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Chelated Calcium Magnesium 1:1

4.7
★ ★ ★ ★ ★
(510 ratings)
Calcium 500 mg
Magnesium 500 mg
Product Image
Score75
Useful citrate and glycinate forms plus good value are offset by ambiguous repeated amounts, lower-grade forms, and four tablets per serving.
How scoring works
Tablet
Quantity:240 Tablet(s) • (60 servings)
Goals:
Bone Health
Energy
General Health
Heart Health
Stress Relief

Score 75

Useful citrate and glycinate forms plus good value are offset by ambiguous repeated amounts, lower-grade forms, and four tablets per serving.
How scoring works
$28.18($0.46 per serving)
iHerb
$ 28.18
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Analysis

Calcium and magnesium are presented in a one-to-one formula with citrate and glycinate among the listed forms. Those organic forms are well suited to regular supplementation.

Each mineral appears under multiple forms with the same 500 mg quantity, making the elemental total and form proportions difficult to interpret. Calcium carbonate and magnesium oxide reduce the quality of an otherwise chelate-focused label.

Four tablets per serving are inconvenient, though the bottle offers good value. The potentially substantial magnesium exposure may need division to improve digestive tolerance.

Who is it for
  • Adults seeking a one-to-one calcium-magnesium formula
  • People who value citrate and glycinate forms
Best for
  • Balanced mineral support
  • Users willing to divide a high-tablet serving

Pros

  • Includes citrate and glycinate forms
  • Balanced calcium-magnesium positioning
  • Good serving value

Cons

  • Repeated amounts obscure form distribution
  • Includes calcium carbonate and magnesium oxide
  • Requires four tablets

Warnings

  • The potentially large magnesium amount may cause loose stools or cramping
  • Ambiguous calcium totals should be checked against dietary intake
  • Separate calcium from thyroid hormone, bisphosphonates, and some antibiotics

Nutrient quality

84 Highest impact

Citrate and glycinate strengthen both mineral blends, though carbonate and magnesium oxide lower the average form quality, and the stated 500 mg amounts provide substantial calcium and magnesium, though divided use may improve tolerance. The substantial mineral amounts may require divided use for comfort and efficient absorption, while calcium and magnesium form a coherent mineral-support combination without mismatched actives.

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Ingredient transparency

69 High impact

Total mineral amounts are shown, but repeated amounts across forms make each form contribution unclear, and no proprietary blend hides the amount of a listed core mineral. Serving count is supplied, but complete daily-use directions are not provided, while inactive ingredients and excipients are not included in the supplied label details.

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Customer satisfaction

71 High impact

The supplied average rating is strong, and moderate review volume provides a reasonable evidence base. Specific review themes are unavailable, so repeated negatives and real-world fit remain uncertain.

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Value for money

76 High impact

Useful amounts and some favorable forms support fair value despite clear quality limitations, and the high serving cost weakens value relative to similar mineral formulas. The small sodium amount is incidental and does not materially dilute the mineral formula, while the product is reasonably competitive but lacks a clear quality or value advantage.

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Goals

Bone Health
Bone Health
Impact
Highest effect
A Goal FitB+ Strength of SupportB CoverageB+ Formula Quality
Magnesium · 500 mgCalcium · 500 mg

Calcium and magnesium provide two important mineral components for bone structure and remodeling. Citrate and glycinate forms improve the blend, although included oxide and carbonate forms reduce absorption quality.

The balanced mineral focus offers more coverage than a single-mineral supplement. Vitamin D, vitamin K, and protein-matrix support are absent, so the formula remains incomplete for broader skeletal needs.

Study evidence
Calcium Supportive 144 studies
Magnesium Supportive 48 studies
Energy
Energy
Impact
Highest effect
A Goal FitB Strength of SupportC+ CoverageA- Formula Quality
Magnesium · 500 mg

Balanced calcium and magnesium support bone, muscle, nerve, and metabolic functions through a focused mineral formula. Citrate and glycinate improve form quality, while carbonate and oxide make absorption less consistent.

The equal mineral ratio avoids excessive calcium relative to magnesium and all active totals are clearly stated. The high magnesium amount may cause loose stools or abdominal discomfort in sensitive users.

Study evidence
Magnesium Supportive 4 studies
General Health
General Health
Impact
Highest effect
A Goal FitB- Strength of SupportC+ CoverageA- Formula Quality
Magnesium · 500 mg

Calcium and magnesium provide relevant foundational support for muscle, nerve, bone, and energy functions. Citrate and glycinate improve the mineral blend, but oxide and carbonate lower absorption quality.

The amounts are substantial and clearly stated, although the magnesium serving is higher than many people need from a supplement. A four-tablet serving may be inconvenient, and the magnesium amount may cause diarrhea or cramping in sensitive users.

Study evidence
Magnesium Supportive 114 studies
Heart Health
Heart Health
Impact
High effect
B- Goal FitB+ Strength of SupportD+ CoverageC+ Formula Quality
Magnesium · 500 mg

A 500 mg magnesium amount supports normal heart rhythm and vascular tone through citrate, glycinate, and oxide. The favorable forms improve the mix, but oxide is included and the contribution from each form is not separated.

An equal 500 mg calcium amount makes the four-tablet formula more aligned with general bone-mineral support than cardiovascular needs. Substantial calcium and magnesium may cause digestive discomfort and require caution in people with impaired kidney function.

Study evidence
Magnesium Supportive 158 studies
Stress Relief
Stress Relief
Impact
High effect
C+ Goal FitB Strength of SupportD+ CoverageC+ Formula Quality
Magnesium · 500 mg

Magnesium provides relevant foundational support for nervous-system regulation and may help with stress-related tension. The disclosed amount appears substantial enough to contribute meaningfully.

Citrate and glycinate support absorption, but included oxide keeps the blend mixed. Added calcium contributes little direct stress support and makes the formula less focused.

Study evidence
Magnesium Supportive 13 studies
Cardiovascular Support
Cardiovascular Support
Impact
Moderate effect
B- Goal FitB+ Strength of SupportD+ CoverageD- Formula Quality
Magnesium · 500 mg

Magnesium supports vascular tone and normal cardiac rhythm, giving it a direct but narrow cardiovascular role. Human evidence supports magnesium for blood-pressure and rhythm support, especially when intake is inadequate.

The disclosed magnesium amount is substantial and reaches a commonly used supplemental range. Citrate and glycinate improve absorption, though magnesium oxide keeps the overall form quality mixed.

Study evidence
Magnesium Supportive 123 studies

Ingredients

IngredientAmount per serving
Calcium (Calcium Citrate, Calcium Glycinate, Calcium Carbonate)
 500 mg
Magnesium (Magnesium Citrate, Magnesium Glycinate, Magnesium Oxide)
 500 mg
Sodium
15 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Halal Vegetarian
Report overview
Calcium (Calcium Citrate, Calcium Glycinate, Calcium Carbonate) · 500 mg OverallScore87
A Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value

The 500 mg serving combines citrate, glycinate, and carbonate in an absorption-efficient amount. Chelated and citrate forms strengthen a blend that also contains basic carbonate. The balanced Calcium and magnesium formula carries an average cost.

View ingredientView products
Magnesium (Magnesium Citrate, Magnesium Glycinate, Magnesium Oxide) · 500 mg OverallScore56
D- Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyD- Value
+1

Citrate and glycinate improve the blend, but magnesium oxide keeps absorption quality mixed. The elemental amount is clear and the calcium-to-magnesium balance avoids the stated competition penalty. Its serving cost is slightly above the collection median without a patented material to justify the premium.

View ingredientView products
Loading alternative details
94 Performance

Cal/Mag 500 mg/250 mg

NaturesPlus
<p>Chelated calcium and magnesium provide a balanced, focused mineral formula with stronger form quality than products relying heavily on carbonate or oxide. The simple serving is easy to assess, though vitamin D and vitamin K are not included.</p>
92 Performance

Magnesium Bisglycinate Chelate

Healthy Origins
<p>TRAACS magnesium bisglycinate provides a well-absorbed form at a useful amount and avoids the weaker oxide forms found in many combinations. The powder covers magnesium only, so a separate calcium source is needed when both minerals are intended.</p>
92 Performance

Calcium Citrate Pure Powder

NOW
<p>Calcium citrate provides a well-absorbed, clearly disclosed calcium source in an adjustable powder. The focused formula omits magnesium, vitamin D, and vitamin K, so it works better as a targeted calcium option than as a complete replacement.</p>
87 Budget

600 Calcium Supplement

21st Century
<p>A straightforward calcium carbonate tablet provides a much lower-cost source of calcium at a practical supplemental amount. Carbonate works best with food, and the formula omits magnesium, vitamin D, and other bone-supporting cofactors found in broader products.</p>
86 Budget

Calcium Carbonate

NOW
<p>A pure calcium carbonate powder offers substantial calcium with excellent serving value and no unrelated actives. Food and stomach acid aid carbonate absorption, while the calcium-only design leaves magnesium and vitamin D uncovered.</p>
85 Budget

Calcium 600 with Vitamin D3

Nature's Bounty
<p>Calcium with vitamin D3 provides an economical, meaningfully dosed bone-support pairing. Calcium carbonate is best taken with food, and the formula does not replace the original magnesium coverage.</p>
94 Value

Krebs Magnesium Potassium Complex

Nature's Way
<p>Magnesium lysinate and malate provide favorable forms at a useful amount, with modest potassium adding complementary mineral support. Serving value is strong, but the formula requires a separate calcium source when calcium is also needed.</p>
90 Value

Calcium Citrate +D3 Petites

21st Century
<p>Calcium citrate with vitamin D3 combines a practical amount, favorable absorption, and accessible serving value. The focused formula does not provide magnesium, and missing excipient details modestly limit transparency.</p>
88 Value

Albion Chelated Calcium 180 mg

Swanson Ultra
<p>Calcium glycinate chelate with a small vitamin D3 addition offers a useful balance of form quality and value. The supplied product name and serving amount conflict, so the current label should be checked, and magnesium still needs separate coverage.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  2. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  3. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  4. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  5. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  6. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  7. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  8. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  9. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  10. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  11. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  12. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  13. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  14. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  15. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  16. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  17. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  18. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  19. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  20. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  21. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  22. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  23. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  24. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  25. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  26. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  27. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  28. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  29. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  30. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  31. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  32. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  33. Predictive Model of Nail Consistency Using Scanning Electron Microscopy with Energy-Dispersive X-Ray.
    Mingorance Álvarez E; Martínez Quintana R; Pérez Pico AM; Mayordomo R · Biology · 2021
    Cross-sectional study57 participantsNail Health forCalcium
  34. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  35. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  36. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  37. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  38. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  39. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  40. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  41. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  42. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  43. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium