Product Image

The Prostate Formula

Real Health
4.7
★ ★ ★ ★ ★
(1710 ratings)
Glutamic Acid 250 mg
Vitamin B6 50 mg
Glycine 250 mg
Vitamin D 600 IU
Ginger
Lysine 250 mg
Calcium 300 mg
Product Image
Score68
Saw palmetto offers a plausible DHT-related pathway, while zinc, vitamin D, selenium, lysine, and pumpkin seed provide supporting nutrition. Unspecified forms, unstandardized powders, and 50 mg of vitamin B6 limit quality and long-term suitability.
How scoring works
Quantity:90 Tablet(s) • (30 servings)
Goals:

Score 68

Saw palmetto offers a plausible DHT-related pathway, while zinc, vitamin D, selenium, lysine, and pumpkin seed provide supporting nutrition. Unspecified forms, unstandardized powders, and 50 mg of vitamin B6 limit quality and long-term suitability.
How scoring works
$15.60($0.52 per serving)
iHerb
$ 15.60
Vitacost
$ 19.79
Report prices

Analysis

Saw palmetto offers a plausible DHT-related pathway, while zinc, vitamin D, selenium, lysine, and pumpkin seed provide supporting nutrition. The product is formulated for prostate support, so many included botanicals are not well targeted to hair.

Unspecified forms, unstandardized powders, and 50 mg of vitamin B6 limit quality and long-term suitability. The label identifies Vitamin D3 (600IU), Vitamin E (100IU), Vitamin B6 (50mg), making the main formulation easier to assess.

The formula is designed for prostate support and has little direct weight-loss relevance. Zinc, selenium, vitamin D, and ginger support general physiology but do not provide meaningful thermogenesis or satiety at these amounts.

Who is it for
  • Adults seeking Hair Health support
  • People comfortable with a multi-ingredient tablet formula
  • Users who can review the ingredient list against medicines and existing supplements
Best for
  • Hair Health
  • Anti-Inflammatory Support
  • General Health

Pros

  • Saw palmetto offers a plausible DHT-related pathway, while zinc, vitamin D, selenium, lysine, and pumpkin seed provide supporting nutrition
  • Strongest formulation fit is Hair Health
  • Main label amounts are disclosed for Vitamin D3, Vitamin E, Vitamin B6
  • Includes a meaningful Glutamic Acid component

Cons

  • Unspecified forms, unstandardized powders, and 50 mg of vitamin B6 limit quality and long-term suitability
  • Weak fit for Weight Loss
  • Several secondary ingredients add breadth without equally strong dose or form support
  • Long ingredient list makes the combined effects and trade-offs harder to predict

Warnings

  • The unstandardized form and unsuitable delivery format limit expected active quality.
  • The high vitamin B6 amount may be unsuitable for long-term stacking, and most active forms are not disclosed.

Nutrient quality

58 Moderate impact

Saw palmetto, zinc, selenium, and amino acids broadly fit prostate-focused use. Unspecified forms, modest secondary amounts, and high vitamin B6 reduce quality and long-term balance.

.

Ingredient transparency

75 High impact

Most active ingredients and their amounts are clearly listed. Daily directions, a complete excipient panel, and some form details are missing from the supplied data.

.

Customer satisfaction

68 High impact

The aggregate rating is favorable and supported by solid feedback volume. Complaint-level experiences are unavailable, so repeated drawbacks and purpose fit remain uncertain.

.

Value for money

71 High impact

The serving cost is reasonable for the documented core ingredients. Form, disclosure, or focus limitations keep category value from standing out.

.
Report analysis

Goals

Hair Health
Hair Health
Impact
Moderate effect
C Goal FitC Strength of SupportC- CoverageC Formula Quality
Vitamin D · 600 IUZinc · 15 mgLysine · 250 mg

Saw palmetto offers a plausible DHT-related pathway, while zinc, vitamin D, selenium, lysine, and pumpkin seed provide supporting nutrition. The product is formulated for prostate support, so many included botanicals are not well targeted to hair.

Saw palmetto is present at a commonly used total amount, but it is a berry powder rather than a clearly standardized lipid extract. The high vitamin B6 amount and saw palmetto make long-term use unsuitable to stack casually with other B-complex or hormone-active products.

