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Vitamins D and K with Sea-lodine

Life Extension
4.8
★ ★ ★ ★ ★
(23657 ratings)
Iodine 1000 mcg
Vitamin K 2100 mcg
Product Image
Score71
A focused D, K, and iodine formula with clear purpose, but the aggressive vitamin D and iodine amounts require deliberate, monitored use.
How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
Heart Health
Energy
General Health
Metabolism Boost

Score 71

A focused D, K, and iodine formula with clear purpose, but the aggressive vitamin D and iodine amounts require deliberate, monitored use.
How scoring works
$16.50($0.27 per serving)
Pure Formulas
$ 18.00
Vitacost
$ 18.00
iHerb
$ 18.00
Amazon
$ 16.50
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Analysis

The three-ingredient design is easy to understand and avoids low-value extras. Vitamin D3 has a clearly identified form, while iodine supports thyroid hormone production when intake is inadequate.

The vitamin D amount exceeds the adult daily upper intake level, and iodine is high enough to be unsuitable for routine unsupervised use. Vitamin K is substantial but its subtype is not identified, limiting assessment of its exact role and duration.

This formula fits clinician-guided correction or monitoring better than general wellness use. Warfarin therapy and iodine-sensitive thyroid conditions are the main situations requiring specific caution.

Who is it for
  • Adults with clinician-confirmed need for high-dose vitamin D and iodine
  • People seeking a compact bone and thyroid nutrient formula
Best for
  • Vitamin D support
  • Calcium-handling nutrients
  • Iodine supplementation under guidance

Pros

  • Compact three-ingredient formula
  • Uses vitamin D3
  • One capsule per serving

Cons

  • Vitamin K subtype is not identified
  • Vitamin D exceeds the adult upper intake level
  • Iodine is high for maintenance

Warnings

  • The vitamin D amount exceeds the adult daily upper intake level and should be used with clinical guidance.
  • Iodine may aggravate autoimmune or iodine-sensitive thyroid conditions.
  • Vitamin K can oppose warfarin and other vitamin K antagonists.

Nutrient quality

63 Moderate impact

The compact formula uses a good vitamin D form and substantial amounts. Unspecified vitamin K and aggressive dosing reduce confidence in routine use.

Ingredient transparency

66 High impact

Active amounts and serving count are largely clear. Vague form names and missing excipient details leave important gaps.

Customer satisfaction

73 High impact

The supplied average rating is very strong. Specific feedback is absent, so complaint consistency and purpose fit remain uncertain.

Value for money

86 Highest impact

Low serving cost and a compact formula support good value. Uncertain vitamin K quality keeps the value from being fully convincing.

Report analysis

Goals

Heart Health
Heart Health
Impact
High effect
B Goal FitB Strength of SupportB- CoverageA- Formula Quality
Vitamin K · 2100 mcgVitamin D · 125 mcg

Vitamin D and vitamin K can work together to manage calcium placement, which is relevant to arterial health. The supplied label does not identify the vitamin K forms, so the presence of the preferred MK-7 form cannot be confirmed.

The vitamin amounts are substantial, but the unusually high iodine amount is not a direct heart-health benefit. Iodine at 1000 mcg may disturb thyroid function in susceptible users, and vitamin K can oppose warfarin and other vitamin K antagonist medicines.

Study evidence
Vitamin D Mixed 164 studies
Vitamin K Mixed 62 studies
Energy
Energy
Impact
High effect
B- Goal FitB Strength of SupportC- CoverageB+ Formula Quality
Iodine · 1000 mcgVitamin D · 125 mcg

Iodine supports thyroid hormone production and can matter for energy when iodine status is inadequate. The marine source is identified and paired with vitamins D and K in a compact capsule.

The iodine amount is high for casual maintenance, and source-purity details are limited. People with thyroid disease or iodine-sensitive conditions need individualized guidance before using this level.

Study evidence
Iodine Adverse 3 studies
Vitamin D Supportive 32 studies
General Health
General Health
Impact
High effect
A- Goal FitD Strength of SupportC+ CoverageB+ Formula Quality
Vitamin D · 125 mcgVitamin K · 2100 mcg

Vitamin D3, vitamin K, and iodine address foundational bone, calcium-handling, and thyroid-related nutrient needs. The combination is logically compact and uses ingredients with established physiological roles.

The label does not identify the vitamin K subtype, which prevents a reliable judgment of its activity and quality. The high vitamin D3, iodine, and total vitamin K amounts also make the formula better suited to a defined need than routine unsupervised use; iodine may be unsuitable with some thyroid conditions, and vitamin K may oppose warfarin.

Study evidence
Vitamin D Supportive 115 studies
Vitamin K Supportive 34 studies
Metabolism Boost
Metabolism Boost
Impact
High effect
B Goal FitC- Strength of SupportC- CoverageA- Formula Quality
Vitamin D · 125 mcg

Iodine supports thyroid-hormone production, while vitamin D3 and vitamin K serve complementary nutrient roles. The iodine amount is high and only appropriate when a specific need has been established.

The marine iodine source is named but lacks geographic purity details. High iodine intake may worsen thyroid dysfunction in susceptible users.

Study evidence
Iodine Mixed 17 studies
Bone Health
Bone Health
Impact
Moderate effect
B Goal FitD- Strength of SupportC CoverageD Formula Quality
Vitamin K · 2100 mcgVitamin D · 125 mcg

Vitamin D3 and vitamin K support calcium absorption and placement, but the vitamin K subtype is not disclosed. The large total K amount therefore cannot be judged for MK-7 alignment or appropriate dosing.

Iodine does not directly strengthen the bone formula and its 1,000 mcg amount may disturb thyroid function in susceptible users. Vitamin K can counteract warfarin and related vitamin K antagonists, making clinician-guided consistency important for users of those medicines.

Study evidence
Vitamin D Supportive 202 studies
Vitamin K Supportive 78 studies
Anti-Aging
Anti-Aging
Impact
Moderate effect
C- Goal FitD Strength of SupportD- CoverageB- Formula Quality
Vitamin K · 2100 mcgVitamin D · 125 mcg

Vitamin D3 and vitamin K support skeletal integrity and calcium regulation, while iodine supports thyroid function. These are important age-related systems but do not directly address mitochondrial decline, glycation, or neurological preservation.

The amounts are very high, and the vitamin K form and iodine-blend composition are not disclosed. Vitamin K can counteract warfarin, while 1,000 mcg iodine may disrupt thyroid function and high vitamin D may raise blood calcium with prolonged use.

Study evidence
Vitamin D Supportive 50 studies
Vitamin K Supportive 27 studies

Ingredients

IngredientAmount per serving
Vitamin D3 (Cholecalciferol)
 125 mcg
Vitamin K
2100 mcg
Iodine (Sea-Iodine Complex Blend)
 1000 mcg
Gluten Free Adults 18–50
Report overview
Iodine (Sea-Iodine Complex Blend) · 1000 mcg OverallScore76
C+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB+ Value

A Sea-Iodine complex provides an identified marine source and a high but still tolerable iodine dose. No organic status or clean-water region is stated, leaving marine purity less certain. A single capsule and below-median serving cost support reasonable value for users who specifically need more than a maintenance dose.

View ingredientView products
Vitamin K · 2100 mcg OverallScore2
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

The large vitamin K amount cannot be meaningfully judged because the label does not identify K1, K2, or an MK subtype. A low cost does not establish good value when effective MK-7 content is unknown. The added high-dose vitamin D3 and iodine may suit specific needs, but the unclear vitamin K form makes this a weak fit for targeted MK-7 use.

