Nemkova SA · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2022
    Randomized trialCognitive Support forAlpha-GPC
  41. Acute Alpha-Glycerylphosphorylcholine Supplementation Enhances Cognitive Performance in Healthy Men.
    Kerksick CM · Nutrients · 2024
    Randomized trial20 participantsBrain Health Mental Focus Productivity Boost forAlpha-GPC
  42. Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial.
    De Jesus Moreno Moreno M · Clinical therapeutics · 2003
    Randomized trial261 participantsBrain Health forAlpha-GPC
  43. Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine.
    Haskell CF; Kennedy DO; Wesnes KA; Scholey AB · Psychopharmacology · 2005
    Randomized trial48 participantsEnergy forCaffeine
  44. Caffeine-containing energy drink improves physical performance of elite rugby players during a simulated match.
    Del Coso J; Ramírez JA; Muñoz G; Portillo J; Gonzalez-Millán C; Muñoz V; Barbero-Álvarez JC; Muñoz-Guerra J · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2016
    Randomized trial26 participantsEnergy forCaffeine
  45. Differential cognitive effects of energy drink ingredients: caffeine, taurine, and glucose.
    Giles GE; Mahoney CR; Brunyé TT; Gardony AL; Taylor HA; Kanarek RB · Pharmacology, biochemistry, and behavior · 2013
    Randomized trial48 participantsEnergy forCaffeine
  46. Does Single or Combined Caffeine and Taurine Supplementation Improve Athletic and Cognitive Performance without Affecting Fatigue Level in Elite Boxers? A Double-Blind, Placebo-Controlled Study.
    Ozan M; Buzdagli Y; Eyipinar CD; Baygutalp NK; Yüce N; Oget F; Kan E; Baygutalp F · Nutrients · 2022
    Randomized trial20 participantsEnergy forCaffeine
  47. Trait Energy and Fatigue Modify the Effects of Caffeine on Mood, Cognitive and Fine-Motor Task Performance: A Post-Hoc Study.
    Fuller DT; Smith ML; Boolani A · Nutrients · 2021
    Randomized trialEnergy forCaffeine
  48. Effects of modafinil and caffeine on night-time vigilance of air force crewmembers: A randomized controlled trial.
    Wingelaar-Jagt YQ; Bottenheft C; Riedel WJ; Ramaekers JG · Journal of psychopharmacology (Oxford, England) · 2023
    Randomized trial32 participantsMental Focus forCaffeine
  49. Acute effects of caffeine on attention: a comparison of non-consumers and withdrawn consumers.
    Smith AP; Christopher G; Sutherland D · Journal of psychopharmacology (Oxford, England) · 2013
    Randomized trial70 participantsMental Focus forCaffeine
  50. Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.
    Wesensten NJ; Killgore WD; Balkin TJ · Journal of sleep research · 2006
    Randomized trial48 participantsMental Focus forCaffeine
  51. Effects of caffeine on mood and performance: a study of realistic consumption.
    Brice CF; Smith AP · Psychopharmacology · 2003
    Clinical trial24 participantsMental Focus forCaffeine
  52. Effects of caffeine or diphenhydramine on visual vigilance.
    Fine BJ; Kobrick JL; Lieberman HR; Marlowe B; Riley RH; Tharion WJ · Psychopharmacology · 1995
    Randomized trial24 participantsMental Focus forCaffeine
  53. A Randomized Study to Examine the Ability of a Caffeine-Based Energy Drink to Impact Energy Expenditure, Fat Oxidation, and Cognitive Performance.
    Krieger J; Schrautemeier A; Hagele A; Gaige C; Mennemeyer O; Tolbert S; Iannotti J; Kerksick C; Noonan C; Mumford P · Nutrients · 2025
    Randomized trial60 participantsMetabolism Boost forCaffeine
  54. Oolong tea increases metabolic rate and fat oxidation in men.
    Rumpler W; Seale J; Clevidence B; Judd J; Wiley E; Yamamoto S; Komatsu T; Sawaki T; Ishikura Y; Hosoda K · The Journal of nutrition · 2001
    Randomized trial12 participantsMetabolism Boost forCaffeine
  55. Effect of caffeine intake on fat oxidation rate during exercise: is there a dose-response effect?
    Gutiérrez-Hellín J; Aguilar-Navarro M; Ruiz-Moreno C; Muñoz A; Varillas-Delgado D; Amaro-Gahete FJ; Del Coso J · European journal of nutrition · 2023
    Randomized trial18 participantsMetabolism Boost forCaffeine
  56. Comparison of changes in energy expenditure and body temperatures after caffeine consumption.
    Koot P; Deurenberg P · Annals of nutrition & metabolism · 1995
    Randomized trial12 participantsMetabolism Boost forCaffeine
  57. Caffeine Increases Work Done above Critical Power, but Not Anaerobic Work.
    Silveira R; Andrade-Souza VA; Arcoverde L; Tomazini F; Sansonio A; Bishop DJ; Bertuzzi R; Lima-Silva AE · Medicine and science in sports and exercise · 2018
    Randomized trial9 participantsMetabolism Boost forCaffeine
  58. Association Between the Cholinesterase Inhibitor Donepezil and the Cholinergic Precursor Choline Alphoscerate in the Treatment of Depression in Patients with Alzheimer's Disease
    Anna Carotenuto, Angiola Maria Fasanaro, Valentino Manzo, Francesco Amenta, Enea Traini · Journal of Alzheimer's disease reports · 2022
    Randomized trial90 participantsMood Support forAlpha-GPC
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  60. Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activity, trait anxiety and subjective stress.
