Product Image

Whole-Food Multivitamin plus Vital Minerals for Women

Dr. Mercola
4.7
★ ★ ★ ★ ★
(821 ratings)
PABA 50 mg
Calcium 250 mg
Iodine 200 mcg
Vitamin C 500 mg
Niacin 40 mg
Papain 100 mg
Molybdenum 100 mcg
Product Image
Score68
A broad multivitamin with several good nutrient forms and meaningful mineral coverage. High-dose nutrients, an eight-tablet serving, and a proprietary blend reduce practicality and transparency.
How scoring works
Quantity:240 Tablet(s) • (30 servings)
Goals:
Bone Health
Immunity
General Health
Nail Health
Hair Health
Anti-Inflammatory Support
Detoxification
Cardiovascular Support

Score 68

A broad multivitamin with several good nutrient forms and meaningful mineral coverage. High-dose nutrients, an eight-tablet serving, and a proprietary blend reduce practicality and transparency.
How scoring works
$49.97($1.66 per serving)
iHerb
$ 54.99
Vitacost
$ 62.49
Amazon
$ 49.97
Pure Formulas
$ 49.99
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Analysis

The nutrient core includes methylfolate, methylcobalamin, pyridoxal 5-phosphate, riboflavin 5-phosphate, and several chelated minerals. Magnesium, vitamin C, zinc, selenium, and carotenoids give the formula broad general-health relevance.

An eight-tablet serving is a significant daily pill burden, and the women’s blend does not disclose each component amount. Numerous plant and enzyme extras are present at modest levels, making the long label look more substantial than its most useful components.

Vitamin D3 reaches 125 mcg, while vitamin E is also supplied in a high amount. The formula fits users who want an expansive multivitamin and accept careful stacking, but it is not a simple or flexible choice.

Who is it for
  • Women seeking an expansive multivitamin
  • Users who value active B-vitamin and chelated mineral forms
Best for
  • Broad micronutrient coverage
  • People comfortable with a high tablet count

Pros

  • Uses several active B-vitamin forms
  • Includes multiple chelated minerals
  • Broad antioxidant and carotenoid coverage
  • Meaningful magnesium and vitamin C amounts

Cons

  • Requires eight tablets per serving
  • Women’s blend hides individual component amounts
  • Many extras are included at modest doses
  • Difficult to combine with other fortified products

Warnings

  • Vitamin D3 at 125 mcg reaches the usual adult daily upper intake level and should be counted with other sources.
  • The high vitamin E amount may increase bleeding risk with anticoagulant or antiplatelet medicines.
  • Biotin at 900 mcg can interfere with some laboratory tests, so users should follow laboratory guidance before testing.

Nutrient quality

69 High impact

Bioactive vitamins and chelated minerals create a strong core nutrient profile. High potency and numerous modest extras reduce balance and focus.

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Ingredient transparency

73 High impact

Most nutrients have specific forms and amounts, with substantial disclosure across the blend. Repeated source entries, broad blend names, and missing tablet excipients make the label harder to evaluate.

.

Customer satisfaction

70 High impact

The aggregate rating is strong and supported by a large feedback count. No complaint-level evidence was supplied to identify recurring issues or confirm purpose-specific experiences.

.

Value for money

56 Moderate impact

Premium forms and unusually broad coverage provide some justification for the serving cost. A high tablet burden and many modest extras reduce practical competitiveness.

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Report analysis

Goals

Bone Health
Bone Health
Impact
Highest effect
A- Goal FitA Strength of SupportA- CoverageB- Formula Quality
Magnesium · 500 mgCalcium · 250 mgVitamin D · 125 mcgCopper · 0.05 mgManganese · 2 mgBoron · 1.5 mgZinc · 15 mgVitamin C · 500 mg

Substantial magnesium, vitamin D3, calcium, silica, boron, zinc, copper, manganese, and vitamin C provide broad skeletal support. Chelated magnesium and citrate-malate calcium are favorable forms.

Vitamin K is absent and calcium is only partial for a dedicated bone product. The 125 mcg vitamin D3 amount is high enough to warrant checking total vitamin D intake and personal monitoring needs.

Study evidence
Boron Supportive 5 studies
Calcium Supportive 144 studies
Copper Disputed 20 studies
Magnesium Supportive 48 studies
Manganese Adverse 12 studies
Vitamin C Supportive 46 studies
Vitamin D Supportive 202 studies
Zinc Supportive 33 studies
Immunity
Immunity
Impact
Highest effect
A Goal FitA- Strength of SupportB+ CoverageC Formula Quality
Magnesium · 500 mgVitamin C · 500 mgZinc · 15 mgVitamin A · 1500 mcgVitamin D · 125 mcgSelenium · 200 mcg

High vitamin C, vitamin D3, selenium, and a broad micronutrient base align strongly with immune support. The formula covers antioxidant control, barrier nutrients, and immune-cell micronutrient needs with substantial servings.

Some mineral forms remain only partly identified, bromelain is modest without activity units, and many whole-food extras add shallow breadth. The core nutrients are useful, but the large formula is less focused than a dedicated immune supplement.

Study evidence
Bromelain Not classified 1 study
Selenium Mixed 37 studies
Vitamin C Supportive 53 studies
General Health
General Health
Impact
Highest effect
A- Goal FitB+ Strength of SupportA- CoverageC Formula Quality
Folate · 1335 mcg DFEVitamin B12 · 100 mcgVitamin D · 125 mcgMagnesium · 500 mgBoron · 1.5 mgSelenium · 200 mcgZinc · 15 mgVitamin C · 500 mg

A wide nutrient base with active folate, methylcobalamin, vitamin D3, chelated minerals, and substantial magnesium supports many foundations of wellness. The formula reaches across nutritional gaps, energy metabolism, antioxidant protection, and mineral balance.

The eight-tablet serving includes a large blend and many small accessory ingredients that are less clearly useful. High vitamin D3 and magnesium amounts also warrant attention when combined with other supplements.

Study evidence
Folate Supportive 80 studies
Magnesium Supportive 114 studies
Vitamin B12 Adverse 66 studies
Nail Health
Nail Health
Impact
Highest effect
A- Goal FitB Strength of SupportA- CoverageC+ Formula Quality
Silicon · 100 mgBiotin · 900 mcg

The multivitamin is strongly aligned with nail strength through several structural and nutritional pathways. Silica, cysteine, N-acetyl cysteine, biotin, zinc, selenium, copper, and vitamin C support cross-linking, keratin building blocks, matrix growth, and antioxidant protection.

The silicon form is not well characterized and copper is only a trace amount. Broad nail coverage and meaningful doses make the formula much stronger than a typical multivitamin for this goal.

Study evidence
Biotin Supportive 8 studies
Selenium Adverse 1 study
Silicon Supportive 2 studies
Vitamin C Supportive 1 study
Zinc No effect 1 study
Hair Health
Hair Health
Impact
High effect
B+ Goal FitB+ Strength of SupportA- CoverageC+ Formula Quality
Biotin · 900 mcgVitamin D · 125 mcgZinc · 15 mgVitamin C · 500 mg

Silica, cysteine, biotin, zinc, vitamin D, selenium, iodine, and vitamin C create a broad hair-supportive profile. The combination supplies structural material alongside nutrients linked to follicle growth and antioxidant protection.

No iron or targeted hormone-modulating botanical is included, and copper is unusually low relative to zinc. Even so, the disclosed amounts give several pathways meaningful depth.

Study evidence
Biotin Supportive 4 studies
Copper Adverse 4 studies
Iodine No effect 1 study
Selenium Disputed 7 studies
Vitamin C Mixed 5 studies
Vitamin D Disputed 34 studies
Zinc Supportive 22 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
B+ Goal FitB Strength of SupportB+ CoverageC+ Formula Quality
Vitamin D · 125 mcgVitamin E · 134 mgVitamin C · 500 mg

High-dose vitamin D3, vitamin C, natural vitamin E, NAC, selenium, bromelain, and polyphenols cover several anti-inflammatory mechanisms. NAC and bromelain are moderate rather than fully targeted amounts.

Active B vitamins, mineral ascorbates, and chelated minerals strengthen form quality, while enzyme activity units and blend details are missing. The formula is broad and largely coherent, though its very long ingredient list reduces precision.