Study evidence
Lysine Supportive 1 study
Saw Palmetto Supportive 5 studies
Selenium Disputed 7 studies
Vitamin D Disputed 34 studies
Zinc Supportive 22 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Moderate effect
C Goal FitD+ Strength of SupportC+ CoverageC+ Formula Quality
Vitamin D · 600 IUGlycine · 250 mgVitamin E · 100 IU

Ginger, vitamin E, vitamin D3, selenium, pomegranate, and quercetin provide several anti-inflammatory and antioxidant mechanisms. Most supporting botanicals are too modest to match the ginger contribution.

The ginger amount is moderate, but gingerol standardization and vitamin E form are not disclosed. The prostate-focused blend is coherent, though its broad ingredient list offers uneven depth.

Study evidence
Ginger Supportive 30 studies
Selenium Supportive 34 studies
Vitamin D Supportive 101 studies
Vitamin E Supportive 20 studies
General Health
General Health
Impact
Moderate effect
C- Goal FitD+ Strength of SupportC- CoverageB Formula Quality
Vitamin D · 600 IUGlycine · 250 mgSelenium · 100 mcgZinc · 15 mg

Vitamin D, zinc, selenium, vitamin E, and several amino acids provide some foundational nutritional support. The botanical and amino-acid combination is logically oriented toward prostate health rather than broad daily wellness.

General-health coverage is limited because the formula omits most vitamins and minerals and uses modest amounts of several secondary ingredients. The high vitamin B6 amount may be unsuitable for long-term stacking, and most active forms are not disclosed.

Study evidence
Selenium Supportive 70 studies
Vitamin D Supportive 115 studies
Zinc Supportive 60 studies
Testosterone Support
Testosterone Support
Impact
Moderate effect
D+ Goal FitD+ Strength of SupportC CoverageD+ Formula Quality
Zinc · 15 mgVitamin D · 600 IU

Zinc, vitamin D3, vitamin B6, saw palmetto, and nettle create a broad male-health context. Zinc provides the clearest foundational support for steroidogenesis.

Vitamin D is low, nettle uses the less relevant leaf powder, and its amount remains below targeted use. Saw palmetto primarily affects androgen metabolism and does not establish that the formula raises testosterone.

Study evidence
Vitamin D Supportive 56 studies
Zinc Disputed 7 studies
Immunity
Immunity
Impact
Moderate effect
C- Goal FitD+ Strength of SupportD+ CoverageD Formula Quality
Zinc · 15 mgVitamin D · 600 IUSelenium · 100 mcg

Vitamin D3, zinc, selenium, ginger, and quercetin offer some immune-relevant activity. The prostate-focused botanicals dominate the formula and the immune ingredients are not optimized for acute or broad immune support.

Coverage reaches vitamin D signaling, zinc activity, selenium antioxidant function, and minor botanical pathways. The formula is coherent for prostate support but only partly aligned with an immune goal.

Study evidence
Ginger Not classified

No linked studies yet.

Selenium Mixed 37 studies
Vitamin D Supportive 85 studies
Zinc Supportive 73 studies
Nail Health
Nail Health
Impact
Moderate effect
D+ Goal FitD Strength of SupportD+ CoverageD Formula Quality

Zinc, selenium, D3, glycine, lysine, vitamin C, and B6 provide only indirect nutritional and amino-acid support. The amino acids are not the main sulfur-rich building blocks of nail keratin, and no biotin or silicon is present.

The formula is designed for prostate health and lacks a direct nail-plate mechanism. Moderate nutrient amounts cannot substitute for collagen, keratin, cysteine, methionine, or targeted biotin.

Study evidence
Selenium Adverse 1 study
Vitamin D Supportive 8 studies
Zinc No effect 1 study

Ingredients

IngredientAmount per serving
Vitamin D3
600 IU
Vitamin E
100 IU
Vitamin B6
50 mg
Calcium
300 mg
Zinc
15 mg
Selenium
100 mcg
Saw Palmetto berry powder
320 mg
Ginger root powder
270 mg
L-Glutamic Acid
250 mg
L-Glycine
250 mg
L-Lysine Hydrochloride
250 mg
Pumpkin seed powder
100 mg
Stinging Nettle leaf powder
100 mg
Pomegranate fruit extract
60 mg
Ginger root extract
30 mg
Quercetin
15 mg
Men 50+ Men 18–50
Report overview
Glutamic Acid · 250 mg OverallScore94
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value
L-glutamic acid is well aligned with the prostate-support format and provided at a substantial dose. Exact label disclosure makes the ingredient contribution clear. The serving cost is moderately above the collection median but remains reasonable for a multi-ingredient prostate formula.
View ingredientView products
Vitamin B6 · 50 mg OverallScore66
F Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value