    Unno K; Tanida N; Ishii N; Yamamoto H; Iguchi K; Hoshino M; Takeda A; Ozawa H; Ohkubo T; Juneja LR; Yamada H · Pharmacology, biochemistry, and behavior · 2014
    Randomized trial20 participantsMood Support forTheanine
  61. Effects of Acute Ingestion of Caffeine Capsules on Muscle Strength and Muscle Endurance: A Systematic Review and Meta-Analysis.
    Wu W; Chen Z; Zhou H; Wang L; Li X; Lv Y; Sun T; Yu L · Nutrients · 2024
    Meta-analysis14 studies pooledMuscle Gain forCaffeine
  62. Acute caffeine intake improves muscular strength, power, and endurance performance, reversing the time-of-day effect regardless of muscle activation level in resistance-trained males: a randomized controlled trial.
    Montalvo-Alonso JJ; Del Val-Manzano M; Cerezo-Telléz E; Ferragut C; Valadés D; Rodríguez-Falces J; Pérez-López A · European journal of applied physiology · 2025
    Randomized trial13 participantsMuscle Gain forCaffeine
  63. Wake up and smell the coffee: caffeine supplementation and exercise performance-an umbrella review of 21 published meta-analyses.
    Grgic J; Grgic I; Pickering C; Schoenfeld BJ; Bishop DJ; Pedisic Z · British journal of sports medicine · 2020
    Systematic review21 studies pooledMuscle Gain forCaffeine
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    Grgic J; Trexler ET; Lazinica B; Pedisic Z · Journal of the International Society of Sports Nutrition · 2018
    Meta-analysis20 studies pooledMuscle Gain forCaffeine
  65. Caffeine increases strength and power performance in resistance-trained females during early follicular phase.
    Norum M; Risvang LC; Bjørnsen T; Dimitriou L; Rønning PO; Bjørgen M; Raastad T · Scandinavian journal of medicine & science in sports · 2021
    Randomized trial15 participantsMuscle Gain forCaffeine
  66. Treatment of dementia with neurotransmission modulation.
    Doggrell SA; Evans S · Expert opinion on investigational drugs · 2004
    Narrative reviewProductivity Boost forAlpha-GPC
  67. Effects of caffeine on alertness.
    Zwyghuizen-Doorenbos A; Roehrs TA; Lipschutz L; Timms V; Roth T · Psychopharmacology · 1990
    Randomized trial24 participantsProductivity Boost forCaffeine
  68. Effects of Different Sources of Low-Dose Caffeine on Mood/Arousal and Cognitive Performance.
    Irwin C; McCartney D; Grant G; Delang N; Bartrim K; Cox GR; Desbrow B · Perceptual and motor skills · 2023
    Randomized trial22 participantsProductivity Boost forCaffeine
  69. Effects of caffeine, sleep loss, and stress on cognitive performance and mood during U.S. Navy SEAL training. Sea-Air-Land.
    Lieberman HR; Tharion WJ; Shukitt-Hale B; Speckman KL; Tulley R · Psychopharmacology · 2003
    Randomized trial68 participantsProductivity Boost forCaffeine
  70. A review of caffeine's effects on cognitive, physical and occupational performance.
    McLellan TM; Caldwell JA; Lieberman HR · Neuroscience and biobehavioral reviews · 2017
    Narrative reviewProductivity Boost forCaffeine
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    Wang R; Wang W; Meng L; Hao G; Gu G · Frontiers in nutrition · 2026
    Meta-analysis7 studies pooledProductivity Boost forCaffeine
  72. Cognitive and affective effects of L-Theanine: a systematic review and meta-analysis of 31 randomized trials.
    Gerolymos C; Saddier E; Boyer L; Fond G · Molecular psychiatry · 2026
    Meta-analysis1,168 participants31 studies pooledProductivity Boost forTheanine
  73. Effects of L-theanine on cognition, mood and sleep: evidence from human trials.
    Cotter J; Kilpatrick HE · Frontiers in nutrition · 2026
    Narrative reviewProductivity Boost forTheanine
  74. Changes in caffeine intake and long-term weight change in men and women.
    Lopez-Garcia E; van Dam RM; Rajpathak S; Willett WC; Manson JE; Hu FB · The American journal of clinical nutrition · 2006
    Cohort study58,157 participantsWeight Loss forCaffeine
  75. Does caffeine ingestion before a short-term sprint interval training promote body fat loss?
    Ferreira GA; Felippe LC; Bertuzzi R; Bishop DJ; Ramos IS; De-Oliveira FR; Lima-Silva AE · Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2020
    Randomized trial20 participantsWeight Loss forCaffeine
  76. Eight Weeks of Sprint Interval Training With Adding Caffeine Ingestion Leads to Greater Improvements in Health-Related Physiological Parameters in Obese Male Adults.
    Zhiang J; Song Q · Physiological research · 2026
    Randomized trial30 participantsWeight Loss forCaffeine
  77. Caffeine treatment prevented from weight regain after calorie shifting diet induced weight loss.
    Davoodi SH; Hajimiresmaiel SJ; Ajami M; Mohseni-Bandpei A; Ayatollahi SA; Dowlatshahi K; Javedan G; Pazoki-Toroudi H · Iranian journal of pharmaceutical research : IJPR · 2014
    Non-randomized trial60 participantsWeight Loss forCaffeine
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    Tabrizi R; Saneei P; Lankarani KB; Akbari M; Kolahdooz F; Esmaillzadeh A; Nadi-Ravandi S; Mazoochi M; Asemi Z · Critical reviews in food science and nutrition · 2020
    Meta-analysis606 participants13 studies pooledWeight Loss forCaffeine