Study evidence
Bromelain Supportive 12 studies
Selenium Supportive 34 studies
Vitamin C Supportive 50 studies
Vitamin D Supportive 101 studies
Vitamin E Supportive 20 studies

Ingredients

IngredientAmount per serving
Calories
15 Calorie(s)
Total Carbohydrates
3 Gram(s)
Vitamin A (Beta-Carotene)
 1500 mcg
Vitamin C (Ascorbyl Palmitate, Calcium Ascorbate, Magnesium Ascorbate, Niacinamide Ascorbate)
 500 mg
Vitamin D3 (Cholecalciferol)
 125 mcg
Vitamin E (D-Alpha-Tocopheryl Succinate)
 134 mg
Thiamine (Thiamine Hydrochloride, Vitamin B1)
 3 mg
Riboflavin (Riboflavin 5-Phosphate, Vitamin B2)
 3.4 mg
Niacin (Niacinamide Ascorbate)
 40 mg
Vitamin B6 (Pyridoxal 5-Phosphate)
 4 mg
Folate ((6S)-5-Methyltetrahydrofolic Acid)
 1335 mcg DFE
Vitamin B12 (Methylcobalamin)
 100 mcg
Biotin
900 mcg
Pantothenic Acid (Calcium Pantothenate)
 30 mg
Choline (Choline Bitartrate, Choline Dihydrogen Citrate)
 140 mg
Calcium (Calcium Ascorbate, Calcium Citrate Malate)
 250 mg
Iodine (Kelp)
 200 mcg
Magnesium (Magnesium Amino Acid Chelate Complex, Magnesium Ascorbate)
 500 mg
Zinc (Zinc Amino Acid Chelate)
 15 mg
Selenium (Selenium Amino Acid Chelate)
 200 mcg
Copper (Copper Amino Acid Chelate)
 0.05 mg
Manganese (Manganese Amino Acid Chelate)
 2 mg
Chromium (Chromium Amino Acid Chelate)
 200 mcg
Molybdenum (Molybdenum Amino Acid Chelate Complex)
 100 mcg
Potassium Complex (Potassium Amino Acid Chelate, Potassium Krebs Chelate)
 100 mg
Dr. Mercola's Blend for Women's Health
1142 mg
L-Cysteine and N-Acetyl L-Cysteine
150 mg
Betaine (Betaine HCl)
 114 mg
Chlorella
100 mg
Inositol
100 mg
Lemon Bioflavonoid Complex
100 mg
Papain
100 mg
Rose Hips
100 mg
Silica
100 mg
Spirulina
100 mg
Apple Pectin
50 mg
Bromelain
50 mg
Grape seed extract and Pine bark extract blend (Proanthocyanidins)
 50 mg
PABA
50 mg
Hesperidin
35 mg
Rutin
25 mg
Glutamic Acid
20 mg
Lutein (Marigold)
 6 mg
Lycopene (Tomato)
 6 mg
Boron (Boron Amino Acid Chelate Complex)
 1.5 mg
Zeaxanthin (Marigold)
 1 mg
Strontium (Strontium Citrate)
 297 mcg
Trace Elements (Red Seaweed)
 100 mcg
Vanadium (Vanadium Amino Acid Chelate)
 50 mcg
Women 18–50
Report overview
PABA · 50 mg OverallScore82
A Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value

The clearly identified PABA amount fits a standard high-potency B-complex range. Standard immediate release is appropriate at this amount. The serving offers weak cost efficiency for the active amount delivered.

View ingredientView products
Calcium (Calcium Ascorbate, Calcium Citrate Malate) · 250 mg OverallScore77
A+ Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyF Value

The citrate-malate form offers favorable absorption potential. The serving amount supports general supplementation rather than high calcium needs on its own; no listed purity concern materially weakens the formulation. The high serving cost limits value.

View ingredientView products
Iodine (Kelp) · 200 mcg OverallScore71
C Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

Kelp supplies a useful maintenance amount of iodine, but no organic status or clean-water origin is disclosed. The eight-tablet serving is cumbersome and increases dosing complexity. Selenium adds thyroid-related value, though the serving remains expensive.

View ingredientView products
Loading alternative details
82 Performance

Multi for Men

MegaFood
<p>Active B vitamins, chelated minerals, vitamin K2, and meaningful choline provide a more focused multivitamin foundation than the original's long list of modest extras. Zinc is high relative to copper, and the men's positioning is an important fit limitation.</p>
81 Performance

Multi for Men

MegaFood
<p>Chelated minerals and active B-vitamin forms offer stronger ingredient quality than many of the original's less consequential additions. The zinc-to-copper balance deserves attention, and the formula is designed for men rather than women.</p>
82 Budget

Multi for Men

MegaFood
<p>The lower serving cost and broad nutrient coverage make this a more economical option. Active B vitamins, chelated minerals, vitamin K2, and meaningful choline improve form quality, although the men's formula is not tailored to the original women's positioning.</p>
81 Budget

Multi for Men

MegaFood
<p>The lower serving cost improves value while retaining broad multivitamin coverage. Active B vitamins, chelated minerals, vitamin K2, and choline are useful strengths, but the men's formula may not match users seeking a women-specific nutrient profile.</p>
82 Value

Multi for Men

MegaFood
<p>Higher-quality B-vitamin and mineral forms combine with a lower serving cost to improve practical value. Vitamin K2 and choline add substance, though high zinc relative to copper and the men-specific positioning remain trade-offs.</p>
81 Value

Multi for Men

MegaFood
<p>Broad coverage, active B vitamins, and chelated minerals provide better quality for the serving cost. The formula includes useful vitamin K2 and choline, but it may not suit someone who specifically needs a women-oriented multivitamin.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Vitamin C intake and multiple health outcomes: an umbrella review of systematic reviews and meta-analyses.
    Xu K; Peng R; Zou Y; Jiang X; Sun Q; Song C · International journal of food sciences and nutrition · 2022
    Meta-analysis76 studies pooledGeneral Health forVitamin C
  2. Vitamin C for the management of COVID-19: a systematic review and meta-analysis of randomized controlled trials.
    Abid H; Mushtaq I; Munir ABI; Shakil J; Vinjamuri S; Tadasare N; Kiran F; Muhammad Wali Mirza A; Fatima Khidri F; Shahid A; Ayyan M; Ehsan M; Cheema HA; Alsubari AMA; Sahra S; Siddiqi NI · Annals of medicine and surgery (2012) · 2026
    Meta-analysis9 studies pooledGeneral Health forVitamin C
  3. Effects of oral magnesium therapy on exercise tolerance, exercise-induced chest pain, and quality of life in patients with coronary artery disease.
    Shechter M; Bairey Merz CN; Stuehlinger HG; Slany J; Pachinger O; Rabinowitz B · The American journal of cardiology · 2003
    Randomized trial187 participantsGeneral Health forMagnesium
  4. Dietary Zinc Intake and All-Cause and Cardiovascular Mortality in Korean Middle-Aged and Older Adults.
    Kwon YJ; Lee HS; Park G; Yang J; Kim HM; Lee JW · Nutrients · 2023
    Cohort study143,050 participantsGeneral Health forZinc
  5. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  6. Selenium supplementation for the primary prevention of cardiovascular disease.
    Rees K; Hartley L; Day C; Flowers N; Clarke A; Stranges S · The Cochrane database of systematic reviews · 2013
    Meta-analysis19,715 participants12 studies pooledGeneral Health forSelenium
  7. Modification of lymphocyte DNA damage by carotenoid supplementation in postmenopausal women.
    Zhao X; Aldini G; Johnson EJ; Rasmussen H; Kraemer K; Woolf H; Musaeus N; Krinsky NI; Russell RM; Yeum KJ · The American journal of clinical nutrition · 2006
    Randomized trial37 participantsAnti-Aging forLycopene
  8. Associations of different isomeric forms of serum lycopene with cardiovascular disease and all-cause mortality.
    Zhang Y; Zhai X; Chai H; Liu K; Ma W; Li S; Zeng J; Yang M; Zhou F; Zheng S; Wu X; Xiang B; Cao J; Eshak ES; Jiang C · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2024
    Cohort study7,452 participantsAnti-Aging forLycopene
  9. Associations between dietary carotenoid and biological age acceleration: insights from NHANES 2009-2018.
    Chen X; He C; Yu W; Ma L; Gou S; Fu P · Biogerontology · 2024
    Cross-sectional study19,280 participantsAnti-Aging forLycopene
  10. Biological Aging Mediates the Associations Between Multiple Serum Micronutrients and All-Cause Mortality Among U.S. Adults.
    Bian C; Wang W; Wu Z; Zhang H; Wen C; Zhong K; Yang R; Zhong Q · Biological trace element research · 2026
    Cohort study6,387 participantsAnti-Aging forLycopene
  11. Topical lycopene emulgel significantly improves biophysical parameters of human skin.
    Sohail M; Muhammad Faran Ashraf Baig M; Akhtar N; Chen Y; Xie B; Li B · European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2022
    Clinical trialAnti-Aging Skin Health forLycopene
  12. Dietary Magnesium May Be Protective for Aging of Bone and Skeletal Muscle in Middle and Younger Older Age Men and Women: Cross-Sectional Findings from the UK Biobank Cohort.
    Welch AA; Skinner J; Hickson M · Nutrients · 2018
    Cross-sectional study156,575 participantsAnti-Aging forMagnesium
  13. Higher Magnesium Intake Is Associated with a Lower Risk of Frailty in Older Adults.
    Dominguez LJ; Mérida DM; Donat-Vargas C; Banegas JR; Veronese N; Barbagallo M; Rodríguez-Artalejo F; Guallar-Castillón P · Journal of the American Medical Directors Association · 2024
    Cohort study1,900 participantsAnti-Aging forMagnesium
  14. Ca:Mg Ratio, APOE Cytosine Modifications, and Cognitive Function: Results from a Randomized Trial.
    Zhu X; Borenstein AR; Zheng Y; Zhang W; Seidner DL; Ness R; Murff HJ; Li B; Shrubsole MJ; Yu C; Hou L; Dai Q · Journal of Alzheimer's disease : JAD · 2021
    Randomized trial250 participantsAnti-Aging forMagnesium
  15. The Association between Dietary Nutrient Intake and Acceleration of Aging: Evidence from NHANES.
    Ma J; Li P; Jiang Y; Yang X; Luo Y; Tao L; Guo X; Gao B · Nutrients · 2024
    Cross-sectional study4,692 participantsAnti-Aging forMagnesium
  16. Interpretable machine learning with SHAP analysis identifies redox-modulating dietary antioxidants for predicting accelerated biological aging.
    Zhang B; Zhang X; Ma L; Li D; Li Y; Lin S; Peng L; He L · Experimental gerontology · 2026
    Cross-sectional study8,125 participantsAnti-Aging forMagnesium
  17. Selenium Concentrations and Mortality among Community-Dwelling Older Adults: Results from IlSIRENTE Study.
    Giovannini S; Onder G; Lattanzio F; Bustacchini S; Di Stefano G; Moresi R; Russo A; Bernabei R; Landi F · The journal of nutrition, health & aging · 2019
    Cohort study347 participantsAnti-Aging forSelenium
  18. Selenium and mortality in the elderly: results from the EVA study.
    Akbaraly NT; Arnaud J; Hininger-Favier I; Gourlet V; Roussel AM; Berr C · Clinical chemistry · 2005
    Randomized trialAnti-Aging forSelenium
  19. Association of dietary selenium intake and all-cause mortality of Parkinson's disease and its interaction with blood cadmium level: a retrospective cohort study.
    Tu X; Wu N; Wan Y; Gan J; Liu Z; Song L · BMC geriatrics · 2024
    Cohort study184 participantsAnti-Aging forSelenium
  20. Selenium alleviates cadmium-induced biological aging acceleration and the potential mediating role of inflammation.
    Li C; Xiang Y; Liu M; Wang Z; Wu Y; Yang Q; Huang L · Ecotoxicology and environmental safety · 2025
    Cross-sectional study7,433 participantsAnti-Aging forSelenium
  21. Minerals and Sarcopenia; The Role of Calcium, Iron, Magnesium, Phosphorus, Potassium, Selenium, Sodium, and Zinc on Muscle Mass, Muscle Strength, and Physical Performance in Older Adults: A Systematic Review.
    van Dronkelaar C; van Velzen A; Abdelrazek M; van der Steen A; Weijs PJM; Tieland M · Journal of the American Medical Directors Association · 2019
    Systematic review10 studies pooledAnti-Aging forSelenium
  22. Non-linear association between serum levels of vitamins A and B12 and accelerated epigenetic aging.
    Ma Z; An M; Gong W; Chen X; Liang M; Zhang J; Du X; Lu F; He Q; Wang M; Zhong J; Sun C · Frontiers in nutrition · 2025
    Cross-sectional study2,530 participantsAnti-Aging forVitamin B12
  23. Gender-specific impact of personal health parameters on individual brain aging in cognitively unimpaired elderly subjects.
    Franke K; Ristow M; Gaser C; Alzheimer's Disease Neuroimaging Initiative · Frontiers in aging neuroscience · 2014
    Cross-sectional study228 participantsAnti-Aging forVitamin B12
  24. Homocysteine and the risk of nursing home admission and mortality in older persons.
    Swart KM; van Schoor NM; Blom HJ; Smulders YM; Lips P · European journal of clinical nutrition · 2012
    Cohort study1,117 participantsAnti-Aging forVitamin B12
  25. Dynamics and interactions of cobalamin and folate status during advanced aging - a longitudinal study in a community-dwelling cohort with multiple follow-ups.
    Jungert A; Zenke-Philippi C; Neuhäuser-Berthold M · Nutrition journal · 2021
    Cohort study332 participantsAnti-Aging forVitamin B12
  26. Association between serum vitamin B12 and risk of all-cause mortality in elderly adults: a prospective cohort study.
    Xu K; Liu X; Liu J; Zhang Y; Ding X; Li L; Sun J · BMC geriatrics · 2021
    Cohort study2,086 participantsAnti-Aging forVitamin B12
  27. Study on the Multiple Efficacies of Vitamin C Serum in Anti-Glycation, Anti-Carbonylation, Antioxidation, and Anti-Inflammation of Human Skin Based on In Vivo Tests.
    Zi Y; Liu J; Liu Q; Pan Y; Jiang X · Journal of cosmetic dermatology · 2026
    Randomized trial66 participantsAnti-Aging forVitamin C
  28. Evaluation of the anti-wrinkle effect of a lipophilic pro-vitamin C derivative, tetra-isopalmitoyl ascorbic acid.
    Yokota M; Yahagi S · Journal of cosmetic dermatology · 2022
    Randomized trial69 participantsAnti-Aging forVitamin C
  29. The role of vitamin C in pushing back the boundaries of skin aging: an ultrasonographic approach.
    Crisan D; Roman I; Crisan M; Scharffetter-Kochanek K; Badea R · Clinical, cosmetic and investigational dermatology · 2015
    Clinical trial60 participantsAnti-Aging forVitamin C
  30. In vivo evaluation of topical ascorbic acid application on skin aging by 50 MHz ultrasound.
    Vergilio MM; Aiello LM; Furlan AS; Caritá AC; Azevedo JR; Bolzinger MA; Chevalier Y; Leonardi GR · Journal of cosmetic dermatology · 2022
    Randomized trial25 participantsAnti-Aging forVitamin C
  31. Clinical Applications of Vitamin C in Dermatology: A Systematic Review.
    Boghosian T; Mendez H; Boghosian N; Sayegh M; Beer J; Tosti A · The Journal of clinical and aesthetic dermatology · 2026
    Systematic review44 studies pooledAnti-Aging forVitamin C
  32. Therapeutic efficacy of bromelain in impacted third molar surgery: a randomized controlled clinical study.
    Ordesi P; Pisoni L; Nannei P; Macchi M; Borloni R; Siervo S · Quintessence international (Berlin, Germany : 1985) · 2016
    Randomized trial80 participantsAnti-Inflammatory Support forBromelain
  33. Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical trials.
    Mendes ML; do Nascimento-Júnior EM; Reinheimer DM; Martins-Filho PR · Medicina oral, patologia oral y cirugia bucal · 2019
    Meta-analysis6 studies pooledAnti-Inflammatory Support forBromelain
  34. Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain.
    Müller S; März R; Schmolz M; Drewelow B; Eschmann K; Meiser P · Phytotherapy research : PTR · 2013
    Randomized trial12 participantsAnti-Inflammatory Support Immunity forBromelain
  35. An Evaluation of the Effects of Pineapple-Extract and Bromelain-Based Treatment after Mandibular Third Molar Surgery: A Randomized Three-Arm Clinical Study.
    Colletti A; Procchio C; Pisano M; Martelli A; Pellizzato M; Cravotto G · Nutrients · 2024
    Randomized trial42 participantsAnti-Inflammatory Support forBromelain
  36. Therapeutic uses of pineapple-extracted bromelain in surgical care - A review.
    Muhammad ZA; Ahmad T · JPMA. The Journal of the Pakistan Medical Association · 2019
    Narrative reviewAnti-Inflammatory Support forBromelain
  37. Selenium and the course of mild Graves' orbitopathy.
    Marcocci C; Kahaly GJ; Krassas GE; Bartalena L; Prummel M; Stahl M; Altea MA; Nardi M; Pitz S; Boboridis K; Sivelli P; von Arx G; Mourits MP; Baldeschi L; Bencivelli W; Wiersinga W; European Group on Graves' Orbitopathy · The New England journal of medicine · 2011
    Randomized trial159 participantsAnti-Inflammatory Support forSelenium
  38. Effects of selenium supplementation on glucose homeostasis, inflammation, and oxidative stress in gestational diabetes: Randomized, double-blind, placebo-controlled trial.
    Asemi Z; Jamilian M; Mesdaghinia E; Esmaillzadeh A · Nutrition (Burbank, Los Angeles County, Calif.) · 2016
    Randomized trial70 participantsAnti-Inflammatory Support Metabolism Boost forSelenium
  39. Selenium Supplementation Affects Insulin Resistance and Serum hs-CRP in Patients with Type 2 Diabetes and Coronary Heart Disease.
    Farrokhian A; Bahmani F; Taghizadeh M; Mirhashemi SM; Aarabi MH; Raygan F; Aghadavod E; Asemi Z · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2017
    Randomized trial60 participantsAnti-Inflammatory Support forSelenium
  40. The effects of selenium supplementation on cardiovascular risk factors in patients with metabolic diseases ‒ A systematic review and meta-analysis of randomized controlled trials.
    Qiu W; Huang N; Zhang K; Qiu H; Guo Z; Han F; Sun X; Hou N; Kan C · Nutricion hospitalaria · 2026
    Meta-analysis656 participants11 studies pooledAnti-Inflammatory Support forSelenium
  41. Effects of Selenium Supplementation on Metabolic Status in Patients Undergoing for Coronary Artery Bypass Grafting (CABG) Surgery: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Kamali A; Amirani E; Asemi Z · Biological trace element research · 2020
    Randomized trial33 participantsAnti-Inflammatory Support forSelenium
  42. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support Joint Health forVitamin C
  43. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  44. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  45. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  46. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  47. Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
    Zhou A; Hyppönen E · International journal of epidemiology · 2023
    Observational study294,970 participantsAnti-Inflammatory Support forVitamin D
  48. Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
    El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  49. Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
    Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  50. Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
    Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
    Cross-sectional study9,809 participantsAnti-Inflammatory Support forVitamin D
  51. Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
    Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
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    Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
    Randomized trial110 participantsAnti-Inflammatory Support forVitamin E
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    Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
    Meta-analysis495 participants12 studies pooledAnti-Inflammatory Support forVitamin E
  54. Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
    Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
    Meta-analysis46 studies pooledAnti-Inflammatory Support forVitamin E
  55. Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
    Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
    Meta-analysis8 studies pooledAnti-Inflammatory Support forVitamin E
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    Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
    Randomized trial71 participantsAnti-Inflammatory Support forVitamin E
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    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
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    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  59. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
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    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
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    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
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    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  63. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
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    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
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    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
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    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  67. The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
    Ju Y; Xiong W; Pang Y; Chen Z; Hou J; Zheng S; Li Z; Liu T; Xia H; Xia M; Zhong Y; Li J; Jiang X · Biological trace element research · 2026
    Scoping review18 studies pooledBone Health forCopper
  68. Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
    Chen M; Jia L; Gao R · Frontiers in nutrition · 2024
    Cohort study5,286 participantsBone Health forCopper
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    Hu M; Wang Z; Li C; Zheng Y; Hu J · Medicine · 2025
    Cross-sectional studyBone Health forCopper
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    Wei M; Wei J; Huang S · Journal of health, population, and nutrition · 2025
    Cross-sectional study11,520 participantsBone Health forCopper
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    Cui A; Yan J; Li H; Fan Z; Wei X; Wang H; Zhuang Y · PloS one · 2024
    Cross-sectional study6,965 participantsBone Health forCopper
  72. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  73. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  74. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
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    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  76. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  77. Risk of Environmental Chemicals on Bone Fractures Is Independent of Low Bone Mass in US Adults: Insights from 2017 to 2018 NHANES.
    Ling R; Ai Y; Chen C; Zhang J; Zou Z; Cheng S; Li C; Li X; Wang B · Metabolites · 2023
    Cross-sectional study2,640 participantsBone Health forManganese
  78. The Manganese-Bone Connection: Investigating the Role of Manganese in Bone Health.
    Taskozhina G; Batyrova G; Umarova G; Issanguzhina Z; Kereyeva N · Journal of clinical medicine · 2024
    Narrative reviewBone Health forManganese
  79. Associations of multiple metals with bone mineral density: A population-based study in US adults.
    Wei MH; Cui Y; Zhou HL; Song WJ; Di DS; Zhang RY; Huang Q; Liu JA; Wang Q · Chemosphere · 2021
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    Li H; Li G; Yi M; Zhou J; Deng Y; Huang Y; He S; Meng X; Liu L · Frontiers in public health · 2024
    Cross-sectional study31 participantsBone Health forManganese
  81. Relationship between blood manganese and bone mineral density and bone mineral content in adults: A population-based cross-sectional study.
    Wang C; Zhu Y; Long H; Ou M; Zhao S · PloS one · 2022
    Cross-sectional study9,732 participantsBone Health forManganese
  82. Can Dietary Intake of Vitamin C-Oriented Foods Reduce the Risk of Osteoporosis, Fracture, and BMD Loss? Systematic Review With Meta-Analyses of Recent Studies.
    Zeng LF; Luo MH; Liang GH; Yang WY; Xiao X; Wei X; Yu J; Guo D; Chen HY; Pan JK; Huang HT; Liu Q; Guan ZT; Han YH; Zhao D; Zhao JL; Hou SR; Wu M; Lin JT; Li JH; Liang WX; Ou AH; Wang Q; Li ZP; Liu J · Frontiers in endocrinology · 2020
    Meta-analysis19,484 participants17 studies pooledBone Health forVitamin C
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    Sun Y; Liu C; Bo Y; You J; Zhu Y; Duan D; Cui H; Lu Q · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
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    Melhus H; Michaëlsson K; Holmberg L; Wolk A; Ljunghall S · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1999
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    Torbergsen AC; Watne LO; Wyller TB; Frihagen F; Strømsøe K; Bøhmer T; Mowe M · Clinical nutrition (Edinburgh, Scotland) · 2018
    Case-control study189 participantsBone Health forVitamin C
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    Kim YA; Kim KM; Lim S; Choi SH; Moon JH; Kim JH; Kim SW; Jang HC; Shin CS · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Cross-sectional study1,196 participantsBone Health forVitamin C
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    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
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    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
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    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
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  90. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  91. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
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  92. Increased incidence of fractures in middle-aged and elderly men with low intakes of phosphorus and zinc.
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  93. Zinc Supplementation Increases Procollagen Type 1 Amino-Terminal Propeptide in Premenarcheal Girls: A Randomized Controlled Trial.
    Berger PK; Pollock NK; Laing EM; Chertin V; Bernard PJ; Grider A; Shapses SA; Ding KH; Isales CM; Lewis RD · The Journal of nutrition · 2016
    Randomized trial147 participantsBone Health forZinc
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    Merialdi M; Caulfield LE; Zavaleta N; Figueroa A; Costigan KA; Dominici F; Dipietro JA · The American journal of clinical nutrition · 2004
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  95. The effects of zinc supplementation on serum zinc, alkaline phosphatase activity and fracture healing of bones.
    Sadighi A; Roshan MM; Moradi A; Ostadrahimi A · Saudi medical journal · 2009
    Randomized trial60 participantsBone Health forZinc
  96. Is Zinc an Important Trace Element on Bone-Related Diseases and Complications? A Meta-analysis and Systematic Review from Serum Level, Dietary Intake, and Supplementation Aspects.
    Ceylan MN; Akdas S; Yazihan N · Biological trace element research · 2021
    Meta-analysis40 studies pooledBone Health forZinc
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    Inoue T; Yoshida K; Sasaki E; Aizawa K; Kamioka H · Journal of food science · 2021
    Meta-analysis854 participants11 studies pooledCardiovascular Support forLycopene
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    Yoshida K; Nakazawa Y; Takahashi S; Suzuki S · Food & function · 2025
    Randomized trial75 participantsCardiovascular Support forLycopene
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    Cheng HM; Koutsidis G; Lodge JK; Ashor A; Siervo M; Lara J · Atherosclerosis · 2017
    Meta-analysis21 studies pooledCardiovascular Support forLycopene
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    Cheng HM; Koutsidis G; Lodge JK; Ashor AW; Siervo M; Lara J · Critical reviews in food science and nutrition · 2019
    Meta-analysis25 studies pooledCardiovascular Support forLycopene
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    Song B; Liu K; Gao Y; Zhao L; Fang H; Li Y; Pei L; Xu Y · Molecular nutrition & food research · 2018
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    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
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    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  104. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
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  106. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
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    Bazyar H; Moradi L; Zaman F; Zare Javid A · Phytotherapy research : PTR · 2023
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    Bazyar H; Zare Javid A; Ahangarpour A; Zaman F; Hosseini SA; Zohoori V; Aghamohammadi V; Yazdanfar S; Ghasemi Deh Cheshmeh M · Frontiers in nutrition · 2023
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    Young GL; Jewell D · The Cochrane database of systematic reviews · 2000
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    Randomized trial60 participantsCardiovascular Support forRutin
  111. Vitamin B12 Status and Cardiovascular Risk: Novel Insights from NMR-Based Lipoprotein Profiling in 20,665 Adults.
    Eken Y; Tekin N; Şahin F; Tay İ; Yıldırım Saral N; Serteser M; Baykal AT · Journal of clinical medicine · 2026
    Cross-sectional study20,665 participantsCardiovascular Support Heart Health forVitamin B12
  112. Pregnancy Metal Mixtures and Blood Pressure and Hypertension in Mid-Life: A Prospective U.S. Cohort Study.
    Zhang M; Aris IM; Cardenas A; Rifas-Shiman SL; Lin PD; Ngo LH; Oken E; Hivert MF; Juraschek SP · Hypertension (Dallas, Tex. : 1979) · 2025
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  113. Vitamin B12 Deficiency, Hyperhomocysteinemia, and Diabetes as Metabolic Determinants of Cardiovascular Risk in Mexican Women.
    Ramirez-Villalobos MD; Monterrubio-Flores E; Marquez-Murillo M; Alcalde-Rabanal J; Shamah-Levy T; Perichart-Perera O; Macias-Morales N; Campos-Nonato I · Nutrients · 2025
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    Wang C; Liu D; Tang M; Liu J; Ma Y · Journal of clinical biochemistry and nutrition · 2026
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    Datt V; Wadhhwa R; Sharma V; Virmani S; Minhas HS; Malik S · Journal of cardiac surgery · 2021
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    De Jesus Moreno Moreno M · Clinical therapeutics · 2003
    Randomized trial261 participantsCognitive Support forCholine
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    Niu YY; Yan HY; Zhong JF; Diao ZQ; Li J; Li CP; Chen LH; Huang WQ; Xu M; Xu ZT; Liang XF; Li ZH; Liu D · The American journal of clinical nutrition · 2025
    Cohort study125,594 participantsCognitive Support forCholine
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    Boeke CE; Gillman MW; Hughes MD; Rifas-Shiman SL; Villamor E; Oken E · American journal of epidemiology · 2013
    Cohort study895 participantsCognitive Support forCholine
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    Sohn M; Park YH; Lim S · Diabetes, obesity & metabolism · 2025
    Randomized trial36 participantsCognitive Support forCholine
  120. Maternal choline supplementation mitigates alcohol exposure effects on neonatal brain volumes.
    Warton FL; Molteno CD; Warton CMR; Wintermark P; Lindinger NM; Dodge NC; Zöllei L; van der Kouwe AJW; Carter RC; Jacobson JL; Jacobson SW; Meintjes EM · Alcoholism, clinical and experimental research · 2022
    Randomized trial52 participantsCognitive Support forCholine
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    Doyle LW; Crowther CA; Middleton P; Marret S; Rouse D · The Cochrane database of systematic reviews · 2009
    Meta-analysis6,145 participants5 studies pooledCognitive Support forMagnesium
  122. Effects of magnesium valproate adjuvant therapy on patients with dementia: A systematic review and meta-analysis.
    Zhang C; Sun L; Sun H · Medicine · 2022
    Meta-analysis1,899 participants22 studies pooledCognitive Support forMagnesium
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    Noor NJ; Syamsuddin S; Liaury K; Tawali S; Idris I; Azis I; Lisal ST · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan · 2026
    Randomized trial40 participantsCognitive Support forMagnesium
  124. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsCognitive Support forMagnesium
  125. Could intraoperative magnesium sulphate protect against postoperative cognitive dysfunction?
    Hassan WF; Tawfik MH; Nabil TM; Abd Elkareem RM · Minerva anestesiologica · 2021
    Randomized trial80 participantsCognitive Support forMagnesium
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    EFSA Panel on Nutrition, Novel Foods and Food allergens (NDA); Turck D; Bohn T; Castenmiller J; De Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Naska A; Pentieva K; Thies F; Tsabouri S; Vinceti M; Bresson JL; Fiolet T; Siani A · EFSA journal. European Food Safety Authority · 2024
    Guideline / consensusDetoxification forCholine
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    Mazidi M; Katsiki N; Mikhailidis DP; Banach M · Journal of the American College of Nutrition · 2020
    Cross-sectional study20,643 participantsDetoxification forCholine
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    Hilberath J; Shunova A; Heister L; Poets CF; Bernhard W · Nutrients · 2026
    Observational study80 participantsDetoxification forCholine
  129. Choline Supplementation in Cystic Fibrosis-The Metabolic and Clinical Impact.
    Bernhard W; Lange R; Graepler-Mainka U; Engel C; Machann J; Hund V; Shunova A; Hector A; Riethmüller J · Nutrients · 2019
    Single-arm trial10 participantsDetoxification forCholine
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    Hawesa H; Alghamdi R; Allam H; Alfaifi B; Alrabiah N; Alghumaiz M; Shanawani M; Alshegri H; Hassan MG · Current medical imaging · 2026
    Cohort study88 participantsDetoxification forCholine
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    Harada S; Takebayashi T; Kurihara A; Akiyama M; Suzuki A; Hatakeyama Y; Sugiyama D; Kuwabara K; Takeuchi A; Okamura T; Nishiwaki Y; Tanaka T; Hirayama A; Sugimoto M; Soga T; Tomita M · Environmental health and preventive medicine · 2016
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    Gullestad L; Dolva LO; Søyland E; Manger AT; Falch D; Kjekshus J · Alcoholism, clinical and experimental research · 1992
    Randomized trial49 participantsDetoxification forMagnesium
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    Farshidi H; Sobhani AR; Eslami M; Azarkish F; Eftekhar E; Keshavarz M; Soltani N · Journal of cardiovascular pharmacology · 2021
    Randomized trialDetoxification forMagnesium
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    Asemi Z; Aarabi MH; Hajijafari M; Alizadeh SA; Razzaghi R; Mazoochi M; Esmaillzadeh A · International journal of preventive medicine · 2020
    Randomized trialDetoxification forMagnesium
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    Daus AT; Freeman WM; Wilson J; Aponte C · The International journal of the addictions · 1985
    Observational study781 participantsDetoxification forMagnesium
  136. Ionized hypomagnesemia in patients undergoing orthotopic liver transplantation: a complication of citrate intoxication.
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    Single-arm trialDetoxification forMagnesium
  137. Human molybdenum exposure risk in industrial regions of China: New critical effect indicators and reference dose.
    Kuang HX; Li MY; Zeng XW; Chen D; Zhou Y; Zheng T; Xiang MD; Wu QZ; Chen XC; Dong GH; Yu YJ · Ecotoxicology and environmental safety · 2024
    Cross-sectional study2,267 participantsDetoxification forMolybdenum
  138. Supplementation with selenium can influence nausea, fatigue, physical, renal, and liver function of children and adolescents with cancer.
    Vieira ML; Fonseca FL; Costa LG; Beltrame RL; Chaves CM; Cartum J; Alves SI; Azzalis LA; Junqueira VB; Pereria EC; Rocha KC · Journal of medicinal food · 2015
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  139. [Selenium and oxidative stress in cancer patients].
    Gorozhanskaia ÉG; Sviridova SP; Dobrovol'skaia MM; Zybrikhina GN; Kashnia ShR · Biomeditsinskaia khimiia · 2014
    Single-arm trial40 participantsDetoxification forSelenium
  140. Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study.
    Li C; Peng X; Zheng J; Shi K; Qin L; Yang Q; Wang Z; Liu Y; Huang L · Biological trace element research · 2024
    Other40 participantsDetoxification forSelenium
  141. Heavy metals and metalloids exposure and liver function in Chinese adults - A nationally representative cross-sectional study.
    Wang S; Lyu Y; Ji S; Liu N; Wu B; Zhao F; Li Z; Qu Y; Zhu Y; Xie L; Li Y; Zhang Z; Song H; Hu X; Qiu Y; Zheng X; Zhang W; Yang Y; Li F; Cai J; Zhu Y; Cao Z; Tan F; Shi X · Environmental research · 2024
    Cross-sectional study9,445 participantsDetoxification forSelenium
  142. Selenium-Biofortified Strawberries Improve Glucose Homeostasis and Hepatic Function: A 30-Day Randomized Controlled Trial in Healthy Adults.
    Vasto S; Di Rosa L; Ferrantelli V; Fiore AS; Giordano CP; Cannizzaro A; Sabatino L; Macaluso A; Caldarella R; Caldara GF; Baldassano S · Nutrients · 2026
    Randomized trial35 participantsDetoxification forSelenium
  143. Vitamin C supplementation ameliorates liver function profile and antiviral treatment response in Hepatitis C patients.
    Nayila I; Javed MS; Khan MA; Hussain G; Raza Naqvi SA; Ali S; Jabeen Z; Shahnawaz S; Akram R; Iman T; Hassan Dogar MZ; Malik SA · Pakistan journal of pharmaceutical sciences · 2022
    Non-randomized trial200 participantsDetoxification forVitamin C
  144. Effect of ascorbic acid-rich diet on in vivo-induced oxidative stress.
    Alleva R; Di Donato F; Strafella E; Staffolani S; Nocchi L; Borghi B; Pignotti E; Santarelli L; Tomasetti M · The British journal of nutrition · 2012
    Non-randomized trial46 participantsDetoxification forVitamin C
  145. Dietary Vitamin C Intake Is Associated With Improved Liver Function and Glucose Metabolism in Chinese Adults.
    Luo X; Zhang W; He Z; Yang H; Gao J; Wu P; Ma ZF · Frontiers in nutrition · 2022
    Observational study8,307 participantsDetoxification forVitamin C
  146. Plasma ascorbate deficiency is associated with impaired reduction of sulfamethoxazole-nitroso in HIV infection.
    Trepanier LA; Yoder AR; Bajad S; Beckwith MD; Bellehumeur JL; Graziano FM · Journal of acquired immune deficiency syndromes (1999) · 2005
    Observational studyDetoxification forVitamin C
  147. Roles of endogenous ascorbate and glutathione in the cellular reduction and cytotoxicity of sulfamethoxazole-nitroso.
    Lavergne SN; Kurian JR; Bajad SU; Maki JE; Yoder AR; Guzinski MV; Graziano FM; Trepanier LA · Toxicology · 2006
    Clinical trial53 participantsDetoxification forVitamin C
  148. The role of enzyme supplementation in digestive disorders.
    Roxas M · Alternative medicine review : a journal of clinical therapeutic · 2009
    Narrative reviewDigestive Health forBromelain
  149. Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study.
    Delgarm P; Mokhtare M; Ebrahimi Daryani N; Abolghasemi J; Rahideh ST · Scientific reports · 2025
    Randomized trial70 participantsDigestive Health forBromelain
  150. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  151. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  152. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  153. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  154. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  155. The incidence and clinical implications of hypersensitivity to papain in an allergic population, confirmed by blinded oral challenge.
    Mansfield LE; Ting S; Haverly RW; Yoo TJ · Annals of allergy · 1985
    Clinical trial500 participantsDigestive Health forPapain
  156. Papaya preparation (Caricol®) in digestive disorders
    Muss C, Mosgoeller W, Endler T · Neuro Endocrinology Letters · 2013
    Randomized trial76 participantsDigestive Health forPapain
  157. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsGeneral Health forFolate
  158. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsGeneral Health forFolate
  159. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsGeneral Health forFolate
  160. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewGeneral Health forFolate
  161. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledGeneral Health forFolate
  162. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  163. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  164. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  165. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  166. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  167. Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
    Randomized trial40 participantsGeneral Health forVitamin B12
  168. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
    Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
    Randomized trial90 participantsGeneral Health forVitamin B12
  169. A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
    Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
    Randomized trial98 participantsGeneral Health forVitamin B12
  170. Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
    Randomized trial204 participantsGeneral Health forVitamin B12
  171. The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
    Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
    Clinical trial50 participantsGeneral Health forVitamin B12
  172. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsHair Health Nail Health forBiotin
  173. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsHair Health forBiotin
  174. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  175. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
  176. Menkes disease and response to copper histidine: An Indian case series.
    Yoganathan S; Sudhakar SV; Arunachal G; Thomas M; Subramanian A; George R; Danda S · Annals of Indian Academy of Neurology · 2022
    Case series4 participantsHair Health forCopper
  177. Trace element levels in alopecia areata.
    Bhat YJ; Manzoor S; Khan AR; Qayoom S · Indian journal of dermatology, venereology and leprology · 2009
    Case-control study100 participantsHair Health forCopper
  178. UV damage to hair and the effect of antioxidants and metal chelators.
    Millington KR; Marsh JM · International journal of cosmetic science · 2021
    In vitro / ex vivo studyHair Health forCopper
  179. Preserving fibre health: reducing oxidative stress throughout the life of the hair fibre.
    Marsh JM; Davis MG; Lucas RL; Reilman R; Styczynski PB; Li C; Mamak M; McComb DW; Williams RE; Godfrey S; Navqi KR; Chechik V · International journal of cosmetic science · 2016
    In vitro / ex vivo studyHair Health forCopper
  180. [Evaluation of the role of dietary intake in the occurrence of alopecia].
    El Fékih N; Kamoun H; Fazaa B; El Ati J; Zouari B; Kamoun MR; Gaigi S · Revue medicale de Liege · 2010
    Case-control study272 participantsHair Health forIodine
  181. Beyond Efficacy: 0.6% Selenium Disulfide Shampoo Matches 2% Ketoconazole for Seborrheic Dermatitis with Superior Cosmesis.
    Farris PK; Barbosa V; Houshman EB; Kovylkina N · Journal of drugs in dermatology : JDD · 2026
    Randomized trial87 participantsHair Health forSelenium
  182. Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis.
    Turcu G; Artenie C; Nowicka D; Arenbergerová M; Lazaridou E; Khobzei K; Ataseven A; Part M; Leclerc-Mercier S · European journal of dermatology : EJD · 2023
    Observational study1,407 participantsHair Health forSelenium
  183. A Comparative Randomized Clinical Study Assessing the Efficacy of a 1% Selenium Disulfide-Based Shampoo versus 2% Ketoconazole Shampoo in Subjects with Moderate to Severe Scalp Seborrheic Dermatitis.
    Barbosa V; Melo DF; Vañó-Galván S; Lutchmanen-Kolanthan V; Sant'Anna B; Leclerc-Mercier S; Reygagne P · Skin appendage disorders · 2025
    Randomized trial64 participantsHair Health forSelenium
  184. Changes of serum trace elements level in patients with alopecia areata: A meta-analysis.
    Jin W; Zheng H; Shan B; Wu Y · The Journal of dermatology · 2018
    Meta-analysis764 participantsHair Health forSelenium
  185. Scientific opinion on the tolerable upper intake level for selenium.
    EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA); Turck D; Bohn T; Castenmiller J; de Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Peláez C; Pentieva K; Siani A; Thies F; Tsabouri S; Vinceti M; Aggett P; Crous Bou M; Cubadda F; Ciccolallo L; de Sesmaisons Lecarré A; Fabiani L; Titz A; Naska A · EFSA journal. European Food Safety Authority · 2023
    Systematic reviewHair Health forSelenium
  186. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  187. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
    Methods validation study201,019 participantsHair Health forVitamin C
  188. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  189. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
    Methods validation studyHair Health forVitamin C
  190. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
    Case reportHair Health forVitamin C
  191. Increased prevalence of vitamin D deficiency in patients with alopecia areata: a systematic review and meta-analysis.
    Lee S; Kim BJ; Lee CH; Lee WS · Journal of the European Academy of Dermatology and Venereology : JEADV · 2018
    Meta-analysis2,039 participants14 studies pooledHair Health forVitamin D
  192. Intralesional vitamin D3 in treatment of alopecia areata: A randomized controlled clinical trial.
    Rashad AF; Elgamal E; Fouda I · Journal of cosmetic dermatology · 2022
    Randomized trial60 participantsHair Health forVitamin D
  193. Vitamin D and its Analogs in Treatment of Mild to Moderate Alopecia Areata: Systematic Review and Meta-Analysis.
    Alsaati AA; Kaliyadan F; Alsaadoun D; Alzakry LM; Alzabadin RA; Hakami TH; Rubaian NFB · Indian dermatology online journal · 2025
    Meta-analysisHair Health forVitamin D
  194. Topical calcipotriol vs narrowband ultraviolet B in treatment of alopecia areata: a randomized-controlled trial.
    El Taieb MA; Hegazy EM; Ibrahim HM; Osman AB; Abualhamd M · Archives of dermatological research · 2020
    Randomized trial60 participantsHair Health forVitamin D
  195. Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis.
    Chen Y; Dong X; Wang Y; Li Y; Xiong L; Li L · Journal of cosmetic dermatology · 2024
    Meta-analysis10,670 participants23 studies pooledHair Health forVitamin D
  196. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  197. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  198. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  199. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  200. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  201. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  202. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  203. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  204. Vitamin B12 deficiency is associated with cardiovascular autonomic neuropathy in patients with type 2 diabetes.
    Hansen CS; Jensen JS; Ridderstråle M; Vistisen D; Jørgensen ME; Fleischer J · Journal of diabetes and its complications · 2018
    Cross-sectional study469 participantsHeart Health forVitamin B12
  205. Vitamin B12 and folate status in early pregnancy and cardiometabolic risk factors in the offspring at age 5-6 years: findings from the ABCD multi-ethnic birth cohort.
    Krikke GG; Grooten IJ; Vrijkotte TG; van Eijsden M; Roseboom TJ; Painter RC · BJOG : an international journal of obstetrics and gynaecology · 2016
    Cohort study1,950 participantsHeart Health forVitamin B12
  206. Orthostatic tolerance in older patients with vitamin B12 deficiency before and after vitamin B12 replacement.
    Moore A; Ryan J; Watts M; Pillay I; Clinch D; Lyons D · Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2004
    Non-randomized trial16 participantsHeart Health forVitamin B12
  207. The impact of folic acid/VB12 deficiency on essential hypertension in children and adolescents: from a nested case-control and a cohort study.
    Liang X; Huang D; Bi Y; He Y; Mao T; Liu Q; Hu G; Tong J; Chen L; Wang Y; An X; Jiang X; Tahir MF · Journal of human hypertension · 2024
    Observational study596 participantsHeart Health forVitamin B12
  208. Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies.
    Jayedi A; Zargar MS · Critical reviews in food science and nutrition · 2020
    Meta-analysis369,746 participants11 studies pooledHeart Health forVitamin B6
  209. Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women.
    Rimm EB; Willett WC; Hu FB; Sampson L; Colditz GA; Manson JE; Hennekens C; Stampfer MJ · JAMA · 1998
    Cohort study80,082 participantsHeart Health forVitamin B6
  210. Intake of folate, vitamin B6 and vitamin B12 and the risk of CHD: the Japan Public Health Center-Based Prospective Study Cohort I.
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    Cohort study40,803 participantsHeart Health forVitamin B6
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    Miao Y; Guo Y; Chen Y; Lin Y; Lu Y; Guo Q · Nutrition reviews · 2024
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  212. Folate and vitamin B(6) intake and risk of acute myocardial infarction in Italy.
    Tavani A; Pelucchi C; Parpinel M; Negri E; La Vecchia C · European journal of clinical nutrition · 2005
    Case-control study985 participantsHeart Health forVitamin B6
  213. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  214. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  215. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  216. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  217. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium
  218. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  219. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  220. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  221. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  222. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  223. Essentiality of boron for healthy bones and joints.
    Newnham RE · Environmental health perspectives · 1995
    Randomized trial20 participantsJoint Health forBoron
  224. Short-term efficacy of calcium fructoborate on subjects with knee discomfort: a comparative, double-blind, placebo-controlled clinical study
    Zbigniew Pietrzkowski, Michael J Phelan, Robert Keller, Cynthia Shu, Ruby Argumedo, Tania Reyes-Izquierdo · Clinical Interventions in Aging · 2014
    Randomized trial60 participantsJoint Health forBoron
  225. A double-blind, placebo-controlled pilot study to evaluate the effect of calcium fructoborate on systemic inflammation and dyslipidemia markers for middle-aged people with primary osteoarthritis
    Romulus Scorei, Paul Mitrut, Iulian Petrisor, Iulia Scorei · Biological Trace Element Research · 2011
    Randomized trial60 participantsJoint Health forBoron
  226. Bromelain as a Treatment for Osteoarthritis: a Review of Clinical Studies.
    Brien S; Lewith G; Walker A; Hicks SM; Middleton D · Evidence-based complementary and alternative medicine : eCAM · 2024
    Narrative reviewJoint Health forBromelain
  227. Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis.
    Kasemsuk T; Saengpetch N; Sibmooh N; Unchern S · Clinical rheumatology · 2017
    Randomized trial40 participantsJoint Health forBromelain
  228. Oral enzyme combination therapy reduces systemic inflammation, urinary CTXII and pain in knee osteoarthritis: a proof-of-mechanism, randomised, crossover, double-blind, placebo-controlled trial.
    Henrotin Y; Pap T; Lieten S; Badot V; Dubuc JE; Urbin-Choffray D; von Eynatten M; Johansen OE; Rau S; Brabants K · RMD open · 2025
    Randomized trial45 participantsJoint Health forBromelain
  229. Efficacy, tolerability, and safety of an oral enzyme combination vs diclofenac in osteoarthritis of the knee: results of an individual patient-level pooled reanalysis of data from six randomized controlled trials
    Ueberall MA, Mueller-Schwefe GH, Wigand R, Essner U · Journal of Pain Research · 2016
    Meta-analysis697 participants6 studies pooledJoint Health forBromelain
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    Bolten WW, Glade MJ, Raum S, Ritz BW · Arthritis · 2015
    Randomized trial150 participantsJoint Health forBromelain
  231. Analgesic effect and safety of single-dose intra-articular magnesium after arthroscopic surgery: a systematic review and meta-analysis.
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    Meta-analysis16 studies pooledJoint Health forMagnesium
  232. Dose-response relationship between lower serum magnesium level and higher prevalence of knee chondrocalcinosis.
    Zeng C; Wei J; Terkeltaub R; Yang T; Choi HK; Wang YL; Xie DX; Hunter DJ; Zhang Y; Li H; Cui Y; Li LJ; Lei GH · Arthritis research & therapy · 2018
    Cross-sectional study13,947 participantsJoint Health forMagnesium
  233. Low magnesium intake is associated with increased knee pain in subjects with radiographic knee osteoarthritis: data from the Osteoarthritis Initiative.
    Shmagel A; Onizuka N; Langsetmo L; Vo T; Foley R; Ensrud K; Valen P · Osteoarthritis and cartilage · 2019
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  235. Associations of Dietary Macroelements with Knee Joint Structures, Symptoms, Quality of Life, and Comorbid Conditions in People with Symptomatic Knee Osteoarthritis.
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  236. Identification for heavy metals exposure on osteoarthritis among aging people and Machine learning for prediction: A study based on NHANES 2011-2020.
    Xia F; Li Q; Luo X; Wu J · Frontiers in public health · 2022
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  237. Efficacy of a combination of FCHG49 glucosamine hydrochloride, TRH122 low molecular weight sodium chondroitin sulfate and manganese ascorbate in the management of knee osteoarthritis
    A. Das Jr., T. A. Hammad · Osteoarthritis and Cartilage · 2000
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  238. Glucosamine, chondroitin, and manganese ascorbate for degenerative joint disease of the knee or low back: a randomized, double-blind, placebo-controlled pilot study
    C. T. Leffler, A. F. Philippi, S. G. Leffler, J. C. Mosure, P. D. Kim · Military Medicine · 1999
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  239. Efficiency of proteolytic enzymes in treating lumbar spine osteoarthritis (low back pain) patients and its effects on liver and kidney enzymes
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  240. Silicon Interpositional Arthroplasty for Temporo-mandibular Joint Ankylosis.
    Agarwal P; Singh MP; Tiwari S; Sharma D · Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
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  241. A 12-week randomized, double-blind, placebo-controlled multicenter study of choline-stabilized orthosilicic acid in patients with symptomatic knee osteoarthritis.
    Geusens P; Pavelka K; Rovensky J; Vanhoof J; Demeester N; Calomme M; Vanden Berghe D · BMC musculoskeletal disorders · 2017
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  242. Comparison of tendon suspension-interposition and silicon spacers in the treatment of degenerative osteoarthritis of the base of the thumb.
    Lehmann O; Herren DB; Simmen BR · Annales de chirurgie de la main et du membre superieur : organe officiel des societes de chirurgie de la main = Annals of hand and upper limb surgery · 2000
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  243. Ultrasonographic assessment of the quadriceps muscle and femoral cartilage in transtibial amputees using different prostheses.
    Şahin Onat Ş; Malas FÜ; Öztürk GT; Akkaya N; Kara M; Özçakar L · Prosthetics and orthotics international · 2017
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  244. Effects of Multiple Intravenous Doses of Perioperative Vitamin C on Pain Management Following Total Hip Arthroplasty.
    Han G; Ye Y; Kang P · Drug design, development and therapy · 2025
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  246. Anti-Inflammatory Effect of Vitamin C during the Postoperative Period in Patients Subjected to Total Knee Arthroplasty: A Randomized Controlled Trial.
    Ramón R; Holguín E; Chiriboga JD; Rubio N; Ballesteros C; Ezechieli M · Journal of personalized medicine · 2023
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  247. Musculoskeletal manifestations of scurvy.
    Fain O · Joint bone spine · 2005
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  248. The influence of zinc and iron intake on osteoarthritis patients' subchondral sclerosis progression: A prospective observational study using data from the osteoarthritis Initiative.
    Zheng Z; Luo H; Sun C; Xue Q · Heliyon · 2023
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    Simkin PA · Lancet (London, England) · 1976
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  250. Psoriatic arthritis treated with oral zinc sulphate.
    Clemmensen OJ; Siggaard-Andersen J; Worm AM; Stahl D; Frost F; Bloch I · The British journal of dermatology · 1981
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  252. The Daily Intake Levels of Copper, Selenium, and Zinc Are Associated with Osteoarthritis but Not with Rheumatoid Arthritis in a Cross-sectional Study.
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  254. Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Jamilian M; Asemi Z · Annals of nutrition & metabolism · 2016
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  255. A Comprehensive insight into the effect of chromium supplementation on oxidative stress indices in diabetes mellitus: A systematic review.
    Kooshki F; Tutunchi H; Vajdi M; Karimi A; Niazkar HR; Shoorei H; Pourghassem Gargari B · Clinical and experimental pharmacology & physiology · 2024
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    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
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  257. [Chromium supplementation in patients with type 2 diabetes and high risk of type 2 diabetes: a meta-analysis of randomized controlled trials].
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  258. Iodine Supplementation Decreases Hypercholesterolemia in Iodine-Deficient, Overweight Women: A Randomized Controlled Trial.
    Herter-Aeberli I; Cherkaoui M; El Ansari N; Rohner R; Stinca S; Chabaa L; von Eckardstein A; Aboussad A; Zimmermann MB · The Journal of nutrition · 2015
    Randomized trial163 participantsMetabolism Boost forIodine
  259. Effect of oral iodized oil on thyroid size and thyroid hormone metabolism in children with concurrent selenium and iodine deficiency.
    Zimmermann MB; Adou P; Torresani T; Zeder C; Hurrell RF · European journal of clinical nutrition · 2000
    Single-arm trial51 participantsMetabolism Boost forIodine
  260. Serum Iodine Concentration as a Biomarker for Individual Iodine Nutrition and Thyroid Function in Pregnant Women: A Cross-Sectional Study in Hubei Province.
    Xu M; Dai X; Wang Z; Guo C; Zhang B; Guo H · Public health nutrition · 2026
    Cross-sectional study1,197 participantsMetabolism Boost forIodine
  261. Iron status influences the efficacy of iodine prophylaxis in goitrous children in Côte d'Ivoire.
    Zimmermann MB · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2002
    OtherMetabolism Boost forIodine
  262. Persistence of goiter despite oral iodine supplementation in goitrous children with iron deficiency anemia in Côte d'Ivoire.
    Zimmermann M; Adou P; Torresani T; Zeder C; Hurrell R · The American journal of clinical nutrition · 2000
    Non-randomized trial109 participantsMetabolism Boost forIodine
  263. Association of magnesium consumption with type 2 diabetes and glucose metabolism: A systematic review and pooled study with trial sequential analysis.
    Zhao B; Deng H; Li B; Chen L; Zou F; Hu L; Wei Y; Zhang W · Diabetes/metabolism research and reviews · 2021
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    Tan X; Huang Y · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
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  265. Impact of oral magnesium supplementation on glycemic and cardiometabolic outcomes in prediabetic adults: a systematic review and meta-analysis.
    Basit A; Kumar S; Ahmed H; Babar R; Saeed SS; Siddiqui TA; Khan S; Saeed A; Khan M; Hanif H; Fasih A; Shabbir S; Kumar H; Kumar L; Raja A; Kumar S; Chander S · Journal of diabetes and metabolic disorders · 2026
    Meta-analysis384 participants5 studies pooledMetabolism Boost forMagnesium
  266. Oral magnesium supplementation improves insulin sensitivity and metabolic control in type 2 diabetic subjects: a randomized double-blind controlled trial.
    Rodríguez-Morán M; Guerrero-Romero F · Diabetes care · 2003
    Randomized trial63 participantsMetabolism Boost forMagnesium
  267. Magnesium Supplementation and the Effects on Wound Healing and Metabolic Status in Patients with Diabetic Foot Ulcer: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Razzaghi R; Pidar F; Momen-Heravi M; Bahmani F; Akbari H; Asemi Z · Biological trace element research · 2018
    Randomized trial70 participantsMetabolism Boost forMagnesium
  268. Metabolic response to selenium supplementation in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial.
    Jamilian M; Razavi M; Fakhrie Kashan Z; Ghandi Y; Bagherian T; Asemi Z · Clinical endocrinology · 2016
    Randomized trial70 participantsMetabolism Boost forSelenium
  269. The Effects of Selenium Supplementation on Gene Expression Related to Insulin and Lipid Metabolism, and Pregnancy Outcomes in Patients with Gestational Diabetes Mellitus: a Randomized, Double-Blind, Placebo-Controlled Trial.
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  270. Glycemic and lipid responses to selenium-enriched vs. zeaxanthin-enriched eggs in patients with type 2 diabetes: a 12-week randomized controlled trial.
    Niu X; Zhang Y; Liu Y; Zhu Y; Fang B; Hu C; Xu X; Wang R; Sang Y; Zhang Q; Guo J · Frontiers in nutrition · 2026
    Randomized trial58 participantsMetabolism Boost forSelenium
  271. The efficacy and safety of nutrient supplements in the treatment of mental disorders: a meta-review of meta-analyses of randomized controlled trials.
    Firth J; Teasdale SB; Allott K; Siskind D; Marx W; Cotter J; Veronese N; Schuch F; Smith L; Solmi M; Carvalho AF; Vancampfort D; Berk M; Stubbs B; Sarris J · World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025
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    Jin X; Cheng Z; Yu X; Tao Q; Huang R; Wang S · Journal of affective disorders · 2022
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    Borges-Vieira JG; Cardoso CKS · Nutritional neuroscience · 2023
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  276. Protective role of antioxidant supplementation for depression and anxiety: A meta-analysis of randomized clinical trials.
    Wang H; Jin M; Xie M; Yang Y; Xue F; Li W; Zhang M; Li Z; Li X; Jia N; Liu Y; Cui X; Hu G; Dong L; Wang G; Yu Q · Journal of affective disorders · 2023
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  277. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
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  278. Magnesium supplementation as an adjunct to fluoxetine therapy for depression.
    Walyddaini AS; Lisal ST; Ilhamuddin; Zainuddin AA; Tanra AJ; Widianingsih Y; Syamsuddin S · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan · 2026
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  279. The effects of magnesium supplementation on serum level of brain derived neurotrophic factor (BDNF) and depression status in patients with depression.
    Afsharfar M; Shahraki M; Shakiba M; Asbaghi O; Dashipour A · Clinical nutrition ESPEN · 2021
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  280. Dietary magnesium intake and risk of depression.
    Sun C; Wang R; Li Z; Zhang D · Journal of affective disorders · 2019
    Cross-sectional study17,730 participantsMood Support forMagnesium
  281. Subjective well-being in older adults: folate and vitamin B12 independently predict positive affect.
    Edney LC; Burns NR; Danthiir V · The British journal of nutrition · 2016
    Cohort study391 participantsMood Support forVitamin B12
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    Cruz-Rodríguez J; Canals-Sans J; Hernández-Martínez C; Arija V · Journal of reproductive and infant psychology · 2025
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    Soriano-Gonzalez R; Ramirez-Olea H; Gonzalez-Soltero R; Chavez-Santoscoy RA · Frontiers in nutrition · 2025
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    Wu Y; Li S; Wang W; Zhang D · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2023
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    Lipner SR; Scher RK · The Journal of dermatological treatment · 2018
    Narrative reviewNail Health forBiotin
  286. Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy.
    Colombo VE; Gerber F; Bronhofer M; Floersheim GL · Journal of the American Academy of Dermatology · 1991
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  287. Treatment of brittle nail with a hydroxypropyl chitosan-based lacquer, alone or in combination with oral biotin: A randomized, assessor-blinded trial.
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    Barel A; Calomme M; Timchenko A; De Paepe K; Demeester N; Rogiers V; Clarys P; Vanden Berghe D · Archives of dermatological research · 2006
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    Zaraa I; Richert B · Skin appendage disorders · 2026
    Narrative reviewNail Health forSilicon
  292. Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient.
    Dunleavy KA; Ungaro RC; Manning L; Gold S; Novak J; Colombel JF · Crohn's & colitis 360 · 2023
    Other20 participantsNail Health forVitamin C
  293. Noninferiority of Copper Dressings Than Negative Pressure Wound Therapy in Healing Diabetic Wounds: A Randomized Clinical Trial.
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  295. Radially Electrospun Fibrous Membrane Incorporated with Copper Peroxide Nanodots Capable of Self-Catalyzed Chemodynamic Therapy for Angiogenesis and Healing Acceleration of Diabetic Wounds.
    Huang Y; Qi L; Liu Z; Jiang Y; Wang J; Liu L; Li Y; Zhang L; Feng G · ACS applied materials & interfaces · 2023
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    Sahoo M; Banerjee T; Virkar S; Das S; Biswas S; Mitra D · Journal of materials chemistry. B · 2026
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    Melamed E; Rovitsky A; Roth T; Assa L; Borkow G · Medicina (Kaunas, Lithuania) · 2021
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    Aust O; Stahl W; Sies H; Tronnier H; Heinrich U · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2005
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    Kim J; Park MK; Li WQ; Qureshi AA; Cho E · JAMA dermatology · 2024
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  301. β-Carotene and other carotenoids in protection from sunlight.
    Stahl W; Sies H · The American journal of clinical nutrition · 2013
    Narrative reviewSkin Health forLycopene
  302. The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer.
    Hakozaki T; Minwalla L; Zhuang J; Chhoa M; Matsubara A; Miyamoto K; Greatens A; Hillebrand GG; Bissett DL; Boissy RE · The British journal of dermatology · 2002
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    Bissett DL; Oblong JE; Berge CA · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2005
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    Chiu PC; Chan CC; Lin HM; Chiu HC · Journal of cosmetic dermatology · 2008
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    Chen AC; Martin AJ; Choy B; Fernández-Peñas P; Dalziell RA; McKenzie CA; Scolyer RA; Dhillon HM; Vardy JL; Kricker A; St George G; Chinniah N; Halliday GM; Damian DL · The New England journal of medicine · 2015
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  307. Comparative clinical trial of bifonazole solution versus selenium sulphide shampoo in the treatment of pityriasis versicolor.
    Chu AC · Dermatologica · 1985
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  308. Selenium supplementation and secondary prevention of nonmelanoma skin cancer in a randomized trial.
    Duffield-Lillico AJ; Slate EH; Reid ME; Turnbull BW; Wilkins PA; Combs GF; Park HK; Gross EG; Graham GF; Stratton MS; Marshall JR; Clark LC; Nutritional Prevention of Cancer Study Group · Journal of the National Cancer Institute · 2003
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  309. Evidence-Based Nutritional Interventions in Wound Care.
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  310. A randomized, double-blind placebo-controlled trial evaluating the effects of vitamin E and selenium on arsenic-induced skin lesions in Bangladesh.
    Verret WJ; Chen Y; Ahmed A; Islam T; Parvez F; Kibriya MG; Graziano JH; Ahsan H · Journal of occupational and environmental medicine · 2006
    Randomized trial121 participantsSkin Health forSelenium
  311. The Whitening, Moisturizing, Anti-aging Activities, and Skincare Evaluation of Selenium-Enriched Mung Bean Fermentation Broth.
    Wei K; Guo C; Zhu J; Wei Y; Wu M; Huang X; Zhang M; Li J; Wang X; Wang Y; Wei X · Frontiers in nutrition · 2022
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  312. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
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  313. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
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  314. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
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    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
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    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  317. Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis.
    Javanbakht MH; Keshavarz SA; Djalali M; Siassi F; Eshraghian MR; Firooz A; Seirafi H; Ehsani AH; Chamari M; Mirshafiey A · The Journal of dermatological treatment · 2011
    Randomized trial45 participantsSkin Health forVitamin E
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  319. Effects of tocotrienol on aging skin: A systematic review.
    Ghazali NI; Mohd Rais RZ; Makpol S; Chin KY; Yap WN; Goon JA · Frontiers in pharmacology · 2022
    Systematic reviewSkin Health forVitamin E
  320. Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans.
    Stahl W; Heinrich U; Jungmann H; Sies H; Tronnier H · The American journal of clinical nutrition · 2000
    Randomized trialSkin Health forVitamin E
  321. Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
    Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
    Meta-analysis2,088 participants20 studies pooledSkin Health forZinc
  322. Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
    Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
    Cohort study23 participantsSkin Health forZinc
  323. Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
    Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
    Randomized trial30 participantsSkin Health forZinc
  324. A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
    Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
    Randomized trial90 participantsSkin Health forZinc
  325. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  326. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
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    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
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  337. Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
    Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
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    Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
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    Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
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    Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
    Other4,254 participantsTestosterone Support forVitamin D
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    Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
    Scoping reviewTestosterone Support forZinc
  344. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
    Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
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  347. The Associations of Plasma Carotenoids and Vitamins With Risk of Age-Related Macular Degeneration: Results From a Matched Case-Control Study in China and Meta-Analysis.
    Jiang H; Fan Y; Li J; Wang J; Kong L; Wang L; Li Z; Ma M; Shi X; Liu S; Shi J; Zhu H; Liu X; Ma L · Frontiers in nutrition · 2022
    Meta-analysis9 studies pooledVision Support forLycopene
  348. Serum carotenoids and risk of age-related macular degeneration in a chinese population sample.
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    Che S; Ma Y; Cao J · Frontiers in medicine · 2025
    Cross-sectional study1,478 participantsVision Support forLycopene
  351. Plasma antioxidant vitamins and carotenoids and age-related cataract
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    Cross-sectional study372 participantsVision Support forLycopene
  352. A randomized, double-masked study on the treatment of retinal vein occlusion with troxerutin
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    Randomized trial53 participantsVision Support forRutin
  353. Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction: A vehicle-controlled, randomized clinical trial.
    Watson SL; Jones LW; Stapleton F; Hinds M; Ng A; Tan J; Alster Y; Bosworth C; Rafaeli O; DePuy V; CELESTIAL STUDY Group · The ocular surface · 2026
    Randomized trial245 participantsVision Support forSelenium
  354. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledVision Support forSelenium
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    Downie LE; Craig JP; Stapleton F; Tan J; Jones LW; Ng A; Hinds M; Bosworth C; Alster Y · The ocular surface · 2025
    Randomized trial245 participantsVision Support forSelenium
  356. AZR-MD-001 0.5% selenium sulfide ophthalmic ointment for the treatment of contact lens discomfort: A vehicle-controlled, randomized, clinical trial.
    Stapleton F; Hinds M; Tan J; Jones L; Chalmers R; Bosworth C; Alster Y · The ocular surface · 2025
    Randomized trial67 participantsVision Support forSelenium
  357. The effect of a biweekly novel selenium sulfide-containing topical treatment in symptomatic contact lens wearers: An exploratory study.
    Stapleton F; Jia T; DePuy V; Bosworth C; Gleeson M; Tan J · The ocular surface · 2025
    Randomized trial14 participantsVision Support forSelenium