View ingredientView products
Loading alternative details
84 Performance

D3 + K2

Nature Made
<p>All-trans MK-7 and vitamin D3 use well-defined forms in a focused softgel. Compared with Vitamins D and K with Sea-lodine, the more clearly characterized ingredient approach addresses the unspecified vitamin K form and unusually concentrated vitamin D, vitamin K, and iodine profile more directly, although The active doses are strong, but the vitamin D amount is high and the package provides limited serving value; it does not replace the original's full vitamin D, vitamin K, and iodine combination.</p>
87 Performance

Vitamin D3 25 mcg (1000 IU) & K2 120 mcg

Natural Factors
<p>Moderate vitamin D3 and clinical-range MK-7 make a balanced maintenance formula with excellent consumer support. Compared with Vitamins D and K with Sea-lodine, the more clearly characterized ingredient approach addresses the unspecified vitamin K form and unusually concentrated vitamin D, vitamin K, and iodine profile more directly, although Duplicate K2 source entries create minor label ambiguity, though the softgel and strong value are practical strengths; it does not replace the original's full vitamin D, vitamin K, and iodine combination.</p>
86 Performance

Vitamins D3 2500 IU (62.5 mcg) & K2 120 mcg

NaturesPlus
<p>MK-7 and a substantial vitamin D3 amount provide focused bone and cardiovascular support at a very low serving cost. Compared with Vitamins D and K with Sea-lodine, the more clearly characterized ingredient approach addresses the unspecified vitamin K form and unusually concentrated vitamin D, vitamin K, and iodine profile more directly, although The dry tablet lacks a lipid carrier, and MK-7 requires consistent intake for people using warfarin; it does not replace the original's full vitamin D, vitamin K, and iodine combination.</p>
83 Budget

Organic Kelp

NOW
<p>Organic kelp offers a useful purity signal and flexible liquid use, but the iodine amount is above basic maintenance needs. The lower recurring cost makes it more economical than Vitamins D and K with Sea-lodine, although The appropriate dose and very low serving cost create excellent practical value; it does not replace the original's full vitamin D, vitamin K, and iodine combination.</p>
81 Budget

Icelandic Kelp

Nature's Life
<p>Kelp supplies a clearly stated iodine amount that can support thyroid hormone production when intake is low. The lower recurring cost makes it more economical than Vitamins D and K with Sea-lodine, although The iodine amount is above basic daily needs and can complicate thyroid disease or thyroid medication, so routine use should be deliberate; it does not replace the original's full vitamin D, vitamin K, and iodine combination.</p>
81 Budget

Iodine+

Codeage
<p>A clearly dosed liquid provides convenient iodine support at excellent serving value. The lower recurring cost makes it more economical than Vitamins D and K with Sea-lodine, although The above-maintenance amount offers no assured metabolic benefit when iodine status is adequate and can complicate thyroid management; it does not replace the original's full vitamin D, vitamin K, and iodine combination.</p>
86 Value

Vitamin K2 100 mcg + Vitamin D3 125 mcg

Nutricost
<p>A meaningful MK-7 amount and suitable softgel delivery combine with excellent serving value. The lower recurring cost and stated ingredient strengths create a more favorable quality-to-cost balance than Vitamins D and K with Sea-lodine, although The vitamin D3 amount is concentrated, and inactive ingredients and MK-7 sourcing are not supplied; it does not replace the original's full vitamin D, vitamin K, and iodine combination.</p>
89 Value

Mega D-3 5000 IU & MK-7 180 mcg

NOW
<p>Branded MK-7 and vitamin D3 deliver strong active quality, meaningful amounts, and exceptional consumer support. The lower recurring cost and stated ingredient strengths create a more favorable quality-to-cost balance than Vitamins D and K with Sea-lodine, although High vitamin D remains the main dosing limitation, while the dry capsule lacks stated fat-intake guidance; it does not replace the original's full vitamin D, vitamin K, and iodine combination.</p>
85 Value

Vitamin K2 MenaQ7 100 mcg

AN Amazing Nutrition Amazing Formulas
<p>The focused natto-derived menaquinone-7 formula provides a useful vitamin K option for bone and cardiovascular support with excellent label clarity. The lower recurring cost and stated ingredient strengths create a more favorable quality-to-cost balance than Vitamins D and K with Sea-lodine, although Vitamin K can counteract warfarin and related vitamin K antagonists, so people using those medicines need clinician-directed intake; it does not replace the original's full vitamin D, vitamin K, and iodine combination.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Joint association of serum 25-hydroxyvitamin D concentration and body mass index on the acceleration of clinical biomarker-based biological aging.
    Pan Z; Zeng J; Chen Z; Chen S; Yang J; Li H; Wang S; Wang J; Li N; Gong Y; Liu M; Li C · The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Cohort study389,217 participantsAnti-Aging forVitamin D
  2. Serum 25-Hydroxyvitamin D Levels as an Aging Marker: Strong Associations With Age and All-Cause Mortality Independent From Telomere Length, Epigenetic Age Acceleration, and 8-Isoprostane Levels.
    Schöttker B; Hagen L; Zhang Y; Gào X; Holleczek B; Gao X; Brenner H · The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Cohort study9,940 participantsAnti-Aging forVitamin D
  3. Sex-specific associations of serum 25-hydroxyvitamin D concentrations with incident sarcopenia in older adults: A 2-year follow-up study.
    Song S; Lim JY; Kim M; Won CW; Park HY · The journal of nutrition, health & aging · 2025
    Cohort study1,292 participantsAnti-Aging forVitamin D
  4. Vitamin D deficit is associated with accelerated brain aging in the general population.
    Terock J; Bonk S; Frenzel S; Wittfeld K; Garvert L; Hosten N; Nauck M; Völzke H; Van der Auwera S; Grabe HJ · Psychiatry research. Neuroimaging · 2022
    Cross-sectional study1,865 participantsAnti-Aging forVitamin D
  5. Vitamin D intake is associated with dementia risk in the Washington Heights-Inwood Columbia Aging Project (WHICAP).
    Zhao C; Tsapanou A; Manly J; Schupf N; Brickman AM; Gu Y · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Cohort study1,759 participantsAnti-Aging forVitamin D
  6. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledAnti-Aging General Health forVitamin K
  7. Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
    Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
    Randomized trial30 participantsAnti-Aging forVitamin K
  8. Vitamin K status and cognitive function in healthy older adults.
    Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
    Cross-sectional study320 participantsAnti-Aging forVitamin K
  9. High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
    Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
    Cohort study644 participantsAnti-Aging forVitamin K
  10. Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
    Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
    Cross-sectional study85 participantsAnti-Aging forVitamin K
  11. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  12. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  13. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  14. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  15. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  16. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  17. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  18. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  19. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  20. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  21. Association of radioactive iodine treatment with survivorship symptoms and primary care utilisation in women of reproductive age with thyroid cancer: a retrospective cohort study.
    Devanarayan P; Hartman M; Partin M · Family medicine and community health · 2026
    Cohort study10,882 participantsEnergy forIodine
  22. Energy level and fatigue after surgery for thyroid cancer: A population-based study of patient-reported outcomes.
    Hughes DT; Reyes-Gastelum D; Kovatch KJ; Hamilton AS; Ward KC; Haymart MR · Surgery · 2020
    Cohort study2,584 participantsEnergy forIodine
  23. Health-Related Quality of Life in Differentiated Thyroid Cancer Survivors: A Cross-Sectional Study From Turkey.
    Gültekin A; Kahraman MY; Şengöz T; Şimşek FS · Head & neck · 2026
    Cross-sectional study202 participantsEnergy forIodine
  24. Effect of Vitamin D Supplementation on Fatigue in Multiple Sclerosis: A Systematic Review and Meta-Analysis.
    López-Muñoz P; Torres-Costoso AI; Fernández-Rodríguez R; Guzmán-Pavón MJ; de Arenas-Arroyo SN; Basco-López JÁ; Reina-Gutiérrez S · Nutrients · 2023
    Meta-analysis345 participants5 studies pooledEnergy forVitamin D
  25. Vitamin D Supplementation in Adolescents and Young Adults With Juvenile Systemic Lupus Erythematosus for Improvement in Disease Activity and Fatigue Scores: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Lima GL; Paupitz J; Aikawa NE; Takayama L; Bonfa E; Pereira RM · Arthritis care & research · 2016
    Randomized trial40 participantsEnergy forVitamin D
  26. Vitamin D in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After COVID-19 or Vaccination: A Randomized Controlled Trial.
    Kodama S; Nakata M; Konishi N; Yoshino M; Fujisawa A; Naganuma M; Kobayashi Y; Hirai Y; Kitagawa A; Miyokawa M; Mishima R; Teramukai S; Fukushima M · Nutrients · 2026
    Randomized trial91 participantsEnergy forVitamin D
  27. The effects of vitamin D supplementation on disease activity and fatigue in Libyan rheumatoid arthritis patients.
    Elfituri S · Reumatologia · 2024
    Randomized trial68 participantsEnergy forVitamin D
  28. The effect of home-based aerobic training and vitamin D supplementation on fatigue and quality of life in patients with multiple sclerosis during COVID-19 outbreak.
    Bahmani E; Hoseini R; Amiri E · Science & sports · 2022
    Randomized trial40 participantsEnergy forVitamin D
  29. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  30. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  31. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  32. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  33. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  34. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  35. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  36. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  37. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K
  38. Vitamin D supplementation for cardiometabolic risk markers in pregnant women based on the gestational diabetes mellitus or obesity status : a randomized clinical trial.
    Yin WJ; Wang P; Ma SS; Tao RX; Hu HL; Jiang XM; Zhang Y; Tao FB; Zhu P · European journal of nutrition · 2024
    Randomized trial1,537 participantsHeart Health forVitamin D
  39. Paricalcitol and endothelial function in chronic kidney disease trial.
    Zoccali C; Curatola G; Panuccio V; Tripepi R; Pizzini P; Versace M; Bolignano D; Cutrupi S; Politi R; Tripepi G; Ghiadoni L; Thadhani R; Mallamaci F · Hypertension (Dallas, Tex. : 1979) · 2015
    Randomized trial88 participantsHeart Health forVitamin D
  40. Vitamin D Supplementation, Serum 25(OH)D Concentrations and Cardiovascular Disease Risk Factors: A Systematic Review and Meta-Analysis.
    Mirhosseini N; Rainsbury J; Kimball SM · Frontiers in cardiovascular medicine · 2020
    Meta-analysis81 studies pooledHeart Health forVitamin D
  41. Does vitamin D supplementation modulate metabolic risk factors of cardiovascular disease? A systematic review and meta-analysis of clinical trials.
    Abumweis S; Alqadi S; Al Tarteer A; Alrefai W; Alzoughool F; Jew S; Qudah T · Asia Pacific journal of clinical nutrition · 2026
    Meta-analysis45 studies pooledHeart Health forVitamin D
  42. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisHeart Health forVitamin D
  43. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsHeart Health forVitamin K
  44. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsHeart Health forVitamin K
  45. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K
  46. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsHeart Health forVitamin K
  47. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsHeart Health forVitamin K
  48. Iodine Supplementation Decreases Hypercholesterolemia in Iodine-Deficient, Overweight Women: A Randomized Controlled Trial.
    Herter-Aeberli I; Cherkaoui M; El Ansari N; Rohner R; Stinca S; Chabaa L; von Eckardstein A; Aboussad A; Zimmermann MB · The Journal of nutrition · 2015
    Randomized trial163 participantsMetabolism Boost forIodine
  49. Effect of oral iodized oil on thyroid size and thyroid hormone metabolism in children with concurrent selenium and iodine deficiency.
    Zimmermann MB; Adou P; Torresani T; Zeder C; Hurrell RF · European journal of clinical nutrition · 2000
    Single-arm trial51 participantsMetabolism Boost forIodine
  50. Serum Iodine Concentration as a Biomarker for Individual Iodine Nutrition and Thyroid Function in Pregnant Women: A Cross-Sectional Study in Hubei Province.
    Xu M; Dai X; Wang Z; Guo C; Zhang B; Guo H · Public health nutrition · 2026
    Cross-sectional study1,197 participantsMetabolism Boost forIodine
  51. Iron status influences the efficacy of iodine prophylaxis in goitrous children in Côte d'Ivoire.
    Zimmermann MB · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2002
    OtherMetabolism Boost forIodine
  52. Persistence of goiter despite oral iodine supplementation in goitrous children with iron deficiency anemia in Côte d'Ivoire.
    Zimmermann M; Adou P; Torresani T; Zeder C; Hurrell R · The American journal of clinical nutrition · 2000
    Non-randomized trial109 participantsMetabolism Boost forIodine