The 50 mg B6 amount fits the preferred range, but the chemical form is not disclosed. The three-tablet serving is manageable, though missing form information limits confidence in bioavailability. The broad formula remains cost efficient for its ingredient count.

View ingredientView products
Glycine · 250 mg OverallScore64
C Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyB- Value

Standard L-glycine is clearly listed, but hard-pressed tablets are less flexible than powder or capsules. The 250 mg amount is low on its own, though glycine works alongside glutamic acid, lysine, saw palmetto, and other prostate-focused ingredients. Long-term use warrants care because the formula contains 50 mg of vitamin B6, an amount associated with nerve symptoms in some users.

View ingredientView products
Loading alternative details
81 Performance

Prostate Wellness

Bio Nutrition
<p>Saw palmetto, beta-sitosterol, nettle, pygeum, pumpkin seed, and lycopene are all disclosed at substantial amounts in a coherent prostate formula. Its 20 mg B6 is still elevated but notably less aggressive than the original’s 50 mg, while zinc citrate improves mineral form quality.</p>
77 Budget

Prostate Essentials

Swanson
<p>Zinc picolinate, standardized saw palmetto, nettle, pumpkin, amino acids, and beta-sitosterol retain a prostate-focused core at much lower recurring cost. Several botanical and amino-acid amounts are modest, while saw palmetto and ginseng may add bleeding risk with relevant medicines.</p>
65 Budget

ProFlo Prostate Health Complex

Urinozinc
<p>A meaningful standardized saw palmetto amount plus vitamin D, vitamin E, zinc, and selenium preserve the central prostate theme at slightly lower cost. An undisclosed blend, oxide minerals, and token lycopene make the label less transparent than the original.</p>
40 Value

Femesse

Arthur Andrew Medical
<p>Natural vitamin E and selenomethionine improve two shared nutrient forms, but the formula is not a credible prostate-focused substitute. Two large proprietary blends hide most ingredients, and assertive B6 plus weak goal alignment prevent dependable value.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Vitamin D3 Supplementation on Body Composition in the VITamin D and OmegA-3 TriaL (VITAL).
    Chou SH; Murata EM; Yu C; Danik J; Kotler G; Cook NR; Bubes V; Mora S; Chandler PD; Tobias DK; Copeland T; Buring JE; Manson JE; LeBoff MS · The Journal of clinical endocrinology and metabolism · 2021
    Randomized trial771 participantsWeight Loss forVitamin D
  2. Vitamin D Supplementation and Genetic Polymorphisms Impact on Weight Loss Diet Outcomes in Caucasians: A Randomized Double-Blind Placebo-Controlled Clinical Study.
    Xenos K; Papasavva M; Raptis A; Katsarou MS; Drakoulis N · Frontiers in medicine · 2022
    Randomized trial125 participantsWeight Loss forVitamin D
  3. Zinc Supplementation and Body Weight: A Systematic Review and Dose-Response Meta-analysis of Randomized Controlled Trials.
    Abdollahi S; Toupchian O; Jayedi A; Meyre D; Tam V; Soltani S · Advances in nutrition (Bethesda, Md.) · 2021
    Meta-analysis1,438 participants27 studies pooledWeight Loss forZinc
  4. Effect of L-arginine and selenium added to a hypocaloric diet enriched with legumes on cardiovascular disease risk factors in women with central obesity: a randomized, double-blind, placebo-controlled trial.
    Alizadeh M; Safaeiyan A; Ostadrahimi A; Estakhri R; Daneghian S; Ghaffari A; Gargari BP · Annals of nutrition & metabolism · 2012
    Randomized trial84 participantsWeight Loss forSelenium
  5. Significant Beneficial Association of High Dietary Selenium Intake with Reduced Body Fat in the CODING Study.
    Wang Y; Gao X; Pedram P; Shahidi M; Du J; Yi Y; Gulliver W; Zhang H; Sun G · Nutrients · 2016
    Cross-sectional study3,214 participantsWeight Loss forSelenium
  6. Impact of ginger supplementation on obesity indices and Adipokine profiles in adults: A GRADE-based systematic review and dose-response meta-analysis of randomized controlled trials.
    Rjabi S; Seyedhatami SS; Makhtoomi M; Ahmadi MR; Alimohamadi S; Aliabadi E; Talakesh S; Nouri M; Zamani B; Askarpour M · Complementary therapies in medicine · 2025
    Meta-analysis36 participants36 studies pooledWeight Loss forGinger
  7. The effect of vitamin D supplementation on glucose metabolism in type 2 diabetes mellitus: A systematic review and meta-analysis of intervention studies.
    Lee CJ; Iyer G; Liu Y; Kalyani RR; Bamba N; Ligon CB; Varma S; Mathioudakis N · Journal of diabetes and its complications · 2018
    Meta-analysis3,324 participants29 studies pooledMetabolism Boost forVitamin D
  8. Effects of different vitamin D supplements on body fat distribution and glucolipid metabolism in patients with obesity-associated metabolic syndrome: A meta-analysis.
    Huang Q; Zhan J; Gui Y; Ma M; Li E · Medicine · 2026
    Meta-analysis50 studies pooledMetabolism Boost forVitamin D
  9. Zinc and the Innovative Zinc-α2-Glycoprotein Adipokine Play an Important Role in Lipid Metabolism: A Critical Review.
    Banaszak M; Górna I; Przysławski J · Nutrients · 2021
    Narrative reviewMetabolism Boost forZinc
  10. The effect of curcumin and zinc co-supplementation on glycemic parameters in overweight or obese prediabetic subjects: A phase 2 randomized, placebo-controlled trial with a multi-arm, parallel-group design.
    Karandish M; Mozaffari-Khosravi H; Mohammadi SM; Cheraghian B; Azhdari M · Phytotherapy research : PTR · 2021
    Randomized trial84 participantsMetabolism Boost forZinc
  11. Selenium and Type 2 Diabetes: Systematic Review.
    Kohler LN; Foote J; Kelley CP; Florea A; Shelly C; Chow HS; Hsu P; Batai K; Ellis N; Saboda K; Lance P; Jacobs ET · Nutrients · 2019
    Meta-analysis16 studies pooledMetabolism Boost forSelenium
  12. Effects of selenium supplementation on glucose homeostasis, inflammation, and oxidative stress in gestational diabetes: Randomized, double-blind, placebo-controlled trial.
    Asemi Z; Jamilian M; Mesdaghinia E; Esmaillzadeh A · Nutrition (Burbank, Los Angeles County, Calif.) · 2016
    Randomized trial70 participantsMetabolism Boost Anti-Inflammatory Support forSelenium
  13. Ginger supplementation does not increase energy expenditure in female adults.
    Braga Tibaes JR; Martins LB; Rodrigues AMDS; Amaral MHA; Teixeira AL; Ferreira AVM · Nutrition (Burbank, Los Angeles County, Calif.) · 2022
    Randomized trial66 participantsMetabolism Boost forGinger
  14. The effect of ginger consumption on glycemic status, lipid profile and some inflammatory markers in patients with type 2 diabetes mellitus.
    Arablou T; Aryaeian N; Valizadeh M; Sharifi F; Hosseini A; Djalali M · International journal of food sciences and nutrition · 2015
    Randomized trial70 participantsMetabolism Boost forGinger
  15. The effect of ginger supplementation on serum C-reactive protein, lipid profile and glycaemia: a systematic review and meta-analysis.
    Mazidi M; Gao HK; Rezaie P; Ferns GA · Food & nutrition research · 2022
    Meta-analysis9 studies pooledAnti-Inflammatory Support forGinger
  16. Ginger supplementation and metabolic health: an umbrella review of meta-analyses of randomized trials.
    Musazadeh V; Morvaridi M; Hosseini-Roknabadi SM; Mahmoudinezhad M; Jafari A; Shidfar F · Diabetology & metabolic syndrome · 2026
    Meta-analysis43,570 participants36 studies pooledAnti-Inflammatory Support forGinger
  17. Effect of Ginger Supplementation on Proinflammatory Cytokines in Older Patients with Osteoarthritis: Outcomes of a Randomized Controlled Clinical Trial.
    Mozaffari-Khosravi H; Naderi Z; Dehghan A; Nadjarzadeh A; Fallah Huseini H · Journal of nutrition in gerontology and geriatrics · 2017
    Randomized trial120 participantsAnti-Inflammatory Support forGinger
  18. Effects of Ginger Supplementation on Markers of Inflammation and Functional Capacity in Individuals with Mild to Moderate Joint Pain.
    Broeckel J; Estes L; Leonard M; Dickerson BL; Gonzalez DE; Purpura M; Jäger R; Sowinski RJ; Rasmussen CJ; Kreider RB · Nutrients · 2025
    Randomized trial30 participantsAnti-Inflammatory Support forGinger
  19. The effect of ginger supplementation on some immunity and inflammation intermediate genes expression in patients with active Rheumatoid Arthritis.
    Aryaeian N; Shahram F; Mahmoudi M; Tavakoli H; Yousefi B; Arablou T; Jafari Karegar S · Gene · 2019
    Randomized trial70 participantsAnti-Inflammatory Support forGinger
  20. Selenium and the course of mild Graves' orbitopathy.
    Marcocci C; Kahaly GJ; Krassas GE; Bartalena L; Prummel M; Stahl M; Altea MA; Nardi M; Pitz S; Boboridis K; Sivelli P; von Arx G; Mourits MP; Baldeschi L; Bencivelli W; Wiersinga W; European Group on Graves' Orbitopathy · The New England journal of medicine · 2011
    Randomized trial159 participantsAnti-Inflammatory Support forSelenium
  21. Selenium Supplementation Affects Insulin Resistance and Serum hs-CRP in Patients with Type 2 Diabetes and Coronary Heart Disease.
    Farrokhian A; Bahmani F; Taghizadeh M; Mirhashemi SM; Aarabi MH; Raygan F; Aghadavod E; Asemi Z · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2017
    Randomized trial60 participantsAnti-Inflammatory Support forSelenium
  22. The effects of selenium supplementation on cardiovascular risk factors in patients with metabolic diseases ‒ A systematic review and meta-analysis of randomized controlled trials.
    Qiu W; Huang N; Zhang K; Qiu H; Guo Z; Han F; Sun X; Hou N; Kan C · Nutricion hospitalaria · 2026
    Meta-analysis656 participants11 studies pooledAnti-Inflammatory Support forSelenium
  23. Effects of Selenium Supplementation on Metabolic Status in Patients Undergoing for Coronary Artery Bypass Grafting (CABG) Surgery: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Kamali A; Amirani E; Asemi Z · Biological trace element research · 2020
    Randomized trial33 participantsAnti-Inflammatory Support forSelenium
  24. Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
    Zhou A; Hyppönen E · International journal of epidemiology · 2023
    Observational study294,970 participantsAnti-Inflammatory Support forVitamin D
  25. Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
    El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  26. Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
    Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  27. Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
    Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
    Cross-sectional study9,809 participantsAnti-Inflammatory Support forVitamin D
  28. Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
    Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
    Cohort study3,072 participantsAnti-Inflammatory Support forVitamin D
  29. Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
    Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
    Randomized trial110 participantsAnti-Inflammatory Support forVitamin E
  30. Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
    Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
    Meta-analysis495 participants12 studies pooledAnti-Inflammatory Support forVitamin E
  31. Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
    Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
    Meta-analysis46 studies pooledAnti-Inflammatory Support forVitamin E
  32. Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
    Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
    Meta-analysis8 studies pooledAnti-Inflammatory Support forVitamin E
  33. Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
    Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
    Randomized trial71 participantsAnti-Inflammatory Support forVitamin E
  34. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  35. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  36. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health forSelenium
  37. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  38. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  39. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  40. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  41. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  42. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  43. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  44. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  45. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  46. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  47. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  48. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  49. Causes of hair loss and the developments in hair rejuvenation.
    Rushton DH; Norris MJ; Dover R; Busuttil N · International journal of cosmetic science · 2010
    Narrative reviewHair Health forLysine
  50. The Safety and Efficacy of a Proprietary Bioactive Fatty Acids Extract From Saw Palmetto (Serenoa repens) for Promoting Hair Growth and Reducing Hair Loss in Adults With Self-Perceived Thinning Hair: 90-Day Results.
    Ablon G · Journal of cosmetic dermatology · 2025
    Randomized trial60 participantsHair Health forSaw Palmetto
  51. Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
    Zhou L; Zhu W; Chen Y · Frontiers in nutrition · 2026
    Meta-analysis1,658 participants19 studies pooledHair Health forSaw Palmetto
  52. The Safety and Efficacy of a Novel Saw Palmetto (Serenoa repens) Extract for Promoting Hair Growth in Adults With Self-Perceived Thinning Hair: 180-Day Results.
    Ablon G · Journal of cosmetic dermatology · 2026
    Randomized trial60 participantsHair Health forSaw Palmetto
  53. Beyond Minoxidil: Off-Label Therapies for Male Androgenetic Alopecia-A Systematic Review with Network Meta-Analyses.
    Gupta AK; Compton SAH; Liddy A; Talukder M; Wang T; Bamimore MA · Medicina (Kaunas, Lithuania) · 2026
    Meta-analysis50 participants23 studies pooledHair Health forSaw Palmetto
  54. Comparitive effectiveness of finasteride vs Serenoa repens in male androgenetic alopecia: a two-year study.
    Rossi A; Mari E; Scarno M; Garelli V; Maxia C; Scali E; Iorio A; Carlesimo M · International journal of immunopathology and pharmacology · 2013
    Non-randomized trial100 participantsHair Health forSaw Palmetto
  55. Beyond Efficacy: 0.6% Selenium Disulfide Shampoo Matches 2% Ketoconazole for Seborrheic Dermatitis with Superior Cosmesis.
    Farris PK; Barbosa V; Houshman EB; Kovylkina N · Journal of drugs in dermatology : JDD · 2026
    Randomized trial87 participantsHair Health forSelenium
  56. Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis.
    Turcu G; Artenie C; Nowicka D; Arenbergerová M; Lazaridou E; Khobzei K; Ataseven A; Part M; Leclerc-Mercier S · European journal of dermatology : EJD · 2023
    Observational study1,407 participantsHair Health forSelenium
  57. A Comparative Randomized Clinical Study Assessing the Efficacy of a 1% Selenium Disulfide-Based Shampoo versus 2% Ketoconazole Shampoo in Subjects with Moderate to Severe Scalp Seborrheic Dermatitis.
    Barbosa V; Melo DF; Vañó-Galván S; Lutchmanen-Kolanthan V; Sant'Anna B; Leclerc-Mercier S; Reygagne P · Skin appendage disorders · 2025
    Randomized trial64 participantsHair Health forSelenium
  58. Changes of serum trace elements level in patients with alopecia areata: A meta-analysis.
    Jin W; Zheng H; Shan B; Wu Y · The Journal of dermatology · 2018
    Meta-analysis764 participantsHair Health forSelenium
  59. Scientific opinion on the tolerable upper intake level for selenium.
    EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA); Turck D; Bohn T; Castenmiller J; de Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Peláez C; Pentieva K; Siani A; Thies F; Tsabouri S; Vinceti M; Aggett P; Crous Bou M; Cubadda F; Ciccolallo L; de Sesmaisons Lecarré A; Fabiani L; Titz A; Naska A · EFSA journal. European Food Safety Authority · 2023
    Systematic reviewHair Health forSelenium
  60. Increased prevalence of vitamin D deficiency in patients with alopecia areata: a systematic review and meta-analysis.
    Lee S; Kim BJ; Lee CH; Lee WS · Journal of the European Academy of Dermatology and Venereology : JEADV · 2018
    Meta-analysis2,039 participants14 studies pooledHair Health forVitamin D
  61. Intralesional vitamin D3 in treatment of alopecia areata: A randomized controlled clinical trial.
    Rashad AF; Elgamal E; Fouda I · Journal of cosmetic dermatology · 2022
    Randomized trial60 participantsHair Health forVitamin D
  62. Vitamin D and its Analogs in Treatment of Mild to Moderate Alopecia Areata: Systematic Review and Meta-Analysis.
    Alsaati AA; Kaliyadan F; Alsaadoun D; Alzakry LM; Alzabadin RA; Hakami TH; Rubaian NFB · Indian dermatology online journal · 2025
    Meta-analysisHair Health forVitamin D
  63. Topical calcipotriol vs narrowband ultraviolet B in treatment of alopecia areata: a randomized-controlled trial.
    El Taieb MA; Hegazy EM; Ibrahim HM; Osman AB; Abualhamd M · Archives of dermatological research · 2020
    Randomized trial60 participantsHair Health forVitamin D
  64. Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis.
    Chen Y; Dong X; Wang Y; Li Y; Xiong L; Li L · Journal of cosmetic dermatology · 2024
    Meta-analysis10,670 participants23 studies pooledHair Health forVitamin D
  65. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  66. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  67. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  68. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  69. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  70. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  71. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  72. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  73. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  74. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium
  75. Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
    Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
    Meta-analysis11,321 participants25 studies pooledImmunity forVitamin D
  76. Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
    Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
    Meta-analysis4,859 participants10 studies pooledImmunity forVitamin D
  77. Vitamin D3 and deconvoluting a rash.
    Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
    Randomized trial28 participantsImmunity forVitamin D
  78. Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
    Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
    Randomized trial110 participantsImmunity forVitamin D
  79. Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
    Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
    Meta-analysis50,554 participants65 studies pooledImmunity forVitamin D
  80. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  81. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  82. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  83. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  84. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  85. Acute selenium toxicity associated with a dietary supplement.
    MacFarquhar JK; Broussard DL; Melstrom P; Hutchinson R; Wolkin A; Martin C; Burk RF; Dunn JR; Green AL; Hammond R; Schaffner W; Jones TF · Archives of internal medicine · 2010
    Observational study201 participantsNail Health forSelenium
  86. Recommendations for the definition, evaluation, and treatment of nail psoriasis in adult patients with no or mild skin psoriasis: A dermatologist and nail expert group consensus.
    Rigopoulos D; Baran R; Chiheb S; Daniel CR; Di Chiacchio N; Gregoriou S; Grover C; Haneke E; Iorizzo M; Pasch M; Piraccini BM; Rich P; Richert B; Rompoti N; Rubin AI; Singal A; Starace M; Tosti A; Triantafyllopoulou I; Zaiac M · Journal of the American Academy of Dermatology · 2019
    Guideline / consensusNail Health forVitamin D
  87. Vitamins for the Management of Nail Disease: A Literature Review.
    Curtis KL; Lipner SR · Skin appendage disorders · 2025
    Narrative reviewNail Health forVitamin D
  88. Nail involvement in psoriatic arthritis.
    Sobolewski P; Walecka I; Dopytalska K · Reumatologia · 2019
    Narrative reviewNail Health forVitamin D
  89. Psoriasis treatment in difficult locations: scalp, nails, and intertriginous areas.
    Wozel G · Clinics in dermatology · 2009
    Narrative reviewNail Health forVitamin D
  90. Nail psoriasis: clinical presentation and best practice recommendations.
    Edwards F; de Berker D · Drugs · 2010
    Narrative reviewNail Health forVitamin D
  91. Vitamins and minerals: their role in nail health and disease.
    Scheinfeld N; Dahdah MJ; Scher R · Journal of drugs in dermatology : JDD · 2007
    Narrative reviewNail Health forZinc
  92. Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
    Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
    Randomized trial90 participantsTestosterone Support forVitamin D
  93. Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
    Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
    Randomized trial60 participantsTestosterone Support forVitamin D
  94. Association between plasma 25-OH vitamin D and testosterone levels in men.
    Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
    Case-control study1,362 participantsTestosterone Support forVitamin D
  95. Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
    Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
    Other4,254 participantsTestosterone Support forVitamin D
  96. Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
    Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
    Cohort study643 participantsTestosterone Support forVitamin D
  97. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
    Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
    Cross-sectional study219 participantsTestosterone Support forZinc
  98. Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
    Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
    Scoping reviewTestosterone Support forZinc
  99. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
    Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
    Narrative reviewTestosterone Support forZinc
  100. Clinical, endocrinological and biochemical effects of zinc deficiency.
    Prasad AS · Clinics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  101. Clinical, endocrinologic, and biochemical effects of zinc deficiency.
    Prasad AS · Special topics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc